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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Revenues:    
Revenues $ 13,192 $ 9,104
Costs and expenses:    
Cost of product sales 0 270
Cost of manufacturing services 5,400 1,846
Research and development 39,698 46,029
Selling, general and administrative 10,718 14,709
Total costs and expenses 55,816 62,854
Loss from operations (42,624) (53,750)
Interest and other income 1,679 2,693
Interest and other expense (91) (1,133)
Net loss (41,036) (52,190)
Other comprehensive loss:    
Unrealized loss on investments (5) (29)
Comprehensive loss $ (41,041) $ (52,219)
Net income (loss) per common share:    
Basic net loss per common share (in usd per share) $ (0.65) $ (0.84)
Diluted net loss per common share (in usd per share) $ (0.65) $ (0.84)
Weighted average common shares outstanding:    
Basic weighted average common shares outstanding (in shares) 62,965,415 62,290,538
Diluted weighted average common shares outstanding (in shares) 62,965,415 62,290,538
Collaborative and other agreements    
Revenues:    
Revenues $ 7,042 $ 1,609
Product sales, net    
Revenues:    
Revenues 0 4,861
Contract Manufacturing    
Revenues:    
Revenues 6,150 2,276
Government Contract    
Revenues:    
Revenues $ 0 $ 358