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Revenue- Provention (Details) - USD ($) $ / shares in Units, $ in Thousands	1 Months Ended		3 Months Ended
	Nov. 30, 2022	May 31, 2018	Mar. 31, 2023	Mar. 31, 2022
Collaboration And Other Agreements [Line Items]
Revenues			$ 24,496	$ 11,101
Provention Bio
Collaboration And Other Agreements [Line Items]
Collaborative agreement transaction price		$ 6,100
Collaborative Agreement Consideration Received Common Stock Warrants Number Of Shares		2,432,688
Provention Bio | Revenues From License Agreements
Collaboration And Other Agreements [Line Items]
Revenues		$ 6,100
Provention Bio | Provention PRV3279 | Provention License Agreement
Collaboration And Other Agreements [Line Items]
Collaborative Agreement Consideration Received Common Stock Warrant Exercise Price Per Share		$ 2.5
Potential development and regulatory milestone payments under agreement		$ 65,000
Potential commercial milestone payments under agreement		$ 225,000
Provention Bio | Provention PRV031 | Asset Purchase Agreement
Collaboration And Other Agreements [Line Items]
Collaborative Agreement Consideration Received Common Stock Warrant Exercise Price Per Share		$ 2.5
Potential development and regulatory milestone payments under agreement		$ 170,000
Potential commercial milestone payments under agreement		225,000
Development and regulatory milestones recognized	$ 60,000
Potential Milestone Payment To Third Parties For Intellectual Property Under Agreement		$ 1,300
Revenues			400
Receivable from collaboration partner			$ 30,000

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