XML 54 R26.htm IDEA: XBRL DOCUMENT v3.22.4

Stock-based Compensation (Tables)

12 Months Ended

Dec. 31, 2022

Share-Based Payment Arrangement [Abstract]

Schedule of Stock-Based Compensation Expense

The following stock-based compensation amounts were recognized for the periods indicated (in thousands):

			Year Ended December 31,
			2022						2021						2020
Research and development			$	10,094					$	11,337					$	10,833
Selling, general and administrative			10,343						11,789						9,843
Total stock-based compensation expense			$	20,437					$	23,126					$	20,676

Schedule of Employee Stock Options Award Valuation Assumptions

			Year Ended December 31,
			2022						2021						2020
Expected dividend yield			0%						0%						0%
Expected volatility			88% -92%						86% - 87%						67% - 109%
Risk-free interest rate			1.4% - 4.0%						0.6% - 1.6%						0.4% - 1.8%
Expected term			5.95 years						6.25 years						6.25 years

Schedule of Stock Option Activity

The following table summarizes stock option activity for 2022:

			Shares						Weighted-Average Exercise Price						Weighted-Average Remaining Contractual Term (Years)						Aggregate Intrinsic Value (in thousands)
Outstanding, December 31, 2021			8,373,921						$	21.47					6.6
Granted			2,794,997						9.32
Exercised			(120,900)						1.43
Forfeited			(509,569)						15.82
Expired			(439,520)						22.77
Outstanding, December 31, 2022			10,098,929						$	18.58					6.5						$	1,094
As of December 31, 2022:
Exercisable			6,694,068						$	21.35					5.5						$	424
Vested and expected to vest			9,456,075						$	18.91					6.4						$	1,009

Share-Based Payment Arrangement, Option, Exercise Price Range

The stock options outstanding and exercisable by exercise price at December 31, 2022 are as follows:

						Stock Options Outstanding																		Stock Options Exercisable
Range of Exercise Prices						Number of Shares						Weighted-Average Remaining Contractual Life in Years						Weighted-Average Exercise Price Per Share						Number of Shares						Weighted-Average Exercise Price Per Share
$0.94 - $5.00						357,628						8.8						$	3.70					143,268						$	3.76
$5.01 - $15.00						3,355,424						8.4						10.51						1,211,129						10.96
$15.01 - $25.00						4,041,994						6.1						20.21						3,152,550						20.39
$25.01 - $40.21						2,343,883						4.3						29.59						2,187,121						29.64
						10,098,929						6.5						$	18.58					6,694,068						$	21.35

Schedule of RSU Activity

The following table summarizes RSU activity for 2022:

			Shares						Weighted-Average Grant Date Fair Value
Outstanding, December 31, 2021			21,500						$	25.97
Granted			476,772						8.42
Vested			(10,445)						25.65
Forfeited or expired			(72,743)						8.74
Outstanding, December 31, 2022			415,084						$	8.83

X

- References

No definition available.

+ Details

Name:	us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

+ Details

Name:	us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of option exercise prices, by grouped ranges, including the upper and lower limits of the price range, the number of shares under option, weighted average exercise price and remaining contractual option terms.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

+ Details

Name:	us-gaap_ScheduleOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (d)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (e)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)(1)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

+ Details

Name:	us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (f)(2)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

+ Details

Name:	us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Disclosure of the number and weighted-average grant date fair value for restricted stock and restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock and restricted stock units that were granted, vested, or forfeited during the year.

+ References

No definition available.

+ Details

Name:	us-gaap_ScheduleOfSharebasedCompensationRestrictedStockAndRestrictedStockUnitsActivityTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:textBlockItemType
Balance Type:	na
Period Type:	duration