XML 103 R29.htm IDEA: XBRL DOCUMENT
v3.26.1

Segments (Tables) | 3 Months Ended
--- | ---
Mar. 31, 2026
Segment Reporting [Abstract] |
Schedule of Segment Reporting Information, by Segment | Additional disaggregated significant segment expenses on a functional basis, that are not separately presented on the Company’s condensed consolidated statements of operations, are presented below (in thousands):
| Three months ended March 31, |  |
| 2026 |  | 2025 |  |  |  |
Personnel expenses excluding stock-based compensation | $ | 6,249 |  |  | $ | 5,783 |  |  |  |  |
Stock-based compensation | 2,824 |  |  | 1,968 |  |  |  |  |
Direct external program expenses: |  |  |  |  |  |  |
ALTO-100 | 1,764 |  |  | 1,124 |  |  |  |  |
ALTO-300 | 1,507 |  |  | 922 |  |  |  |  |
ALTO-101 | 5,356 |  |  | 969 |  |  |  |  |
ALTO-203 | 6 |  |  | 737 |  |  |  |  |
ALTO-207 | 4,143 |  |  | — |  |  |  |  |
Other research and development (a) | 1,198 |  |  | 1,129 |  |  |  |  |
General and administrative (b) | 4,091 |  |  | 3,044 |  |  |  |  |
Loss from operations | $ | 27,138 |  |  | $ | 15,676 |  |  |  |  |
(a) Other research and development expenses primarily consists of license fees, facility charges, third party consultant costs, early research costs related to other product candidates, and other unallocated costs. (b) General and administrative costs include professional fees, insurance, consultant fees and facility charges.

X
- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
Name: | us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- References No definition available. + Details
Name: | us-gaap_SegmentReportingAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration