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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Revenues:        
Revenues $ 30,757 $ 20,257 $ 47,638 $ 33,939
Costs and expenses:        
Cost of product sales 22 0 39 0
Research and development 55,780 57,351 108,901 106,245
Selling, general and administrative 15,234 10,216 30,270 20,449
Total costs and expenses 71,036 67,567 139,210 126,694
Loss from operations (40,279) (47,310) (91,572) (92,755)
Other income 344 425 365 1,146
Net loss (39,935) (46,885) (91,207) (91,609)
Other comprehensive income (loss):        
Unrealized gain (loss) on investments (10) (55) 8 1
Comprehensive loss $ (39,945) $ (46,940) $ (91,199) $ (91,608)
Basic net loss per common share (in usd per share) $ (0.66) $ (0.94) $ (1.56) $ (1.85)
Diluted net loss per common share (in usd per share) $ (0.66) $ (0.94) $ (1.56) $ (1.85)
Basic weighted average common shares outstanding (in shares) 60,068,315 50,018,462 58,643,496 49,515,562
Diluted weighted average common shares outstanding (in shares) 60,068,315 50,018,462 58,643,496 49,515,562
Revenue from collaborative and other agreements        
Revenues:        
Revenues $ 27,168 $ 15,636 $ 42,352 $ 28,603
Product revenue, net        
Revenues:        
Revenues 3,203 0 4,090 0
Revenue from government agreements        
Revenues:        
Revenues $ 386 $ 4,621 $ 1,196 $ 5,336