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Collaboration and Other Agreements - Zai Lab (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended | 24 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | ---
Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Dec. 31, 2018 | Jun. 30, 2022 | Dec. 31, 2021 | Jun. 15, 2021 | Dec. 31, 2020
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |
Revenues |  | $ 26,007 | $ 30,757 | $ 37,108 | $ 47,638 |  |  |  |  |
Common stock, par value (in dollars per share) |  | $ 0.01 |  | $ 0.01 |  |  | $ 0.01 | $ 0.01 |  |
Deferred revenue, current |  | $ 11,565 |  | $ 11,565 |  |  | $ 11,565 | $ 20,646 |  |
Deferred revenue, net of current portion |  | 6,163 |  | 6,163 |  |  | 6,163 | 0 |  |
2018 Zai Lab Agreement | Zai Labs |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |
Non-refundable upfront payment |  |  |  |  |  | $ 25,000 |  |  |  |
Non-refundable upfront payment, net of tax withholding |  |  |  |  |  | 22,500 |  |  |  |
Nonrefundable payment tax withholding |  |  |  |  |  | $ 2,500 |  |  |  |
Potential development and regulatory milestone payments under agreement |  |  |  |  |  |  |  |  |  | $ 140,000
Development and regulatory milestones recognized |  |  |  |  |  |  | 9,000 |  |  |
Revenues |  | 400 | 0 | 5,400 | 0 |  |  |  |  |
Millstone Revenue Recognized |  |  |  | 5,000 |  |  |  |  |  |
Zai Lab Agreement, Margetuximab | Zai Labs | Maximum |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |
Potential proceeds from royalties (percent) |  |  |  |  |  | 20.00% |  |  |  |
Zai Lab Agreement, TRIDENT molecule | Zai Labs |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |
Potential proceeds from royalties (percent) |  |  |  |  |  | 10.00% |  |  |  |
Zai Lab Clinical Supply Agreements | Zai Labs |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |
Revenues |  | 100 | 500 | 300 | 1,600 |  |  |  |  |
2021 Zai Lab Agreements | Zai Labs |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |
Non-refundable upfront payment | $ 25,000 |  |  |  |  |  |  |  |  |
Potential development and regulatory milestone payments under agreement |  |  |  |  |  |  |  |  | $ 800,000 |
Deferred revenue |  | 1,800 |  | 1,800 |  |  | $ 1,800 | $ 16,100 |  |
Revenues |  | $ 14,700 | $ 14,400 | $ 15,000 | $ 14,400 |  |  |  |  |
Opt-in fee |  |  |  |  |  |  |  |  | $ 85,000 |
Proceeds of stock sale | 30,000 |  |  |  |  |  |  |  |  |
Sales of stock purchase price (in dollars per share) |  |  |  |  |  |  |  |  | $ 31.3 |
Potential commercial milestone payments under agreement |  |  |  |  |  |  |  |  | $ 600,000 |
Collaborative agreement transaction price |  |  |  |  |  |  |  |  | $ 40,400 |
Variable consideration recognized | 5,000 |  |  |  |  |  |  |  |  |
2021 Zai Lab Agreements | Zai Labs | Additional Paid-In Capital |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |
Premium received on stock purchase | $ 10,400 |  |  |  |  |  |  |  |  |

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