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Insider Trading Arrangements
3 Months Ended
Mar. 31, 2026
shares
Trading Arrangements, by Individual  
Rule 10b5-1 Arrangement Adopted false
Non-Rule 10b5-1 Arrangement Adopted false
Non-Rule 10b5-1 Arrangement Terminated false
Amit Etkin [Member]  
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement
On March 13, 2026, Amit Etkin, M.D., Ph.D., our President, Chief Executive Officer, and Chair of the Board, terminated a Rule 10b5-1 trading plan effective March 17, 2026. No sales of common stock occurred under the plan prior to its termination. Prior to its termination, the plan had provided for the potential sale of up to 100,000 shares of our common stock at each of two specified price points (60,000 shares to be sold at $35.00 and 40,000 shares to be sold at $80.00). Transactions under Dr. Etkin’s plan were based upon pre-established dates and stock price thresholds and would only occur upon the expiration of the applicable mandatory cooling-off period. Dr. Etkin’s plan had a termination date of December 31, 2026, or the date all shares subject to the plan had been sold.
Name Amit Etkin, M.D., Ph.D.
Title President, Chief Executive Officer, and Chair of the Board
Rule 10b5-1 Arrangement Terminated true
Termination Date March 13, 2026
Aggregate Available 100,000
Nicholas Smith [Member]  
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement
On March 11, 2026, Nicholas Smith, our Chief Financial Officer and Chief Business Officer, terminated a Rule 10b5-1 trading plan effective March 13, 2026. No sales of common stock occurred under the plan prior to its termination. Prior to its termination, the plan had provided for the potential sale of up to 14,376 shares of our common stock at a price per share of $45.00. Transactions under Mr. Smith’s plan were based upon pre-established dates and stock price thresholds and would only occur upon the expiration of the applicable mandatory cooling-off period. Mr. Smith’s plan had a termination date of December 31, 2026, or the date all shares subject to the plan had been sold.
Name Nicholas Smith
Title Chief Financial Officer and Chief Business Officer
Rule 10b5-1 Arrangement Terminated true
Termination Date March 11, 2026
Aggregate Available 14,376