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Collaboration and Other Agreements - Janssen (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Dec. 31, 2020 | Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Dec. 31, 2021
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |
Revenues |  | $ 26,007 | $ 30,757 | $ 37,108 | $ 47,638 |
Janssen Biotech Inc | Janssen Collaboration and License Agreement |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |
Non-refundable upfront payment | $ 20,000 |  |  |  |  |
Potential milestone payments and royalties on product sales |  |  |  |  |  | $ 312,000
Potential proceeds from royalties (percent) | 10.00% |  |  |  |  |
Collaborative agreement transaction price |  |  |  |  |  | $ 22,200
Clinical trial activities selling price amount | $ 2,200 |  |  |  |  |
Janssen Biotech Inc | Janssen Collaboration and License Agreement | Revenues From License Agreements |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |
Revenues | $ 20,000 |  |  |  |  |
Janssen Biotech Inc | Janssen Collaboration and License Agreement | Revenue From Performance of the Research and Development Activities |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |
Revenues |  | $ 200 | $ 600 | $ 600 | $ 900 |

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