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Stock-Based Compensation - Stock-Based Compensation Expense (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 3 Months Ended |  |  |
--- | --- | --- | --- | --- | ---
May 31, 2017 | Mar. 31, 2025 | Mar. 31, 2024 | Dec. 31, 2024 | May 23, 2024 | May 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Options outstanding (in shares) |  | 14,468,007 |  | 12,939,517 |  |
Weighted-average exercise price of stock options outstanding (in dollars per share) |  | $ 13.37 |  | $ 14.80 |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |  |
Stock-based compensation expense |  | $ 4,386 | $ 5,553 |  |  |
Research and Development |  |  |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |  |
Stock-based compensation expense |  | 3,083 | 2,829 |  |  |
General and Administrative |  |  |  |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |  |  |  |
Stock-based compensation expense |  | $ 1,303 | $ 2,724 |  |  |
2016 Employee Stock Purchase Plan |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate | 10.00% |  |  |  |  |
Share-based compensation, number of shares authorized (in shares) | 800,000 |  |  |  |  |
Offering period | 6 months |  |  |  |  |
Purchase price of common stock percent of the fair market value | 85.00% |  |  |  |  |
StockIncentivePlan2023Member |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Share-based compensation, number of shares authorized (in shares) |  |  |  |  | 6,850,000 | 4,850,000
TwoThousandSixteenEmployeeStockPurchasePlanMember |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Common stock purchased (in shares) |  | 0 | 0 |  |  |

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