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Stockholders' Equity (Details) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 12 Months Ended
Jun. 30, 2021
Apr. 30, 2021
Nov. 30, 2020
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Jun. 15, 2021
Class of Stock [Line Items]              
Common stock, shares authorized (in shares)       125,000,000 125,000,000    
Common stock, par value (in dollars per share)       $ 0.01 $ 0.01    
Proceeds from issuance of common stock, net of offering costs       $ 1,085 $ 117,818 $ 170,456  
Zai Lab | 2021 Zai Lab Agreements              
Class of Stock [Line Items]              
Sale of common stock (in dollars per share)             $ 31.30
Proceeds of stock sale $ 30,000            
Undesignated Preferred Stock              
Class of Stock [Line Items]              
Undesignated preferred stock, shares authorized (in shares)       5,000,000      
Undesignated preferred stock, par value (in dollars per share)       $ 0.01 $ 0.01    
Undesignated preferred stock, shares issued (in shares)       0 0    
Undesignated preferred stock, shares outstanding (in shares)       0 0    
At The Market Offering              
Class of Stock [Line Items]              
Common stock maximum amount available for issuance     $ 100,000        
Sale of common stock (in shares)       160,480 3,622,186    
Sale of common stock (in dollars per share)       $ 6.87 $ 27.60    
Proceeds of stock sale       $ 1,100 $ 98,200    
Common Stock, Maximum Amount Available For Issuance, Increase   $ 300,000