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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Revenues:      
Revenues $ 149,962 $ 58,749 $ 151,941
Costs and expenses:      
Cost of product sales 847 619 3,351
Cost of manufacturing services 11,452 7,603 4,033
Research and development 177,194 166,583 207,026
Selling, general and administrative 71,047 52,188 58,949
Total costs and expenses 260,540 226,993 273,359
Loss from operations (110,578) (168,244) (121,418)
Gain on royalty monetization arrangement 0 150,930 0
Gain on sale of MARGENZA 36,250 0 0
Interest and other income 9,421 9,686 1,660
Interest and other expense (1,115) (1,430) 0
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest (66,022) (9,058) (119,758)
Income tax provision 944 0 0
Net loss (66,966) (9,058) (119,758)
Other comprehensive income (loss):      
Unrealized gain (loss) on investments 10 (1) 56
Comprehensive loss $ (66,956) $ (9,059) $ (119,702)
Basic and diluted net loss per common share, basic (in dollars per share) $ (1.07) $ (0.15) $ (1.95)
Basic and diluted net loss per common share, diluted (in dollars per share) $ (1.07) $ (0.15) $ (1.95)
Basic weighted average number of common shares outstanding (in shares) 62,621,185 61,929,198 61,433,124
Diluted weighted average number of common shares outstanding (in shares) 62,621,185 61,929,198 61,433,124
Revenue from collaborative agreements      
Revenues:      
Revenues $ 118,856 $ 29,421 $ 119,303
Revenue from government agreements      
Revenues:      
Revenues 1,623 1,556 1,923
Product      
Revenues:      
Revenues 16,426 17,939 16,727
Contract Manufacturing      
Revenues:      
Revenues $ 13,057 $ 9,833 $ 13,988