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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Loss
Balance (in shares) at Dec. 31, 2020   56,244,771      
Balance at Dec. 31, 2020 $ 295,884 $ 562 $ 1,067,150 $ (771,821) $ (7)
Share-based compensation 23,126   23,126    
Issuance of common stock, net of offering costs (in shares)   4,580,653      
Issuance of common stock, net of offering costs 117,818 $ 46 117,772    
Stock plan related activity (in shares)   482,004      
Stock plan related activity 4,959 $ 5 4,954    
Unrealized Gain (Loss) on Investments (54)       (54)
Net loss (202,115)     (202,115)  
Balance (in shares) at Dec. 31, 2021   61,307,428      
Balance at Dec. 31, 2021 239,618 $ 613 1,213,002 (973,936) (61)
Share-based compensation 20,438   20,438    
Issuance of common stock, net of offering costs (in shares)   160,480      
Issuance of common stock, net of offering costs 1,085 $ 2 1,083    
Stock plan related activity (in shares)   233,559      
Stock plan related activity 574 $ 2 572    
Unrealized Gain (Loss) on Investments 56       56
Net loss (119,758)     (119,758)  
Balance (in shares) at Dec. 31, 2022   61,701,467      
Balance at Dec. 31, 2022 142,013 $ 617 1,235,095 (1,093,694) (5)
Share-based compensation 18,373   18,373    
Issuance of common stock, net of offering costs (in shares)   167,270      
Issuance of common stock, net of offering costs 1,039 $ 2 1,037    
Stock plan related activity (in shares)   201,890      
Stock plan related activity 247 $ 2 245    
Unrealized Gain (Loss) on Investments (1)       (1)
Net loss (9,058)     (9,058)  
Balance (in shares) at Dec. 31, 2023   62,070,627      
Balance at Dec. 31, 2023 $ 152,613 $ 621 $ 1,254,750 $ (1,102,752) $ (6)