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Stockholders' Equity (Details) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 12 Months Ended
Jun. 30, 2021
Apr. 30, 2021
Nov. 30, 2020
Jun. 30, 2020
Dec. 31, 2019
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Jun. 15, 2021
Class of Stock [Line Items]                  
Common stock, shares authorized (in shares)           125,000,000 125,000,000    
Common stock, par value (in dollars per share)           $ 0.01 $ 0.01    
Proceeds from issuance of common stock, net of offering costs           $ 117,818 $ 170,456 $ 118,657  
Zai Lab | 2021 Zai Lab Agreements                  
Class of Stock [Line Items]                  
Sale of common stock (in dollars per share)                 $ 31.30
Proceeds of stock sale $ 30,000                
Undesignated Preferred Stock                  
Class of Stock [Line Items]                  
Undesignated preferred stock, shares authorized (in shares)           5,000,000      
Undesignated preferred stock, par value (in dollars per share)           $ 0.01 $ 0.01    
Undesignated preferred stock, shares issued (in shares)           0 0    
Undesignated preferred stock, shares outstanding (in shares)           0 0    
At The Market Offering                  
Class of Stock [Line Items]                  
Common stock maximum amount available for issuance     $ 100,000 $ 175,000 $ 50,000        
Sale of common stock (in shares)           3,622,186 6,612,815    
Sale of common stock (in dollars per share)           $ 27.60 $ 26.46    
Proceeds of stock sale           $ 98,200 $ 170,500    
Common Stock, Maximum Amount Available For Issuance, Increase   $ 300,000