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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2021	Mar. 31, 2020
Revenues:
Revenues	$ 16,881	$ 13,682
Costs and expenses:
Cost of product sales	17	0
Research and development	53,121	48,894
Selling, general and administrative	15,036	10,233
Total costs and expenses	68,174	59,127
Loss from operations	(51,293)	(45,445)
Other income	21	721
Net loss	(51,272)	(44,724)
Other comprehensive income:
Unrealized gain on investments	18	56
Comprehensive loss	$ (51,254)	$ (44,668)
Basic and diluted net loss per common share (in usd per share)	$ (0.90)	$ (0.91)
Basic and diluted weighted average common shares outstanding (in shares)	57,202,846	49,012,663
Revenue from collaborative and other agreements
Revenues:
Revenues	$ 15,184	$ 12,967
Product revenue, net
Revenues:
Revenues	887	0
Revenue from government agreements
Revenues:
Revenues	$ 810	$ 715

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