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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Cash flows from operating activities    
Net loss $ (60,465) $ (51,545)
Adjustments to reconcile net income loss to net cash used in operating activities:    
Depreciation and amortization expense 5,467 5,487
Amortization of premiums and discounts on marketable securities (1,004) (2,625)
Stock-based compensation 11,625 18,174
Non-cash royalty revenue (3,333) 0
Non-cash interest expense recognized 3,916 0
Non-cash lease expense 1,204 1,835
Other adjustments 0 (55)
Changes in operating assets and liabilities:    
Accounts receivable (64,921) 1,616
Inventory (8,750) (2,023)
Prepaid expenses and other current assets 3,800 108
Other non current assets 164 200
Accounts payable 921 170
Accrued expenses and other current liabilities (5,913) 648
Lease liabilities (452) 128
Deferred revenue (5,680) (2,084)
Other non current liabilities (640) 0
Net cash used in operating activities (124,061) (29,966)
Cash flows from investing activities    
Purchases of marketable securities (119,490) (63,394)
Proceeds from sale and maturities of marketable securities 73,053 174,150
Purchases of property, equipment and software (1,670) (3,086)
Proceeds from sales of equipment 0 160
Net cash (used in) provided by investing activities (48,107) 107,830
Cash flows from financing activities    
Proceeds from stock option exercises and ESPP purchases 66 3,276
Taxes paid related to net share settlement of equity awards (282) (2,471)
Net proceeds from sale of future royalties 69,673 0
Net cash provided by financing activities 69,457 805
Net change in cash and cash equivalents (102,711) 78,669
Cash and cash equivalents at beginning of period 182,840 100,956
Cash and cash equivalents at end of period 80,129 179,625
Supplemental cash flow disclosures    
Cash paid for income taxes 105 0
Non-cash operating and investing activities    
Property and equipment included in accounts payable or accruals $ 7 $ 0