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Collaboration and Other Agreements - Janssen (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Dec. 31, 2020
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Collaboration And Other Agreements [Line Items]            
Revenues   $ 26,007 $ 30,757 $ 37,108 $ 47,638  
Janssen Biotech Inc | Janssen Collaboration and License Agreement            
Collaboration And Other Agreements [Line Items]            
Non-refundable upfront payment $ 20,000          
Potential milestone payments and royalties on product sales           $ 312,000
Potential proceeds from royalties (percent) 10.00%          
Collaborative agreement transaction price           $ 22,200
Clinical trial activities selling price amount $ 2,200          
Janssen Biotech Inc | Janssen Collaboration and License Agreement | Revenues From License Agreements            
Collaboration And Other Agreements [Line Items]            
Revenues $ 20,000          
Janssen Biotech Inc | Janssen Collaboration and License Agreement | Revenue From Performance of the Research and Development Activities            
Collaboration And Other Agreements [Line Items]            
Revenues   $ 200 $ 600 $ 600 $ 900