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Share-based Compensation - Option, Exercise Price Range Table (Details)	12 Months Ended
	Dec. 31, 2022 $ / shares shares
Stock Options Outstanding
Number of Shares (in shares) | shares	10,098,929
Weighted-Average Remaining Contractual Life in Years	6 years 6 months
Weighted Average Exercise Price (in dollars per share)	$ 18.58
Stock Options Exercisable
Number of Shares (in shares) | shares	6,694,068
Weighted Average Exercise Price (in dollars per share)	$ 21.35
Exercise Price Range From Dollars 0.94 to 5.00 Member
Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items]
Range of Exercise Price, lower limit	0.94
Range of Exercise Price, upper limit	$ 5.00
Stock Options Outstanding
Number of Shares (in shares) | shares	357,628
Weighted-Average Remaining Contractual Life in Years	8 years 9 months 18 days
Weighted Average Exercise Price (in dollars per share)	$ 3.70
Stock Options Exercisable
Number of Shares (in shares) | shares	143,268
Weighted Average Exercise Price (in dollars per share)	$ 3.76
Exercise Price Range From Dollars 5.01 to 15.00 Member
Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items]
Range of Exercise Price, lower limit	5.01
Range of Exercise Price, upper limit	$ 15.00
Stock Options Outstanding
Number of Shares (in shares) | shares	3,355,424
Weighted-Average Remaining Contractual Life in Years	8 years 4 months 24 days
Weighted Average Exercise Price (in dollars per share)	$ 10.51
Stock Options Exercisable
Number of Shares (in shares) | shares	1,211,129
Weighted Average Exercise Price (in dollars per share)	$ 10.96
Exercise Price Range From Dollars 15.01 to 25.00 Member
Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items]
Range of Exercise Price, lower limit	15.01
Range of Exercise Price, upper limit	$ 25.00
Stock Options Outstanding
Number of Shares (in shares) | shares	4,041,994
Weighted-Average Remaining Contractual Life in Years	6 years 1 month 6 days
Weighted Average Exercise Price (in dollars per share)	$ 20.21
Stock Options Exercisable
Number of Shares (in shares) | shares	3,152,550
Weighted Average Exercise Price (in dollars per share)	$ 20.39
Exercise Price Range From Dollars 25.01 to 40.21 Member
Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items]
Range of Exercise Price, lower limit	25.01
Range of Exercise Price, upper limit	$ 40.21
Stock Options Outstanding
Number of Shares (in shares) | shares	2,343,883
Weighted-Average Remaining Contractual Life in Years	4 years 3 months 18 days
Weighted Average Exercise Price (in dollars per share)	$ 29.59
Stock Options Exercisable
Number of Shares (in shares) | shares	2,187,121
Weighted Average Exercise Price (in dollars per share)	$ 29.64

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