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Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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- Definition

The highest percentage of annual salary that an employee is permitted to utilize with respect to the plan.

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- Definition

Number of shares authorized for issuance under share-based payment arrangement.

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- Definition

Number of options outstanding, including both vested and non-vested options.

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Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

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Number of shares issued under share-based payment arrangement.

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Purchase price of common stock expressed as a percentage of its fair value.

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Stock-Based Compensation - Stock-Based Compensation Expense (Details) - USD ($) $ / shares in Units, $ in Thousands	1 Months Ended	3 Months Ended		9 Months Ended
	May 31, 2017	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024	May 21, 2025	Dec. 31, 2024	May 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options outstanding (in shares)		15,210,035		15,210,035			12,939,517
Weighted-average exercise price of stock options outstanding (in dollars per share)		$ 12.47		$ 12.47			$ 14.80
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Stock-based compensation expense		$ 3,548	$ 5,970	$ 11,625	$ 18,174
Research and Development
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Stock-based compensation expense		2,219	2,940	7,282	9,033
General and Administrative
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Stock-based compensation expense		$ 1,329	$ 3,030	$ 4,343	$ 9,141
2016 Employee Stock Purchase Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate	10.00%
Share-based compensation, number of shares authorized (in shares)	800,000
Offering period	6 months
Purchase price of common stock percent of the fair market value	85.00%
StockIncentivePlan2023Member
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation, number of shares authorized (in shares)						8,100,000		4,850,000
TwoThousandSixteenEmployeeStockPurchasePlanMember
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Common stock purchased (in shares)				56,880	44,129