    <SEC-DOCUMENT>0001125345-22-000039-index.html : 20220408
    <SEC-HEADER>0001125345-22-000039.hdr.sgml : 20220408
    <ACCEPTANCE-DATETIME>20220408160635
    ACCESSION NUMBER:		0001125345-22-000039
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		4
    CONFORMED PERIOD OF REPORT:	20220519
    FILED AS OF DATE:		20220408
    DATE AS OF CHANGE:		20220408

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			MACROGENICS INC
    		CENTRAL INDEX KEY:			0001125345
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-36112
    		FILM NUMBER:		22817027

    	BUSINESS ADDRESS:
    		STREET 1:		9704 MEDICAL CENTER DRIVE
    		CITY:			Rockville
    		STATE:			MD
    		ZIP:			20850
    		BUSINESS PHONE:		301-251-5172

    	MAIL ADDRESS:
    		STREET 1:		9704 MEDICAL CENTER DRIVE
    		CITY:			ROCKVILLE
    		STATE:			MD
    		ZIP:			20850
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>def_14ax2022.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: def_14ax2022.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>imagea.jpg
    <TEXT>
    Document 2 - file: imagea.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>macrogenicscard22v1_pagex1a.jpg
    <TEXT>
    Document 3 - file: macrogenicscard22v1_pagex1a.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>macrogenicscard22v1_pagex2a.jpg
    <TEXT>
    Document 4 - file: macrogenicscard22v1_pagex2a.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>