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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Cash flows from operating activities    
Net loss $ (51,272) $ (44,724)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization expense 2,729 3,079
Amortization of premiums and discounts on marketable securities 367 (270)
Stock-based compensation 5,286 4,491
Changes in operating assets and liabilities:    
Accounts receivable 15,934 938
Inventory (6,172) 0
Prepaid expenses and other current assets (1,239) (1,345)
Other assets 3,673 695
Accounts payable 1,829 (2,286)
Accrued expenses and other current liabilities 855 (2,118)
Lease liabilities (683) (869)
Deferred revenue (601) (2,248)
Other non current liabilities 258 515
Net cash used in operating activities (29,036) (44,142)
Cash flows from investing activities    
Purchases of marketable securities (93,881) (61,186)
Proceeds from sale and maturities of marketable securities 60,250 73,003
Purchases of property, equipment and software (626) (1,253)
Net cash provided by (used in) investing activities (34,257) 10,564
Cash flows from financing activities    
Proceeds from issuance of common stock, net of offering costs 98,200 0
Proceeds from stock option exercises and ESPP purchases 2,458 162
Net cash provided by financing activities 100,658 162
Net change in cash and cash equivalents 37,365 (33,416)
Cash and cash equivalents at beginning of period 181,131 126,472
Cash and cash equivalents at end of period 218,496 93,056
Supplemental Cash Flow Information [Abstract]    
Property, equipment and software included in accounts payable or accruals $ 486 $ 0