Potential Development and Regulatory Milestone Payments Under Agreement

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- Definition

Right of Use asset and Lease Liability Increase

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No definition available.

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- Definition

Amount of lease cost recognized by lessee for lease contract.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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- Definition

Discount rate used by lessee to determine present value of operating lease payments.

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Amount of lessee's undiscounted obligation for lease payment for operating lease.

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Amount of lessee's undiscounted obligation for lease payment for operating lease due after fifth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

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- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

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- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in fifth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

+ References

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- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

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Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in third fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

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- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in second fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

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- Definition

Amount of lessee's undiscounted obligation for lease payments in excess of discounted obligation for lease payments for operating lease.

+ References

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- Definition

Term of lessee's operating lease renewal, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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- Definition

Amount of single lease cost, calculated by allocation of remaining cost of lease over remaining lease term. Includes, but is not limited to, single lease cost, after impairment of right-of-use asset, calculated by amortization of remaining right-of-use asset and accretion of lease liability.

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Present value of lessee's discounted obligation for lease payments from operating lease.

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Amount of cash outflow from operating lease, excluding payments to bring another asset to condition and location necessary for its intended use.

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Amount of lessee's right to use underlying asset under operating lease.

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Weighted average remaining lease term for operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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Amount of sublease income excluding finance and operating lease expense.

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Amount of variable lease cost, excluded from lease liability, recognized when obligation for payment is incurred for finance and operating leases.

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Commitments and Contingencies (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021	Mar. 31, 2022
Lessee, Lease, Description [Line Items]
Right of use asset and lease liability increase	$ 14,000
Weighted average lease term (in years)	11 years	11 years 1 month 6 days
Discount rate	12.00%	12.00%
Operating lease payments	$ 5,900	$ 6,900
Operating lease, ROU Assets	23,846	27,335
Operating lease cost	7,459	5,597
Variable lease cost	1,316	1,451
Sublease Income	(1,109)	(1,076)
Lease, cost	7,666	5,972
2024	4,004
2025	5,084
2026	4,209
2027	4,927
2028	6,049
Thereafter	46,003
Total lease payments	70,276
Less: imputed interest	(36,306)
Operating lease liabilities	33,970
Research and development	$ 166,583	207,026	$ 214,577
Minimum
Lessee, Lease, Description [Line Items]
Lease renewal term (in years)	5 years
Synaffix B.V.
Lessee, Lease, Description [Line Items]
Potential development and regulatory milestone payments				$ 2,800,000
Research and development	$ 2,800	$ 1,000