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v3.25.3

Segment Reporting (Details) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 USD ($) | Jun. 30, 2025 USD ($) | Mar. 31, 2025 USD ($) | Sep. 30, 2024 USD ($) | Jun. 30, 2024 USD ($) | Mar. 31, 2024 USD ($) | Sep. 30, 2025 USD ($) segment | Sep. 30, 2024 USD ($)
Segment Reporting [Abstract] |  |  |  |  |  |  |  |
Number of reportable segments | segment |  |  |  |  |  |  | 1 |
Number of operating segments | segment |  |  |  |  |  |  | 1 |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Total revenues | $ 72,839 |  |  | $ 110,708 |  |  | $ 108,273 | $ 130,609
Cost of product sales | 0 |  |  | 168 |  |  | 0 | 614
Cost of manufacturing services | 11,589 |  |  | 1,702 |  |  | 25,894 | 6,195
Research and development | 32,709 |  |  | 40,543 |  |  | 113,198 | 138,304
Selling, general and administrative | 9,905 |  |  | 14,104 |  |  | 29,925 | 43,237
Net loss | 16,822 | $ (36,251) | $ (41,036) | 56,309 | $ (55,664) | $ (52,190) | (60,465) | (51,545)
Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Total revenues | 72,839 |  |  | 110,708 |  |  | 108,273 | 130,609
Cost of product sales | 0 |  |  | 168 |  |  | 0 | 614
Cost of manufacturing services | 11,589 |  |  | 1,702 |  |  | 25,894 | 6,195
Research and development | 32,709 |  |  | 40,543 |  |  | 113,198 | 138,304
Selling, general and administrative | 9,905 |  |  | 14,104 |  |  | 29,925 | 43,237
Other segment income (loss), net | (1,814) |  |  | 2,118 |  |  | 279 | 6,196
Net loss | 16,822 |  |  | 56,309 |  |  | (60,465) | (51,545)
Lorigerlimab | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | 7,763 |  |  | 6,268 |  |  | 27,188 | 26,897
MGC030 | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | 7,045 |  |  | 4,000 |  |  | 15,217 | 8,900
MGC028 | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | 3,443 |  |  | 4,280 |  |  | 12,118 | 20,158
Vobramitanmab duocarmazine | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | 3,316 |  |  | 10,514 |  |  | 15,969 | 32,221
Next-generation T-cell engagers | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | 3,104 |  |  | 1,994 |  |  | 8,894 | 6,575
MGC026 | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | 3,028 |  |  | 3,010 |  |  | 11,942 | 10,865
MGD024 | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | 2,125 |  |  | 2,341 |  |  | 7,032 | 7,285
ADC | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | 862 |  |  | 1,541 |  |  | 4,718 | 5,918
Margetuximab | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | 0 |  |  | 2,089 |  |  | 650 | 8,077
Other programs | Main Segment |  |  |  |  |  |  |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |  |  |  |  |  |  |
Research and development | $ 2,023 |  |  | $ 4,506 |  |  | $ 9,470 | $ 11,408

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