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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Income (Loss)
Beginning balance (in shares) at Dec. 31, 2021   61,307,428      
Beginning balance at Dec. 31, 2021 $ 239,618 $ 613 $ 1,213,002 $ (973,936) $ (61)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Share-based compensation 5,224   5,224    
Stock plan activity (in shares)   25,646      
Stock plan related activity 37   37    
Unrealized gain (loss) on investments (222)       (222)
Net loss (66,443)     (66,443)  
Ending balance (in shares) at Mar. 31, 2022   61,333,074      
Ending balance at Mar. 31, 2022 178,214 $ 613 1,218,263 (1,040,379) (283)
Beginning balance (in shares) at Dec. 31, 2022   61,701,467      
Beginning balance at Dec. 31, 2022 142,013 $ 617 1,235,095 (1,093,694) (5)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Share-based compensation $ 4,788   4,788    
Shares, Granted (in shares) 2,914,405        
Stock plan activity (in shares)   42,098      
Stock plan related activity $ (154)   (154)    
Issuance of common stock, net of offering costs (in shares)   95,000      
Issuance of common stock, net of offering costs 617 $ 1 616    
Unrealized gain (loss) on investments 13       13
Net loss (38,009)     (38,009)  
Ending balance (in shares) at Mar. 31, 2023   61,838,565      
Ending balance at Mar. 31, 2023 $ 109,268 $ 618 $ 1,240,345 $ (1,131,703) $ 8