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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Cash flows from operating activities    
Net income (loss) $ (51,545) $ 37,014
Adjustments to reconcile net income (loss) to net cash used in operating activities:    
Depreciation and amortization expense 5,487 7,745
Amortization of premiums and discounts on marketable securities (2,625) (3,276)
Stock-based compensation 18,174 14,014
Gain on modification of debt 0 (150,930)
Non-cash interest expense recognized 0 1,430
Operating Lease, Noncash Expense 1,835 2,703
Other non-cash items 2 423
(Gain) loss on disposal of assets (57) 111
Changes in operating assets and liabilities:    
Accounts receivable 1,616 30,911
Inventory (2,023) 385
Prepaid expenses and other current assets 108 1,651
Other non current assets 200 (7)
Accounts payable 170 (1,607)
Accrued expenses and other current liabilities 648 (3,388)
Lease liabilities 128 (723)
Deferred revenue (2,084) 13,376
Net cash used in operating activities (29,966) (50,168)
Cash flows from investing activities    
Purchases of marketable securities (63,394) (217,216)
Proceeds from sale and maturities of marketable securities 174,150 99,390
Purchases of property, equipment and software (3,086) (1,144)
Proceeds from Sale of Machinery and Equipment 160 64
Net cash provided by (used in) investing activities 107,830 (118,906)
Cash flows from financing activities    
Proceeds from issuance of common stock, net of offering costs 0 616
Proceeds from stock option exercises and ESPP purchases 3,276 279
Taxes paid related to net share settlement of equity awards (2,471) (306)
Principal payments on royalty monetization arrangement 0 (156)
Net proceeds from sale of future royalties 0 149,655
Net cash provided by financing activities 805 150,088
Net change in cash and cash equivalents 78,669 (18,986)
Cash and cash equivalents at beginning of period 100,956 108,884
Cash and cash equivalents at end of period 179,625 89,898
Supplemental Cash Flow Information    
Property, equipment and software included in accounts payable or accruals $ 0 $ 166