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Collaboration and Other Agreements - Janssen (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Dec. 31, 2020
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Collaboration And Other Agreements [Line Items]        
Revenues   $ 11,101 $ 16,881  
Janssen Biotech Inc | Janssen Collaboration and License Agreement        
Collaboration And Other Agreements [Line Items]        
Non-refundable upfront payment $ 20,000      
Potential milestone payments and royalties on product sales       $ 312,000
Potential proceeds from royalties (percent) 10.00%      
Collaborative agreement transaction price       $ 22,200
Clinical trial activities selling price amount $ 2,200      
Janssen Biotech Inc | Janssen Collaboration and License Agreement | Revenues From License Agreements        
Collaboration And Other Agreements [Line Items]        
Revenues $ 20,000      
Janssen Biotech Inc | Janssen Collaboration and License Agreement | Revenue From Performance of the Research and Development Activities        
Collaboration And Other Agreements [Line Items]        
Revenues   $ 300 $ 300