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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Revenues:        
Revenues $ 10,797 $ 13,136 $ 19,901 $ 37,632
Costs and expenses:        
Cost of product sales 176 258 446 371
Cost of manufacturing services 2,647 919 4,493 4,329
Research and development 51,732 43,229 97,760 89,101
Selling, general and administrative 14,423 13,692 29,133 27,219
Total costs and expenses 68,978 58,098 131,832 121,020
Loss from operations (58,181) (44,962) (111,931) (83,388)
Gain on modification of debt 0 100,930 0 100,930
Interest and other income 2,523 2,275 5,216 3,348
Interest and other expense (6) (774) (1,139) (1,430)
Net loss (55,664) 57,469 (107,854) 19,460
Other comprehensive income (loss):        
Unrealized gain (loss) on investments 11 (80) (18) (67)
Comprehensive income (loss) $ (55,653) $ 57,389 $ (107,872) $ 19,393
Net income (loss) per common share:        
Basic net loss per common share (in usd per share) $ (0.89) $ 0.93 $ (1.73) $ 0.31
Diluted net loss per common share (in usd per share) $ (0.89) $ 0.92 $ (1.73) $ 0.31
Weighted average common shares outstanding:        
Basic weighted average common shares outstanding (in shares) 62,663,677 61,880,096 62,477,108 61,845,151
Diluted weighted average common shares outstanding (in shares) 62,663,677 62,261,646 62,477,108 62,030,710
Collaborative and other agreements        
Revenues:        
Revenues $ 2,065 $ 6,021 $ 3,514 $ 22,708
Product sales, net        
Revenues:        
Revenues 5,248 5,062 10,109 8,552
Government agreements        
Revenues:        
Revenues 493 466 851 749
Contract Manufacturing        
Revenues:        
Revenues 2,893 1,587 5,169 5,202
RevenueFromRoyalityAgreementsMember        
Revenues:        
Revenues $ 98 $ 0 $ 258 $ 421