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Revenue- Incyte Corporation (Details) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended | 24 Months Ended | 87 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Aug. 31, 2024 USD ($) | Jun. 30, 2024 USD ($) | Jan. 31, 2022 USD ($) | Mar. 31, 2025 USD ($) | Mar. 31, 2024 USD ($) | Jun. 30, 2020 | Dec. 31, 2017 USD ($) | Dec. 31, 2018 USD ($) | Mar. 31, 2025 USD ($) | Dec. 31, 2024 USD ($) | Jul. 31, 2022 USD ($) | Dec. 31, 2020 USD ($) performanceObligation
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  | $ 13,192 | $ 9,104 |  |  |  |  |  |  |
Deferred revenue, current |  |  |  | 15,620 |  |  |  |  | $ 15,620 | $ 16,319 |  |
Deferred revenue, net of current portion |  |  |  | 55,938 |  |  |  |  | 55,938 | 55,503 |  |
Incyte Corporation | Incyte MGA012 Agreement |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable upfront payment |  |  |  |  |  |  | $ 150,000 |  |  |  |  |
Potential commercial milestone payments under agreement |  |  |  |  |  |  |  |  |  |  |  | $ 330,000
Potential development and regulatory milestone payments under agreement |  |  |  |  |  |  |  |  |  |  |  | 210,000
Development and regulatory milestones recognized | $ 100,000 |  |  |  |  |  |  |  | 215,000 |  |  |
Collaborative agreement transaction price |  |  |  |  |  |  |  |  |  |  |  | $ 154,000
Variable consideration recognized |  |  |  |  |  |  |  | $ 4,000 |  |  |  |
Number of performance obligations | performanceObligation |  |  |  |  |  |  |  |  |  |  |  | 2
Gilead | Gilead First Research Program |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  | $ 3,300 |  | 5,400 | 700 |  |  |  |  |  |  |
Deferred revenue |  |  |  | 5,600 |  |  |  |  | 5,600 | 11,000 |  |
Deferred revenue, current |  |  |  | 5,600 |  |  |  |  | 5,600 | 11,000 |  |
Minimum | Incyte Corporation | Incyte MGA012 Agreement |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Potential proceeds from royalties (percent) |  |  |  |  |  | 15.00% |  |  |  |  |  |
Maximum | Incyte Corporation | Incyte MGA012 Agreement |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Potential proceeds from royalties (percent) |  |  |  |  |  | 24.00% |  |  |  |  |  |
Revenues From License Agreements | Incyte Corporation | Incyte MGA012 Agreement |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  | 400 | 200 |  | $ 150,000 |  |  |  |  |
Revenues From License Agreements | Incyte Corporation | Incyte Commercial Supply Agreement |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  | 400 | 400 |  |  |  |  |  |  |
RevenuesFromCMOAgreementsMember | Incyte Corporation |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable upfront payment |  |  | $ 10,000 |  |  |  |  |  |  |  |  |
Annual Fixed Payments |  |  | $ 14,400 |  |  |  |  |  |  |  |  |
Revenues |  |  |  | 5,000 | $ 2,100 |  |  |  |  |  |  |
Deferred revenue |  |  |  | 1,800 |  |  |  |  | 1,800 | 3,400 |  |
Deferred revenue, current |  |  |  | 1,800 |  |  |  |  | 1,800 | $ 3,400 |  |
RevenuesFromCMOAmendmentAgreement | Incyte Corporation |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Annual Fixed Payments |  |  |  | 41,700 |  |  |  |  | 41,700 |  |  |
Additional Payments |  |  |  | $ 13,500 |  |  |  |  | $ 13,500 |  | $ 5,100 |
Manufacturing Services | Incyte Corporation |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Extension term |  |  |  |  |  |  |  |  |  |  | 1 year |
Manufacturing Services | Incyte Corporation | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2022-02-01 |  |  |  |  |  |  |  |  |  |  |  |
Collaboration And Other Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenue, remaining performance obligation, expected timing of satisfaction |  |  | 3 years |  |  |  |  |  |  |  |  |

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