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In-Licensing Arrangement (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Mar. 31, 2022
In-Licensing arrangement [Line Items]          
Research and development $ 40,543 $ 30,131 $ 138,304 $ 119,232  
Synaffix B.V.          
In-Licensing arrangement [Line Items]          
Potential development and regulatory milestone payments under agreement         $ 2,800,000
Research and development $ 0 $ 0 $ 3,400 $ 1,700