<SEC-DOCUMENT>0000905148-25-000401.txt : 20250206
<SEC-HEADER>0000905148-25-000401.hdr.sgml : 20250206
<ACCEPTANCE-DATETIME>20250206163531
ACCESSION NUMBER:		0000905148-25-000401
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20250204
FILED AS OF DATE:		20250206
DATE AS OF CHANGE:		20250206

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Hoffmann Bernhard
		CENTRAL INDEX KEY:			0001830354
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34079
		FILM NUMBER:		25597926

	MAIL ADDRESS:	
		STREET 1:		37000 GRAND RIVER AVE
		STREET 2:		SUITE 120
		CITY:			FARMINGTON HILLS
		STATE:			MI
		ZIP:			48335

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Opus Genetics, Inc.
		CENTRAL INDEX KEY:			0001228627
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				113516358
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		8 DAVIS DRIVE
		STREET 2:		SUITE 220
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27709
		BUSINESS PHONE:		248-681-9815

	MAIL ADDRESS:	
		STREET 1:		8 DAVIS DRIVE
		STREET 2:		SUITE 220
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27709

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Ocuphire Pharma, Inc.
		DATE OF NAME CHANGE:	20201109

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	REXAHN PHARMACEUTICALS, INC.
		DATE OF NAME CHANGE:	20050516

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CORPORATE ROAD SHOW DOT COM INC
		DATE OF NAME CHANGE:	20030423
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        <issuerName>Opus Genetics, Inc.</issuerName>
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            <rptOwnerStreet1>C/O OPUS GENETICS, INC.</rptOwnerStreet1>
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    <remarks>Exhibit List: Exhibit 24 - Power of Attorney</remarks>

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    <div style="text-align: center; font-weight: bold;">POWER OF ATTORNEY</div>
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    <div style="text-indent: 36pt;">Know all by these presents, that the undersigned hereby makes, constitutes and appoints each of Amy Rabourn and Sharon Goldbach, or either of them acting individually, and with full power of substitution, the
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            <div style="color: #1F1F1F;">prepare, execute in the undersigned's name and on the undersigned's behalf, and submit to the U.S. Securities and Exchange Commission (the "SEC") a Form ID, including amendments thereto, and any other documents
              necessary or appropriate to obtain codes and passwords enabling the undersigned to make electronic filings with the SEC of reports required by Section 16(a) of the Securities Exchange Act of 1934 or any rule or regulation of the SEC;</div>
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            <div><font style="color: #1F1F1F;">execute for and on behalf of the undersigned, in the undersigned's capacity as an officer and/or director of </font>Ocuphire Pharma, Inc., <font style="color: #1F1F1F;">a Delaware corporation (the
                "Company"), Forms 3, 4, and 5, including amendments thereto, in accordance with Section 16(a) of the Securities Exchange Act of 1934 and the rules and regulations thereunder;</font></div>
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            <div style="color: #1F1F1F;">do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form 3, 4, or 5, complete and execute any amendment or amendments thereto,
              and timely file such form with the SEC and any stock exchange or similar authority; and</div>
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            <div style="color: #1F1F1F;">take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best interest of, or legally required by, the undersigned,
              it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in
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    <div style="text-indent: 36pt; color: #1F1F1F;">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of
      any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such
      attorney-in-fact, or such attorney-in-fact's substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The undersigned acknowledges that the foregoing
      attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned's responsibilities to comply with Section 16 of the Securities Exchange Act of 1934.</div>
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    <div style="text-indent: 36pt;"><font style="color: #1F1F1F;">This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms 3, 4, and 5 with respect to the undersigned's holdings of and
        transactions in securities issued by the Company, unless earlier (a) revoked by the undersigned </font><font style="color: #3F3F3F;">i</font><font style="color: #1F1F1F;">n a signed writing delivered to the foregoing attorneys-in-fact or (b)
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    <div style="text-indent: 36pt; color: #1F1F1F;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 1st <font style="color: #1F1F1F;">day of </font>February,<font style="color: #1F1F1F;"> 2024.</font> </div>
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            <td style="width: 33.33%; text-align: center; border-bottom: 2px solid rgb(0, 0, 0);"><font style="font-family: 'Times New Roman',Times,serif; color: rgb(31, 31, 31);">/s/ Bernhard Hoffmann<br>
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            <td style="width: 33.33%; text-align: center; border-bottom: 2px solid rgb(0, 0, 0);"><font style="font-family: 'Times New Roman',Times,serif; color: rgb(31, 31, 31);">Bernhard Hoffmann<br>
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