<SEC-DOCUMENT>0001140361-25-040796.txt : 20251106
<SEC-HEADER>0001140361-25-040796.hdr.sgml : 20251106
<ACCEPTANCE-DATETIME>20251106163147
ACCESSION NUMBER:		0001140361-25-040796
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		16
CONFORMED PERIOD OF REPORT:	20251105
ITEM INFORMATION:		Entry into a Material Definitive Agreement
ITEM INFORMATION:		Other Events
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20251106
DATE AS OF CHANGE:		20251106

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Opus Genetics, Inc.
		CENTRAL INDEX KEY:			0001228627
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				113516358
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34079
		FILM NUMBER:		251458982

	BUSINESS ADDRESS:	
		STREET 1:		8 DAVIS DRIVE
		STREET 2:		SUITE 220
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27713
		BUSINESS PHONE:		248-681-9815

	MAIL ADDRESS:	
		STREET 1:		8 DAVIS DRIVE
		STREET 2:		SUITE 220
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27713

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Ocuphire Pharma, Inc.
		DATE OF NAME CHANGE:	20201109

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	REXAHN PHARMACEUTICALS, INC.
		DATE OF NAME CHANGE:	20050516

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CORPORATE ROAD SHOW DOT COM INC
		DATE OF NAME CHANGE:	20030423
</SEC-HEADER>
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<div><span style="font-size: 14pt;">UNITED






        STATES</span></div>
</div>

    <div><span style="font-size: 14pt;"> </span></div>

    <div style="text-align: center;"><span style="font-size: 14pt;"><span style="font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION</span></span> </div>

    <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif; font-size: 12pt; font-weight: bold;">Washington, D.C. 20549</div>

    <div><br/>
    </div>

    <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif; font-size: 18pt; font-weight: bold;">FORM <ix:nonNumeric name="dei:DocumentType" id="Fact_e5ee9e73a1cb4aa4a98a546d0bac5720" contextRef="c20251105to20251105">8-K</ix:nonNumeric></div>

    <div><br/>
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    <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">CURRENT REPORT</div>

    <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934</div>

    <div><br/>
    </div>

    <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Date of Report (Date of earliest event reported): <ix:nonNumeric name="dei:DocumentPeriodEndDate" id="Fact_7e29da0bc3424845bf1a07f233cd9d01" contextRef="c20251105to20251105" format="ixt:date-monthname-day-year-en">November 5, 2025</ix:nonNumeric></div>

    <div><br/>
    </div>

    <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif; font-size: 24pt; font-weight: bold;"><ix:nonNumeric name="dei:EntityRegistrantName" id="Fact_7a61dfea3e2749b0a23c3f2851a73f8f" contextRef="c20251105to20251105">Opus Genetics, Inc.</ix:nonNumeric><br/>
    </div>

    <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">(Exact name of registrant as specified in its charter)</div>

    <div><br/>
    </div>

    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;"><ix:nonNumeric name="dei:EntityIncorporationStateCountryCode" id="Fact_3d059172b2b348d4ba9e8ccd5d8ec4ed" contextRef="c20251105to20251105" format="ixt-sec:stateprovnameen">Delaware</ix:nonNumeric><br/>
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    <td style="width: 30%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;"><ix:nonNumeric name="dei:EntityFileNumber" id="Fact_984eb5fc2fe2429a909e66735b2d65c0" contextRef="c20251105to20251105">001-34079</ix:nonNumeric><br/>
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    <td style="width: 30%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;"><ix:nonNumeric name="dei:EntityTaxIdentificationNumber" id="Fact_ef08e9e9128d4714977dac320a48620d" contextRef="c20251105to20251105">11-3516358</ix:nonNumeric><br/>
            </div>
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    <td style="width: 40%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">(State or other jurisdiction of incorporation)</div>
          </td>

    <td style="width: 30%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">(Commission File Number)</div>
          </td>

    <td style="width: 30%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">(IRS Employer Identification No.)</div>
          </td>

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    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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    <td style="width: 80%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;"><span style="-sec-ix-hidden:Fact_f8475e046b754fbe8609829d45ed08e3">8 Davis Drive</span>,
              <span style="-sec-ix-hidden:Fact_c49d63472d7a4430adcc3b1f5a58ade1">Suite 220</span></div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;"><span style="-sec-ix-hidden:Fact_d19f37dbf6b247b1a1c11bf2e1122146">Durham</span>,
              <span style="-sec-ix-hidden:Fact_8d272a45290044568623f0746aa1a405">NC</span></div>
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    <td style="width: 20%; vertical-align: bottom;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;"><ix:nonNumeric name="dei:EntityAddressPostalZipCode" id="Fact_2ccfb53d1da94be6bc5d157bea4ec132" contextRef="c20251105to20251105">27713</ix:nonNumeric><br/>
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    <td style="width: 80%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">(Address of principal executive offices)</div>
          </td>

    <td style="width: 20%; vertical-align: top;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">(Zip Code)</div>
          </td>

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    <div><br/>
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    <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">(<ix:nonNumeric name="dei:CityAreaCode" id="Fact_62ed3a2681bf4d46978c3b06f121b186" contextRef="c20251105to20251105">248</ix:nonNumeric>) <span style="-sec-ix-hidden:Fact_c1c1ad3ebf0a4bfd85aff24a4501b08a">957-9024</span></div>

    <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">(Registrant&#8217;s telephone number, including area code)</div>

    <div><br/>
    </div>

    <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">N/A</div>

    <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">(Former name or former address, if changed since last report)</div>

    <div><br/>
    </div>

    <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any
      of the following provisions:</div>

    <div><br/>
    </div>

    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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    <td style="width: 2%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"><ix:nonNumeric name="dei:WrittenCommunications" id="Fact_a182625ea1204a558d9beed72b1bce40" contextRef="c20251105to20251105" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric><br/>
            </div>
          </td>

    <td style="width: 98%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</div>
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    </div>

    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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    <td style="width: 2%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"><ix:nonNumeric name="dei:SolicitingMaterial" id="Fact_6fa30b01756b47908b68acee0422d4ba" contextRef="c20251105to20251105" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric><br/>
            </div>
          </td>

    <td style="width: 98%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)</div>
          </td>

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    </div>

    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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    <td style="width: 1.89%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"><ix:nonNumeric name="dei:PreCommencementTenderOffer" id="Fact_7e94012d124e4ef09aa28b4eac30aae5" contextRef="c20251105to20251105" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric><br/>
            </div>
          </td>

    <td style="width: 98.11%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))</div>
          </td>

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    </div>

    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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    <td style="width: 1.9%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"><ix:nonNumeric name="dei:PreCommencementIssuerTenderOffer" id="Fact_ab2bf2f0da7249e8bf2de4d75f3a8be2" contextRef="c20251105to20251105" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric><br/>
            </div>
          </td>

    <td style="width: 98.1%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))</div>
          </td>

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    <div><br/>
    </div>

    <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Securities registered pursuant to Section 12(b) of the Act:</div>

    <div><br/>
    </div>

    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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    <td style="width: 40.02%; vertical-align: top; border-left: #000000 2px solid; border-right: #000000 2px solid; border-top: #000000 2px solid; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Title of each class</div>
          </td>

    <td style="width: 20%; vertical-align: top; border-width: 2px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Trading Symbol(s)</div>
          </td>

    <td style="width: 40%; vertical-align: top; border-width: 2px; border-style: solid; border-color: rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Name of each exchange on which registered</div>
          </td>

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    <td style="width: 40.02%; vertical-align: top; border-left: #000000 2px solid; border-right: #000000 2px solid; border-bottom: #000000 2px solid;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"><ix:nonNumeric name="dei:Security12bTitle" id="Fact_f6222c7167a94afe88d8e764f78b871b" contextRef="c20251105to20251105">Common Stock, $0.0001 par value per share</ix:nonNumeric><br/>
            </div>
          </td>

    <td style="width: 20%; vertical-align: top; border-left: 2px solid rgb(0, 0, 0); border-right: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"><ix:nonNumeric name="dei:TradingSymbol" id="Fact_3b358f719cab4ec5a2f98d2e761b03a9" contextRef="c20251105to20251105">IRD</ix:nonNumeric><br/>
            </div>
          </td>

    <td style="width: 40%; vertical-align: top; border-left: 2px solid rgb(0, 0, 0); border-right: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"><span style="-sec-ix-hidden:Fact_9b657669a7f44423b2982d0f95493c22">The Nasdaq Stock Market LLC</span><br/>
            </div>
          </td>

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</table>
    <div><br/>
    </div>

    <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (&#167;230.405 of
      this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (&#167;240.12b-2 of this chapter). Emerging growth company <ix:nonNumeric name="dei:EntityEmergingGrowthCompany" id="Fact_ce2596ff38d9412c8c51afa6bea4fb31" contextRef="c20251105to20251105" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric></div>

    <div><br/>
    </div>

    <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying
      with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. &#9744; </div>

    <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"> <br/>
    </div>

    <div>
      <hr style="border: none; border-bottom: 4px solid black; border-top: 1px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;"/></div>

    <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div class="BRPFPageBreak" style="page-break-after: always;">
        <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"/></div>

    </div>

    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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    <td colspan="2" style="vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Item 1.01</div>
          </td>

    <td style="width: 90%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Entry into a Material Definitive Agreement.</div>
          </td>

  </tr>


</table>
    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-style: italic;"> <br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-style: italic;">Registered Direct Offering</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">On November 5, 2025, Opus Genetics, Inc. (the &#8220;Company&#8221;) entered into a securities purchase agreement (the &#8220;<span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><span style="text-decoration: underline;">Purchase Agreement</span></span>&#8221;) with certain affiliates of Perceptive Advisors LLC, Nantahala Capital Management, LLC and Balyasny Asset Management L.P. (collectively, the &#8220;<span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><span style="text-decoration: underline;">Purchasers</span></span>&#8221;), pursuant to which the Company agreed to issue and sell, in a registered direct offering (the &#8220;<span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><span style="text-decoration: underline;">Offering</span></span>&#8221;),







      an aggregate of (i) 3,827,751 shares (the &#8220;<span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><span style="text-decoration: underline;">Shares</span></span>&#8221;) of the Company&#8217;s common stock, par value $0.0001 per share ( &#8220;<span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><span style="text-decoration: underline;">Common Stock</span></span>&#8221;), to the Purchasers and (ii) pre-funded warrants to purchase 7,177,033 shares of Common Stock (the &#8220;<span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><span style="text-decoration: underline;">Pre-Funded







          Warrants</span></span>&#8221; and, together with the Shares, the &#8220;<span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><span style="text-decoration: underline;">Securities</span></span>&#8221;) to certain of the Purchasers who have elected to receive them in lieu of additional
      shares of Common Stock The offering price of each Share is $2.09 per share and the offering price of each Pre-Funded Warrant is $2.0899, which is equal to the offering price per Share, minus $0.0001, the exercise price of the Pre-Funded Warrant. The
      gross proceeds to the Company from the Offering are expected to be approximately $23.0 million, before deducting offering expenses payable by the Company. The Company will receive nominal proceeds, if any, from the exercise of the Pre-Funded
      Warrants.</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">The Offering is expected to close on or about November 7, 2025, subject to the satisfaction of customary closing conditions. The Company currently plans to
      use the net proceeds from the Offering from this offering to advance its LCA5 and BEST-1 gene therapy clinical programs, as well as for working capital and general corporate purposes.</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">The Securities are being offered directly to the Purchasers without a placement agent or underwriter, and the Company is not paying underwriting discounts
      or commissions in connection with the Offering.</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">The Offering (including the shares of Common Stock issuable from time to time upon exercise of the Pre-Funded Warrants) was made pursuant to the Company&#8217;s
      Registration Statement on Form S-3 (File No. 333-276462) filed with the Securities and Exchange Commission on January 10, 2024, including the prospectus dated January 23, 2024 contained therein, as the same has been supplemented.</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">The Purchase Agreement contains customary representations, warranties and covenants by the Company and the Purchasers, customary closing conditions and
      other terms and conditions typical for transactions of this type. The Purchase Agreement also includes indemnification obligations of the Company, including with respect to liabilities arising under the Securities Act of 1933, as amended (the &#8220;<span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><span style="text-decoration: underline;">Securities Act</span></span>&#8221;), as well as customary termination provisions. The representations, warranties and covenants contained in the Purchase Agreement were made only for
      purposes of that agreement and as of specific dates, were made solely for the benefit of the parties to the agreement and may be subject to limitations agreed upon by the contracting parties.</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">The foregoing description of the Purchase Agreement does not purport to be complete and is qualified in its entirety by the full text of the form of
      Purchase Agreement, a copy of which is filed as Exhibit 10.1 to this Current Report on Form 8-K and incorporated by reference herein.</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-style: italic;">Terms of the Pre-Funded Warrants</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">The Pre-Funded Warrants were issued pursuant to a pre-funded common stock purchase warrant (the &#8220;<span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><span style="text-decoration: underline;">Form of Pre-Funded Warrant</span></span>&#8221;). Each Pre-Funded Warrant offered has an exercise price of $0.0001 per share of Common Stock, is immediately exercisable and is exercisable at any time until exercised in full. The
      exercise prices and numbers of shares of Common Stock issuable upon exercise are subject to appropriate adjustment in the event of stock dividends, stock splits, reorganizations or similar events affecting the Common Stock.</div>

    <div><br/>
    </div>

    <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div class="BRPFPageBreak" style="page-break-after: always;">
        <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"/></div>

    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">A holder may not exercise a Pre-Funded Warrant if, after giving effect to such exercise, the holder (together with its affiliates) would beneficially own
      (as determined in accordance with the terms of the Pre-Funded Warrants) more than 4.99% (or, at the election of the holder, 9.99%) of the outstanding Common Stock immediately after giving effect to the exercise.</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">In the event of a &#8220;fundamental transaction,&#8221; as defined in the Form of Pre-Funded Warrant, the holders of the Pre-Funded Warrants will be entitled to
      receive upon exercise of the Pre-Funded Warrants the kind and amount of securities, cash or other property that the holders would have received had they exercised the Pre-Funded Warrants immediately prior to such fundamental transaction.</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">The Form of Pre-Funded Warrant is filed as Exhibit 4.1 hereto and is incorporated by reference into this Current Report on Form 8-K, and the foregoing
      description of the terms of the Pre-Funded Warrants is qualified in its entirety by reference to the full text of such exhibit.</div>

    <div><br/></div>

    <div style="text-align: left;">
<div><span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;"> </span></div>

      <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; color: #000000; width: 100%; border-spacing: 0;">


  <tr>

    <td style="width: 10%;"><span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Item&#8201;8.01</span></td>

    <td style="width: 90%;">
              <div style="text-align: left;"><span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Other Events.</span></div>
            </td>

  </tr>


</table>
    </div>

    <div style="text-align: left;"><br/>
    </div>

    <div style="text-align: left; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">A copy of the opinion of Sidley Austin LLP, counsel to the Company, relating to the securities issued in the Offering is attached as Exhibit 5.1 to this
      report.</div>

    <div><br/>
    </div>

    <div><br/></div>

    <div><br/>
    </div>

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        <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"/></div>

    </div>

    <div><br/></div>

    <div><br/>
    </div>

    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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    <td style="width: 10%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Item&#8201;9.01</div>
          </td>

    <td style="width: 90%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Financial Statements and Exhibits.</div>
          </td>

  </tr>


</table>
    <div style="text-align: left;"><span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"> </span><br/>
    </div>

    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000; border-spacing: 0;">


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    <td style="width: 8%; vertical-align: bottom; white-space: nowrap;">
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Exhibit</div>
            <div style="text-align: center; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">No.</div>
          </td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 91%; vertical-align: bottom; white-space: nowrap;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Description</div>
          </td>

  </tr>

  <tr>

    <td style="width: 8%; vertical-align: middle;">&#160;</td>

    <td colspan="2" style="vertical-align: middle;">&#160;</td>

  </tr>

  <tr>

    <td style="width: 8%; vertical-align: top; white-space: nowrap;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif; font-size: 10pt;"><a href="ny20058362x2_ex4-1.htm">4.1</a></div>
          </td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 91%; vertical-align: top;">
            <div style="text-align: left; font-family: 'Times New Roman',Times,serif; font-size: 10pt;">Form of Pre-Funded Warrant.</div>
          </td>

  </tr>

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    <td style="width: 8%; vertical-align: middle; text-align: center;">&#160;</td>

    <td colspan="2" style="vertical-align: middle;">&#160;</td>

  </tr>

  <tr>

    <td style="width: 8%; vertical-align: top; white-space: nowrap;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif; font-size: 10pt;"><a href="ny20058362x2_ex5-1.htm">5.1</a></div>
          </td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 91%; vertical-align: top;">
            <div style="text-align: left; font-family: 'Times New Roman',Times,serif; font-size: 10pt;">Opinion of Sidley Austin LLP.</div>
          </td>

  </tr>

  <tr>

    <td style="width: 8%; vertical-align: middle; text-align: center;">&#160;</td>

    <td colspan="2" style="vertical-align: middle;">&#160;</td>

  </tr>

  <tr>

    <td style="width: 8%; vertical-align: top; white-space: nowrap;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif; font-size: 10pt;"><a href="ny20058362x2_ex10-1.htm">10.1</a></div>
          </td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 91%; vertical-align: top;">
            <div style="text-align: left; font-family: 'Times New Roman',Times,serif; font-size: 10pt;">Securities Purchase Agreement, by and among Opus Genetics, Inc. and the Purchasers, dated November 5, 2025.</div>
          </td>

  </tr>

  <tr>

    <td style="width: 8%; vertical-align: middle; text-align: center;">&#160;</td>

    <td colspan="2" style="vertical-align: middle;">&#160;</td>

  </tr>

  <tr>

    <td style="width: 8%; vertical-align: top; white-space: nowrap;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif; font-size: 10pt;"><a href="ny20058362x2_ex5-1.htm">23.1</a></div>
          </td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 91%; vertical-align: top;">
            <div style="text-align: left; font-family: 'Times New Roman',Times,serif; font-size: 10pt;">Consent of Sidley Austin LLP (contained in Exhibit 5.1).</div>
          </td>

  </tr>

  <tr>

    <td style="width: 8%; vertical-align: top; text-align: center; white-space: nowrap;">&#160;</td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 91%; vertical-align: top;">&#160;</td>

  </tr>

  <tr>

    <td style="width: 8%; vertical-align: top; white-space: nowrap;">
            <div style="text-align: center; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif; font-size: 10pt;">104</div>
          </td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 91%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Cover Page Interactive Data File (embedded within the Inline XBRL document).</div>
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  </tr>


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    <div><br/>
    </div>

    <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">Forward-Looking Statements</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"><span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; color: #000000;">This Current Report on Form 8-K contains forward-looking
        statements within the meaning of the Private Securities Litigation Reform Act of 1995. The Company intends such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in Section 27A of the
        Securities Act and Section 21E of the Exchange Act. All statements contained in this Current Report on Form 8-K that do not relate to matters of historical fact should be considered forward-looking statements, including, without limitation, the
        intended use of proceeds of the Offering and other statements relating to the Offering. In some cases, you can identify forward-looking statements by terms such as &#8220;aim,&#8221; &#8220;anticipate,&#8221; &#8220;approach,&#8221; &#8220;believe,&#8221; &#8220;contemplate,&#8221; &#8220;could,&#8221; &#8220;designed&#8221;,
        &#8220;estimate,&#8221; &#8220;expect,&#8221; &#8220;goal,&#8221; &#8220;intend,&#8221; &#8220;look,&#8221; &#8220;may,&#8221; &#8220;mission,&#8221; &#8220;plan,&#8221; &#8220;possible,&#8221; &#8220;potential,&#8221; &#8220;predict,&#8221; &#8220;project,&#8221; &#8220;pursue,&#8221; &#8220;should,&#8221;, &#8220;strive&#8221;, &#8220;target,&#8221; &#8220;will,&#8221; &#8220;would,&#8221; or the negative thereof and similar words and expressions.
        Forward-looking statements are based on management&#8217;s current expectations, beliefs and assumptions and on information currently available to the Company. Such statements are neither promises nor guarantees, and involve a number of known and unknown
        risks, uncertainties and assumptions. Actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including, without limitation, risks and uncertainties associated with the
        consummation of the Offering, uncertainties related to market conditions, the satisfaction of customary closing conditions, the completion of the Offering on the anticipated terms or at all, general economic conditions and other risks identified
        from time to time in the reports the Company files with the SEC, including the Annual Report on Form 10-K for the fiscal year ended December 31, 2024, as such factors may be updated from time to time in its other filings with the SEC, accessible on
        the SEC&#8217;s website at </span><span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-style: italic;">www.sec.gov</span><span style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; color: #000000;">. The
        forward-looking statements in this Current Report on Form 8-K speak only as of the date of this Current Report on Form 8-K, and the Company undertakes no obligation to update or revise any of the statements. The Company&#8217;s business is subject to
        substantial risks and uncertainties, including those referenced above. Investors, potential investors, and others should give careful consideration to these risks and uncertainties.</span></div>

    <div><br/>
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    <div style="text-align: center; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">SIGNATURES</div>

    <div><br/>
    </div>

    <div style="text-align: justify; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the
      undersigned hereunto duly authorized.</div>

    <div><br/>
    </div>

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    <td style="width: 49%; vertical-align: bottom;">&#160;</td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td colspan="3" style="vertical-align: bottom;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; font-weight: bold;">OPUS GENETICS, INC.</div>
          </td>

  </tr>

  <tr>

    <td colspan="5" style="vertical-align: middle;">&#160;</td>

  </tr>

  <tr>

    <td style="width: 49%; vertical-align: bottom;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Date: November 6, 2025</div>
          </td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 6%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">By:</div>
          </td>

    <td style="width: 4%; vertical-align: bottom;">&#160;</td>

    <td style="width: 40%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div>
              <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">/s/ Dr. George Magrath</div>
            </div>
          </td>

  </tr>

  <tr>

    <td style="width: 49%; vertical-align: bottom;">&#160;</td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 6%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Name:</div>
          </td>

    <td style="width: 4%; vertical-align: bottom;">&#160;</td>

    <td style="width: 40%; vertical-align: bottom;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Dr. George Magrath</div>
          </td>

  </tr>

  <tr>

    <td style="width: 49%; vertical-align: bottom;">&#160;</td>

    <td style="width: 1%; vertical-align: bottom;">&#160;</td>

    <td style="width: 6%; vertical-align: top;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Title:</div>
          </td>

    <td style="width: 4%; vertical-align: bottom;">&#160;</td>

    <td style="width: 40%; vertical-align: bottom;">
            <div style="text-align: left; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">Chief Executive Officer</div>
          </td>

  </tr>


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<TYPE>EX-4.1
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<FILENAME>ny20058362x2_ex4-1.htm
<DESCRIPTION>EXHIBIT 4.1
<TEXT>
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    <div style="text-align: right;"><font style="font-weight: bold;">Exhibit 4.1</font><br>
    </div>
    <div>
      <div>&#160;</div>
      <div style="text-align: center; font-weight: bold;">PRE-FUNDED COMMON STOCK PURCHASE WARRANT</div>
      <div><br>
      </div>
      <div style="text-align: center; font-weight: bold;">OPUS GENETICS, INC</div>
      <div>&#160;</div>
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              <div>Warrant Shares:<br>
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            <td style="width: 10%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">&#160;</td>
            <td style="width: 47%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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              <div>Initial Exercise Date: November 7, 2025</div>
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      <div style="text-align: justify; text-indent: 72pt;">THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the &#8220;<u>Warrant</u>&#8221;) certifies that, for value received, <font style="font-variant: small-caps;">______________ </font>or its assigns (the &#8220;<u>Holder</u>&#8221;)

        is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the &#8220;<u>Initial Exercise Date</u>&#8221;) and <a name="z_DV_C1"></a>until this Warrant is exercised
        in full<a name="z_DV_M6"></a> (the &#8220;<u>Termination Date</u>&#8221;) but not thereafter, to subscribe for and purchase from Opus Genetics, Inc., a Delaware corporation (the &#8220;<u>Company</u>&#8221;), up to <font style="font-variant: small-caps;">______________</font>shares

        (as subject to adjustment hereunder, the &#8220;<u>Warrant Shares</u>&#8221;) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt;"><u>Section 1</u>.&#160;&#160;&#160;&#160; &#160; &#160; <u>Definitions</u>.&#160; In addition to the terms defined elsewhere in this Warrant, the following terms have the meanings indicated in this Section 1:</div>
      <div>&#160;</div>
      <div style="text-align: justify; margin-left: 36pt; text-indent: 36pt;">&#8220;<u>Affiliate</u>&#8221; means any Person that, directly or indirectly through one or more intermediaries, controls or is controlled by or is under common control with a Person, as
        such terms are used in and construed under Rule 405 under the Securities Act.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Bid Price</u>&#8221; means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed or quoted on a Trading
        Market, the bid price of the Common Stock for the time in question (or the nearest preceding date) on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg L.P. (based on a Trading Day from 9:30 a.m. (New
        York City time) to 4:02 p.m. (New York City time)), (b)&#160; if OTCQB or OTCQX is not a Trading Market, the volume weighted average price of the Common Stock for such date (or the nearest preceding date) on OTCQB or OTCQX as applicable, (c) if the
        Common Stock is not then listed or quoted for trading on OTCQB or OTCQX and if prices for the Common Stock are then reported on the Pink Open Market (or a similar organization or agency succeeding to its functions of reporting prices), the most
        recent bid price per share of the Common Stock so reported, or (d) in all other cases, the fair market value of a share of Common Stock as determined by an independent appraiser selected in good faith by the Holders of a majority in interest of the
        Warrants then outstanding and reasonably acceptable to the Company, the fees and expenses of which shall be paid by the Company.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Board of Directors</u>&#8221; means the board of directors of the Company.</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">1</font></div>
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Business Day</u>&#8221; means any day other than Saturday, Sunday or other day on which commercial banks in The City of New York are authorized or required by law to remain closed;
        <u>provided</u>, <u>however</u>, for clarification, commercial banks shall not be deemed to be authorized or required by law to remain closed due to &#8220;stay at home&#8221;, &#8220;shelter-in-place&#8221;, &#8220;non-essential employee&#8221;&#160; or any other similar orders or
        restrictions or the closure of any physical branch locations at the direction of any governmental authority so long as the electronic funds transfer systems (including for wire transfers) of commercial banks in The City of New York generally are
        open for use by customers on such day.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Commission</u>&#8221; means the United States Securities and Exchange Commission.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Common Stock</u>&#8221; means the common stock of the Company, par value $0.0001 per share, and any other class of securities into which such securities may hereafter be
        reclassified or changed.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Common Stock Equivalents</u>&#8221; means any securities of the Company or the Subsidiaries which would entitle the holder thereof to acquire at any time Common Stock, including,
        without limitation, any debt, preferred stock, right, option, warrant or other instrument that is at any time convertible into or exercisable or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Exchange Act</u>&#8221; means the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated thereunder.</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Person</u>&#8221; means an individual or corporation, partnership, trust, incorporated or unincorporated association, joint venture, limited liability company, joint stock company,
        government (or an agency or subdivision thereof) or other entity of any kind.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Purchase Agreement</u>&#8221; means the securities purchase agreement, dated as of November 5, 2025, among the Company and the Purchasers named therein, as amended, modified or
        supplemented from time to time in accordance with its terms.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Registration Statement</u>&#8221; means the Company&#8217;s registration statement on Form S-3 (File No. 333-276462).</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Securities Act</u>&#8221; means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Subsidiary</u>&#8221; means any subsidiary of the Company and shall, where applicable, also include any direct or indirect subsidiary of the Company formed or acquired after the
        date hereof.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Trading Day</u>&#8221; means a day on which the Common Stock is traded on a Trading Market.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Trading Market</u>&#8221; means any of the following markets or exchanges on which the Common Stock is listed or quoted for trading on the date in question: the NYSE American, the
        Nasdaq Capital Market, the Nasdaq Global Market, the Nasdaq Global Select Market, the New York Stock Exchange (or any successors to any of the foregoing).</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">2</font></div>
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Transfer Agent</u>&#8221; means Equiniti Trust Company, LLC, the current transfer agent of the Company, with a mailing address of 48 Wall Street, 22nd Floor, New York, NY 10005 and
        an email address of ReorgWarrants@equiniti.com, and any successor transfer agent of the Company.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>VWAP</u>&#8221; means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed or quoted on a Trading Market,
        the daily volume weighted average price of the Common Stock for such date (or the nearest preceding date) on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg L.P. (based on a Trading Day from 9:30 a.m.
        (New York City time) to 4:02 p.m. (New York City time)), (b)&#160; if OTCQB or OTCQX is not a Trading Market, the volume weighted average price of the Common Stock for such date (or the nearest preceding date) on OTCQB or OTCQX as applicable, (c) if the
        Common Stock is not then listed or quoted for trading on OTCQB or OTCQX and if prices for the Common Stock are then reported on the Pink Open Market (or a similar organization or agency succeeding to its functions of reporting prices), the most
        recent bid price per share of the Common Stock so reported, or (d) in all other cases, the fair market value of a share of Common Stock as determined by an independent appraiser selected in good faith by the holders of a majority in interest of the
        Warrants then outstanding and reasonably acceptable to the Company, the fees and expenses of which shall be paid by the Company.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">&#8220;<u>Warrants</u>&#8221; means this Warrant and other Pre-Funded Common Stock purchase warrants issued by the Company pursuant to the Registration Statement.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt;"><u>Section 2</u>.&#160;&#160;&#160;&#160;&#160; &#160; &#160; <u>Exercise</u>.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">a)&#160;&#160;&#160; &#160; &#160; <u>Exercise of Warrant</u>.&#160; Exercise of the purchase rights represented by this Warrant may be made, in whole or in part, at any time or times on or after the Initial
        Exercise Date and on or before the Termination Date by delivery to the Company of a duly executed PDF copy submitted by e-mail (or e-mail attachment) of the Notice of Exercise in the form annexed hereto (the &#8220;<u>Notice of Exercise</u>&#8221;). Within the
        earlier of (i) one (1) Trading Day and (ii) the number of Trading Days comprising the Standard Settlement Period (as defined in Section 2(d)(i) herein) following the date of exercise as aforesaid, the Holder shall deliver the aggregate Exercise
        Price for the shares specified in the applicable Notice of Exercise by wire transfer or cashier&#8217;s check drawn on a United States bank unless the cashless exercise procedure specified in Section 2(c) below is specified in the applicable Notice of
        Exercise. No ink-original Notice of Exercise shall be required, nor shall any medallion guarantee (or other type of guarantee or notarization) of any Notice of Exercise be required.&#160; Notwithstanding anything herein to the contrary, the Holder shall
        not be required to physically surrender this Warrant to the Company until the Holder has purchased all of the Warrant Shares available hereunder and the Warrant has been exercised in full, in which case, the Holder shall surrender this Warrant to
        the Company for cancellation within three (3) Trading Days of the date on which the final Notice of Exercise is delivered to the Company. Partial exercises of this Warrant resulting in purchases of a portion of the total number of Warrant Shares
        available hereunder shall have the effect of lowering the outstanding number of Warrant Shares purchasable hereunder in an amount equal to the applicable number of Warrant Shares purchased.&#160; The Holder and the Company shall maintain records showing
        the number of Warrant Shares purchased and the date of such purchases. The Company shall deliver any objection to any Notice of Exercise on the Trading Day of receipt of such notice.&#160; <font style="font-weight: bold;">The Holder and any assignee,
          by acceptance of this Warrant, acknowledge and agree that, by reason of the provisions of this paragraph, following the purchase of a portion of the Warrant Shares hereunder, the number of Warrant Shares available for purchase hereunder at any
          given time may be less than the amount stated on the face hereof.</font></div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">3</font></div>
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">b)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Exercise Price</u>.&#160; The aggregate exercise price of this Warrant, except for a nominal exercise price of $0.0001 per Warrant Share, was pre-funded to the Company
        on or prior to the Initial Exercise Date and, consequently, no additional consideration (other than the nominal exercise price of $0.0001 per Warrant Share) shall be required to be paid by the Holder to any Person to effect any exercise of this
        Warrant.&#160; The Holder shall not be entitled to the return or refund of all, or any portion, of such pre-paid aggregate exercise price under any circumstance or for any reason whatsoever, including in the event this Warrant shall not have been
        exercised prior to the Termination Date. The remaining unpaid exercise price per share of Common Stock under this Warrant shall be $0.0001, subject to adjustment hereunder (the &#8220;<u>Exercise Price</u>&#8221;).</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">c)&#160;&#160;&#160;&#160;&#160;&#160; <u>Cashless Exercise</u>. This Warrant may also be exercised, in whole or in part, at such time by means of a &#8220;cashless exercise&#8221; in which the Holder shall be entitled
        to receive a number of Warrant Shares equal to the quotient obtained by dividing [(A-B) (X)] by (A), where:</div>
      <div>&#160;</div>
      <table cellspacing="0" cellpadding="0" id="z75ba103232b44c2ca74d1f98e85546a9" class="DSPFListTable" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

          <tr>
            <td style="width: 90pt;">&#160;</td>
            <td style="width: 15pt; vertical-align: top;">(A)</td>
            <td style="width: auto; vertical-align: top; text-align: justify;">
              <div>= as applicable: (i) the VWAP on the Trading Day immediately preceding the date of the applicable Notice of Exercise if such Notice of Exercise is (1) delivered pursuant to Section 2(a) hereof on a day that is not a Trading Day or (2)
                delivered pursuant to Section 2(a) hereof on a Trading Day prior to the opening of &#8220;regular trading hours&#8221; (as defined in Rule 600(b) of Regulation NMS promulgated under the federal securities laws) on such Trading Day, (ii) the highest Bid
                Price of the Common Stock on the principal Trading Market as reported by Bloomberg L.P. (&#8220;<u>Bloomberg</u>&#8221;) within two (2) hours of the time of the Holder&#8217;s delivery of the Notice of Exercise pursuant to Section 2(a) hereof if such Notice
                of Exercise is delivered during &#8220;regular trading hours,&#8221; or within two (2) hours after the close of &#8220;regular trading hours,&#8221; on a Trading Day or (iii) the VWAP on the date of the applicable Notice of Exercise if the date of such Notice of
                Exercise is a Trading Day and such Notice of Exercise is delivered pursuant to Section 2(a) hereof after two (2) hours following the close of &#8220;regular trading hours&#8221; on such Trading Day;</div>
            </td>
          </tr>

      </table>
      <div><br>
      </div>
      <div>
        <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%;" id="z9f06b190309f451b88ade385b573d392" class="DSPFListTable">

            <tr style="vertical-align: top;">
              <td style="width: 90pt;">&#160;</td>
              <td style="text-align: right; vertical-align: top; width: 15pt;">
                <div style="text-align: justify;">(B)</div>
              </td>
              <td style="text-align: left; vertical-align: top; width: auto;">
                <div style="text-align: justify;">= the Exercise Price of this Warrant, as adjusted hereunder; and</div>
              </td>
            </tr>

        </table>
      </div>
      <div><br>
      </div>
      <div>
        <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%;" id="zb9c53754217b42dd8ecacc0a1b77f10c" class="DSPFListTable">

            <tr style="vertical-align: top;">
              <td style="width: 90pt;">&#160;</td>
              <td style="text-align: right; vertical-align: top; width: 15pt;">
                <div style="text-align: justify;">(X)</div>
              </td>
              <td style="text-align: left; vertical-align: top; width: auto;">
                <div style="text-align: justify;">= the number of Warrant Shares that would be issuable upon exercise of this Warrant in accordance with the terms of this Warrant if such exercise were by means of a cash exercise rather than a cashless
                  exercise.</div>
              </td>
            </tr>

        </table>
      </div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">If Warrant Shares are issued in such a cashless exercise, the parties acknowledge and agree that in accordance with Section 3(a)(9) of the Securities Act, the Warrant Shares
        shall take on the registered characteristics of the Warrants being exercised.&#160; The Company agrees not to take any position contrary to this Section 2(c).</div>
      <div><br>
        <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
          <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">4</font></div>
          <div style="page-break-after: always;" class="BRPFPageBreak">
            <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
        </div>
      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;"> d)&#160;&#160;&#160;&#160;&#160;&#160; <font style="font-size: 10pt;"><u>Mechanics of Exercise</u></font>.<br>
      </div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 108pt;">&#160;i.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="font-size: 10pt;"><u>Delivery of Warrant Shares Upon Exercise</u>.&#160; The Company shall cause the Warrant Shares purchased hereunder to be transmitted
          by the Transfer Agent to the Holder by crediting the account of the Holder&#8217;s or its designee&#8217;s balance account with The Depository Trust Company through its Deposit or Withdrawal at Custodian system (&#8220;<u>DWAC</u>&#8221;) if the Company is then a
          participant in such system and either (A) there is an effective registration statement permitting the issuance of the Warrant Shares to or resale of the Warrant Shares by Holder or (B) this Warrant is being exercised via cashless exercise, and
          otherwise by physical delivery of a certificate, registered in the Company&#8217;s share register in the name of the Holder or its designee, for the number of Warrant Shares to which the Holder is entitled pursuant to such exercise to the address
          specified by the Holder in the Notice of Exercise by the date that is the earlier of (i) one (1) Trading Day after the delivery to the Company of the Notice of Exercise and (ii) the number of Trading Days comprising the Standard Settlement Period
          after the delivery to the Company of the Notice of Exercise (such date, the &#8220;<u>Warrant Share Delivery Date</u>&#8221;).&#160;&#160; Upon delivery of the Notice of Exercise, the Holder shall be deemed for all corporate purposes to have become the holder of
          record of the Warrant Shares with respect to which this Warrant has been exercised, irrespective of the date of delivery of the Warrant Shares, provided that payment of the aggregate Exercise Price (other than in the case of a cashless exercise)
          is received within the earlier of (i) one (1) Trading Day and (ii) the number of Trading Days comprising the Standard Settlement Period following delivery of the Notice of Exercise.&#160; If the Company fails for any reason to deliver to the Holder
          the Warrant Shares subject to a Notice of Exercise by the Warrant Share Delivery Date, the Company shall pay to the Holder, in cash, as liquidated damages and not as a penalty, for each $1,000 of Warrant Shares subject to such exercise (based on
          the VWAP of the Common Stock on the date of the applicable Notice of Exercise), $10 per Trading Day (increasing to $20 per Trading Day on the third Trading Day after the Warrant Share Delivery Date) for each Trading Day after such Warrant Share
          Delivery Date until such Warrant Shares are delivered or Holder rescinds such exercise. The Company agrees to maintain a transfer agent that is a participant in the FAST program so long as this Warrant remains outstanding and exercisable.&#160; As
          used herein, &#8220;<u>Standard Settlement Period</u>&#8221; means the standard settlement period, expressed in a number of Trading Days, on the Company&#8217;s primary Trading Market with respect to the Common Stock as in effect on the date of delivery of the
          Notice of Exercise. Notwithstanding the foregoing, with respect to any Notice(s) of Exercise delivered on or prior to 12:00 p.m. (New York City time) on the Initial Exercise Date, which may be delivered at any time after the time of execution of
          the Purchase Agreement, the Company agrees to deliver the Warrant Shares subject to such notice(s) by 4:00 p.m. (New York City time) on the Initial Exercise Date and the Initial Exercise Date shall be the Warrant Share Delivery Date for purposes
          hereunder, provided that payment of the aggregate Exercise Price (other than in the case of a cashless exercise) is received by such Warrant Share Delivery Date.</font></div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">5</font></div>
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 108pt;">ii.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<u>Delivery of New Warrants Upon Exercise</u>.&#160; If this Warrant shall have been exercised in part, the Company shall, at the request of a Holder and upon surrender
        of this Warrant certificate, at the time of delivery of the Warrant Shares, deliver to the Holder a new Warrant evidencing the rights of the Holder to purchase the unpurchased Warrant Shares called for by this Warrant, which new Warrant shall in
        all other respects be identical with this Warrant.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 108pt;">iii.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<u>Rescission Rights</u>.&#160; If the Company fails to cause the Transfer Agent to transmit to the Holder the Warrant Shares pursuant to Section 2(d)(i) by the Warrant
        Share Delivery Date, then the Holder will have the right to rescind such exercise.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 108pt;">iv.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<u>Compensation for Buy-In on Failure to Timely Deliver Warrant Shares Upon Exercise</u>.&#160; In addition to any other rights available to the Holder, if the Company
        fails to cause the Transfer Agent to transmit to the Holder the Warrant Shares in accordance with the provisions of Section 2(d)(i) above pursuant to an exercise on or before the Warrant Share Delivery Date, and if after such date the Holder is
        required by its broker to purchase (in an open market transaction or otherwise) or the Holder&#8217;s brokerage firm otherwise purchases, shares of Common Stock to deliver in satisfaction of a sale by the Holder of the Warrant Shares which the Holder
        anticipated receiving upon such exercise (a &#8220;<u>Buy-In</u>&#8221;), then the Company shall (A) pay in cash to the Holder the amount, if any, by which (x) the Holder&#8217;s total purchase price (including brokerage commissions, if any) for the shares of Common
        Stock so purchased exceeds (y) the amount obtained by multiplying (1) the number of Warrant Shares that the Company was required to deliver to the Holder in connection with the exercise at issue times (2) the price at which the sell order giving
        rise to such purchase obligation was executed, and (B) at the option of the Holder, either reinstate the portion of the Warrant and equivalent number of Warrant Shares for which such exercise was not honored (in which case such exercise shall be
        deemed rescinded) or deliver to the Holder the number of shares of Common Stock that would have been issued had the Company timely complied with its exercise and delivery obligations hereunder.&#160; For example, if the Holder purchases Common Stock
        having a total purchase price of $11,000 to cover a Buy-In with respect to an attempted exercise of shares of Common Stock with an aggregate sale price giving rise to such purchase obligation of $10,000, under clause (A) of the immediately
        preceding sentence the Company shall be required to pay the Holder $1,000. The Holder shall provide the Company written notice indicating the amounts payable to the Holder in respect of the Buy-In and, upon request of the Company, evidence of the
        amount of such loss.&#160; Nothing herein shall limit a Holder&#8217;s right to pursue any other remedies available to it hereunder, at law or in equity including, without limitation, a decree of specific performance and/or injunctive relief with respect to
        the Company&#8217;s failure to timely deliver shares of Common Stock upon exercise of the Warrant as required pursuant to the terms hereof.</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">6</font></div>
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 108pt;">v.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<u>No Fractional Shares or Scrip</u>.&#160; No fractional shares or scrip representing fractional shares shall be issued upon the exercise of this Warrant.&#160; As to any
        fraction of a share which the Holder would otherwise be entitled to purchase upon such exercise, the Company shall, at its election, either pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied by
        the Exercise Price or round up to the next whole share.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 108pt;">vi.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<u>Charges, Taxes and Expenses</u>.&#160; Issuance of Warrant Shares shall be made without charge to the Holder for any issue or transfer tax or other incidental expense
        in respect of the issuance of such Warrant Shares, all of which taxes and expenses shall be paid by the Company, and such Warrant Shares shall be issued in the name of the Holder or in such name or names as may be directed by the Holder; <u>provided</u>,
        <u>however</u>, that, in the event that Warrant Shares are to be issued in a name other than the name of the Holder, this Warrant when surrendered for exercise shall be accompanied by the Assignment Form attached hereto duly executed by the Holder
        and the Company may require, as a condition thereto, the payment of a sum sufficient to reimburse it for any transfer tax incidental thereto.&#160; The Company shall pay all Transfer Agent fees required for same-day processing of any Notice of Exercise
        and all fees to the Depository Trust Company (or another established clearing corporation performing similar functions) required for same-day electronic delivery of the Warrant Shares.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 108pt;">vii.&#160;&#160;&#160;&#160;&#160;&#160; <u>Closing of Books</u>.&#160; The Company will not close its stockholder books or records in any manner which prevents the timely exercise of this Warrant, pursuant to
        the terms hereof.</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">7</font></div>
        <div style="page-break-after: always;" class="BRPFPageBreak">
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      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">e)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Holder&#8217;s Exercise Limitations</u>.&#160; The Company shall not effect any exercise of this Warrant, and a Holder shall not have the right to exercise any portion of this
        Warrant, pursuant to Section 2 or otherwise, to the extent that after giving effect to such issuance after exercise as set forth on the applicable Notice of Exercise, the Holder (together with the Holder&#8217;s Affiliates, and any other Persons acting
        as a group together with the Holder or any of the Holder&#8217;s Affiliates (such Persons, &#8220;<u>Attribution Parties</u>&#8221;)), would beneficially own in excess of the Beneficial Ownership Limitation (as defined below).&#160; For purposes of the foregoing
        sentence, the number of shares of Common Stock beneficially owned by the Holder and its Affiliates and Attribution Parties shall include the number of shares of Common Stock issuable upon exercise of this Warrant with respect to which such
        determination is being made, but shall exclude the number of shares of Common Stock which would be issuable upon (i) exercise of the remaining, nonexercised portion of this Warrant beneficially owned by the Holder or any of its Affiliates or
        Attribution Parties and (ii) exercise or conversion of the unexercised or nonconverted portion of any other securities of the Company (including, without limitation, any other&#160; Common Stock Equivalents) subject to a limitation on conversion or
        exercise analogous to the limitation contained herein beneficially owned by the Holder or any of its Affiliates or Attribution Parties.&#160; Except as set forth in the preceding sentence, for purposes of this Section 2(e), beneficial ownership shall be
        calculated in accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder, it being acknowledged by the Holder that the Company is not representing to the Holder that such calculation is in compliance with
        Section 13(d) of the Exchange Act and the Holder is solely responsible for any schedules required to be filed in accordance therewith.&#160;&#160; To the extent that the limitation contained in this Section 2(e) applies, the determination of whether this
        Warrant is exercisable (in relation to other securities owned by the Holder together with any Affiliates and Attribution Parties) and of which portion of this Warrant is exercisable shall be in the sole discretion of the Holder, and the submission
        of a Notice of Exercise shall be deemed to be the Holder&#8217;s determination of whether this Warrant is exercisable (in relation to other securities owned by the Holder together with any Affiliates and Attribution Parties) and of which portion of this
        Warrant is exercisable, in each case subject to the Beneficial Ownership Limitation, and the Company shall have no obligation to verify or confirm the accuracy of such determination.&#160; In addition, a determination as to any group status as
        contemplated above shall be determined in accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder.&#160; For purposes of this Section 2(e), in determining the number of outstanding shares of Common Stock, a
        Holder may rely on the number of outstanding shares of Common Stock as reflected in (A) the Company&#8217;s most recent periodic or annual report filed with the Commission, as the case may be, (B) a more recent public announcement by the Company or (C) a
        more recent written notice by the Company or the Transfer Agent setting forth the number of shares of Common Stock outstanding.&#160; Upon the written or oral request of a Holder, the Company shall within one Trading Day confirm orally and in writing to
        the Holder the number of shares of Common Stock then outstanding.&#160; In any case, the number of outstanding shares of Common Stock shall be determined after giving effect to the conversion or exercise of securities of the Company, including this
        Warrant, by the Holder or its Affiliates or Attribution Parties since the date as of which such number of outstanding shares of Common Stock was reported.&#160; The &#8220;<u>Beneficial Ownership Limitation</u>&#8221; shall be 4.99% (or, upon election by a Holder
        prior to the issuance of any Warrants, 9.99%) of the number of shares of Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock issuable upon exercise of this Warrant.&#160; The Holder, upon notice to the
        Company, may increase or decrease the Beneficial Ownership Limitation provisions of this Section 2(e), provided that the Beneficial Ownership Limitation in no event exceeds 9.99% of the number of shares of the Common Stock outstanding immediately
        after giving effect to the issuance of shares of Common Stock upon exercise of this Warrant held by the Holder and the provisions of this Section 2(e) shall continue to apply.&#160; Any increase in the Beneficial Ownership Limitation will not be
        effective until the 61<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">st</sup> day after such notice is delivered to the Company.&#160; The provisions of this paragraph shall be construed and implemented in a manner otherwise
        than in strict conformity with the terms of this Section 2(e) to correct this paragraph (or any portion hereof) which may be defective or inconsistent with the intended Beneficial Ownership Limitation herein contained or to make changes or
        supplements necessary or desirable to properly give effect to such limitation. The limitations contained in this paragraph shall apply to a successor holder of this Warrant.</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">8</font></div>
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      </div>
      <div style="text-align: justify; text-indent: 36pt;"><u>Section 3</u>.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<u>Certain Adjustments</u>.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">a)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Stock Dividends and Splits</u>. If the Company, at any time while this Warrant is outstanding: (i) pays a stock dividend or otherwise makes a distribution or
        distributions on shares of its Common Stock or any other equity or equity equivalent securities payable in shares of Common Stock (which, for avoidance of doubt, shall not include any shares of Common Stock issued by the Company upon exercise of
        this Warrant), (ii) subdivides outstanding shares of Common Stock into a larger number of shares, (iii) combines (including by way of reverse stock split) outstanding shares of Common Stock into a smaller number of shares, or (iv) issues by
        reclassification of shares of the Common Stock any shares of capital stock of the Company, then in each case the Exercise Price shall be multiplied by a fraction of which the numerator shall be the number of shares of Common Stock (excluding
        treasury shares, if any) outstanding immediately before such event and of which the denominator shall be the number of shares of Common Stock outstanding immediately after such event, and the number of shares issuable upon exercise of this Warrant
        shall be proportionately adjusted such that the aggregate Exercise Price of this Warrant shall remain unchanged.&#160; Any adjustment made pursuant to this Section 3(a) shall become effective immediately after the record date for the determination of
        stockholders entitled to receive such dividend or distribution and shall become effective immediately after the effective date in the case of a subdivision, combination or re&#8209;classification.</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">9</font></div>
        <div style="page-break-after: always;" class="BRPFPageBreak">
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      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">b)&#160;&#160;&#160;&#160;&#160; &#160; <u>Subsequent Rights Offerings</u>.&#160; <font style="color: rgb(0, 0, 0);">In addition to any adjustments pursuant to Section 3(a) above, if at any time the Company
          grants, issues or sells any Common Stock Equivalents or rights to purchase stock, warrants, securities or other property pro rata to the record holders of any class of shares of Common Stock (the &#8220;<u>Purchase Rights</u>&#8221;), then the Holder will be
          entitled to acquire, upon the terms applicable to such Purchase Rights, the aggregate Purchase Rights which the Holder could have acquired if the Holder had held the number of shares of Common Stock acquirable upon complete exercise of this
          Warrant (without regard to any limitations on exercise hereof, including without limitation, the Beneficial Ownership Limitation) immediately before the date on which a record is taken for the grant, issuance or sale of such Purchase Rights, or,
          if no such record is taken, the date as of which the record holders of shares of Common Stock are to be determined for the grant, issue or sale of such Purchase Rights (provided, however, that, to the extent that the Holder&#8217;s right to participate
          in any such Purchase Right would result in the Holder exceeding the Beneficial Ownership Limitation, then the Holder shall not be entitled to participate in such Purchase Right to such extent (or beneficial ownership of such shares of Common
          Stock as a result of such Purchase Right to such extent) and such Purchase Right to such extent shall be held in abeyance for the Holder until such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial
          Ownership Limitation).</font></div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">c)&#160;&#160;&#160;&#160;&#160;&#160; <u>Pro Rata Distributions</u>.&#160; During such time as this Warrant is outstanding, if the Company shall declare or make any dividend or other distribution of its assets
        (or rights to acquire its assets) to holders of shares of Common Stock, by way of return of capital or otherwise (including, without limitation, any distribution of cash, stock or other securities, property or options by way of a dividend, spin
        off, reclassification, corporate rearrangement, scheme of arrangement or other similar transaction) (a &#8220;<u>Distribution</u>&#8221;), at any time after the issuance of this Warrant, then, in each such case, the Holder shall be entitled to participate in
        such Distribution to the same extent that the Holder would have participated therein if the Holder had held the number of shares of Common Stock acquirable upon complete exercise of this Warrant (without regard to any limitations on exercise
        hereof, including without limitation, the Beneficial Ownership Limitation) immediately before the date of which a record is taken for such Distribution, or, if no such record is taken, the date as of which the record holders of shares of Common
        Stock are to be determined for the participation in such Distribution (<u>provided</u>, <u>however</u>, that, to the extent that the Holder's right to participate in any such Distribution would result in the Holder exceeding the Beneficial
        Ownership Limitation, then the Holder shall not be entitled to participate in such Distribution to such extent (or in the beneficial ownership of any shares of Common Stock as a result of such Distribution to such extent) and the portion of such
        Distribution shall be held in abeyance for the benefit of the Holder until such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership Limitation).</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">10</font></div>
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      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">d)&#160;&#160;&#160;&#160; &#160; <u>Fundamental Transaction</u>. If, at any time while this Warrant is outstanding, (i) the Company, directly or indirectly, in one or more related transactions effects
        any merger or consolidation of the Company with or into another Person, (ii) the Company or any Subsidiary, directly or indirectly, effects any sale, lease, license, assignment, transfer, conveyance or other disposition of all or substantially all
        of its assets in one or a series of related transactions, (iii) any, direct or indirect, purchase offer, tender offer or exchange offer (whether by the Company or another Person) is completed pursuant to which holders of Common Stock are permitted
        to sell, tender or exchange their shares for other securities, cash or property and has been accepted by the holders of greater than 50% of the outstanding Common Stock or greater than 50% of the voting power of the common equity of the Company,
        (iv) the Company, directly or indirectly, in one or more related transactions effects any reclassification, reorganization or recapitalization of the Common Stock or any compulsory share exchange pursuant to which the Common Stock is effectively
        converted into or exchanged for other securities, cash or property, or (v) the Company<a name="OLE_LINK5"></a><a name="OLE_LINK6"></a>, directly or indirectly, in one or more related transactions consummates a stock or share purchase agreement or
        other business combination (including, without limitation, a reorganization, recapitalization, spin-off, merger or scheme of arrangement) with another Person or group of Persons whereby such other Person or group acquires greater than 50% of the
        outstanding shares of Common Stock or greater than 50% of the voting power of the common equity of the Company (each a &#8220;<u>Fundamental Transaction</u>&#8221;), then, upon any subsequent exercise of this Warrant, the Holder shall have the right to
        receive, for each Warrant Share that would have been issuable upon such exercise immediately prior to the occurrence of such Fundamental Transaction, at the option of the Holder (without regard to any limitation in Section 2(e) on the exercise of
        this Warrant), the number of shares of Common Stock of the successor or acquiring corporation or of the Company, if it is the surviving corporation, and any additional consideration (the &#8220;<u>Alternate Consideration</u>&#8221;) receivable as a result of
        such Fundamental Transaction by a holder of the number of shares of Common Stock for which this Warrant is exercisable immediately prior to such Fundamental Transaction (without regard to any limitation in Section 2(e) on the exercise of this
        Warrant).&#160; For purposes of any such exercise, the determination of the Exercise Price shall be appropriately adjusted to apply to such Alternate Consideration based on the amount of Alternate Consideration issuable in respect of one share of Common
        Stock in such Fundamental Transaction, and the Company shall apportion the Exercise Price among the Alternate Consideration in a reasonable manner reflecting the relative value of any different components of the Alternate Consideration.&#160; If holders
        of Common Stock are given any choice as to the securities, cash or property to be received in a Fundamental Transaction, then the Holder shall be given the same choice as to the Alternate Consideration it receives upon any exercise of this Warrant
        following such Fundamental Transaction.&#160; The Company shall cause any successor entity in a Fundamental Transaction in which the Company is not the survivor (the &#8220;<u>Successor Entity</u>&#8221;) to assume in writing all of the obligations of the Company
        under this Warrant in accordance with the provisions of this Section 3(d) pursuant to written agreements in form and substance reasonably satisfactory to the Holder and approved by the Holder (without unreasonable delay) prior to such Fundamental
        Transaction and shall, at the option of the Holder, deliver to the Holder in exchange for this Warrant a security of the Successor Entity evidenced by a written instrument substantially similar in form and substance to this Warrant which is
        exercisable for a corresponding number of shares of capital stock of such Successor Entity (or its parent entity) equivalent to the shares of Common Stock acquirable and receivable upon exercise of this Warrant (without regard to any limitations on
        the exercise of this Warrant) prior to such Fundamental Transaction, and with an exercise price which applies the exercise price hereunder to such shares of capital stock (but taking into account the relative value of the shares of Common Stock
        pursuant to such Fundamental Transaction and the value of such shares of capital stock, such number of shares of capital stock and such exercise price being for the purpose of protecting the economic value of this Warrant immediately prior to the
        consummation of such Fundamental Transaction), and which is reasonably satisfactory in form and substance to the Holder. Upon the occurrence of any such Fundamental Transaction, the Successor Entity shall be added to the term &#8220;Company&#8221; under this
        Warrant (so that from and after the occurrence or consummation of such Fundamental Transaction, each and every provision of this Warrant and the other Transaction Documents referring to the &#8220;Company&#8221; shall refer instead to each of the Company and
        the Successor Entity or Successor Entities, jointly and severally), and the Successor Entity or Successor Entities, jointly and severally with the Company, may exercise every right and power of the Company prior thereto and the Successor Entity or
        Successor Entities shall assume all of the obligations of the Company prior thereto under this Warrant and the other Transaction Documents with the same effect as if the Company and such Successor Entity or Successor Entities, jointly and
        severally, had been named as the Company herein. For the avoidance of doubt, the Holder shall be entitled to the benefits of the provisions of this Section 3(d) regardless of (i) whether the Company has sufficient authorized shares of Common Stock
        for the issuance of Warrant Shares and/or (ii) whether a Fundamental Transaction occurs prior to the Initial Exercise Date.</div>
      <div>&#160;</div>
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        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">11</font></div>
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      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">e)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Calculations</u>. All calculations under this Section 3 shall be made to the nearest cent or the nearest 1/100th of a share, as the case may be. For purposes of
        this Section 3, the number of shares of Common Stock deemed to be issued and outstanding as of a given date shall be the sum of the number of shares of Common Stock (excluding treasury shares, if any) issued and outstanding.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">f)&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Notice to Holder</u>.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 108pt;">i.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<u>Adjustment to Exercise Price</u>. Whenever the Exercise Price is adjusted pursuant to any provision of this Section 3, the Company shall promptly deliver to the
        Holder by email a notice setting forth the Exercise Price after such adjustment and any resulting adjustment to the number of Warrant Shares and setting forth a brief statement of the facts requiring such adjustment.</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">12</font></div>
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      <div style="text-align: justify; text-indent: 36pt; margin-left: 108pt;">ii.&#160;&#160;&#160;&#160;&#160;&#160; &#160; &#160; <u>Notice to Allow Exercise by Holder</u>. If (A) the Company shall declare a dividend (or any other distribution in whatever form) on the Common Stock, (B) the
        Company shall declare a special nonrecurring cash dividend on or a redemption of the Common Stock, (C) the Company shall authorize the granting to all holders of the Common Stock rights or warrants to subscribe for or purchase any shares of capital
        stock of any class or of any rights, (D) the approval of any stockholders of the Company shall be required in connection with any reclassification of the Common Stock, any consolidation or merger to which the Company (or any of its Subsidiaries) is
        a party, any sale or transfer of all or substantially all of its assets, or any compulsory share exchange whereby the Common Stock is converted into other securities, cash or property, or (E) the Company shall authorize the voluntary or involuntary
        dissolution, liquidation or winding up of the affairs of the Company, then, in each case, the Company shall cause to be delivered by email to the Holder at its last email address as it shall appear upon the Warrant Register of the Company, at least
        20 calendar days prior to the applicable record or effective date hereinafter specified, a notice stating (x) the date on which a record is to be taken for the purpose of such dividend, distribution, redemption, rights or warrants, or if a record
        is not to be taken, the date as of which the holders of the Common Stock of record to be entitled to such dividend, distributions, redemption, rights or warrants are to be determined or (y) the date on which such reclassification, consolidation,
        merger, sale, transfer or share exchange is expected to become effective or close, and the date as of which it is expected that holders of the Common Stock of record shall be entitled to exchange their shares of the Common Stock for securities,
        cash or other property deliverable upon such reclassification, consolidation, merger, sale, transfer or share exchange; provided that the failure to deliver such notice or any defect therein or in the delivery thereof shall not affect the validity
        of the corporate action required to be specified in such notice.&#160; To the extent that any notice provided in this Warrant constitutes, or contains, material, non-public information regarding the Company or any of the Subsidiaries, the Company shall
        simultaneously file such notice with the Commission pursuant to a Current Report on Form 8-K.&#160; The Holder shall remain entitled to exercise this Warrant during the period commencing on the date of such notice to the effective date of the event
        triggering such notice except as may otherwise be expressly set forth herein.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">g)&#160;&#160;&#160;&#160;&#160;&#160; <u>Voluntary Adjustment By Company</u>.&#160; Subject to the rules and regulations of the Trading Market, the Company may at any time during the term of this Warrant reduce
        the then current Exercise Price to any amount and for any period of time deemed appropriate by the board of directors of the Company.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt;"><u>Section 4</u>.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<u>Transfer of Warrant</u>.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">a)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Transferability</u>.&#160; This Warrant and all rights hereunder (including, without limitation, any registration rights) are transferable, in whole or in part, upon
        surrender of this Warrant at the principal office of the Company or its designated agent, together with a written assignment of this Warrant substantially in the form attached hereto duly executed by the Holder or its agent or attorney and funds
        sufficient to pay any transfer taxes payable upon the making of such transfer.&#160; Upon such surrender and, if required, such payment, the Company shall execute and deliver a new Warrant or Warrants in the name of the assignee or assignees, as
        applicable, and in the denomination or denominations specified in such instrument of assignment, and shall issue to the assignor a new Warrant evidencing the portion of this Warrant not so assigned, and this Warrant shall promptly be cancelled.&#160;
        Notwithstanding anything herein to the contrary, the Holder shall not be required to physically surrender this Warrant to the Company unless the Holder has assigned this Warrant in full, in which case, the Holder shall surrender this Warrant to the
        Company within three (3) Trading Days of the date on which the Holder delivers an assignment form to the Company assigning this Warrant in full.&#160; The Warrant, if properly assigned in accordance herewith, may be exercised by a new holder for the
        purchase of Warrant Shares without having a new Warrant issued.</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">13</font></div>
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      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">b)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>New Warrants</u>. This Warrant may be divided or combined with other Warrants upon presentation hereof at the aforesaid office of the Company, together with a
        written notice specifying the names and denominations in which new Warrants are to be issued, signed by the Holder or its agent or attorney.&#160; Subject to compliance with Section 4(a), as to any transfer which may be involved in such division or
        combination, the Company shall execute and deliver a new Warrant or Warrants in exchange for the Warrant or Warrants to be divided or combined in accordance with such notice. All Warrants issued on transfers or exchanges shall be dated the initial
        issuance date of this Warrant and shall be identical with this Warrant except as to the number of Warrant Shares issuable pursuant thereto.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">c)&#160;&#160;&#160;&#160;&#160;&#160; <u>Warrant Register</u>. The Company shall register this Warrant, upon records to be maintained by the Company for that purpose (the &#8220;<u>Warrant Register</u>&#8221;), in the
        name of the record Holder hereof from time to time.&#160; The Company may deem and treat the registered Holder of this Warrant as the absolute owner hereof for the purpose of any exercise hereof or any distribution to the Holder, and for all other
        purposes, absent actual notice to the contrary.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt;"><u>Section 5</u>.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<u>Miscellaneous</u>.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">a)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u></u><u>No Rights as Stockholder Until Exercise; No Settlement in Cash</u>.&#160; This Warrant does not entitle the Holder to any voting rights, dividends or other rights
        as a stockholder of the Company prior to the exercise hereof as set forth in Section 2(d)(i), except as expressly set forth in Section 3.&#160; Without limiting any rights of a Holder to receive Warrant Shares on a &#8220;cashless exercise&#8221; pursuant to
        Section 2(c) or to receive cash payments pursuant to Section 2(d)(i) and Section 2(d)(iv) herein, in no event shall the Company be required to net cash settle an exercise of this Warrant.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">b)&#160;&#160;&#160;&#160;&#160; <u>Loss, Theft, Destruction or Mutilation of Warrant</u>. The Company covenants that upon receipt by the Company of evidence reasonably satisfactory to it of the loss,
        theft, destruction or mutilation of this Warrant or any stock certificate relating to the Warrant Shares, and in case of loss, theft or destruction, of indemnity or security reasonably satisfactory to it (which, in the case of the Warrant, shall
        not include the posting of any bond), and upon surrender and cancellation of such Warrant or stock certificate, if mutilated, the Company will make and deliver a new Warrant or stock certificate of like tenor and dated as of such cancellation, in
        lieu of such Warrant or stock certificate.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">c)&#160;&#160;&#160; &#160; &#160; <u>Saturdays, Sundays, Holidays, etc</u>.&#160; If the last or appointed day for the taking of any action or the expiration of any right required or granted herein shall
        not be a Business Day, then such action may be taken or such right may be exercised on the next succeeding Business Day.</div>
      <div>&#160;</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="text-align: center;" class="BRPFPageNumberArea"><font style="font-size: 8pt; font-weight: normal; font-style: normal;">14</font></div>
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      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">d)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Authorized Shares</u>.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 72pt; margin-left: 72pt;">The Company covenants that, during the period the Warrant is outstanding, it will reserve from its authorized and unissued Common Stock a sufficient number of shares to provide
        for the issuance of the Warrant Shares upon the exercise of any purchase rights under this Warrant.&#160; The Company further covenants that its issuance of this Warrant shall constitute full authority to its officers who are charged with the duty of
        issuing the necessary Warrant Shares upon the exercise of the purchase rights under this Warrant.&#160; The Company will take all such reasonable action as may be necessary to assure that such Warrant Shares may be issued as provided herein without
        violation of any applicable law or regulation, or of any requirements of the Trading Market upon which the Common Stock may be listed.&#160; The Company covenants that all Warrant Shares which may be issued upon the exercise of the purchase rights
        represented by this Warrant will, upon exercise of the purchase rights represented by this Warrant and payment for such Warrant Shares in accordance herewith, be duly authorized, validly issued, fully paid and nonassessable and free from all taxes,
        liens and charges created by the Company in respect of the issue thereof (other than taxes in respect of any transfer occurring contemporaneously with such issue).</div>
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      <div style="text-align: justify; margin-left: 72pt; text-indent: 27pt;">Except and to the extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation, amending its certificate of incorporation or
        through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or sale of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant, but will at all
        times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary or appropriate to protect the rights of Holder as set forth in this Warrant against impairment.&#160; Without limiting the
        generality of the foregoing, the Company will (i) not increase the par value of any Warrant Shares above the amount payable therefor upon such exercise immediately prior to such increase in par value, (ii) take all such action as may be necessary
        or appropriate in order that the Company may validly and legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant and (iii) use commercially reasonable efforts to obtain all such authorizations, exemptions or
        consents from any public regulatory body having jurisdiction thereof, as may be, necessary to enable the Company to perform its obligations under this Warrant.</div>
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      <div style="text-align: justify; margin-left: 72pt; text-indent: 27pt;">Before taking any action which would result in an adjustment in the number of Warrant Shares for which this Warrant is exercisable or in the Exercise Price, the Company shall
        obtain all such authorizations or exemptions thereof, or consents thereto, as may be necessary from any public regulatory body or bodies having jurisdiction thereof.</div>
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      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
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      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">e)&#160;&#160;&#160;&#160;&#160; <u>Governing Law</u>. All questions <font style="color: rgb(0, 0, 0);">concerning the construction, validity, enforcement and interpretation of this Warrant shall be
          governed by and construed and enforced in accordance with the internal laws of the State of Delaware, without regard to the principles of conflicts of law thereof. Each party agrees that all legal proceedings concerning the interpretations,
          enforcement and defense of the transactions contemplated by this Warrant (whether brought against a party hereto or their respective affiliates, directors, officers, shareholders, partners, members, employees or agents) shall be commenced
          exclusively </font>in the Court of Chancery of the State of Delaware, provided that if subject matter jurisdiction over the matter that is the subject of the legal proceeding is vested exclusively in the U.S. federal courts, such legal
        proceeding shall be heard in the U.S. District Court for the District of Delaware <font style="color: rgb(0, 0, 0);">for the adjudication of any dispute hereunder or in connection herewith or with any transaction contemplated hereby or discussed
          herein, and hereby irrevocably waives, and agrees not to assert in any suit, action or proceeding, any claim that it is not personally subject to the jurisdiction of any such court, that such suit, action or proceeding is improper or is an
          inconvenient venue for such proceeding. Each party hereby irrevocably waives personal service of process and consents to process being served in any such suit, action or proceeding by mailing a copy thereof via registered or certified mail or
          overnight delivery (with evidence of delivery) to such party at the address in effect for notices to it under this Warrant and agrees that such service shall constitute good and sufficient service of process and notice thereof. Nothing contained
          herein shall be deemed to limit in any way any right to serve process in any other manner permitted by law. If either party shall commence an action, suit or proceeding to enforce any provisions of this Warrant, the prevailing party in such
          action, suit or proceeding shall be reimbursed by the other party for their reasonable attorneys&#8217; fees and other costs and expenses incurred with the investigation, preparation and prosecution of such action or proceeding</font>.</div>
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      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">f)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Restrictions</u>.&#160; The Holder acknowledges that the Warrant Shares acquired upon the exercise of this Warrant, if not registered, and the Holder does not utilize
        cashless exercise, will have restrictions upon resale imposed by state and federal securities laws.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">g)&#160;&#160;&#160;&#160;&#160;&#160; <u>Nonwaiver and Expenses</u>.&#160; No course of dealing or any delay or failure to exercise any right hereunder on the part of Holder shall operate as a waiver of such
        right or otherwise prejudice the Holder&#8217;s rights, powers or remedies.&#160; Without limiting any other provision of this Warrant, if the Company willfully and knowingly fails to comply with any provision of this Warrant, which results in any material
        damages to the Holder, the Company shall pay to the Holder such amounts as shall be sufficient to cover any costs and expenses including, but not limited to, reasonable attorneys&#8217; fees, including those of appellate proceedings, incurred by the
        Holder in collecting any amounts due pursuant hereto or in otherwise enforcing any of its rights, powers or remedies hereunder.</div>
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      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">h)&#160;&#160;&#160;&#160;&#160;&#160; <u>Notices</u><a name="z_DV_C47"></a>.&#160; Any and all notices or other communications or deliveries to be provided by the Holders hereunder including, without limitation,
        any Notice of Exercise, shall be in writing and delivered personally, by e-mail, or sent by a nationally recognized overnight courier service, addressed to the Company, at 8 Davis Drive, Suite 220, Durham<font style="font-weight: bold;">, </font>NC

        27709 Attention:<font style="font-weight: bold;">&#160;</font>Rob Gagnon, email address: rgagnon@opusgtx.com, or such other email address or address as the Company may specify for such purposes by notice to the Holders. Any and all notices or other
        communications or deliveries to be provided by the Company hereunder shall be in writing and delivered personally, by e-mail, or sent by a nationally recognized overnight courier service addressed to each Holder at the e-mail address or address of
        such Holder appearing on the books of the Company. Any notice or other communication or deliveries hereunder shall be deemed given and effective on the earliest of (i) the time of transmission, if such notice or communication is delivered via
        e-mail at the e-mail address set forth in this Section prior to 5:30 p.m. (New York City time) on any date, (ii) the next Trading Day after the time of transmission, if such notice or communication is delivered via e-mail at the e-mail address set
        forth in this Section on a day that is not a Trading Day or later than 5:30 p.m. (New York City time) on any Trading Day, (iii) the second Trading Day following the date of mailing, if sent by U.S. nationally recognized overnight courier service,
        or (iv) upon actual receipt by the party to whom such notice is required to be given.&#160; To the extent that any notice provided hereunder constitutes, or contains, material, non-public information regarding the Company or any Subsidiaries, the
        Company shall simultaneously file such notice with the Commission pursuant to a Current Report on Form 8-K.</div>
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      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
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      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">i)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Limitation of Liability</u>.&#160; No provision hereof, in the absence of any affirmative action by the Holder to exercise this Warrant to purchase Warrant Shares, and
        no enumeration herein of the rights or privileges of the Holder, shall give rise to any liability of the Holder for the purchase price of any Common Stock or as a stockholder of the Company, whether such liability is asserted by the Company or by
        creditors of the Company.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">j)&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u>Remedies</u>.&#160; The Holder, in addition to being entitled to exercise all rights granted by law, including recovery of damages, will be entitled to specific
        performance of its rights under this Warrant.&#160; The Company agrees that monetary damages would not be adequate compensation for any loss incurred by reason of a breach by it of the provisions of this Warrant and hereby agrees to waive and not to
        assert the defense in any action for specific performance that a remedy at law would be adequate.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">k)&#160;&#160;&#160;&#160;&#160;&#160; <u>Successors and Assigns</u>.&#160; Subject to applicable securities laws, this Warrant and the rights and obligations evidenced hereby shall inure to the benefit of and be
        binding upon the successors and permitted assigns of the Company and the successors and permitted assigns of Holder.&#160; The provisions of this Warrant are intended to be for the benefit of any Holder from time to time of this Warrant and shall be
        enforceable by the Holder or holder of Warrant Shares.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">l)&#160;&#160;&#160;&#160;&#160; <u>Amendment</u>.&#160; This Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company, on the one hand, <font style="color: rgb(0, 0, 0);">and the Holder or the beneficial owner of this Warrant, on the other hand</font>.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">m)&#160;&#160;&#160;&#160;&#160; <u>Severability</u>.&#160; Wherever possible, each provision of this Warrant shall be interpreted in such manner as to be effective and valid under applicable law, but if any
        provision of this Warrant shall be prohibited by or invalid under applicable law, such provision shall be ineffective to the extent of such prohibition or invalidity, without invalidating the remainder of such provisions or the remaining provisions
        of this Warrant.</div>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">n)&#160;&#160;&#160;&#160;&#160;&#160; <u>Headings</u>.&#160; The headings used in this Warrant are for the convenience of reference only and shall not, for any purpose, be deemed a part of this Warrant.</div>
      <div>&#160;</div>
      <div style="text-align: center;">********************</div>
      <div><br>
      </div>
      <div style="text-align: center; font-style: italic;">(Signature Page Follows)</div>
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      <div style="text-align: justify; text-indent: 72pt;">IN WITNESS WHEREOF, the Company has caused this Warrant to be executed by its officer thereunto duly authorized as of the date first above indicated.</div>
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              <div style="font-weight: bold;">OPUS GENETICS, INC.</div>
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              <div><br>
              </div>
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              <div>Name: George Magrath, MD</div>
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      <div style="text-align: center; font-weight: bold;">NOTICE OF EXERCISE</div>
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      <div>TO: OPUS GENETICS, INC.</div>
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      <div style="text-align: justify; text-indent: 72pt;">(1) The undersigned hereby elects to purchase ________ Warrant Shares of the Company pursuant to the terms of the attached Warrant (only if exercised in full), and tenders herewith payment of the
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      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 72pt;">(3) Please issue said Warrant Shares in the name of the undersigned or in such other name as is specified below:</div>
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      <div style="text-align: justify;">The Warrant Shares shall be delivered to the following DWAC Account Number:</div>
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              <td style="width: 35%; border-bottom: 2px solid rgb(0, 0, 0);">
                <div>&#160;</div>
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                <div>&#160;</div>
              </td>
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                <div>&#160;</div>
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                <div>&#160;</div>
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      <div style="text-align: justify;">[SIGNATURE OF HOLDER]</div>
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              <div style="text-align: justify; color: rgb(0, 0, 0);">(Please Print)</div>
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            <td style="width: 43%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);" rowspan="1">&#160;</td>
            <td style="width: 10%; vertical-align: top; padding-bottom: 2px;" rowspan="1">&#160;</td>
          </tr>
          <tr>
            <td style="vertical-align: top;" rowspan="1" colspan="2">&#160;</td>
            <td style="width: 43%; vertical-align: top;" rowspan="1">&#160;</td>
            <td style="width: 10%; vertical-align: top;" rowspan="1">&#160;</td>
          </tr>
          <tr>
            <td style="vertical-align: top;" colspan="2">
              <div style="text-align: justify;">Dated: _______________ __, ______</div>
            </td>
            <td style="vertical-align: top;" colspan="2">&#160;</td>
          </tr>
          <tr>
            <td style="vertical-align: top;" colspan="2" rowspan="1">&#160;</td>
            <td style="vertical-align: top;" colspan="2" rowspan="1">&#160;</td>
          </tr>
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            <td nowrap="nowrap" style="width: 12%; vertical-align: top; padding-bottom: 2px;">
              <div style="text-align: justify;">Holder&#8217;s Signature: <br>
              </div>
            </td>
            <td style="width: 35%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">&#160;</td>
            <td style="vertical-align: top; padding-bottom: 2px;" colspan="2">&#160;</td>
          </tr>
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            <td style="width: 12%; vertical-align: top;" rowspan="1">&#160;</td>
            <td style="width: 35%; vertical-align: top;" rowspan="1">&#160;</td>
            <td style="vertical-align: top;" colspan="2" rowspan="1">&#160;</td>
          </tr>
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            <td style="width: 12%; vertical-align: top; padding-bottom: 2px;">
              <div style="text-align: justify;">Holder&#8217;s Address:<br>
              </div>
            </td>
            <td style="width: 35%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">&#160;</td>
            <td style="vertical-align: top; padding-bottom: 2px;" colspan="2">&#160;</td>
          </tr>

      </table>
      <div><br>
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      <div>&#160;</div>
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<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>ny20058362x2_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
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      <div style="text-align: right; font-weight: bold;">Exhibit 5.1</div>
      <div style="text-align: right; font-weight: bold;"> <br>
      </div>
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              <div><a name="HeaderOne"></a><img width="115" height="30" src="ny20058362x2_ex5-1logo01.jpg"></div>
            </td>
            <td style="width: 37%; vertical-align: top;">
              <div><a name="swiOFCompanyName"></a><a name="swiOFCompanyName1"></a></div>
              <div>SIDLEY AUSTIN LLP</div>
              <div>2850 QUARRY LAKE DRIVE, SUITE 280</div>
              <div>BALTIMORE, MD 21209</div>
              <div>+1 410 559 2880</div>
              <div>+1 202 736 8711 FAX</div>
            </td>
            <td style="width: 32.66%; vertical-align: top;">&#160;</td>
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    <div>
      <div style="text-align: center;">November 6, 2025</div>
      <div><br>
      </div>
      <div style="margin-right: 7.9pt;">Opus Genetics, Inc.</div>
      <div style="margin-right: 7.9pt;">8 Davis Drive, Suite 220</div>
      <div style="margin-right: 7.9pt;">Durham, NC 27709</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt; margin-left: 36pt;">Re: <u>Registration Statement on Form S-3</u></div>
      <div><br>
      </div>
      <div style="text-align: justify;">Ladies and Gentlemen:</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;">We refer to the Registration Statement on Form S-3, File No. 333-276462, filed by Opus Genetics, Inc. (f/k/a Ocuphire Pharma, Inc.), a Delaware corporation (the &#8220;<u>Company</u>&#8221;), with the
        Securities and Exchange Commission (the &#8220;<u>SEC</u>&#8221;) under the Securities Act of 1933, as amended (the &#8220;<u>Securities Act</u>&#8221;), which was initially filed with the SEC on January 10, 2024 and declared effective by the SEC on January 23, 2024 (the
        &#8220;<u>Registration Statement</u>&#8221;). Pursuant to the Registration Statement, the Company is issuing up to (a) 3,827,751 shares (the &#8220;<u>Common Shares</u>&#8221;) of its common stock, $0.0001 par value per share (the &#8220;<u>Common Stock</u>&#8221;) and (b) pre-funded
        warrants to purchase an aggregate of 7,177,033 shares of Common Stock (the &#8220;<u>Pre-Funded Warrant Shares</u>&#8221;) with an exercise price of $0.0001 per share (the &#8220;<u>Pre-Funded Warrants</u>&#8221; and together with the Common Shares, and the Pre-Funded
        Warrants Shares, the &#8220;<u>Securities</u>&#8221;). The Securities are to be sold by the Company pursuant to a purchase agreement dated November 5, 2025 (the &#8220;<u>Purchase Agreement</u>&#8221;) between the Company and the purchasers named therein (the &#8220;<u>Purchasers</u>&#8221;).</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;">This opinion letter is being delivered in accordance with the requirements of Item 601(b)(5) of Regulation S-K under the Securities Act.</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;">We have examined the Registration Statement, the Purchase Agreement, the form of Pre-Funded Warrants, the Company&#8217;s certificate of incorporation, as currently in effect, the Company's bylaws, as
        currently in effect, and the written consents and resolutions adopted by the board of directors of the Company relating to the Registration Statement and the issuance of the Securities by the Company. We have also examined originals, or copies of
        originals certified to our satisfaction, of such agreements, documents, certificates and statements of the Company and other corporate documents and instruments, and have examined such questions of law, as we have considered relevant and necessary
        as a basis for this opinion letter. We have assumed the authenticity and completeness of all documents submitted to us as originals, the genuineness of all signatures, the legal capacity of all persons and the conformity with the original documents
        of any copies thereof submitted to us for examination. As to facts relevant to the opinions expressed herein, we have relied without independent investigation or verification upon, and assumed the accuracy and completeness of, certificates, letters
        and oral and written statements and representations of public officials and officers and other representatives of the Company.</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 18pt;">Based on and subject to the foregoing and the other limitations, qualifications and assumptions set forth herein, we are of the opinion that:</div>
      <div><br>
      </div>
      <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zed9fc75ff439411db2eccc556f70a1f2">

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            <td style="width: 18pt;"><br>
            </td>
            <td style="width: 18pt; vertical-align: top;">1.</td>
            <td style="width: auto; vertical-align: top; text-align: justify;">
              <div>The issuance and sale of the Common Shares covered by the Registration Statement pursuant to the Purchase Agreement have been duly authorized by the Company, and such Common Shares will be validly issued, fully paid and non-assessable
                when the Company&#8217;s books shall reflect the issuance of such Common Shares to the purchasers thereof against payment of the agreed consideration therefor in an amount not less than the par value thereof in accordance with the Purchase
                Agreement.</div>
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      <div><br>
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          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div> <img width="115" border="0" height="30" src="ny20058362x2_ex5-1logo01.jpg"></div>
      <div> Opus Genetics, Inc.<br>
      </div>
      <div>November 6, 2025<br>
      </div>
      <div>Page 2<br>
      </div>
      <div> <br>
      </div>
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            <td style="width: 18pt;"><br>
            </td>
            <td style="width: 18pt; vertical-align: top;">2.</td>
            <td style="width: auto; vertical-align: top; text-align: justify;">
              <div>The issuance and sale of the Pre-Funded Warrants covered by the Registration Statement pursuant to the Purchase Agreement have been duly authorized by the Company, and such Pre-Funded Warrants will be valid and binding obligations of the
                Company when such Pre-Funded Warrants shall have been duly executed, countersigned and registered and duly delivered to the purchasers thereof against payment of the agreed consideration therefor, in accordance with the Purchase Agreement.</div>
            </td>
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      </table>
      <div>&#160;</div>
      <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z4ce1679ba6c7496fb127f32a0b39410b">

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            <td style="width: 18pt;"><br>
            </td>
            <td style="width: 18pt; vertical-align: top;">3.</td>
            <td style="width: auto; vertical-align: top; text-align: justify;">
              <div>The issuance of the Pre-Funded Warrant Shares issuable upon exercise of the Pre-Funded Warrants covered by the Registration Statement pursuant to the terms of the Pre-Funded Warrants has been duly authorized by the Company, and such
                Pre-Funded Warrant Shares will be validly issued, fully paid and non-assessable when the Company&#8217;s books shall reflect the issuance of such Pre-Funded Warrant Shares to the holders thereof against payment of the exercise price therefor, in
                accordance with the terms of the Pre-Funded Warrants.</div>
            </td>
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      </table>
      <div>&#160;</div>
      <div style="text-align: justify; text-indent: 18pt;">For the purposes of paragraph 3 of this opinion letter, we have assumed that, at the time of the issuance and delivery of the Pre-Funded Warrant Shares issuable upon exercise of the Pre-Funded
        Warrants: (i) the authorization thereof by the Company will not have been modified or rescinded, and there will not have occurred any change in law affecting the validity thereof; (ii) the certificate of incorporation and bylaws of the Company,
        each as currently in effect, will not have been modified or amended and will be in full force and effect; and (iii) there will be a sufficient number of shares of Common Stock authorized and then available for issuance under the Company&#8217;s
        certificate of incorporation as then in effect.</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 18pt;">We express no opinion as to any provision of any instrument, agreement or other document (i) regarding severability of the provisions thereof; (ii) providing that the assertion or employment of any
        right or remedy shall not prevent the concurrent assertion or employment of any other right or remedy, or that every right and remedy shall be cumulative and in addition to every other right and remedy, or that any delay or omission to exercise any
        right or remedy shall not impair any right or remedy or constitute a waiver thereof; (iii) imposing liquidated damages or penalties; (iv) regarding waiver of usury, stay, extension or similar laws; (v) regarding any obligation or agreement to use
        best efforts, reasonable best efforts or commercially reasonable efforts or any similar obligation or agreement; (vi) regarding choice of law; (vii) regarding specific performance or the grant of any power of attorney; or (viii) requiring any party
        to take further action or to enter into further agreements or instruments or to provide further assurances,</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 18pt;">Our opinions are subject to bankruptcy, insolvency, reorganization, moratorium, fraudulent conveyance, fraudulent transfer and other similar laws relating to or affecting creditors&#8217; rights
        generally and to general equitable principles (regardless of whether considered in a proceeding in equity or at law), including concepts of commercial reasonableness, good faith and fair dealing and the possible unavailability of specific
        performance or injunctive relief.</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 18pt;">This opinion letter is limited to the General Corporation Law of the State of Delaware and the laws of the State of New York (excluding the securities laws of the State of New York).&#160; We express no
        opinion as to the laws, rules or regulations of any other jurisdiction, including, without limitation, the federal laws of the United States of America or any state securities or blue sky laws.</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 18pt;">We hereby consent to the filing of this opinion letter as an Exhibit to the Registration Statement and to all references to our Firm included in or made a part of the Registration Statement.&#160; In
        giving such consent, we do not thereby admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act.</div>
      <div><br>
      </div>
      <div>
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                <div>&#160;</div>
              </td>
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                <div style="text-align: justify;">Very truly yours,</div>
              </td>
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                <div>&#160;</div>
              </td>
              <td style="width: 40%;">
                <div>&#160;</div>
              </td>
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                <div>&#160;</div>
              </td>
              <td style="width: 40%;">
                <div style="text-align: justify;">/s/ Sidley Austin LLP</div>
              </td>
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      <div style="text-align: justify; text-indent: 36pt; margin-left: 252pt;"><br>
      </div>
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<DOCUMENT>
<TYPE>EX-10.1
<SEQUENCE>4
<FILENAME>ny20058362x2_ex10-1.htm
<DESCRIPTION>EXHIBIT 10.1
<TEXT>
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    <div style="text-align: right;"><font style="font-weight: bold;">Exhibit 10.1</font><br>
    </div>
    <div><br>
    </div>
    <div>
      <div style="text-align: center;"><font style="color: #262626;">SECURITIES </font><font style="color: #131313;">PURCHASE AGREEMENT</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #262626;">This </font><font style="color: #131313;">Securities </font><font style="color: #262626;">Purchase </font><font style="color: #131313;">Agreement </font><font style="color: #262626;">(this </font><font style="color: #464646;">&#8220;</font><font style="color: #131313;"><u>Agreement</u></font><font style="color: #363636;">&#8221;) </font><font style="color: #131313;">is </font><font style="color: #262626;">dated
          as of November 5</font><font style="color: #5B5B5B;">, </font><font style="color: #262626;">2025, between Opus Genetics, Inc., a Delaware corporation (the </font><font style="color: #464646;">&#8220;</font><font style="color: #131313;"><u>Company</u></font><font style="color: #464646;">&#8221;</font><font style="color: #262626;">), and each purchaser identified on the signature pages hereto (each, </font><font style="color: #131313;">including its </font><font style="color: #262626;">successors and assigns,
        </font><font style="color: #363636;">a </font><font style="color: #5B5B5B;">&#8220;</font><font style="color: #131313;"><u>Purchaser</u></font><font style="color: #363636;">&#8221; </font><font style="color: #262626;">and collectively the </font><font style="color: #363636;">&#8220;<u>Purchasers</u>&#8221;).</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #262626;">WHEREAS</font><font style="color: #5B5B5B;">, </font><font style="color: #262626;">subject to </font><font style="color: #363636;">the </font><font style="color: #262626;">terms and conditions set forth </font><font style="color: #131313;">in </font><font style="color: #262626;">this Agreement and pursuant to an effective </font><font style="color: #363636;">registration </font><font style="color: #262626;">statement under </font><font style="color: #131313;">the </font><font style="color: #262626;">Securities Act (as </font><font style="color: #131313;">defined below)</font><font style="color: #464646;">, </font><font style="color: #262626;">the Company desires to issue and sell to each </font><font style="color: #131313;">Purchaser</font><font style="color: #696969;">, </font><font style="color: #262626;">and each Purchaser, severally and </font><font style="color: #131313;">not </font><font style="color: #262626;">jointly, desires </font><font style="color: #363636;">to </font><font style="color: #131313;">purchase from </font><font style="color: #262626;">the Company, securities of the Company as more
          fully described </font><font style="color: #131313;">in </font><font style="color: #363636;">this </font><font style="color: #131313;">Agreement.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #131313;">NOW</font><font style="color: #5B5B5B;">, </font><font style="color: #131313;">THEREFORE</font><font style="color: #464646;">, </font><font style="color: #131313;">IN






        </font><font style="color: #262626;">CONSIDERATION of </font><font style="color: #131313;">the </font><font style="color: #262626;">mutual covenants contained </font><font style="color: #131313;">in </font><font style="color: #262626;">this
          Agreement, and for other good and valuable consideration the receipt and adequacy of which </font><font style="color: #363636;">are </font><font style="color: #262626;">hereby acknowledged, the </font><font style="color: #131313;">Company </font><font style="color: #262626;">and </font><font style="color: #363636;">each </font><font style="color: #131313;">Purchaser </font><font style="color: #262626;">agree as follows</font><font style="color: #5B5B5B;">:</font></div>
      <div><br>
      </div>
      <div style="text-align: center; color: #262626;">ARTICLE I.</div>
      <div style="text-align: center; color: #262626;">DEFINITIONS</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #262626;">1.1</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #131313;"><u>Definitions</u>. In </font><font style="color: #262626;">addition </font><font style="color: #131313;">to the
          terms defined elsewhere in </font><font style="color: #262626;">this </font><font style="color: #131313;">Agreement</font><font style="color: #5B5B5B;">, </font><font style="color: #131313;">for </font><font style="color: #262626;">al</font><font style="color: #131313;">l </font><font style="color: #262626;">purposes </font><font style="color: #131313;">of </font><font style="color: #262626;">this Agreeme</font><font style="color: #464646;">n</font><font style="color: #262626;">t</font><font style="color: #5B5B5B;">, </font><font style="color: #131313;">the following </font><font style="color: #262626;">terms have the meanings set </font><font style="color: #131313;">forth in this </font><font style="color: #262626;">Section 1.1:</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: rgb(105, 105, 105);">&#8220;</font><font style="color: rgb(19, 19, 19);"><u>Affi</u></font><font style="color: rgb(54, 54, 54);"><u>liate</u>&#8221; </font><font style="color: rgb(38, 38, 38);">means any Person that</font><font style="color: rgb(91, 91, 91);">, </font><font style="color: rgb(19, 19, 19);">directly </font><font style="color: rgb(38, 38, 38);">or </font><font style="color: rgb(19, 19, 19);">indirectly </font><font style="color: rgb(70, 70, 70);">through </font><font style="color: rgb(38, 38, 38);">one or more </font><font style="color: rgb(19, 19, 19);">intermediaries</font><font style="color: rgb(70, 70, 70);">, </font><font style="color: rgb(38, 38, 38);">controls </font><font style="color: rgb(19, 19, 19);">or is </font><font style="color: rgb(38, 38, 38);">controlled </font><font style="color: rgb(19, 19, 19);">by </font><font style="color: rgb(38, 38, 38);">or </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">under common </font><font style="color: rgb(19, 19, 19);">control </font><font style="color: rgb(38, 38, 38);">with a </font><font style="color: rgb(19, 19, 19);">Person






        </font><font style="color: rgb(38, 38, 38);">as such terms are used in and construed under Rule 405 under </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Securities </font><font style="color: rgb(19, 19, 19);">Act.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #5B5B5B;">&#8220;</font><font style="color: #131313;"><u>Board </u></font><font style="color: #262626;"><u>of </u></font><font style="color: #131313;"><u>Directors</u>&#8221; </font><font style="color: #262626;">means the board </font><font style="color: #363636;">of directors </font><font style="color: #464646;">of </font><font style="color: #262626;">the </font><font style="color: #363636;">Company.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #262626;">&#8220;<u>Business Day</u>&#8221; </font><font style="color: #131313;">means </font><font style="color: #262626;">any day </font><font style="color: #131313;">other </font><font style="color: #262626;">than Saturday</font><font style="color: #5B5B5B;">, </font><font style="color: #262626;">Sunday or </font><font style="color: #131313;">other </font><font style="color: #262626;">day on </font><font style="color: #131313;">which </font><font style="color: #262626;">commercial banks </font><font style="color: #131313;">in </font><font style="color: #262626;">New York, New York are authorized or required by </font><font style="color: #363636;">law </font><font style="color: #131313;">to </font><font style="color: #262626;">remain closed.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #262626;">&#8220;<u>Closing</u></font><font style="color: #5B5B5B;">&#8221; </font><font style="color: #262626;">means the closing of </font><font style="color: #131313;">the </font><font style="color: #262626;">purchase and sale of </font><font style="color: #131313;">the </font><font style="color: #262626;">Shares pursuant to Section 2.1.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #464646;">&#8220;<u>Closing </u></font><font style="color: #262626;"><u>Date</u>&#8221; means </font><font style="color: #363636;">the </font><font style="color: #464646;">Trading </font><font style="color: #363636;">Day on which all of </font><font style="color: #262626;">the </font><font style="color: #131313;">Transaction Documents have been </font><font style="color: #262626;">executed and delivered by </font><font style="color: #131313;">the </font><font style="color: #262626;">applicable </font><font style="color: #131313;">parties thereto</font><font style="color: #5B5B5B;">, </font><font style="color: #262626;">and all conditions prec</font><font style="color: #464646;">e</font><font style="color: #262626;">den</font><font style="color: #5B5B5B;">t </font><font style="color: #363636;">to </font><font style="color: #464646;">(i) </font><font style="color: #363636;">the Purchasers' </font><font style="color: #262626;">obligations </font><font style="color: #363636;">to pay the Subscription </font><font style="color: #464646;">Amount and </font><font style="color: #363636;">(ii) </font><font style="color: #464646;">the Company's </font><font style="color: #363636;">obligations </font><font style="color: #262626;">to deliver the Shares, </font><font style="color: #131313;">in </font><font style="color: #262626;">each case, have been </font><font style="color: #363636;">satisfied </font><font style="color: #262626;">or waived, but in </font><font style="color: #363636;">no </font><font style="color: #262626;">event </font><font style="color: #131313;">later </font><font style="color: #262626;">than the second (2</font><sup style="color: #262626; vertical-align: text-top; line-height: 1; font-size: smaller;">n</sup><sup style="color: #464646; vertical-align: text-top; line-height: 1; font-size: smaller;">d</sup><font style="color: #262626;">) Trading </font><font style="color: #131313;">Day </font><font style="color: #262626;">fol</font><font style="color: #131313;">lowing </font><font style="color: #262626;">the date hereof.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #424242;">&#8220;<u>Commission</u>&#8221; </font><font style="color: #232323;">means the United States Securities </font><font style="color: #424242;">and </font><font style="color: #232323;">Exchange </font><font style="color: #343434;">Commission</font><font style="color: #606060;">.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #232323;">&#8220;<u>Common Stock</u>&#8221; means the common stock of the Company, </font><font style="color: #343434;">par </font><font style="color: #232323;">value $0.0001 per share,
          and any other class of securities </font><font style="color: #0C0C0C;">into </font><font style="color: #232323;">which such securities may hereafter be reclassified or changed</font><font style="color: #606060;">.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #232323;">&#8220;<u>Common Stock Equivalents</u>&#8221; means any securities of </font><font style="color: #343434;">the </font><font style="color: #0C0C0C;">Company or </font><font style="color: #232323;">the Subsidiaries which would entitle the holder </font><font style="color: #343434;">thereof </font><font style="color: #232323;">to acquire at any time Common Stock, </font><font style="color: #0C0C0C;">including, </font><font style="color: #232323;">without </font><font style="color: #0C0C0C;">limi</font><font style="color: #424242;">t</font><font style="color: #232323;">ation, any debt, preferred stock, </font><font style="color: #343434;">right, </font><font style="color: #232323;">option, warrant or other </font><font style="color: #0C0C0C;">instrument </font><font style="color: #232323;">that is at any time convertible </font><font style="color: #343434;">into </font><font style="color: #232323;">or exercisable or exchangeable for, or otherwise entitles the holder thereof to </font><font style="color: #0C0C0C;">receive, </font><font style="color: #232323;">Common Stock.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #343434;">&#8220;<u>Company </u></font><font style="color: #232323;"><u>Counsel</u>&#8221; </font><font style="color: #343434;">means </font><font style="color: #232323;">Sidley Austin </font><font style="color: #0C0C0C;">LLP</font><font style="color: #424242;">.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #424242;">&#8220;<u>Disclosure </u></font><font style="color: #232323;"><u>Time</u>&#8221; means, (i) </font><font style="color: #0C0C0C;">if </font><font style="color: #343434;">this </font><font style="color: #232323;">Agreement </font><font style="color: #343434;">is </font><font style="color: #232323;">signed on a day that </font><font style="color: #0C0C0C;">is </font><font style="color: #232323;">not a</font>&#160;<font style="color: #0C0C0C;">Trading </font><font style="color: #232323;">Day or after 9</font><font style="color: #606060;">:</font><font style="color: #232323;">00 a</font><font style="color: #606060;">.</font><font style="color: #232323;">m</font><font style="color: #606060;">.</font><font style="color: #232323;">(New York City time) and before midnight (New York City</font>&#160;<font style="color: #232323;">time) on any </font><font style="color: #343434;">Trading </font><font style="color: #232323;">Day, 9</font><font style="color: #606060;">:</font><font style="color: #343434;">01 </font><font style="color: #232323;">a.m. (New York City time) on the </font><font style="color: #343434;">Trading </font><font style="color: #232323;">Day </font><font style="color: #0C0C0C;">immediately </font><font style="color: #232323;">following the date hereof, and (ii) </font><font style="color: #0C0C0C;">if </font><font style="color: #232323;">this </font><font style="color: #0C0C0C;">Agreement </font><font style="color: #232323;">is signed between midnight (New York City time) and 9:00 a.m. (New York City </font><font style="color: #343434;">time) </font><font style="color: #232323;">on any Trading
          Day, 9:01 a.m. (New </font><font style="color: #0C0C0C;">York </font><font style="color: #232323;">City time) on the date hereof.</font></div>
      <div><br>
      </div>
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      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #606060;">&#8220;</font><font style="color: #232323;"><u>Environmental Laws</u>&#8221; </font><font style="color: #424242;">shall </font><font style="color: #232323;">have </font><font style="color: #343434;">the meaning </font><font style="color: #232323;">assigned to such term in Section</font>&#160;<font style="color: #232323;">3.1(m).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #424242;">&#8220;<u>Exchange </u></font><font style="color: #232323;"><u>Act</u>&#8221; means the </font><font style="color: #424242;">Securities </font><font style="color: #606060;">E</font><font style="color: #232323;">xch</font><font style="color: #424242;">a</font><font style="color: #232323;">n</font><font style="color: #424242;">ge </font><font style="color: #343434;">Act </font><font style="color: #424242;">of </font><font style="color: #343434;">1934, as </font><font style="color: #424242;">amended, and </font><font style="color: #343434;">the</font></div>
      <div style="text-indent: 36pt;"><font style="color: #232323;">rules and regulations </font><font style="color: #343434;">promulgated </font><font style="color: #232323;">thereunder.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #424242;">&#8220;<u>Exempt </u></font><font style="color: #0C0C0C;"><u>Issuance</u>&#8221; </font><font style="color: #232323;">means the issuance of (a) shares of Common Stock, options,
          restricted stock awards, </font><font style="color: #424242;">restricted </font><font style="color: #232323;">stock units or other equity awards </font><font style="color: #343434;">to </font><font style="color: #232323;">employees, officers,
          directors, consultants or advisors of </font><font style="color: #343434;">the </font><font style="color: #232323;">Company </font><font style="color: #343434;">pursuant </font><font style="color: #232323;">to any stock or option plan </font><font style="color: #0C0C0C;">or </font><font style="color: #232323;">arrangement established as of the date of this Agreement, or as may subsequently be duly adopted for such purpose</font><font style="color: #606060;">, </font><font style="color: #232323;">by </font><font style="color: #343434;">a </font><font style="color: #232323;">majority of the non-employee members of the </font><font style="color: #343434;">Board of </font><font style="color: #0C0C0C;">Di</font><font style="color: #424242;">rec</font><font style="color: #232323;">tors or </font><font style="color: #343434;">a majority of </font><font style="color: #232323;">the </font><font style="color: #343434;">members </font><font style="color: #232323;">of </font><font style="color: #343434;">a committee of </font><font style="color: #232323;">non-employee directors established for such purpose for </font><font style="color: #343434;">services rendered </font><font style="color: #232323;">to the Company, (b) securities upon the exercise or exchange of or conversion of securities exercisable or exchangeable for or convertible </font><font style="color: #0C0C0C;">into </font><font style="color: #232323;">shares of Common
          Stock issued and outstanding on the date of this Agreement, provided that such securities have not been amended since the date of this Agreement </font><font style="color: #343434;">to </font><font style="color: #0C0C0C;">increase </font><font style="color: #232323;">the number of shares of Common Stock issuable upon exercise, exchange or conversion of such securities</font><font style="color: #343434;">&#160;</font><font style="color: #232323;">(other than in </font><font style="color: #424242;">connection </font><font style="color: #232323;">with </font><font style="color: #343434;">stock splits </font><font style="color: #232323;">or combinations)</font><font style="color: #343434;">, and </font><font style="color: #232323;">(c) securities issued pursuant to acquisitions </font><font style="color: #0C0C0C;">or </font><font style="color: #232323;">strategic transactions approved by a majority of the disinterested directors of the Company, other than a
          transaction </font><font style="color: #0E0E0E;">in </font><font style="color: #232323;">which the Company </font><font style="color: #0E0E0E;">is issuing </font><font style="color: #232323;">securities primarily </font><font style="color: #0E0E0E;">fo</font><font style="color: #383838;">r </font><font style="color: #232323;">the purpose of raising capital</font><font style="color: #383838;">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #606060;">&#8220;</font><font style="color: #232323;"><u>FCPA</u></font><font style="color: #4D4D4D;">&#8221; </font><font style="color: #232323;">means </font><font style="color: #383838;">the </font><font style="color: #4D4D4D;">Foreig</font><font style="color: #232323;">n </font><font style="color: #383838;">Corrupt Practices </font><font style="color: #232323;">Act </font><font style="color: #383838;">of </font><font style="color: #232323;">1977</font><font style="color: #606060;">, </font><font style="color: #383838;">as amended.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #383838;">&#8220;<u>FDA</u>&#8221; shall have the meaning ascribed to such term </font><font style="color: #232323;">in </font><font style="color: #383838;">Section 3.1(y).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #606060;">&#8220;</font><font style="color: #232323;"><u>FDCA</u></font><font style="color: #4D4D4D;">&#8221; </font><font style="color: #383838;">shall </font><font style="color: #232323;">have </font><font style="color: #383838;">the meani</font><font style="color: #0E0E0E;">ng </font><font style="color: #232323;">ascribed to such term </font><font style="color: #383838;">in </font><font style="color: #0E0E0E;">Section </font><font style="color: #232323;">3.1(y).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #232323;">&#8220;<u>GAAP</u>&#8221; </font><font style="color: #383838;">shall have the meaning ascribed </font><font style="color: #232323;">to </font><font style="color: #383838;">such </font><font style="color: #232323;">term </font><font style="color: #383838;">in Section 3.1(h).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #606060;">&#8220;</font><font style="color: #232323;"><u>Hazardous Materials</u>&#8221; </font><font style="color: #383838;">sha</font><font style="color: #0E0E0E;">ll </font><font style="color: #232323;">h</font><font style="color: #4D4D4D;">ave </font><font style="color: #232323;">the meaning assigned </font><font style="color: #383838;">to </font><font style="color: #232323;">such </font><font style="color: #0E0E0E;">te</font><font style="color: #383838;">rm </font><font style="color: #0E0E0E;">in </font><font style="color: #232323;">Section</font>&#160;<font style="color: #232323;">3.1(m).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #4D4D4D;">&#8220;</font><font style="color: #0E0E0E;"><u>Int</u></font><font style="color: #383838;"><u>el</u></font><font style="color: #0E0E0E;"><u>le</u></font><font style="color: #383838;"><u>ctual </u></font><font style="color: #232323;"><u>Property Rights</u></font><font style="color: #606060;">&#8221; </font><font style="color: #383838;">shal</font><font style="color: #0E0E0E;">l </font><font style="color: #383838;">have </font><font style="color: #4D4D4D;">th</font><font style="color: #232323;">e </font><font style="color: #383838;">meaning ascribed to </font><font style="color: #232323;">such term in</font>&#160;<font style="color: #232323;">Section 3.1(p).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #232323;">&#8220;<u>Liens</u></font><font style="color: #4D4D4D;">&#8221; </font><font style="color: #232323;">means a lien, charge, pledge, security </font><font style="color: #0E0E0E;">interest</font><font style="color: #383838;">, encumbra</font><font style="color: #0E0E0E;">nc</font><font style="color: #383838;">e, </font><font style="color: #232323;">right of first refusal</font><font style="color: #4D4D4D;">, </font><font style="color: #232323;">preemptive right or </font><font style="color: #383838;">other </font><font style="color: #232323;">restriction</font><font style="color: #606060;">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: rgb(56, 56, 56);">&#8220;<u>Material </u></font><font style="color: rgb(35, 35, 35);"><u>Adverse Effect</u>&#8221; shall mean any change, event, circumstance, development, condition, occurrence or effect that,
          individually or in the aggregate, (a) is materially adverse to the business, financial condition, properties, assets, liabilities, stockholders&#8217; equity or results of operations of the Company and its Subsidiaries, taken as a whole, or (b)
          materially delays or materially impairs the ability of the Company to comply, or prevents the Company from complying, with its obligations under this Agreement, the other Transaction Documents, or with respect to the Closing or would reasonably
          be expected to do so; <u>provided</u>, <u>however</u>, that none of the following will be deemed in themselves, either alone or in combination, to constitute, and that none of the following will be taken into account in determining whether
          there has been or will be, a Material Adverse Effect under subclause (a) of this definition:</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; color: #232323;">(i) any change generally affecting the economy, financial markets or political, economic or regulatory conditions in the United States or any other geographic region in which the Company conducts
        business, provided that the Company is not disproportionately affected thereby;</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; color: #232323;">(ii) general financial, credit or capital market conditions, including interest rates or exchange rates, or any changes therein, provided that the Company is not disproportionately affected thereby;</div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
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      </div>
      <div style="text-indent: 36pt; color: #232323;">(iii) any change that generally affects industries in which the Company and its Subsidiaries conduct business, provided that the Company is not disproportionately affected thereby;</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; color: #232323;">(iv) earthquakes, hurricanes, tsunamis, tornadoes, floods, mudslides, fires or other natural disasters, weather conditions, global pandemics, including the COVID-19 pandemic and related strains,
        epidemic or similar health emergency, and other force majeure events in the United States or any other location, provided that the Company is not disproportionately affected thereby;</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; color: #232323;">(v) national or international political or social conditions (or changes in such conditions), whether or not pursuant to the declaration of a national emergency or war, or the occurrence of any military
        or terrorist attack, provided that the Company is not disproportionately affected thereby;</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; color: #232323;">(vi) material changes in laws after the date of this Agreement; and</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; color: #232323;">(vii) in and of itself, any material failure by the Company to meet any published or internally prepared estimates of revenues, expenses, earnings or other economic performance for any period ending on
        or after the date of this Agreement (it being understood that the facts and circumstances giving rise to such failure may be deemed to constitute, and may be taken into account in determining whether there has been, a Material Adverse Effect to the
        extent that such facts and circumstances are not otherwise described in clauses (i)-(vi) of this definition).</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #606060;">&#8220;</font><font style="color: #232323;"><u>Material Permits</u></font><font style="color: #606060;">&#8221; </font><font style="color: #232323;">shall have the meaning ascribed to such </font><font style="color: #383838;">term </font><font style="color: #0E0E0E;">i</font><font style="color: #383838;">n </font><font style="color: #232323;">Section 3.1(n).</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #232323;">&#8220;<u>Person</u>&#8221; means an </font><font style="color: #0E0E0E;">ind</font><font style="color: #383838;">ividual </font><font style="color: #232323;">or corporation,
          partnership, trust, </font><font style="color: #0E0E0E;">incorporated </font><font style="color: #232323;">or unincorporated association, </font><font style="color: #383838;">joint </font><font style="color: #232323;">venture</font><font style="color: #606060;">, </font><font style="color: #0E0E0E;">l</font><font style="color: #383838;">imited </font><font style="color: #0E0E0E;">liability </font><font style="color: #232323;">company, joint stock company, government (or an
          agency or subdivision thereof) or other entity of any kind.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #232323;">&#8220;<u>Pharmaceutical Product</u></font><font style="color: #4D4D4D;">&#8221; </font><font style="color: #383838;">shall have </font><font style="color: #232323;">the </font><font style="color: #383838;">meaning ascribed to such tern in Section</font>&#160;<font style="color: #232323;">3.1(y).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; color: #232323;">&#8220;<u>Pre-Funded Warrant Shares</u>&#8221; means the shares of Common Stock issuable upon exercise of the Pre-Funded Warrants.</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; color: #232323;">&#8220;<u>Pre-Funded Warrants</u>&#8221; means, collectively, the Common Stock purchase warrants delivered to the Purchasers at the Closing in accordance with Section 2.2(a) hereof, which shall be in the form of <u>Exhibit






          A</u> attached hereto.</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #232323;">&#8220;<u>Proceeding</u></font><font style="color: #606060;">&#8221; </font><font style="color: #232323;">means </font><font style="color: #383838;">an act</font><font style="color: #0E0E0E;">ion, </font><font style="color: #232323;">claim</font><font style="color: #4D4D4D;">, </font><font style="color: #383838;">suit, invest</font><font style="color: #0E0E0E;">igation </font><font style="color: #232323;">or proceeding.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #3F3F3F;">&#8220;<u>Prospec</u></font><font style="color: #151515;"><u>tus</u></font><font style="color: #525252;">&#8221; </font><font style="color: #282828;">means </font><font style="color: #3F3F3F;">the </font><font style="color: #282828;">base prospectus </font><font style="color: #3F3F3F;">i</font><font style="color: #151515;">ncluded in </font><font style="color: #282828;">the Registration Statement.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #282828;">&#8220;<u>Prospectus </u></font><font style="color: #151515;"><u>Supplement</u></font><font style="color: #525252;">&#8221; </font><font style="color: #282828;">means the </font><font style="color: #3F3F3F;">supplement </font><font style="color: #282828;">to the Prospectus complying </font><font style="color: #3F3F3F;">with </font><font style="color: #282828;">Rule 424(b) of </font><font style="color: #151515;">the </font><font style="color: #282828;">Securities </font><font style="color: #151515;">Act </font><font style="color: #282828;">that will</font><font style="font-weight: bold; color: #282828;">&#160;</font><font style="color: #282828;">be </font><font style="color: #151515;">filed </font><font style="color: #282828;">with the Commission in connection with the offer and </font><font style="color: #151515;">sale </font><font style="color: #282828;">of </font><font style="color: #151515;">the
        </font><font style="color: #282828;">Pre-Funded Warrants, Pre-Funded Warrant Shares and Shares.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #282828;">&#8220;<u>Purchaser Material Adverse Effect</u>&#8221; means, with respect to any Purchaser, </font><font style="color: #232323;">any change, event, circumstance, development,
          condition, occurrence or effect that, individually or in the aggregate, materially delays or materially impairs the ability of such Purchaser to comply, or prevents such Purchaser from complying, with its obligations under this Agreement, the
          other Transaction Documents, or with respect to the Closing or would reasonably be expected to do so.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #525252;">&#8220;</font><font style="color: #282828;"><u>Registration </u></font><font style="color: #151515;"><u>Statement</u></font><font style="color: #525252;">&#8221; </font><font style="color: #282828;">means the </font><font style="color: #3F3F3F;">effective </font><font style="color: #282828;">shelf registration </font><font style="color: #151515;">statement </font><font style="color: #282828;">on Form</font>&#160;<font style="color: #282828;">S-3 on file with Commission (File </font><font style="color: #151515;">No. </font><font style="color: #282828;">333-</font>&#160;<font style="color: #282828;">276462), as amended from time to time, which </font><font style="color: #151515;">registers the </font><font style="color: #282828;">sale </font><font style="color: #151515;">of </font><font style="color: #282828;">the Pre-Funded Warrants, Pre-Funded Warrant Shares and Shares to the </font><font style="color: #151515;">Purchas</font><font style="color: #3F3F3F;">ers.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #3F3F3F;">&#8220;</font><font style="color: #151515;"><u>Required Approvals</u></font><font style="color: #3F3F3F;">&#8221; </font><font style="color: #282828;">shall have the meaning
          ascribed </font><font style="color: #151515;">to </font><font style="color: #282828;">such </font><font style="color: #151515;">term in Section</font>&#160;<font style="color: #282828;">3.1(e).</font></div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #3F3F3F;">&#8220;<u>Rule </u></font><font style="color: #282828;"><u>144</u></font><font style="color: #6E6E6E;">&#8221; </font><font style="color: #151515;">means </font><font style="color: #282828;">Rule 144 promulgated by the Commission pursuant to </font><font style="color: #3F3F3F;">the</font>&#160;<font style="color: #151515;">Securities Act</font><font style="color: #3F3F3F;">, </font><font style="color: #282828;">as






          such </font><font style="color: #151515;">Rule </font><font style="color: #282828;">may be amended or </font><font style="color: #151515;">interpreted </font><font style="color: #282828;">from time to </font><font style="color: #151515;">time</font><font style="color: #3F3F3F;">, </font><font style="color: #282828;">or any similar rule </font><font style="color: #151515;">or regulation </font><font style="color: #282828;">hereafter adopted by </font><font style="color: #3F3F3F;">the </font><font style="color: #282828;">Commission having substantially </font><font style="color: #151515;">the </font><font style="color: #282828;">same </font><font style="color: #151515;">purpose </font><font style="color: #282828;">and effect as such
          Rule.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #3F3F3F;">&#8220;</font><font style="color: #151515;"><u>Rule </u></font><font style="color: #282828;"><u>424</u></font><font style="color: #7C7C7C;">&#8221; </font><font style="color: #282828;">means Rule </font><font style="color: #3F3F3F;">424 </font><font style="color: #282828;">promulga</font><font style="color: #525252;">ted </font><font style="color: #282828;">by the </font><font style="color: #3F3F3F;">Comm</font><font style="color: #151515;">i</font><font style="color: #3F3F3F;">ss</font><font style="color: #151515;">i</font><font style="color: #3F3F3F;">on </font><font style="color: #282828;">pursuant to the </font><font style="color: #151515;">Securities
          Act</font><font style="color: #525252;">, </font><font style="color: #282828;">as such </font><font style="color: #151515;">Rule </font><font style="color: #282828;">may </font><font style="color: #151515;">be </font><font style="color: #282828;">amended </font><font style="color: #151515;">or interpreted </font><font style="color: #282828;">from time to time</font><font style="color: #525252;">, </font><font style="color: #151515;">or </font><font style="color: #282828;">any






          similar rule </font><font style="color: #151515;">or regulation </font><font style="color: #282828;">hereafter adopted by the Commission having substantially </font><font style="color: #151515;">the </font><font style="color: #282828;">same
          purpose and effect as such Rule</font><font style="color: #525252;">.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #3F3F3F;">&#8220;<u>S</u></font><font style="color: #151515;"><u>EC Reports</u></font><font style="color: #525252;">&#8221; </font><font style="color: #282828;">shall </font><font style="color: #151515;">have </font><font style="color: #282828;">the meaning ascribed </font><font style="color: #151515;">to such </font><font style="color: #282828;">te</font><font style="color: #525252;">r</font><font style="color: #282828;">m </font><font style="color: #151515;">in </font><font style="color: #282828;">Section 3.1(h).</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt; color: #282828;">&#8220;<u>Securities</u>&#8221; means the Shares, the Pre-Funded Warrants, and the Pre-Funded Warrant Shares.</div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #3F3F3F;">&#8220;<u>Secur</u></font><font style="color: #151515;"><u>iti</u></font><font style="color: #3F3F3F;"><u>es </u></font><font style="color: #151515;"><u>Act</u></font><font style="color: #525252;">&#8221; </font><font style="color: #282828;">means the Securities </font><font style="color: #151515;">A</font><font style="color: #3F3F3F;">ct </font><font style="color: #282828;">of 1933, as amended, </font><font style="color: #3F3F3F;">and </font><font style="color: #282828;">the rules </font><font style="color: #3F3F3F;">and</font>&#160;<font style="color: #282828;">regulations promulgated </font><font style="color: #151515;">thereu</font><font style="color: #3F3F3F;">nder.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #282828;">&#8220;<u>Shares</u>&#8221; means </font><font style="color: #151515;">the </font><font style="color: #282828;">shares </font><font style="color: #151515;">of Common </font><font style="color: #282828;">Stock </font><font style="color: #151515;">issued or </font><font style="color: #282828;">issuable to each </font><font style="color: #151515;">Purchaser </font><font style="color: #282828;">pursuant to this </font><font style="color: #151515;">Agreement.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #3F3F3F;">&#8220;</font><font style="color: #151515;"><u>Short Sales</u></font><font style="color: #525252;">&#8221; </font><font style="color: #282828;">means all </font><font style="color: #3F3F3F;">&#8220;short sales&#8221; </font><font style="color: #282828;">a</font><font style="color: #525252;">s </font><font style="color: #282828;">d</font><font style="color: #525252;">efi</font><font style="color: #282828;">ned </font><font style="color: #3F3F3F;">in </font><font style="color: #282828;">Rule 200 </font><font style="color: #3F3F3F;">of </font><font style="color: #282828;">R</font><font style="color: #525252;">e</font><font style="color: #282828;">gulation SHO
          under the Exchange Act </font><font style="color: #151515;">(but </font><font style="color: #282828;">shall not </font><font style="color: #151515;">be </font><font style="color: #282828;">deemed </font><font style="color: #151515;">to </font><font style="color: #282828;">include </font><font style="color: #151515;">locating </font><font style="color: #282828;">and/or borrowing shares </font><font style="color: #151515;">of Common </font><font style="color: #282828;">Stock).</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #525252;">&#8220;</font><font style="color: #151515;"><u>Subscription Amount</u>&#8221; means</font><font style="color: #3F3F3F;">, </font><font style="color: #282828;">as to each
          Purchaser, the aggregate amount to </font><font style="color: #151515;">be </font><font style="color: #282828;">paid </font><font style="color: #151515;">for Securities </font><font style="color: #282828;">purchased hereunder </font><font style="color: #3F3F3F;">as specified </font><font style="color: #282828;">below </font><font style="color: #3F3F3F;">such </font><font style="color: #282828;">Purchaser's name on </font><font style="color: #3F3F3F;">the signature </font><font style="color: #282828;">page of </font><font style="color: #3F3F3F;">this Agreement and </font><font style="color: #282828;">ne</font><font style="color: #525252;">x</font><font style="color: #282828;">t to </font><font style="color: #3F3F3F;">the






        </font><font style="color: #282828;">headin</font><font style="color: #525252;">g &#8220;</font><font style="color: #282828;">Subscription </font><font style="color: #3F3F3F;">Amount</font><font style="color: #6E6E6E;">,</font><font style="color: #525252;">&#8221; </font><font style="color: #151515;">in United </font><font style="color: #282828;">States dollars </font><font style="color: #3F3F3F;">and </font><font style="color: #151515;">in immediately </font><font style="color: #282828;">available






        </font><font style="color: #151515;">fund</font><font style="color: #3F3F3F;">s.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #3F3F3F;">&#8220;</font><font style="color: #151515;"><u>Subsidiary</u></font><font style="color: #525252;">&#8221; </font><font style="color: #151515;">means </font><font style="color: #282828;">any subsidiary of </font><font style="color: #151515;">the Company </font><font style="color: #282828;">as set </font><font style="color: #151515;">forth in the SEC </font><font style="color: #282828;">Reports</font><font style="color: #525252;">, </font><font style="color: #282828;">and shall</font><font style="color: #6E6E6E;">, </font><font style="color: #282828;">where applicable</font><font style="color: #6E6E6E;">, </font><font style="color: #282828;">also






        </font><font style="color: #151515;">include </font><font style="color: #282828;">any direct o</font><font style="color: #525252;">r </font><font style="color: #151515;">indirect </font><font style="color: #282828;">subsidiary of the Company
          formed o</font><font style="color: #525252;">r </font><font style="color: #282828;">acquired after the date hereof.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #4F4F4F;">&#8220;<u>Trading </u></font><font style="color: #212121;"><u>Day</u></font><font style="color: #4F4F4F;">&#8221;</font><font style="color: #212121;"> means a day on which the p</font><font style="color: #4F4F4F;">r</font><font style="color: #0C0C0C;">i</font><font style="color: #343434;">ncipal </font><font style="color: #212121;">Trading Market </font><font style="color: #343434;">is </font><font style="color: #212121;">open
          for trading.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #343434;">&#8220;<u>Trading </u></font><font style="color: #212121;"><u>Market</u></font><font style="color: #4F4F4F;">&#8221; </font><font style="color: #343434;">means </font><font style="color: #212121;">any of the </font><font style="color: #0C0C0C;">following </font><font style="color: #212121;">markets or exchanges on which </font><font style="color: #343434;">the </font><font style="color: #212121;">Common Stock is
          listed or quoted for trading on </font><font style="color: #343434;">the </font><font style="color: #212121;">date in question</font><font style="color: #4F4F4F;">: </font><font style="color: #212121;">the NYSE American, the Nasdaq Capital
          Market, the Nasdaq Global Market, the Nasdaq Global Select Market, the New York Stock Exchange, OTCQB or OTCQX (or any successors to any of the foregoing)</font><font style="color: #4F4F4F;">.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #4F4F4F;">&#8220;<u>Transaction </u></font><font style="color: #212121;"><u>Documents</u></font><font style="color: #4F4F4F;">&#8221; </font><font style="color: #212121;">means this
          Agreement</font><font style="color: #4F4F4F;">, </font><font style="color: #212121;">all exhibits and schedules thereto and hereto and any </font><font style="color: #0C0C0C;">other </font><font style="color: #212121;">documents or </font><font style="color: #343434;">agreements </font><font style="color: #212121;">executed with </font><font style="color: #343434;">the </font><font style="color: #0C0C0C;">Purchasers </font><font style="color: #343434;">in </font><font style="color: #212121;">connection with the transactions contemplated hereunder.</font></div>
      <div><br>
      </div>
      <div style="text-align: justify; text-indent: 36pt;"><font style="color: #626262;">&#8220;</font><font style="color: #343434;"><u>Transfer </u></font><font style="color: #212121;"><u>Agent</u></font><font style="color: #626262;">&#8221; </font><font style="color: #212121;">means Equiniti Trust Company, LLC, the current transfer agent of the Company, and any successor transfer agent of the Company.</font></div>
      <div><br>
      </div>
      <div style="text-align: center; color: #212121;">ARTICLE II.</div>
      <div style="text-align: center;"><font style="color: #343434;">PURCHASE </font><font style="color: #0C0C0C;">AND </font><font style="color: #212121;">SALE</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(33, 33, 33);">2.1</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(33, 33, 33);"><u>Closing</u>. On the Closing Date</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(33, 33, 33);">upon the terms </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(33, 33, 33);">subject to the </font><font style="color: rgb(52, 52, 52);">conditions </font><font style="color: rgb(33, 33, 33);">set forth here</font><font style="color: rgb(79, 79, 79);">i</font><font style="color: rgb(12, 12, 12);">n</font><font style="color: rgb(52, 52, 52);">, </font><font style="color: rgb(33, 33, 33);">the Company agrees to sell,
          and the </font><font style="color: rgb(52, 52, 52);">Purchasers, </font><font style="color: rgb(33, 33, 33);">severally and not jointly</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(33, 33, 33);">agree to
          purchase the number of Shares, at a price per Share of $2.09, and Pre-Funded Warrants, at a price per Pre-Funded Warrant of $2.0899, in each case, set forth on the signature page hereto executed by such Purchaser. Each Purchaser</font><font style="color: rgb(79, 79, 79);">'</font><font style="color: rgb(52, 52, 52);">s </font><font style="color: rgb(33, 33, 33);">Subscription Amount </font><font style="color: rgb(52, 52, 52);">as </font><font style="color: rgb(33, 33, 33);">set
          forth on the signature page </font><font style="color: rgb(52, 52, 52);">hereto </font><font style="color: rgb(33, 33, 33);">executed by such Purchaser shall be made </font><font style="color: rgb(52, 52, 52);">available for </font><font style="color: rgb(79, 79, 79);">&#8220;</font><font style="color: rgb(33, 33, 33);">Deliver</font><font style="color: rgb(79, 79, 79);">y </font><font style="color: rgb(52, 52, 52);">Versus </font><font style="color: rgb(33, 33, 33);">Payment</font><font style="color: rgb(79, 79, 79);">&#8221; </font><font style="color: rgb(52, 52, 52);">settlement with the Company </font><font style="color: rgb(33, 33, 33);">or </font><font style="color: rgb(12, 12, 12);">its </font><font style="color: rgb(33, 33, 33);">designee. </font><font style="color: rgb(12, 12, 12);">The </font><font style="color: rgb(33, 33, 33);">Company </font><font style="color: rgb(52, 52, 52);">shall </font><font style="color: rgb(33, 33, 33);">deliver to each </font><font style="color: rgb(52, 52, 52);">Purchaser </font><font style="color: rgb(12, 12, 12);">its </font><font style="color: rgb(33, 33, 33);">respective Shares and </font><font style="color: rgb(40, 40, 40);">Pre-Funded</font><font style="color: rgb(33, 33, 33);"> Warrants</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(33, 33, 33);">and </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(33, 33, 33);">Company </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(33, 33, 33);">each Purchaser </font><font style="color: rgb(52, 52, 52);">shall </font><font style="color: rgb(33, 33, 33);">deliver the other </font><font style="color: rgb(52, 52, 52);">items set forth </font><font style="color: rgb(33, 33, 33);">in Section 2</font><font style="color: rgb(79, 79, 79);">.</font><font style="color: rgb(33, 33, 33);">2, </font><font style="color: rgb(52, 52, 52);">at </font><font style="color: rgb(33, 33, 33);">the Closing</font><font style="color: rgb(79, 79, 79);">. </font><font style="color: rgb(33, 33, 33);">Upon </font><font style="color: rgb(52, 52, 52);">satisfaction </font><font style="color: rgb(33, 33, 33);">of





        </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(33, 33, 33);">covenants </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(33, 33, 33);">conditions se</font><font style="color: rgb(79, 79, 79);">t </font><font style="color: rgb(52, 52, 52);">forth </font><font style="color: rgb(33, 33, 33);">in Sections 2.2 and 2.3</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(33, 33, 33);">the Closing </font><font style="color: rgb(52, 52, 52);">shall </font><font style="color: rgb(33, 33, 33);">occur at the offices of the Company or </font><font style="color: rgb(52, 52, 52);">such </font><font style="color: rgb(33, 33, 33);">other </font><font style="color: rgb(12, 12, 12);">location </font><font style="color: rgb(33, 33, 33);">as the parties shall mutually agree. Settlement of the Shares </font><font style="color: rgb(52, 52, 52);">shall occur </font><font style="color: rgb(79, 79, 79);">via </font><font style="color: rgb(52, 52, 52);">&#8220;Delivery Versus </font><font style="color: rgb(33, 33, 33);">Paymen</font><font style="color: rgb(98, 98, 98);">t</font><font style="color: rgb(52, 52, 52);">&#8221; (i.e., on the Closing </font><font style="color: rgb(33, 33, 33);">Date</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(33, 33, 33);">Company </font><font style="color: rgb(52, 52, 52);">shall </font><font style="color: rgb(12, 12, 12);">issue </font><font style="color: rgb(33, 33, 33);">the </font><font style="color: rgb(52, 52, 52);">Shares in book entry form registered in the Purchasers' </font><font style="color: rgb(33, 33, 33);">name
          released by </font><font style="color: rgb(12, 12, 12);">the </font><font style="color: rgb(52, 52, 52);">Transfer </font><font style="color: rgb(33, 33, 33);">Agent di</font><font style="color: rgb(79, 79, 79);">r</font><font style="color: rgb(52, 52, 52);">ect</font><font style="color: rgb(12, 12, 12);">ly </font><font style="color: rgb(33, 33, 33);">to the </font><font style="color: rgb(52, 52, 52);">account(s) </font><font style="color: rgb(33, 33, 33);">identified by </font><font style="color: rgb(52, 52, 52);">each </font><font style="color: rgb(33, 33, 33);">Purchaser following receipt of payment therefor </font><font style="color: rgb(52, 52, 52);">by the </font><font style="color: rgb(33, 33, 33);">Company which
          shall be </font><font style="color: rgb(52, 52, 52);">made </font><font style="color: rgb(33, 33, 33);">by each Purchaser by wire transfer to </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(33, 33, 33);">Company).</font></div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #343434;">2.2</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #212121;"><u>Deliveries</u></font><font style="color: #4F4F4F;">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(33, 33, 33);">(a)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(33, 33, 33);">On or </font><font style="color: rgb(52, 52, 52);">prior </font><font style="color: rgb(33, 33, 33);">to the Closing Date, </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(33, 33, 33);">Company </font><font style="color: rgb(52, 52, 52);">shall </font><font style="color: rgb(33, 33, 33);">deliver or cause
          to be delivered </font><font style="color: rgb(52, 52, 52);">to each </font><font style="color: rgb(33, 33, 33);">Purchaser the following:</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt; text-align: justify;"><font style="color: rgb(33, 33, 33);">(i)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(33, 33, 33);">this Agreement duly executed by the Company</font><font style="color: rgb(79, 79, 79);">;</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt; text-align: justify;"><font style="color: rgb(33, 33, 33);">(ii)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(33, 33, 33);">the </font><font style="color: rgb(52, 52, 52);">Company's </font><font style="color: rgb(33, 33, 33);">wire</font><font style="font-weight: bold; color: rgb(33, 33, 33);">&#160;</font><font style="color: rgb(33, 33, 33);">instructions</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(33, 33, 33);">on Company </font><font style="color: rgb(52, 52, 52);">letterhead </font><font style="color: rgb(33, 33, 33);">and executed by the Chief Executive Officer or Chief </font><font style="color: rgb(52, 52, 52);">Financial </font><font style="color: rgb(33, 33, 33);">Officer</font><font style="color: rgb(79, 79, 79);">;</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt; text-align: justify;"><font style="color: rgb(33, 33, 33);">(iii)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(33, 33, 33);">a copy </font><font style="color: rgb(52, 52, 52);">of </font><font style="color: rgb(33, 33, 33);">the irrevocable </font><font style="color: rgb(52, 52, 52);">instructions </font><font style="color: rgb(33, 33, 33);">to the Transfer Agent </font><font style="color: rgb(12, 12, 12);">ins</font><font style="color: rgb(79, 79, 79);">t</font><font style="color: rgb(52, 52, 52);">ruct</font><font style="color: rgb(12, 12, 12);">ing </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(33, 33, 33);">Transfer Agent </font><font style="color: rgb(52, 52, 52);">to
          deliver </font><font style="color: rgb(33, 33, 33);">on </font><font style="color: rgb(52, 52, 52);">an expedited </font><font style="color: rgb(33, 33, 33);">basis</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(33, 33, 33);">via </font><font style="color: rgb(52, 52, 52);">The </font><font style="color: rgb(33, 33, 33);">Depository </font><font style="color: rgb(52, 52, 52);">Trust </font><font style="color: rgb(33, 33, 33);">Company Deposit or
          Withdrawal at Custodian system, </font><font style="color: rgb(35, 35, 35);">Shares </font><font style="color: rgb(54, 54, 54);">equal </font><font style="color: rgb(35, 35, 35);">to </font><font style="color: rgb(54, 54, 54);">the number of
          shares as set forth on the signature page of such Purchaser</font><font style="color: rgb(35, 35, 35);">;</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(iv)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(35, 35, 35);">a </font><font style="color: rgb(40, 40, 40);">Pre-Funded</font><font style="color: rgb(35, 35, 35);"> Warrant registered in the name of such Purchaser to purchase up to a number of shares of Common Stock </font><font style="color: rgb(54, 54, 54);">as set forth on the signature page of such Purchaser</font><font style="color: rgb(35, 35, 35);">, in the form of <u>Exhibit A</u> attached hereto; and</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt;"><font style="color: #232323;">(v)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #232323;">the Prospectus and the </font><font style="color: #363636;">Prospectus Supplement </font><font style="color: #232323;">(which may be
          delivered </font><font style="color: #0E0E0E;">in </font><font style="color: #232323;">accordance with Rule </font><font style="color: #0E0E0E;">172 </font><font style="color: #232323;">under the Securities </font><font style="color: #0E0E0E;">Act)</font><font style="color: #545454;">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt;"><font style="color: #232323;">(b)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: #232323;">On or prior </font><font style="color: #0E0E0E;">to </font><font style="color: #232323;">the Closing Date</font><font style="color: #545454;">, </font><font style="color: #232323;">each Purchaser shall deliver or cause to be delivered to the Company the </font><font style="color: #363636;">following:</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt;"><font style="color: #232323;">(i)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: #232323;">this Agreement duly executed by such Purchaser</font><font style="color: #545454;">; </font><font style="color: #232323;">and</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt;"><font style="color: #232323;">(ii)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #232323;">such Purchaser</font><font style="color: #545454;">'</font><font style="color: #232323;">s Subscription Amount</font><font style="color: #545454;">, </font><font style="color: #232323;">which shall be made </font><font style="color: #363636;">available for </font><font style="color: #545454;">&#8220;Delivery </font><font style="color: #363636;">Versus Payment&#8221; settlement </font><font style="color: #232323;">with the Company </font><font style="color: #363636;">or </font><font style="color: #232323;">its designee.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt;"><font style="color: #232323;">(c)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: #232323;">Secretary&#8217;s Certificate. At the Closing, each of the Purchasers shall have received a certificate signed by the Secretary of the Company,
          in form and substance reasonably satisfactory to the Purchasers, certifying as to (i) the resolutions of the Board of Directors of the Company or a duly authorized committee thereof approving this Agreement and all of the transactions
          contemplated hereunder, (ii) its Certificate of Incorporation, (iii) its Bylaws, and (iv) the good standing of the Company in the State of Delaware (as evidenced by certificates obtained from such jurisdictions dated within five (5) Business Days
          of the date hereof).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt;"><font style="color: #232323;">(d)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: #232323;">Compliance Certificate. At the Closing, each of the Purchasers shall have received a certificate, in form and substance reasonably
          satisfactory to the Purchasers, signed by the Chief Executive Officer of the Company certifying to the fulfillment of the conditions set forth in Section 2.3(a).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt;"><font style="color: #232323;">2.3</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #232323;"><u>Closing Conditions</u>.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt;"><font style="color: #232323;">(a)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: #232323;">The obligations of the Company </font><font style="color: #363636;">hereunder </font><font style="color: #0E0E0E;">in </font><font style="color: #232323;">connection with the Closing are </font><font style="color: #363636;">subject </font><font style="color: #232323;">to the following conditions being </font><font style="color: #363636;">met:</font></div>
      <div style="text-indent: 72pt;"><font style="color: #363636;"> <br>
        </font></div>
      <div style="text-indent: 72pt;">
        <div style="text-indent: 108pt;"><font style="color: #232323;">(i)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: #232323;">the accuracy </font><font style="color: #0E0E0E;">in </font><font style="color: #232323;">all material respects </font><font style="color: #363636;">(or, </font><font style="color: #232323;">to </font><font style="color: #363636;">the </font><font style="color: #232323;">extent representations or warranties are qualified by materiality or Purchaser Material
            Adverse Effect</font><font style="color: #545454;">, </font><font style="color: #0E0E0E;">in </font><font style="color: #232323;">all respects) on the Closing Date of the representations and warranties of the </font><font style="color: #0E0E0E;">Purchasers </font><font style="color: #232323;">contained herein (unless </font><font style="color: #363636;">as </font><font style="color: #232323;">of a specific date therein in which case they shall be accurate as of such date);</font></div>
        <div><br>
        </div>
        <div style="text-indent: 108pt;"><font style="color: #232323;">(ii)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #232323;">the obligations, covenants and agreements of each </font><font style="color: #0E0E0E;">Purchaser </font><font style="color: #363636;">required to be </font><font style="color: #232323;">performed at or prior to the Closing Date shal</font><font style="color: #0E0E0E;">l </font><font style="color: #232323;">have been performed in all material respects; and</font></div>
        <div><br>
        </div>
        <div style="text-indent: 108pt;"><font style="color: #232323;">(iii)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #232323;">the delivery by each Purchaser of the items set forth </font><font style="color: #0E0E0E;">in </font><font style="color: #232323;">Section






            2.2(b) of this Agreement.</font></div>
        <div style="text-indent: 108pt;"><br>
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            <div class="BRPFPageBreak" style="page-break-after: always;">
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          </div>
        </div>
      </div>
      <div style="text-indent: 72pt;"><font style="color: #232323;">(b)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: #232323;">The respective obl</font><font style="color: #0E0E0E;">igations </font><font style="color: #232323;">of the Purchasers hereunder in </font><font style="color: #363636;">connection </font><font style="color: #232323;">with </font><font style="color: #363636;">the </font><font style="color: #232323;">Closing </font><font style="color: #363636;">are </font><font style="color: #232323;">subject






          to </font><font style="color: #363636;">the </font><font style="color: #232323;">following conditions being met:</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt;"><font style="color: #232323;">(i)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: #232323;">the accuracy </font><font style="color: #0E0E0E;">in </font><font style="color: #232323;">all material respects </font><font style="color: #363636;">(or, </font><font style="color: #232323;">to </font><font style="color: #363636;">the </font><font style="color: #232323;">extent representations or warranties are qualified by </font><font style="color: #363636;">materiality






        </font><font style="color: #232323;">or </font><font style="color: #363636;">Material </font><font style="color: #232323;">Adverse Effect, in all respects) when made and </font><font style="color: #0E0E0E;">on </font><font style="color: #232323;">the Closing Date of the representations and warranties of the Company contained </font><font style="color: #0E0E0E;">herein </font><font style="color: #232323;">(unless as of a specific date therein </font><font style="color: #0E0E0E;">in </font><font style="color: #232323;">which case they shall be </font><font style="color: #363636;">accurate </font><font style="color: #232323;">as of such date);</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt;"><font style="color: #232323;">(ii)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #232323;">the obligations, covenants and agreements of<font style="font-weight: bold;">&#160;</font>the Company required to be performed at or prior to
          the Closing Date shall have been performed in all material respects;</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt;"><font style="color: #232323;">(iii)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #232323;">the delivery by the Company of the </font><font style="color: #363636;">items </font><font style="color: #232323;">set forth in
          Section 2</font><font style="color: #545454;">.</font><font style="color: #232323;">2(a) of this </font><font style="color: #0E0E0E;">Agreement;</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt;"><font style="color: #262626;">(iv)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: #262626;">there shall </font><font style="color: #111111;">have </font><font style="color: #262626;">been no Material </font><font style="color: #111111;">Adverse </font><font style="color: #262626;">Effect with respect to the </font><font style="color: #111111;">Company </font><font style="color: #262626;">since the date hereof that is continuing; and</font></div>
      <div><br>
      </div>
      <div style="text-indent: 108pt;"><font style="color: #262626;">(v)</font>&#160;&#160;&#160;&#160;&#160;&#160; &#160; <font style="color: #262626;">from the date hereof to the Closing Date, trading </font><font style="color: #111111;">in </font><font style="color: #262626;">the
          Common Stock shall not have been suspended by the Commission or the Company's principal Trading Market.</font></div>
      <div><br>
      </div>
      <div style="text-align: center;"><font style="color: #111111;">ARTICLE </font><font style="color: #262626;">III.</font></div>
      <div style="text-align: center;"><font style="color: #262626;">REPRESENTATIONS </font><font style="color: #111111;">AND </font><font style="color: #262626;">WARRANTIES</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">3.1</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(38, 38, 38);"><u>Representations and Warranties of the Company</u>. Except as set </font><font style="color: rgb(17, 17, 17);">forth </font><font style="color: rgb(38, 38, 38);">in the SEC Reports, which SEC Reports shall be deemed a part hereof and shall qualify any representation or otherwise made herein, the Company hereby </font><font style="color: rgb(17, 17, 17);">makes </font><font style="color: rgb(38, 38, 38);">the following representations and warranties to each </font><font style="color: rgb(17, 17, 17);">Purchaser:</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(a)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(38, 38, 38);"><u>Subsidiaries</u>. </font><font style="color: rgb(17, 17, 17);">All</font><font style="font-weight: bold; color: rgb(17, 17, 17);">&#160;</font><font style="color: rgb(38, 38, 38);">of the direct and </font><font style="color: rgb(17, 17, 17);">indirect </font><font style="color: rgb(38, 38, 38);">subsidiaries of the Company
          are set forth </font><font style="color: rgb(17, 17, 17);">in </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(17, 17, 17);">SEC </font><font style="color: rgb(38, 38, 38);">Reports. Except as set forth in the
          SEC Reports, the Company owns, directly or </font><font style="color: rgb(17, 17, 17);">indirectly, </font><font style="color: rgb(38, 38, 38);">all of </font><font style="color: rgb(17, 17, 17);">the </font><font style="color: rgb(38, 38, 38);">capital stock or other equity interests of each </font><font style="color: rgb(17, 17, 17);">Subsidiary </font><font style="color: rgb(38, 38, 38);">free and clear </font><font style="color: rgb(17, 17, 17);">of </font><font style="color: rgb(38, 38, 38);">any </font><font style="color: rgb(17, 17, 17);">Liens</font><font style="color: rgb(73, 73, 73);">, </font><font style="color: rgb(38, 38, 38);">and all of the </font><font style="color: rgb(17, 17, 17);">issued





        </font><font style="color: rgb(38, 38, 38);">and outstanding shares </font><font style="color: rgb(17, 17, 17);">of </font><font style="color: rgb(38, 38, 38);">capital stock of each Subsidiary are validly issued and are </font><font style="color: rgb(17, 17, 17);">fully </font><font style="color: rgb(38, 38, 38);">paid, non-assessable and free of preemptive and similar rights to subscribe for or purchase securities.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(b)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(17, 17, 17);"><u>Organization </u></font><font style="color: rgb(38, 38, 38);"><u>and Qualification</u>. </font><font style="color: rgb(17, 17, 17);">The </font><font style="color: rgb(38, 38, 38);">Company and each </font><font style="color: rgb(17, 17, 17);">of</font><font style="font-weight: bold; color: rgb(17, 17, 17);">&#160;</font><font style="color: rgb(38, 38, 38);">the Subsidiaries </font><font style="color: rgb(17, 17, 17);">is </font><font style="color: rgb(38, 38, 38);">an </font><font style="color: rgb(17, 17, 17);">entity </font><font style="color: rgb(38, 38, 38);">duly </font><font style="color: rgb(17, 17, 17);">incorporated </font><font style="color: rgb(38, 38, 38);">or otherwise organized</font><font style="color: rgb(93, 93, 93);">, </font><font style="color: rgb(38, 38, 38);">validly existing and </font><font style="color: rgb(17, 17, 17);">in </font><font style="color: rgb(38, 38, 38);">good standing </font><font style="color: rgb(17, 17, 17);">under </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(17, 17, 17);">laws





        </font><font style="color: rgb(38, 38, 38);">of the jurisdiction of </font><font style="color: rgb(17, 17, 17);">i</font><font style="color: rgb(73, 73, 73);">t</font><font style="color: rgb(38, 38, 38);">s </font><font style="color: rgb(17, 17, 17);">incorporation </font><font style="color: rgb(38, 38, 38);">or organization, with the </font><font style="color: rgb(73, 73, 73);">requisite </font><font style="color: rgb(38, 38, 38);">power and authority to own and use </font><font style="color: rgb(17, 17, 17);">its </font><font style="color: rgb(38, 38, 38);">properties and assets and to carry on </font><font style="color: rgb(17, 17, 17);">its </font><font style="color: rgb(38, 38, 38);">business as currently
          conducted. Neither the Company nor any Subsidiary </font><font style="color: rgb(17, 17, 17);">is in </font><font style="color: rgb(38, 38, 38);">violation nor default of any of the provisions of its </font><font style="color: rgb(17, 17, 17);">respective </font><font style="color: rgb(38, 38, 38);">certificate or articles of </font><font style="color: rgb(17, 17, 17);">incorporation, </font><font style="color: rgb(38, 38, 38);">bylaws </font><font style="color: rgb(17, 17, 17);">or other </font><font style="color: rgb(38, 38, 38);">organizational or charter </font><font style="color: rgb(17, 17, 17);">documents. Each </font><font style="color: rgb(38, 38, 38);">of the Company and the Subsidiaries is duly </font><font style="color: rgb(17, 17, 17);">qualified </font><font style="color: rgb(38, 38, 38);">to conduct business and </font><font style="color: rgb(17, 17, 17);">is in </font><font style="color: rgb(38, 38, 38);">good standing as a </font><font style="color: rgb(17, 17, 17);">foreign </font><font style="color: rgb(38, 38, 38);">corporation or other entity in each </font><font style="color: rgb(17, 17, 17);">jurisdiction </font><font style="color: rgb(38, 38, 38);">in which the nature
          of the business conducted or property owned by it makes </font><font style="color: rgb(17, 17, 17);">such </font><font style="color: rgb(38, 38, 38);">qualification necessary, except where the failure to be so qualified or in good standing, as
        </font><font style="color: rgb(17, 17, 17);">the </font><font style="color: rgb(38, 38, 38);">case may be, would </font><font style="color: rgb(17, 17, 17);">not reasonably </font><font style="color: rgb(38, 38, 38);">be expected to </font><font style="color: rgb(17, 17, 17);">result in </font><font style="color: rgb(38, 38, 38);">a Material Adverse Effect and no Proceeding has been </font><font style="color: rgb(19, 19, 19);">institu</font><font style="color: rgb(66, 66, 66);">t</font><font style="color: rgb(38, 38, 38);">ed in any </font><font style="color: rgb(66, 66, 66);">s</font><font style="color: rgb(19, 19, 19);">uch jurisdiction </font><font style="color: rgb(38, 38, 38);">revoking, </font><font style="color: rgb(19, 19, 19);">limiting </font><font style="color: rgb(38, 38, 38);">or curtailing or seeking to revoke, </font><font style="color: rgb(19, 19, 19);">limit </font><font style="color: rgb(38, 38, 38);">or curtail such power and authority </font><font style="color: rgb(19, 19, 19);">or </font><font style="color: rgb(38, 38, 38);">qualification.</font></div>
      <div style="text-align: justify;"><br>
      </div>
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      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(c)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(19, 19, 19);"><u>Authorization</u></font><font style="color: rgb(66, 66, 66);"><u>; </u></font><font style="color: rgb(38, 38, 38);"><u>Enforcement</u>. The Company </font><font style="color: rgb(19, 19, 19);">has </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">requisite </font><font style="color: rgb(38, 38, 38);">corporate power and authority to enter into and to consummate the transactions contemplated by this </font><font style="color: rgb(19, 19, 19);">Agreement </font><font style="color: rgb(38, 38, 38);">and each of </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">other Transaction Documents and otherwise to carry out </font><font style="color: rgb(19, 19, 19);">its </font><font style="color: rgb(38, 38, 38);">obligations </font><font style="color: rgb(19, 19, 19);">hereunder </font><font style="color: rgb(38, 38, 38);">and thereunder. </font><font style="color: rgb(19, 19, 19);">The </font><font style="color: rgb(38, 38, 38);">execution and </font><font style="color: rgb(19, 19, 19);">delivery </font><font style="color: rgb(38, 38, 38);">of </font><font style="color: rgb(19, 19, 19);">this Agreement </font><font style="color: rgb(38, 38, 38);">and </font><font style="color: rgb(19, 19, 19);">each </font><font style="color: rgb(38, 38, 38);">of the other </font><font style="color: rgb(19, 19, 19);">Transaction </font><font style="color: rgb(38, 38, 38);">Documents by the Company and the consummation by </font><font style="color: rgb(19, 19, 19);">it
        </font><font style="color: rgb(38, 38, 38);">of the transactions contemplated hereby and thereby </font><font style="color: rgb(19, 19, 19);">h</font><font style="color: rgb(66, 66, 66);">a</font><font style="color: rgb(38, 38, 38);">ve been duly
          authorized by all necessary action on the part of the Company and no further action </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">required by the Company, </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Board of </font><font style="color: rgb(19, 19, 19);">Directors </font><font style="color: rgb(38, 38, 38);">or the </font><font style="color: rgb(66, 66, 66);">Company's </font><font style="color: rgb(38, 38, 38);">stockholders </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">connection herewith or therewith </font><font style="color: rgb(19, 19, 19);">other than in </font><font style="color: rgb(38, 38, 38);">connection with </font><font style="color: rgb(19, 19, 19);">the Required Approvals. </font><font style="color: rgb(38, 38, 38);">This </font><font style="color: rgb(19, 19, 19);">Agreement </font><font style="color: rgb(38, 38, 38);">and each other </font><font style="color: rgb(19, 19, 19);">Transaction </font><font style="color: rgb(38, 38, 38);">Document </font><font style="color: rgb(19, 19, 19);">to </font><font style="color: rgb(38, 38, 38);">which </font><font style="color: rgb(19, 19, 19);">it </font><font style="color: rgb(38, 38, 38);">is a party has been (or upon delivery will</font><font style="font-weight: bold; color: rgb(38, 38, 38);">&#160;</font><font style="color: rgb(38, 38, 38);">have been) duly executed by </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Company and, when delivered </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">accordance with </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">terms hereof and thereof</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">will</font><font style="font-weight: bold; color: rgb(38, 38, 38);">&#160;</font><font style="color: rgb(38, 38, 38);">constitute the </font><font style="color: rgb(19, 19, 19);">valid </font><font style="color: rgb(38, 38, 38);">and binding obligation of the
          Company enforceable against the </font><font style="color: rgb(19, 19, 19);">Company </font><font style="color: rgb(38, 38, 38);">in accordance with </font><font style="color: rgb(19, 19, 19);">its </font><font style="color: rgb(38, 38, 38);">terms,





          except (i) as </font><font style="color: rgb(19, 19, 19);">limited </font><font style="color: rgb(38, 38, 38);">by general </font><font style="color: rgb(19, 19, 19);">equitable </font><font style="color: rgb(38, 38, 38);">principles and
          applicable bankruptcy, insolvency, reorganization</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">moratorium and other </font><font style="color: rgb(19, 19, 19);">laws </font><font style="color: rgb(38, 38, 38);">of general application affecting enforcement of creditors' rights generally, (ii) as limited by </font><font style="color: rgb(19, 19, 19);">laws </font><font style="color: rgb(38, 38, 38);">relating to </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">availability of specific performance</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(19, 19, 19);">injunctive </font><font style="color: rgb(38, 38, 38);">relief or other equitable remedies and (iii) </font><font style="color: rgb(19, 19, 19);">insofar </font><font style="color: rgb(38, 38, 38);">as </font><font style="color: rgb(19, 19, 19);">indemnification </font><font style="color: rgb(38, 38, 38);">and contribution provisions may be </font><font style="color: rgb(19, 19, 19);">limi</font><font style="color: rgb(82, 82, 82);">t</font><font style="color: rgb(38, 38, 38);">ed by applicable </font><font style="color: rgb(19, 19, 19);">law</font><font style="color: rgb(82, 82, 82);">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(d)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(19, 19, 19);"><u>No </u></font><font style="color: rgb(38, 38, 38);"><u>Conflicts</u></font><font style="color: rgb(82, 82, 82);">. </font><font style="color: rgb(38, 38, 38);">The execution</font><font style="color: rgb(100, 100, 100);">, </font><font style="color: rgb(38, 38, 38);">delivery and performance by </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Company of this Agreement and </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">other </font><font style="color: rgb(66, 66, 66);">Transaction
        </font><font style="color: rgb(19, 19, 19);">Documents </font><font style="color: rgb(38, 38, 38);">to which </font><font style="color: rgb(19, 19, 19);">it is </font><font style="color: rgb(38, 38, 38);">a party</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">issuance </font><font style="color: rgb(38, 38, 38);">and sale of the Securities and the consummation </font><font style="color: rgb(19, 19, 19);">by it </font><font style="color: rgb(38, 38, 38);">of the transactions contemplated hereby and thereby </font><font style="color: rgb(66, 66, 66);">do </font><font style="color: rgb(19, 19, 19);">not </font><font style="color: rgb(38, 38, 38);">and will</font><font style="font-weight: bold; color: rgb(38, 38, 38);">&#160;</font><font style="color: rgb(38, 38, 38);">not (i) conflict with or violate any provision of the </font><font style="color: rgb(66, 66, 66);">Company's or any </font><font style="color: rgb(38, 38, 38);">Sub</font><font style="color: rgb(66, 66, 66);">s</font><font style="color: rgb(38, 38, 38);">idi</font><font style="color: rgb(66, 66, 66);">a</font><font style="color: rgb(38, 38, 38);">ry</font><font style="color: rgb(100, 100, 100);">'</font><font style="color: rgb(66, 66, 66);">s </font><font style="color: rgb(38, 38, 38);">certificate or articles </font><font style="color: rgb(19, 19, 19);">of incorporation</font><font style="color: rgb(100, 100, 100);">, </font><font style="color: rgb(38, 38, 38);">bylaws or other organizational or charter documents, or </font><font style="color: rgb(19, 19, 19);">(ii) </font><font style="color: rgb(38, 38, 38);">conflict
          with, or constitute a default </font><font style="color: rgb(19, 19, 19);">(o</font><font style="color: rgb(66, 66, 66);">r </font><font style="color: rgb(38, 38, 38);">an event </font><font style="color: rgb(19, 19, 19);">that </font><font style="color: rgb(38, 38, 38);">with notice or </font><font style="color: rgb(19, 19, 19);">lapse </font><font style="color: rgb(38, 38, 38);">of time </font><font style="color: rgb(19, 19, 19);">or both </font><font style="color: rgb(38, 38, 38);">would become a default) under</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">result in the creation of any Lien </font><font style="color: rgb(19, 19, 19);">upon </font><font style="color: rgb(38, 38, 38);">any of the properties or assets of the Company or any Subsidiary, or give to others any rights of termination</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">amendment</font><font style="color: rgb(100, 100, 100);">, </font><font style="color: rgb(38, 38, 38);">anti-dilution or similar adjustments, acceleration or cancellation (with or without notice, lapse of time </font><font style="color: rgb(19, 19, 19);">or </font><font style="color: rgb(38, 38, 38);">both) of, any agreeme</font><font style="color: rgb(66, 66, 66);">n</font><font style="color: rgb(19, 19, 19);">t</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">credit </font><font style="color: rgb(19, 19, 19);">facility</font><font style="color: rgb(66, 66, 66);">, </font><font style="color: rgb(38, 38, 38);">debt </font><font style="color: rgb(19, 19, 19);">or other instrument (evidencing </font><font style="color: rgb(38, 38, 38);">a </font><font style="color: rgb(19, 19, 19);">Company or </font><font style="color: rgb(38, 38, 38);">Subsidiary debt </font><font style="color: rgb(19, 19, 19);">or </font><font style="color: rgb(38, 38, 38);">otherwise)
          to which the Company or any Subsidiary </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">a party or by which any property or asset of the Company or any Subsidiary </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">bound or affected</font><font style="color: rgb(100, 100, 100);">, </font><font style="color: rgb(38, 38, 38);">or (iii) subject to </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Required </font><font style="color: rgb(19, 19, 19);">Approvals</font><font style="color: rgb(66, 66, 66);">, </font><font style="color: rgb(38, 38, 38);">conflict with or result in a violation of any </font><font style="color: rgb(19, 19, 19);">law, </font><font style="color: rgb(38, 38, 38);">rule</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">regulation, order</font><font style="color: rgb(124, 124, 124);">,
        </font><font style="color: rgb(19, 19, 19);">j</font><font style="color: rgb(66, 66, 66);">u</font><font style="color: rgb(38, 38, 38);">dgment, injunction, decree or </font><font style="color: rgb(19, 19, 19);">other </font><font style="color: rgb(38, 38, 38);">restriction of any court or governmental authority to which the </font><font style="color: rgb(19, 19, 19);">Company or </font><font style="color: rgb(38, 38, 38);">a </font><font style="color: rgb(19, 19, 19);">Subsidiary is
        </font><font style="color: rgb(38, 38, 38);">subject </font><font style="color: rgb(19, 19, 19);">(including </font><font style="color: rgb(38, 38, 38);">federal and state securities laws and regulations), </font><font style="color: rgb(19, 19, 19);">o</font><font style="color: rgb(66, 66, 66);">r </font><font style="color: rgb(38, 38, 38);">by which </font><font style="color: rgb(66, 66, 66);">any </font><font style="color: rgb(38, 38, 38);">property or asset of the Company or a
          Subsidiary </font><font style="color: rgb(19, 19, 19);">i</font><font style="color: rgb(66, 66, 66);">s </font><font style="color: rgb(38, 38, 38);">bound or affected; except </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">the case of each of clauses (ii) and (iii), such as would not reasonably be expected to result in a Material Adverse Effect.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(e)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(38, 38, 38);"><u>Filings, Consents and Approvals</u>. The Company </font><font style="color: rgb(19, 19, 19);">is
        </font><font style="color: rgb(38, 38, 38);">not required to obtain any consent, waiver</font><font style="color: rgb(100, 100, 100);">, </font><font style="color: rgb(38, 38, 38);">authorization or order of, give any </font><font style="color: rgb(19, 19, 19);">notice </font><font style="color: rgb(38, 38, 38);">to, or make any filing or registration with</font><font style="color: rgb(100, 100, 100);">, </font><font style="color: rgb(38, 38, 38);">any court or other federal</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">state, </font><font style="color: rgb(19, 19, 19);">local </font><font style="color: rgb(38, 38, 38);">or other governmental authority or other Person </font><font style="color: rgb(19, 19, 19);">i</font><font style="color: rgb(66, 66, 66);">n </font><font style="color: rgb(38, 38, 38);">connection with </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">execution</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">delivery and performance by </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Company </font><font style="color: rgb(19, 19, 19);">of </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">Transaction </font><font style="color: rgb(38, 38, 38);">Documents, other than: (i) </font><font style="color: rgb(19, 19, 19);">the filings required pursuant to </font><font style="color: rgb(38, 38, 38);">Section 4.3 </font><font style="color: rgb(19, 19, 19);">of </font><font style="color: rgb(38, 38, 38);">this Agreement, (ii) the </font><font style="color: rgb(19, 19, 19);">filing </font><font style="color: rgb(38, 38, 38);">with the </font><font style="color: rgb(19, 19, 19);">Commission of </font><font style="color: rgb(38, 38, 38);">the Prospectus Supplement</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(38, 38, 38);">(iii) application(s) to each applicable Trading Market for the </font><font style="color: rgb(19, 19, 19);">listing </font><font style="color: rgb(38, 38, 38);">of the Shares and
          Pre-Funded Warrant Shares </font><font style="color: rgb(19, 19, 19);">for </font><font style="color: rgb(38, 38, 38);">trading thereon in the time and manner required thereby and (iv) </font><font style="color: rgb(36, 36, 36);">such </font><font style="color: rgb(15, 15, 15);">filings </font><font style="color: rgb(36, 36, 36);">as are </font><font style="color: rgb(15, 15, 15);">required </font><font style="color: rgb(56, 56, 56);">to </font><font style="color: rgb(36, 36, 36);">be
          made </font><font style="color: rgb(15, 15, 15);">under </font><font style="color: rgb(36, 36, 36);">applicable </font><font style="color: rgb(56, 56, 56);">state </font><font style="color: rgb(36, 36, 36);">securities </font><font style="color: rgb(15, 15, 15);">laws </font><font style="color: rgb(36, 36, 36);">and/or the </font><font style="color: rgb(56, 56, 56);">rules </font><font style="color: rgb(36, 36, 36);">of the </font><font style="color: rgb(15, 15, 15);">Financial





          Industry Regulatory </font><font style="color: rgb(36, 36, 36);">Authority, </font><font style="color: rgb(15, 15, 15);">Inc. </font><font style="color: rgb(36, 36, 36);">(collectively, the </font><font style="color: rgb(56, 56, 56);">&#8220;<u>Required





          </u></font><font style="color: rgb(36, 36, 36);"><u>Approvals</u></font><font style="color: rgb(79, 79, 79);">&#8221;</font><font style="color: rgb(36, 36, 36);">).</font></div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">(f)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(36, 36, 36);"><u>Issuance of the Securities; Registration</u>. The Securities are duly authorized and</font><font style="color: rgb(96, 96, 96);">, </font><font style="color: rgb(36, 36, 36);">when issued and paid for </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">accordance with </font><font style="color: rgb(15, 15, 15);">the </font><font style="color: rgb(36, 36, 36);">applicable Transaction Documents</font><font style="color: rgb(124, 124, 124);">, </font><font style="color: rgb(36, 36, 36);">will be duly and validly </font><font style="color: rgb(15, 15, 15);">issued, </font><font style="color: rgb(56, 56, 56);">fully </font><font style="color: rgb(36, 36, 36);">paid and nonassessable, free and clear of all </font><font style="color: rgb(15, 15, 15);">Liens imposed </font><font style="color: rgb(56, 56, 56);">by the </font><font style="color: rgb(15, 15, 15);">Company and free of all legends. The </font><font style="color: rgb(38, 38, 38);">Pre-Funded</font><font style="color: rgb(15, 15, 15);"> Warrant Shares, when
          issued in accordance with the terms of the </font><font style="color: rgb(38, 38, 38);">Pre-Funded</font><font style="color: rgb(15, 15, 15);"> Warrants, will be </font><font style="color: rgb(36, 36, 36);">duly and validly </font><font style="color: rgb(15, 15, 15);">issued, </font><font style="color: rgb(56, 56, 56);">fully </font><font style="color: rgb(36, 36, 36);">paid and nonassessable, free and clear of all </font><font style="color: rgb(15, 15, 15);">Liens imposed </font><font style="color: rgb(56, 56, 56);">by the </font><font style="color: rgb(15, 15, 15);">Company and free of all legends</font><font style="color: rgb(36, 36, 36);">. The Company has reserved </font><font style="color: rgb(15, 15, 15);">from its </font><font style="color: rgb(36, 36, 36);">duly authorized capital stock </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(36, 36, 36);">maximum number of shares of </font><font style="color: rgb(15, 15, 15);">Common </font><font style="color: rgb(36, 36, 36);">Stock </font><font style="color: rgb(15, 15, 15);">issuable </font><font style="color: rgb(36, 36, 36);">pursuant to this Agreement and the </font><font style="color: rgb(38, 38, 38);">Pre-Funded</font><font style="color: rgb(36, 36, 36);"> Warrants. </font><font style="color: rgb(15, 15, 15);">The </font><font style="color: rgb(36, 36, 36);">Company has </font><font style="color: rgb(15, 15, 15);">prepared </font><font style="color: rgb(56, 56, 56);">and </font><font style="color: rgb(15, 15, 15);">filed </font><font style="color: rgb(36, 36, 36);">the Registration Statement in conformity with the requirements of the Securities Act, </font><font style="color: rgb(15, 15, 15);">including





        </font><font style="color: rgb(56, 56, 56);">the Prospectus, </font><font style="color: rgb(36, 36, 36);">and such amendments and supplements thereto as </font><font style="color: rgb(56, 56, 56);">may </font><font style="color: rgb(15, 15, 15);">have </font><font style="color: rgb(36, 36, 36);">been required to the date of this Agreement. </font><font style="color: rgb(15, 15, 15);">The </font><font style="color: rgb(36, 36, 36);">Registration Statement </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(36, 36, 36);">effective under the Securities Act and no stop </font><font style="color: rgb(15, 15, 15);">order </font><font style="color: rgb(36, 36, 36);">preventing or
          suspending the effectiveness </font><font style="color: rgb(15, 15, 15);">of </font><font style="color: rgb(36, 36, 36);">the Registration Statement or suspending </font><font style="color: rgb(15, 15, 15);">or </font><font style="color: rgb(36, 36, 36);">preventing the use of the Prospectus </font><font style="color: rgb(15, 15, 15);">has </font><font style="color: rgb(36, 36, 36);">been issued by </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(36, 36, 36);">Commission and no proceedings </font><font style="color: rgb(15, 15, 15);">for </font><font style="color: rgb(56, 56, 56);">that </font><font style="color: rgb(36, 36, 36);">purpose have been </font><font style="color: rgb(15, 15, 15);">instituted </font><font style="color: rgb(56, 56, 56);">or, </font><font style="color: rgb(36, 36, 36);">to the knowledge of </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(36, 36, 36);">Company,





          are threatened </font><font style="color: rgb(56, 56, 56);">in </font><font style="color: rgb(36, 36, 36);">writing by the Commission</font><font style="color: rgb(79, 79, 79);">. </font><font style="color: rgb(36, 36, 36);">The Company, if
          required by the rules and regulations of </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(36, 36, 36);">Commission, shall file the Prospectus Supplement with the Commission pursuant to Rule </font><font style="color: rgb(56, 56, 56);">424(b). </font><font style="color: rgb(36, 36, 36);">At the time the Registration Statement and any post-effective amendments thereto </font><font style="color: rgb(15, 15, 15);">became </font><font style="color: rgb(36, 36, 36);">effective, at </font><font style="color: rgb(15, 15, 15);">the </font><font style="color: rgb(36, 36, 36);">date of this Agreement and at </font><font style="color: rgb(15, 15, 15);">the </font><font style="color: rgb(36, 36, 36);">Closing Date</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(36, 36, 36);">the Regis</font><font style="color: rgb(79, 79, 79);">tra</font><font style="color: rgb(36, 36, 36);">tion
          Statement and any amendments </font><font style="color: rgb(56, 56, 56);">thereto </font><font style="color: rgb(36, 36, 36);">conformed and will conform </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">a</font><font style="color: rgb(15, 15, 15);">ll </font><font style="color: rgb(36, 36, 36);">material respects to the requirements of the Securities </font><font style="color: rgb(15, 15, 15);">Act </font><font style="color: rgb(36, 36, 36);">and did not and will </font><font style="color: rgb(56, 56, 56);">not </font><font style="color: rgb(36, 36, 36);">contain any untrue statement of a material fact or omit to state any material fact </font><font style="color: rgb(56, 56, 56);">required to </font><font style="color: rgb(36, 36, 36);">be stated </font><font style="color: rgb(15, 15, 15);">therein </font><font style="color: rgb(36, 36, 36);">or necessary </font><font style="color: rgb(15, 15, 15);">to </font><font style="color: rgb(36, 36, 36);">make the statements </font><font style="color: rgb(56, 56, 56);">therein </font><font style="color: rgb(36, 36, 36);">not misleading; and the Prospectus Supplement and any amendments </font><font style="color: rgb(56, 56, 56);">or </font><font style="color: rgb(36, 36, 36);">supplements thereto</font><font style="color: rgb(96, 96, 96);">, </font><font style="color: rgb(36, 36, 36);">at the </font><font style="color: rgb(56, 56, 56);">time </font><font style="color: rgb(36, 36, 36);">the Prospectus Supplement or any </font><font style="color: rgb(56, 56, 56);">amendment </font><font style="color: rgb(36, 36, 36);">or </font><font style="color: rgb(56, 56, 56);">supplement </font><font style="color: rgb(15, 15, 15);">thereto </font><font style="color: rgb(36, 36, 36);">was </font><font style="color: rgb(15, 15, 15);">issued </font><font style="color: rgb(36, 36, 36);">and at the Closing Date, conformed and will </font><font style="color: rgb(56, 56, 56);">conform in </font><font style="color: rgb(36, 36, 36);">all material respects to the </font><font style="color: rgb(56, 56, 56);">requirements </font><font style="color: rgb(36, 36, 36);">of the Securities Act
          and did not and will </font><font style="color: rgb(15, 15, 15);">not </font><font style="color: rgb(36, 36, 36);">contain an untrue statement of a material fact or omit to state a material fact necessary </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">orde</font><font style="color: rgb(96, 96, 96);">r </font><font style="color: rgb(36, 36, 36);">to make the statements </font><font style="color: rgb(15, 15, 15);">therein</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(36, 36, 36);">in the </font><font style="color: rgb(15, 15, 15);">light </font><font style="color: rgb(36, 36, 36);">of </font><font style="color: rgb(15, 15, 15);">the </font><font style="color: rgb(36, 36, 36);">circumstances under which </font><font style="color: rgb(56, 56, 56);">they </font><font style="color: rgb(36, 36, 36);">were </font><font style="color: rgb(56, 56, 56);">made, </font><font style="color: rgb(36, 36, 36);">not misleading. The Company is eligible to use Form S-3 </font><font style="color: rgb(56, 56, 56);">under </font><font style="color: rgb(36, 36, 36);">the Securities Act and </font><font style="color: rgb(56, 56, 56);">it </font><font style="color: rgb(36, 36, 36);">meets </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(36, 36, 36);">transaction </font><font style="color: rgb(56, 56, 56);">requirements </font><font style="color: rgb(36, 36, 36);">as set forth </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">General Instruction I.B.1 of </font><font style="color: rgb(56, 56, 56);">Form </font><font style="color: rgb(15, 15, 15);">S-3.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">(g)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(36, 36, 36);"><u>Capitalization</u></font><font style="color: rgb(124, 124, 124);">. </font><font style="color: rgb(36, 36, 36);">The authorized capital stock of the Company consists of 125,000,000 shares of Common Stock and 10,000,000 shares of preferred stock, par value $0.0001 per share. The Company&#8217;s disclosure of its issued and outstanding capital
          stock in the SEC Reports containing such disclosure was accurate in all material respects as of the date indicated in such SEC Reports. All of the issued and outstanding shares of Common Stock have been duly authorized and validly issued and are
          fully paid and non-assessable. None of the outstanding shares of capital stock of the Company were issued in violation of any preemptive or other similar rights of any securityholder of the Company which have not been waived</font><font style="color: rgb(52, 52, 52);">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(h)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(35, 35, 35);"><u>SEC </u></font><font style="color: rgb(12, 12, 12);"><u>Reports; </u></font><font style="color: rgb(35, 35, 35);"><u>Financial Statements</u>. </font><font style="color: rgb(12, 12, 12);">The </font><font style="color: rgb(35, 35, 35);">Company has filed all reports</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">schedules</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">forms, statements </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(35, 35, 35);">other
          documents required to be filed by the Company under the Securities Act and </font><font style="color: rgb(52, 52, 52);">the Exchange </font><font style="color: rgb(35, 35, 35);">Act, including pursuant to Section </font><font style="color: rgb(52, 52, 52);">13(a) </font><font style="color: rgb(35, 35, 35);">or </font><font style="color: rgb(52, 52, 52);">15(d) </font><font style="color: rgb(35, 35, 35);">thereof</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">for the year preceding </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(35, 35, 35);">date hereof (or </font><font style="color: rgb(52, 52, 52);">such </font><font style="color: rgb(35, 35, 35);">shorter period as the Company was </font><font style="color: rgb(52, 52, 52);">required </font><font style="color: rgb(35, 35, 35);">by </font><font style="color: rgb(12, 12, 12);">law </font><font style="color: rgb(35, 35, 35);">or regulation </font><font style="color: rgb(52, 52, 52);">to </font><font style="color: rgb(35, 35, 35);">file such material) (the foregoing materials, </font><font style="color: rgb(12, 12, 12);">incl</font><font style="color: rgb(52, 52, 52);">ud</font><font style="color: rgb(80, 80, 80);">i</font><font style="color: rgb(35, 35, 35);">ng the exhibits thereto and documents incorporated by reference therein</font><font style="color: rgb(103, 103, 103);">, </font><font style="color: rgb(35, 35, 35);">together with the Prospectus and the Prospectus Supplement, </font><font style="color: rgb(52, 52, 52);">being </font><font style="color: rgb(35, 35, 35);">collectively </font><font style="color: rgb(52, 52, 52);">referred </font><font style="color: rgb(35, 35, 35);">to herein as the </font><font style="color: rgb(52, 52, 52);">&#8220;<u>SEC </u></font><font style="color: rgb(35, 35, 35);"><u>Reports</u>&#8221;) on a timely </font><font style="color: rgb(52, 52, 52);">basis </font><font style="color: rgb(35, 35, 35);">or has received a valid extension of </font><font style="color: rgb(52, 52, 52);">such </font><font style="color: rgb(35, 35, 35);">time of </font><font style="color: rgb(52, 52, 52);">filing </font><font style="color: rgb(35, 35, 35);">and </font><font style="color: rgb(52, 52, 52);">has </font><font style="color: rgb(35, 35, 35);">filed </font><font style="color: rgb(52, 52, 52);">any such </font><font style="color: rgb(35, 35, 35);">SEC Reports prior </font><font style="color: rgb(52, 52, 52);">to </font><font style="color: rgb(35, 35, 35);">the expiration of any such extension. As of their respective dates, the SEC Reports complied </font><font style="color: rgb(52, 52, 52);">in </font><font style="color: rgb(35, 35, 35);">al</font><font style="color: rgb(12, 12, 12);">l </font><font style="color: rgb(52, 52, 52);">material </font><font style="color: rgb(35, 35, 35);">respects with
          the requirements of the Securities Act and the Exchange Act, </font><font style="color: rgb(52, 52, 52);">as </font><font style="color: rgb(35, 35, 35);">applicable</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">and none of the SEC Reports, when filed, contained any untrue statement of a material fact or omitted </font><font style="color: rgb(12, 12, 12);">to </font><font style="color: rgb(35, 35, 35);">state a material </font><font style="color: rgb(12, 12, 12);">fact </font><font style="color: rgb(35, 35, 35);">required </font><font style="color: rgb(52, 52, 52);">to </font><font style="color: rgb(35, 35, 35);">be stated therein or </font><font style="color: rgb(12, 12, 12);">necessary in </font><font style="color: rgb(35, 35, 35);">order to make the statements therein</font><font style="color: rgb(103, 103, 103);">, </font><font style="color: rgb(52, 52, 52);">in the light </font><font style="color: rgb(35, 35, 35);">of the circumstances under which </font><font style="color: rgb(52, 52, 52);">they were </font><font style="color: rgb(35, 35, 35);">made, </font><font style="color: rgb(52, 52, 52);">not </font><font style="color: rgb(35, 35, 35);">misleading</font><font style="color: rgb(80, 80, 80);">. </font><font style="color: rgb(35, 35, 35);">The </font><font style="color: rgb(52, 52, 52);">financial </font><font style="color: rgb(35, 35, 35);">statements of </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(35, 35, 35);">Company </font><font style="color: rgb(12, 12, 12);">included in </font><font style="color: rgb(35, 35, 35);">the SEC Reports complied in all material respects
          with applicable accounting requirements and the rules and regulations of the Commission with respect </font><font style="color: rgb(52, 52, 52);">thereto </font><font style="color: rgb(35, 35, 35);">as </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(35, 35, 35);">effect at the time of </font><font style="color: rgb(12, 12, 12);">fili</font><font style="color: rgb(52, 52, 52);">ng</font><font style="color: rgb(80, 80, 80);">. </font><font style="color: rgb(35, 35, 35);">Such financial statements have </font><font style="color: rgb(52, 52, 52);">been </font><font style="color: rgb(35, 35, 35);">prepared </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(35, 35, 35);">accordance with United States generally accepted accounting </font><font style="color: rgb(52, 52, 52);">principles </font><font style="color: rgb(35, 35, 35);">applied </font><font style="color: rgb(52, 52, 52);">on a </font><font style="color: rgb(35, 35, 35);">consistent </font><font style="color: rgb(52, 52, 52);">basis </font><font style="color: rgb(35, 35, 35);">during the periods involved (</font><font style="color: rgb(80, 80, 80);">&#8220;</font><font style="color: rgb(35, 35, 35);"><u>GAAP</u></font><font style="color: rgb(80, 80, 80);">&#8221;</font><font style="color: rgb(35, 35, 35);">)</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">except as </font><font style="color: rgb(52, 52, 52);">may </font><font style="color: rgb(35, 35, 35);">be otherwise specified </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(35, 35, 35);">such </font><font style="color: rgb(52, 52, 52);">financial </font><font style="color: rgb(35, 35, 35);">statements or the notes </font><font style="color: rgb(52, 52, 52);">thereto </font><font style="color: rgb(35, 35, 35);">and except that unaudited financial </font><font style="color: rgb(52, 52, 52);">statements may not </font><font style="color: rgb(35, 35, 35);">contain all footnotes required by GAAP, </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(35, 35, 35);">fairly
          present </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(35, 35, 35);">all material </font><font style="color: rgb(52, 52, 52);">respects </font><font style="color: rgb(35, 35, 35);">the financial position of the
          Company and </font><font style="color: rgb(12, 12, 12);">its </font><font style="color: rgb(35, 35, 35);">consolidated Subsidiaries as </font><font style="color: rgb(12, 12, 12);">of </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(35, 35, 35);">for the dates thereof and the </font><font style="color: rgb(12, 12, 12);">results </font><font style="color: rgb(35, 35, 35);">of operations and cash flows for </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(35, 35, 35);">periods then ended</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(52, 52, 52);">subject, </font><font style="color: rgb(35, 35, 35);">in the </font><font style="color: rgb(52, 52, 52);">case </font><font style="color: rgb(35, 35, 35);">of unaudited statements, </font><font style="color: rgb(12, 12, 12);">to </font><font style="color: rgb(52, 52, 52);">norma</font><font style="color: rgb(12, 12, 12);">l</font><font style="color: rgb(103, 103, 103);">, </font><font style="color: rgb(12, 12, 12);">immaterial, </font><font style="color: rgb(35, 35, 35);">year-end audit adjustments.</font></div>
      <div><br>
      </div>
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          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(i)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(35, 35, 35);"><u>Material Changes; Undisclosed Events, </u></font><font style="color: rgb(52, 52, 52);"><u>Liabilities





          </u></font><font style="color: rgb(35, 35, 35);"><u>or Developments</u>. Since the date of the </font><font style="color: rgb(52, 52, 52);">most recent </font><font style="color: rgb(35, 35, 35);">unaudited financial </font><font style="color: rgb(52, 52, 52);">statements </font><font style="color: rgb(35, 35, 35);">included within the SEC Reports</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">except as disclosed in the SEC Reports, (i)
          there has been no event, occurrence or development that has had or that would reasonably be expected to result in a Material Adverse Effect</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(35, 35, 35);">(ii) the
          Company has </font><font style="color: rgb(52, 52, 52);">not </font><font style="color: rgb(14, 14, 14);">incurred </font><font style="color: rgb(35, 35, 35);">any material </font><font style="color: rgb(14, 14, 14);">liabilities </font><font style="color: rgb(35, 35, 35);">(contingent or otherwise) other </font><font style="color: rgb(52, 52, 52);">than </font><font style="color: rgb(35, 35, 35);">(A) trade </font><font style="color: rgb(14, 14, 14);">payables </font><font style="color: rgb(35, 35, 35);">and accrued expenses </font><font style="color: rgb(52, 52, 52);">incurred </font><font style="color: rgb(35, 35, 35);">in </font><font style="color: rgb(14, 14, 14);">the </font><font style="color: rgb(35, 35, 35);">ordinary course of business consistent with past practice and (B) </font><font style="color: rgb(14, 14, 14);">liabilities </font><font style="color: rgb(35, 35, 35);">not required to be reflected </font><font style="color: rgb(14, 14, 14);">in </font><font style="color: rgb(35, 35, 35);">the Company</font><font style="color: rgb(82, 82, 82);">'</font><font style="color: rgb(35, 35, 35);">s financial statements pursuant to GAAP </font><font style="color: rgb(14, 14, 14);">or
        </font><font style="color: rgb(35, 35, 35);">disclosed in filings made with the Commission, (iii) the Company has </font><font style="color: rgb(14, 14, 14);">not </font><font style="color: rgb(35, 35, 35);">altered its method of accounting, (iv)
          the Company </font><font style="color: rgb(52, 52, 52);">has </font><font style="color: rgb(35, 35, 35);">not declared or made any dividend or distribution of cash </font><font style="color: rgb(52, 52, 52);">or </font><font style="color: rgb(35, 35, 35);">other property </font><font style="color: rgb(52, 52, 52);">to </font><font style="color: rgb(14, 14, 14);">its </font><font style="color: rgb(35, 35, 35);">stockholders </font><font style="color: rgb(14, 14, 14);">or </font><font style="color: rgb(35, 35, 35);">purchased, redeemed or made any agreements to </font><font style="color: rgb(52, 52, 52);">purchase </font><font style="color: rgb(35, 35, 35);">or redeem any shares of</font><font style="font-weight: bold; color: rgb(35, 35, 35);">&#160;</font><font style="color: rgb(14, 14, 14);">its </font><font style="color: rgb(35, 35, 35);">capital stock </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(35, 35, 35);">(v) the Company
          has not issued any equity securities to </font><font style="color: rgb(52, 52, 52);">any </font><font style="color: rgb(35, 35, 35);">officer, di</font><font style="color: rgb(82, 82, 82);">r</font><font style="color: rgb(35, 35, 35);">ector or
          Affiliate</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(35, 35, 35);">except pursuant to existing Company equity plans or arrangements</font><font style="color: rgb(82, 82, 82);">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(j)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(35, 35, 35);">&#160;<u>Litigation</u></font><font style="color: rgb(82, 82, 82);">. </font><font style="color: rgb(35, 35, 35);">There </font><font style="color: rgb(14, 14, 14);">is no </font><font style="color: rgb(35, 35, 35);">Proceeding and, to the knowledge of the Company</font><font style="color: rgb(52, 52, 52);">, there is no threatened Proceeding </font><font style="color: rgb(35, 35, 35);">which (i) would reasonably be expected to adversely affect or challenge </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(14, 14, 14);">legality</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(35, 35, 35);">validity or enforceability of </font><font style="color: rgb(52, 52, 52);">any of </font><font style="color: rgb(35, 35, 35);">the Transaction Documents or the Securities or (ii) would, if
          there were an unfavorable </font><font style="color: rgb(52, 52, 52);">decision, </font><font style="color: rgb(35, 35, 35);">reasonably be expected to result </font><font style="color: rgb(52, 52, 52);">in </font><font style="color: rgb(35, 35, 35);">a Material </font><font style="color: rgb(14, 14, 14);">Adverse </font><font style="color: rgb(35, 35, 35);">Effect. Neither the Company nor any Subsidiary, nor any director or officer thereof (in his or her capacity as such), is or
          has been the subject of any Proceeding involving a claim of violation or liability under federal or state securities laws or a claim of breach of fiduciary duty. There has not been, and to </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(35, 35, 35);">knowledge of the Company</font><font style="color: rgb(82, 82, 82);">, there </font><font style="color: rgb(35, 35, 35);">is not </font><font style="color: rgb(52, 52, 52);">pending </font><font style="color: rgb(35, 35, 35);">or contemplated, </font><font style="color: rgb(52, 52, 52);">any </font><font style="color: rgb(14, 14, 14);">investigation </font><font style="color: rgb(35, 35, 35);">by the Commission involving the Company or any current
          or </font><font style="color: rgb(52, 52, 52);">former </font><font style="color: rgb(35, 35, 35);">director or officer of </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(35, 35, 35);">Company (in </font><font style="color: rgb(52, 52, 52);">his </font><font style="color: rgb(35, 35, 35);">or her capacity as such). The Commission has not issued any stop order or other order suspending </font><font style="color: rgb(14, 14, 14);">the </font><font style="color: rgb(52, 52, 52);">effectiveness </font><font style="color: rgb(35, 35, 35);">of any registration statement filed by the Company or any Subsidiary under the Exchange Act or the Securities Act.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(k)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(14, 14, 14);"><u>Labor </u></font><font style="color: rgb(35, 35, 35);"><u>Relations</u>. No </font><font style="color: rgb(52, 52, 52);">labor </font><font style="color: rgb(35, 35, 35);">dispute exists or, to the </font><font style="color: rgb(14, 14, 14);">knowledge </font><font style="color: rgb(35, 35, 35);">of the Company, </font><font style="color: rgb(52, 52, 52);">is imminent </font><font style="color: rgb(35, 35, 35);">with </font><font style="color: rgb(52, 52, 52);">respect </font><font style="color: rgb(35, 35, 35);">to </font><font style="color: rgb(52, 52, 52);">any





        </font><font style="color: rgb(35, 35, 35);">of </font><font style="color: rgb(14, 14, 14);">the </font><font style="color: rgb(35, 35, 35);">employees of </font><font style="color: rgb(14, 14, 14);">the </font><font style="color: rgb(35, 35, 35);">Company, which would reasonably be expected to </font><font style="color: rgb(14, 14, 14);">result </font><font style="color: rgb(35, 35, 35);">in a Material Adverse Effect. </font><font style="color: rgb(52, 52, 52);">None of the
          Company's or its </font><font style="color: rgb(35, 35, 35);">Subsidiaries</font><font style="color: rgb(82, 82, 82);">' </font><font style="color: rgb(52, 52, 52);">employees is </font><font style="color: rgb(82, 82, 82);">a </font><font style="color: rgb(52, 52, 52);">member of a union that relates to such </font><font style="color: rgb(35, 35, 35);">employee</font><font style="color: rgb(82, 82, 82);">'</font><font style="color: rgb(52, 52, 52);">s relationship with </font><font style="color: rgb(35, 35, 35);">the </font><font style="color: rgb(52, 52, 52);">Company </font><font style="color: rgb(35, 35, 35);">or </font><font style="color: rgb(52, 52, 52);">such </font><font style="color: rgb(35, 35, 35);">Subsidiary,





          and neither the Company nor any of </font><font style="color: rgb(14, 14, 14);">its </font><font style="color: rgb(35, 35, 35);">Subsidiaries </font><font style="color: rgb(14, 14, 14);">is </font><font style="color: rgb(35, 35, 35);">a party
          to a </font><font style="color: rgb(52, 52, 52);">collective </font><font style="color: rgb(35, 35, 35);">bargaining agreement</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(35, 35, 35);">and </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(35, 35, 35);">Company </font><font style="color: rgb(52, 52, 52);">and its </font><font style="color: rgb(35, 35, 35);">Subsidiaries believe that their </font><font style="color: rgb(52, 52, 52);">relationships </font><font style="color: rgb(35, 35, 35);">with their employees are good. To the knowledge of the Company, no executive officer of the Company or any </font><font style="color: rgb(52, 52, 52);">Subsidiary,





        </font><font style="color: rgb(14, 14, 14);">is</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(35, 35, 35);">or is now expected to be, </font><font style="color: rgb(14, 14, 14);">in </font><font style="color: rgb(35, 35, 35);">violation of any material term of any employment contract, confidentiality</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(35, 35, 35);">disclosure or proprietary information agreement or </font><font style="color: rgb(52, 52, 52);">non-competition </font><font style="color: rgb(35, 35, 35);">agreement, or any other contract or agreement or any </font><font style="color: rgb(14, 14, 14);">restrictive </font><font style="color: rgb(52, 52, 52);">covenant </font><font style="color: rgb(14, 14, 14);">in </font><font style="color: rgb(35, 35, 35);">favor of any third </font><font style="color: rgb(52, 52, 52);">party, </font><font style="color: rgb(35, 35, 35);">and the continued
          employment of each </font><font style="color: rgb(52, 52, 52);">such </font><font style="color: rgb(35, 35, 35);">executive officer does not subject the Company or any of its Subsidiaries to </font><font style="color: rgb(52, 52, 52);">any </font><font style="color: rgb(14, 14, 14);">liability </font><font style="color: rgb(35, 35, 35);">with respect </font><font style="color: rgb(14, 14, 14);">to </font><font style="color: rgb(52, 52, 52);">any </font><font style="color: rgb(35, 35, 35);">of





          the foregoing matters. The Company and its Subsidiaries are </font><font style="color: rgb(14, 14, 14);">in </font><font style="color: rgb(52, 52, 52);">compliance </font><font style="color: rgb(35, 35, 35);">with </font><font style="color: rgb(52, 52, 52);">all </font><font style="color: rgb(35, 35, 35);">U</font><font style="color: rgb(82, 82, 82);">.</font><font style="color: rgb(35, 35, 35);">S</font><font style="color: rgb(82, 82, 82);">. </font><font style="color: rgb(14, 14, 14);">federal, </font><font style="color: rgb(35, 35, 35);">state, local and </font><font style="color: rgb(52, 52, 52);">foreign laws </font><font style="color: rgb(35, 35, 35);">and regulations </font><font style="color: rgb(52, 52, 52);">relating </font><font style="color: rgb(35, 35, 35);">to employment </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(35, 35, 35);">employment practices, </font><font style="color: rgb(52, 52, 52);">terms </font><font style="color: rgb(35, 35, 35);">and </font><font style="color: rgb(52, 52, 52);">conditions </font><font style="color: rgb(35, 35, 35);">of employment </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(35, 35, 35);">wages and hours</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(35, 35, 35);">except where the failure to be in compliance would not</font><font style="color: rgb(82, 82, 82);">, </font><font style="color: rgb(14, 14, 14);">individually </font><font style="color: rgb(35, 35, 35);">or in the aggregate, </font><font style="color: rgb(52, 52, 52);">reasonably </font><font style="color: rgb(35, 35, 35);">be expected to </font><font style="color: rgb(14, 14, 14);">have </font><font style="color: rgb(35, 35, 35);">a </font><font style="color: rgb(14, 14, 14);">Material </font><font style="color: rgb(35, 35, 35);">Adverse Effect.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(I)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(35, 35, 35);"><u>Compliance</u>. Neither the Company nor any Subsidiary: (i) is in default </font><font style="color: rgb(52, 52, 52);">under </font><font style="color: rgb(35, 35, 35);">or in violation of (and no </font><font style="color: rgb(52, 52, 52);">event has </font><font style="color: rgb(35, 35, 35);">occurred that has not been waived
          that, with </font><font style="color: rgb(52, 52, 52);">notice </font><font style="color: rgb(35, 35, 35);">or </font><font style="color: rgb(14, 14, 14);">lapse </font><font style="color: rgb(35, 35, 35);">of time or both, would result in a
          default by the Company or any Subsidiary under), </font><font style="color: rgb(51, 51, 51);">nor </font><font style="color: rgb(35, 35, 35);">has the Company or </font><font style="color: rgb(51, 51, 51);">any </font><font style="color: rgb(35, 35, 35);">Subsidiary received written notice of a </font><font style="color: rgb(14, 14, 14);">claim </font><font style="color: rgb(35, 35, 35);">that </font><font style="color: rgb(14, 14, 14);">i</font><font style="color: rgb(66, 66, 66);">t </font><font style="color: rgb(14, 14, 14);">is in </font><font style="color: rgb(35, 35, 35);">default under or that </font><font style="color: rgb(51, 51, 51);">it is </font><font style="color: rgb(14, 14, 14);">in </font><font style="color: rgb(35, 35, 35);">violation of, any indenture, </font><font style="color: rgb(14, 14, 14);">loan </font><font style="color: rgb(35, 35, 35);">or credit agreement or any other agreement or </font><font style="color: rgb(14, 14, 14);">instrument </font><font style="color: rgb(35, 35, 35);">to which it </font><font style="color: rgb(14, 14, 14);">is </font><font style="color: rgb(35, 35, 35);">a party or by which </font><font style="color: rgb(14, 14, 14);">it </font><font style="color: rgb(35, 35, 35);">or any of </font><font style="color: rgb(14, 14, 14);">its </font><font style="color: rgb(35, 35, 35);">properties </font><font style="color: rgb(14, 14, 14);">is </font><font style="color: rgb(35, 35, 35);">bound





          (whether or </font><font style="color: rgb(14, 14, 14);">not </font><font style="color: rgb(35, 35, 35);">such default or violation has been waived), (ii) is in violation of any </font><font style="color: rgb(14, 14, 14);">judgment</font><font style="color: rgb(66, 66, 66);">, </font><font style="color: rgb(35, 35, 35);">decree or order of any court, arbitrator or other governmental authority or (iii) </font><font style="color: rgb(14, 14, 14);">is </font><font style="color: rgb(35, 35, 35);">or has </font><font style="color: rgb(66, 66, 66);">been </font><font style="color: rgb(14, 14, 14);">i</font><font style="color: rgb(66, 66, 66);">n </font><font style="color: rgb(35, 35, 35);">violation of any </font><font style="color: rgb(51, 51, 51);">statute, </font><font style="color: rgb(66, 66, 66);">rule, </font><font style="color: rgb(35, 35, 35);">ordinance or </font><font style="color: rgb(14, 14, 14);">regulation </font><font style="color: rgb(35, 35, 35);">of any governmental authority, including without limitation all foreign, federal, state and </font><font style="color: rgb(14, 14, 14);">local laws </font><font style="color: rgb(35, 35, 35);">relating to taxes, environmental
          protection, occupational health and safety</font><font style="color: rgb(96, 96, 96);">, </font><font style="color: rgb(35, 35, 35);">product quality and safety and employment and labor matters, except in </font><font style="color: rgb(51, 51, 51);">each </font><font style="color: rgb(35, 35, 35);">case as would not </font><font style="color: rgb(14, 14, 14);">reasonably </font><font style="color: rgb(35, 35, 35);">be expected </font><font style="color: rgb(66, 66, 66);">to </font><font style="color: rgb(35, 35, 35);">result </font><font style="color: rgb(51, 51, 51);">in </font><font style="color: rgb(35, 35, 35);">a Material Adverse Effect.</font></div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(m)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(35, 35, 35);"><u>Environmental Laws</u>. The Company and its Subsidiaries (i) are in compliance with all federal,
          state, local and </font><font style="color: rgb(14, 14, 14);">foreign </font><font style="color: rgb(35, 35, 35);">laws </font><font style="color: rgb(51, 51, 51);">relating </font><font style="color: rgb(35, 35, 35);">to pollution or
          protection of human health or the </font><font style="color: rgb(51, 51, 51);">environment </font><font style="color: rgb(35, 35, 35);">(including </font><font style="color: rgb(51, 51, 51);">ambient </font><font style="color: rgb(35, 35, 35);">air, surface water, groundwater</font><font style="color: rgb(130, 130, 130);">, </font><font style="color: rgb(14, 14, 14);">land </font><font style="color: rgb(35, 35, 35);">surface or </font><font style="color: rgb(51, 51, 51);">subsurface





          strata), </font><font style="color: rgb(14, 14, 14);">including </font><font style="color: rgb(35, 35, 35);">laws </font><font style="color: rgb(14, 14, 14);">relat</font><font style="color: rgb(66, 66, 66);">i</font><font style="color: rgb(35, 35, 35);">ng to emissions, discharges, releases or threatened releases of chemicals, pollutants, contaminants, </font><font style="color: rgb(14, 14, 14);">or </font><font style="color: rgb(35, 35, 35);">toxic or hazardous </font><font style="color: rgb(51, 51, 51);">substances </font><font style="color: rgb(35, 35, 35);">or wastes (coll</font><font style="color: rgb(96, 96, 96);">e</font><font style="color: rgb(66, 66, 66);">ctively</font><font style="color: rgb(96, 96, 96);">,
        </font><font style="color: rgb(66, 66, 66);">&#8220;<u>Hazardous </u></font><font style="color: rgb(35, 35, 35);"><u>Materials</u>&#8221;) </font><font style="color: rgb(66, 66, 66);">into the environment, </font><font style="color: rgb(51, 51, 51);">or
          otherwise relating </font><font style="color: rgb(35, 35, 35);">to </font><font style="color: rgb(66, 66, 66);">the </font><font style="color: rgb(51, 51, 51);">manufacture, processing, </font><font style="color: rgb(35, 35, 35);">distribution,





          use, treatment, storage, disposal</font><font style="color: rgb(96, 96, 96);">, </font><font style="color: rgb(35, 35, 35);">transport or </font><font style="color: rgb(51, 51, 51);">handling </font><font style="color: rgb(35, 35, 35);">of
          Hazardous Materials, as well as all </font><font style="color: rgb(51, 51, 51);">authorizations, </font><font style="color: rgb(35, 35, 35);">codes, decrees, demands, or demand </font><font style="color: rgb(14, 14, 14);">letters, </font><font style="color: rgb(51, 51, 51);">injunctions, </font><font style="color: rgb(35, 35, 35);">judgments, </font><font style="color: rgb(14, 14, 14);">l</font><font style="color: rgb(35, 35, 35);">icenses, notices or notice </font><font style="color: rgb(14, 14, 14);">letters, </font><font style="color: rgb(35, 35, 35);">orders, permits, plans or regulations, </font><font style="color: rgb(14, 14, 14);">issued</font><font style="color: rgb(66, 66, 66);">, </font><font style="color: rgb(35, 35, 35);">entered, promulgated </font><font style="color: rgb(51, 51, 51);">or </font><font style="color: rgb(66, 66, 66);">approve</font><font style="color: rgb(51, 51, 51);">d </font><font style="color: rgb(66, 66, 66);">thereunder </font><font style="color: rgb(51, 51, 51);">(&#8220;<u>Environmental </u></font><font style="color: rgb(35, 35, 35);"><u>Laws</u>&#8221;); (ii) have received </font><font style="color: rgb(66, 66, 66);">all </font><font style="color: rgb(51, 51, 51);">permits </font><font style="color: rgb(14, 14, 14);">licenses </font><font style="color: rgb(35, 35, 35);">or other </font><font style="color: rgb(51, 51, 51);">approvals </font><font style="color: rgb(35, 35, 35);">required
          of them </font><font style="color: rgb(14, 14, 14);">under </font><font style="color: rgb(35, 35, 35);">applicable Environmental Laws to conduct </font><font style="color: rgb(51, 51, 51);">their </font><font style="color: rgb(35, 35, 35);">respective





          businesses; and (iii) are </font><font style="color: rgb(51, 51, 51);">in </font><font style="color: rgb(35, 35, 35);">compliance with </font><font style="color: rgb(51, 51, 51);">all terms and </font><font style="color: rgb(35, 35, 35);">conditions





          of </font><font style="color: rgb(51, 51, 51);">any </font><font style="color: rgb(35, 35, 35);">such permit, </font><font style="color: rgb(14, 14, 14);">lice</font><font style="color: rgb(66, 66, 66);">ns</font><font style="color: rgb(35, 35, 35);">e or approval where in each clause (i), (ii) and (iii), the failure to so comply would be reasonably expected to have, </font><font style="color: rgb(14, 14, 14);">individually </font><font style="color: rgb(35, 35, 35);">or </font><font style="color: rgb(51, 51, 51);">in </font><font style="color: rgb(35, 35, 35);">the aggregate, a Material Adverse Effect.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(n)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(35, 35, 35);"><u>Regulatory Permits</u>. The Company and </font><font style="color: rgb(51, 51, 51);">the </font><font style="color: rgb(35, 35, 35);">Subsidiaries possess all certificates, authorizations and permits </font><font style="color: rgb(51, 51, 51);">issued </font><font style="color: rgb(35, 35, 35);">by the </font><font style="color: rgb(51, 51, 51);">appropriate </font><font style="color: rgb(35, 35, 35);">federal, </font><font style="color: rgb(51, 51, 51);">state, </font><font style="color: rgb(35, 35, 35);">local or foreign regulatory authorities necessary to conduct their
          respective businesses </font><font style="color: rgb(51, 51, 51);">as </font><font style="color: rgb(35, 35, 35);">described </font><font style="color: rgb(14, 14, 14);">in </font><font style="color: rgb(35, 35, 35);">the SEC Reports, except
          where the </font><font style="color: rgb(14, 14, 14);">failure </font><font style="color: rgb(35, 35, 35);">to possess such permits would not reasonably be expected to result </font><font style="color: rgb(14, 14, 14);">in </font><font style="color: rgb(35, 35, 35);">a Material Adverse Effect (&#8220;<u>Material </u></font><font style="color: rgb(14, 14, 14);"><u>Permits</u></font><font style="color: rgb(66, 66, 66);">&#8221;</font><font style="color: rgb(35, 35, 35);">)</font><font style="color: rgb(66, 66, 66);">, </font><font style="color: rgb(35, 35, 35);">and neither the Company nor any Subsidiary has received any notice of proceedings relating to the </font><font style="color: rgb(51, 51, 51);">revocation </font><font style="color: rgb(35, 35, 35);">or modification of any Material Permit.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(o)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(14, 14, 14);"><u>Title </u></font><font style="color: rgb(35, 35, 35);"><u>to Assets</u>. The Company and the
          Subsidiaries have good and marketable </font><font style="color: rgb(51, 51, 51);">title </font><font style="color: rgb(14, 14, 14);">i</font><font style="color: rgb(66, 66, 66);">n </font><font style="color: rgb(35, 35, 35);">all real and
          personal property owned by them that </font><font style="color: rgb(51, 51, 51);">is material </font><font style="color: rgb(35, 35, 35);">to the </font><font style="color: rgb(51, 51, 51);">business </font><font style="color: rgb(35, 35, 35);">of </font><font style="color: rgb(51, 51, 51);">the </font><font style="color: rgb(35, 35, 35);">Company and the Subsidiaries, </font><font style="color: rgb(14, 14, 14);">in </font><font style="color: rgb(35, 35, 35);">each case </font><font style="color: rgb(51, 51, 51);">free </font><font style="color: rgb(35, 35, 35);">and clear of all Liens, except for (i) Liens as do not materially </font><font style="color: rgb(51, 51, 51);">affect </font><font style="color: rgb(35, 35, 35);">the value of such property and do not materially interfere with the use made </font><font style="color: rgb(51, 51, 51);">and </font><font style="color: rgb(66, 66, 66);">proposed </font><font style="color: rgb(35, 35, 35);">to </font><font style="color: rgb(51, 51, 51);">be </font><font style="color: rgb(35, 35, 35);">made of such property by the Company and the Subsidiaries, (ii) Liens for </font><font style="color: rgb(51, 51, 51);">the </font><font style="color: rgb(35, 35, 35);">payment of </font><font style="color: rgb(14, 14, 14);">fed</font><font style="color: rgb(51, 51, 51);">eral</font><font style="color: rgb(96, 96, 96);">, </font><font style="color: rgb(51, 51, 51);">state </font><font style="color: rgb(35, 35, 35);">or other taxes, </font><font style="color: rgb(14, 14, 14);">for </font><font style="color: rgb(35, 35, 35);">which </font><font style="color: rgb(51, 51, 51);">appropriate </font><font style="color: rgb(35, 35, 35);">reserves





          have been made therefor </font><font style="color: rgb(14, 14, 14);">in </font><font style="color: rgb(35, 35, 35);">accordance with GAAP and, the payment of which </font><font style="color: rgb(14, 14, 14);">is </font><font style="color: rgb(35, 35, 35);">neither delinquent </font><font style="color: rgb(51, 51, 51);">nor subject </font><font style="color: rgb(35, 35, 35);">to penalties and (iii) Liens that would not, </font><font style="color: rgb(14, 14, 14);">individually </font><font style="color: rgb(35, 35, 35);">or in the aggregate, reasonably be expected </font><font style="color: rgb(66, 66, 66);">to </font><font style="color: rgb(35, 35, 35);">have a Material Adverse Event. Any real property and </font><font style="color: rgb(51, 51, 51);">facilities held </font><font style="color: rgb(66, 66, 66);">under </font><font style="color: rgb(14, 14, 14);">lease </font><font style="color: rgb(35, 35, 35);">by the Company </font><font style="color: rgb(51, 51, 51);">and </font><font style="color: rgb(35, 35, 35);">the Subsidiaries are held by them under valid, subsisting and </font><font style="color: rgb(51, 51, 51);">enforceable </font><font style="color: rgb(35, 35, 35);">leases with
          which the Company and the Subsidiaries </font><font style="color: rgb(51, 51, 51);">are in </font><font style="color: rgb(35, 35, 35);">compliance in all material respects.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(33, 33, 33);">(p)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(33, 33, 33);"><u>Intellectual Property</u></font><font style="color: rgb(98, 98, 98);">. </font><font style="color: rgb(51, 51, 51);">The </font><font style="color: rgb(33, 33, 33);">Company </font><font style="color: rgb(51, 51, 51);">and the </font><font style="color: rgb(33, 33, 33);">Subsidiaries have, or have rights to use, </font><font style="color: rgb(51, 51, 51);">all </font><font style="color: rgb(33, 33, 33);">patents, patent applications, trademarks, trademark applications, service marks, trade names, trade secrets</font><font style="color: rgb(98, 98, 98);">, </font><font style="color: rgb(51, 51, 51);">inventions, </font><font style="color: rgb(33, 33, 33);">copyrights, </font><font style="color: rgb(12, 12, 12);">licenses </font><font style="color: rgb(33, 33, 33);">and other </font><font style="color: rgb(12, 12, 12);">intellectual </font><font style="color: rgb(33, 33, 33);">property rights and similar </font><font style="color: rgb(51, 51, 51);">rights </font><font style="color: rgb(33, 33, 33);">necessary or required </font><font style="color: rgb(12, 12, 12);">for </font><font style="color: rgb(51, 51, 51);">use </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(33, 33, 33);">connection with </font><font style="color: rgb(51, 51, 51);">their





        </font><font style="color: rgb(12, 12, 12);">respective </font><font style="color: rgb(33, 33, 33);">businesses </font><font style="color: rgb(51, 51, 51);">as </font><font style="color: rgb(33, 33, 33);">described </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(51, 51, 51);">the </font><font style="color: rgb(33, 33, 33);">SEC Reports and where the failure </font><font style="color: rgb(51, 51, 51);">to </font><font style="color: rgb(33, 33, 33);">so





          have would have a Material Adverse Effect (collectively, </font><font style="color: rgb(51, 51, 51);">the </font><font style="color: rgb(98, 98, 98);">&#8220;</font><font style="color: rgb(12, 12, 12);"><u>I</u></font><font style="color: rgb(73, 73, 73);"><u>n</u></font><font style="color: rgb(33, 33, 33);"><u>tellectual Property R</u></font><font style="color: rgb(73, 73, 73);"><u>i</u></font><font style="color: rgb(33, 33, 33);"><u>ghts</u></font><font style="color: rgb(98, 98, 98);">&#8221;</font><font style="color: rgb(33, 33, 33);">)</font><font style="color: rgb(73, 73, 73);">. </font><font style="color: rgb(33, 33, 33);">Neither the Company nor any Subsidiary </font><font style="color: rgb(51, 51, 51);">has </font><font style="color: rgb(33, 33, 33);">received a written notice that any </font><font style="color: rgb(12, 12, 12);">of</font><font style="font-weight: bold; color: rgb(12, 12, 12);">&#160;</font><font style="color: rgb(33, 33, 33);">the material </font><font style="color: rgb(12, 12, 12);">Intellectual </font><font style="color: rgb(33, 33, 33);">Property Rights has expired</font><font style="color: rgb(98, 98, 98);">, </font><font style="color: rgb(33, 33, 33);">terminated or been abandoned, or is
          expected to expire or terminate or be abandoned, within two (2) years from the date of this Agreement, other than in accordance with </font><font style="color: rgb(51, 51, 51);">the </font><font style="color: rgb(33, 33, 33);">terms </font><font style="color: rgb(51, 51, 51);">of </font><font style="color: rgb(33, 33, 33);">the </font><font style="color: rgb(12, 12, 12);">Intellectual </font><font style="color: rgb(33, 33, 33);">Property Rights. Neither the Company nor any Subsidiary
        </font><font style="color: rgb(12, 12, 12);">has </font><font style="color: rgb(33, 33, 33);">received, since the date of the most </font><font style="color: rgb(51, 51, 51);">recent </font><font style="color: rgb(33, 33, 33);">unaudited </font><font style="color: rgb(51, 51, 51);">financial statements included </font><font style="color: rgb(33, 33, 33);">within the SEC Reports, a written notice </font><font style="color: rgb(51, 51, 51);">of </font><font style="color: rgb(33, 33, 33);">a
          claim or otherwise </font><font style="color: rgb(12, 12, 12);">has </font><font style="color: rgb(33, 33, 33);">any knowledge that the </font><font style="color: rgb(51, 51, 51);">Intellectual </font><font style="color: rgb(33, 33, 33);">Property





        </font><font style="color: rgb(12, 12, 12);">Rights </font><font style="color: rgb(33, 33, 33);">violate or infringe upon the rights of any </font><font style="color: rgb(12, 12, 12);">Person, </font><font style="color: rgb(33, 33, 33);">except
          as would not reasonably be </font><font style="color: rgb(51, 51, 51);">expected </font><font style="color: rgb(33, 33, 33);">to have a Material Adverse Effect. To </font><font style="color: rgb(51, 51, 51);">the </font><font style="color: rgb(33, 33, 33);">knowledge of </font><font style="color: rgb(51, 51, 51);">the </font><font style="color: rgb(33, 33, 33);">Company, all such Intellectual Property Rights </font><font style="color: rgb(51, 51, 51);">are </font><font style="color: rgb(33, 33, 33);">enforceable and there is </font><font style="color: rgb(51, 51, 51);">no </font><font style="color: rgb(33, 33, 33);">existing infringement by another Person of any of the </font><font style="color: rgb(51, 51, 51);">Intellectual Property </font><font style="color: rgb(33, 33, 33);">Rights. The Company </font><font style="color: rgb(51, 51, 51);">and </font><font style="color: rgb(12, 12, 12);">its </font><font style="color: rgb(33, 33, 33);">Subsidiaries





          have taken reasonable </font><font style="color: rgb(51, 51, 51);">security measures </font><font style="color: rgb(33, 33, 33);">to protect the secrecy, confidentiality and value of all of their intellectual properties</font><font style="color: rgb(98, 98, 98);">, </font><font style="color: rgb(33, 33, 33);">except where failure </font><font style="color: rgb(73, 73, 73);">t</font><font style="color: rgb(12, 12, 12);">o </font><font style="color: rgb(33, 33, 33);">do so
          would not, </font><font style="color: rgb(12, 12, 12);">individually </font><font style="color: rgb(33, 33, 33);">or </font><font style="color: rgb(51, 51, 51);">in </font><font style="color: rgb(33, 33, 33);">the aggregate, reasonably </font><font style="color: rgb(51, 51, 51);">be </font><font style="color: rgb(33, 33, 33);">expected to have a Material Adverse </font><font style="color: rgb(51, 51, 51);">Effect.</font></div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(33, 33, 33);">(q)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(33, 33, 33);"><u>Insurance</u>. The Company and the Subsidiaries are </font><font style="color: rgb(51, 51, 51);">insured





        </font><font style="color: rgb(33, 33, 33);">by </font><font style="color: rgb(12, 12, 12);">insurers </font><font style="color: rgb(33, 33, 33);">of recognized </font><font style="color: rgb(51, 51, 51);">financial </font><font style="color: rgb(33, 33, 33);">responsibility against such </font><font style="color: rgb(12, 12, 12);">losses </font><font style="color: rgb(33, 33, 33);">and risks </font><font style="color: rgb(51, 51, 51);">and </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(51, 51, 51);">such </font><font style="color: rgb(33, 33, 33);">amounts as are </font><font style="color: rgb(51, 51, 51);">prudent and customary </font><font style="color: rgb(33, 33, 33);">in the
          businesses in which the Company and the Subsidiaries are engaged</font><font style="color: rgb(98, 98, 98);">. </font><font style="color: rgb(33, 33, 33);">Neither the Company nor </font><font style="color: rgb(51, 51, 51);">any </font><font style="color: rgb(33, 33, 33);">Subsidiary </font><font style="color: rgb(51, 51, 51);">has any </font><font style="color: rgb(33, 33, 33);">reason to believe that </font><font style="color: rgb(51, 51, 51);">it </font><font style="color: rgb(33, 33, 33);">will not be able to renew </font><font style="color: rgb(12, 12, 12);">its </font><font style="color: rgb(51, 51, 51);">existing </font><font style="color: rgb(12, 12, 12);">insurance </font><font style="color: rgb(33, 33, 33);">coverage as and when such coverage expires or </font><font style="color: rgb(12, 12, 12);">to </font><font style="color: rgb(33, 33, 33);">obtain </font><font style="color: rgb(51, 51, 51);">similar </font><font style="color: rgb(33, 33, 33);">coverage from similar </font><font style="color: rgb(12, 12, 12);">insurers </font><font style="color: rgb(33, 33, 33);">as </font><font style="color: rgb(51, 51, 51);">may </font><font style="color: rgb(33, 33, 33);">be </font><font style="color: rgb(51, 51, 51);">necessary to </font><font style="color: rgb(33, 33, 33);">continue its business.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(33, 33, 33);">(r)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(33, 33, 33);"><u>Related Person Transactions</u>. There are </font><font style="color: rgb(51, 51, 51);">no
          business relationships </font><font style="color: rgb(33, 33, 33);">or </font><font style="color: rgb(73, 73, 73);">related </font><font style="color: rgb(33, 33, 33);">person </font><font style="color: rgb(51, 51, 51);">transactions, </font><font style="color: rgb(33, 33, 33);">as defined </font><font style="color: rgb(51, 51, 51);">in </font><font style="color: rgb(12, 12, 12);">Item </font><font style="color: rgb(33, 33, 33);">404 of Regulation S-K </font><font style="color: rgb(51, 51, 51);">under </font><font style="color: rgb(33, 33, 33);">the Exchange Act, involving the Company or any Subsidiary or any other person required to be described in the Prospectus which </font><font style="color: rgb(51, 51, 51);">have </font><font style="color: rgb(33, 33, 33);">not been described </font><font style="color: rgb(51, 51, 51);">as required.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(s)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(15, 15, 15);"><u>Certain Fees</u>. </font><font style="color: rgb(35, 35, 35);">Except as set </font><font style="color: rgb(15, 15, 15);">forth in </font><font style="color: rgb(35, 35, 35);">the Prospectus Supplement</font><font style="color: rgb(56, 56, 56);">, </font><font style="color: rgb(35, 35, 35);">no brokerage or </font><font style="color: rgb(15, 15, 15);">finder</font><font style="color: rgb(73, 73, 73);">'</font><font style="color: rgb(35, 35, 35);">s </font><font style="color: rgb(15, 15, 15);">fees </font><font style="color: rgb(35, 35, 35);">or commissions are
          or will be payable by the Company or any Subsidiary to any broker, financial advisor or consultant</font><font style="color: rgb(93, 93, 93);">, </font><font style="color: rgb(35, 35, 35);">finder, placement agent, </font><font style="color: rgb(15, 15, 15);">investment </font><font style="color: rgb(35, 35, 35);">banker, bank or other Person with </font><font style="color: rgb(73, 73, 73);">respect </font><font style="color: rgb(15, 15, 15);">to </font><font style="color: rgb(35, 35, 35);">the transactions contemplated by </font><font style="color: rgb(15, 15, 15);">the Transaction </font><font style="color: rgb(35, 35, 35);">Documents. </font><font style="color: rgb(15, 15, 15);">The </font><font style="color: rgb(35, 35, 35);">Purchasers shal</font><font style="color: rgb(15, 15, 15);">l </font><font style="color: rgb(35, 35, 35);">have </font><font style="color: rgb(15, 15, 15);">no </font><font style="color: rgb(35, 35, 35);">obligation






          with </font><font style="color: rgb(15, 15, 15);">respect </font><font style="color: rgb(35, 35, 35);">to any </font><font style="color: rgb(15, 15, 15);">fees </font><font style="color: rgb(35, 35, 35);">or with respect to any </font><font style="color: rgb(56, 56, 56);">claims </font><font style="color: rgb(35, 35, 35);">made by or on behalf of other Persons </font><font style="color: rgb(15, 15, 15);">for fees </font><font style="color: rgb(35, 35, 35);">of a type contemplated
        </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(35, 35, 35);">this Section that may be due </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(35, 35, 35);">connection with the
          transactions contemplated by the Transaction Documents.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(t)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(35, 35, 35);"><u>Investment Company</u>. </font><font style="color: rgb(56, 56, 56);">The </font><font style="color: rgb(35, 35, 35);">Company </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(56, 56, 56);">not, </font><font style="color: rgb(35, 35, 35);">and </font><font style="color: rgb(15, 15, 15);">immediately





        </font><font style="color: rgb(35, 35, 35);">after receipt of payment </font><font style="color: rgb(15, 15, 15);">for </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(35, 35, 35);">Securities will not be, an </font><font style="color: rgb(73, 73, 73);">&#8220;investment </font><font style="color: rgb(56, 56, 56);">company&#8221; </font><font style="color: rgb(35, 35, 35);">within the meaning of the Investment Company </font><font style="color: rgb(15, 15, 15);">Act </font><font style="color: rgb(35, 35, 35);">of 1940, as amended.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(u)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(35, 35, 35);"><u>Listing and Maintenance Requirements</u>. </font><font style="color: rgb(15, 15, 15);">The </font><font style="color: rgb(35, 35, 35);">Common Stock is registered pursuant to Section </font><font style="color: rgb(56, 56, 56);">12(b) or </font><font style="color: rgb(35, 35, 35);">12(g) of </font><font style="color: rgb(15, 15, 15);">the </font><font style="color: rgb(35, 35, 35);">Exchange Act, and the Company has </font><font style="color: rgb(56, 56, 56);">taken </font><font style="color: rgb(35, 35, 35);">no action designed to, or which </font><font style="color: rgb(56, 56, 56);">to </font><font style="color: rgb(35, 35, 35);">its knowledge </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(35, 35, 35);">likely to have the effect of, terminating the registration of </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(35, 35, 35);">Common Stock </font><font style="color: rgb(15, 15, 15);">under </font><font style="color: rgb(35, 35, 35);">the Exchange Act nor has the Company received any </font><font style="color: rgb(56, 56, 56);">notification </font><font style="color: rgb(35, 35, 35);">that the Commission </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(35, 35, 35);">contemplating terminating such registration. Except as
          set </font><font style="color: rgb(15, 15, 15);">forth </font><font style="color: rgb(35, 35, 35);">in </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(35, 35, 35);">SEC Reports, the Company has not, </font><font style="color: rgb(56, 56, 56);">in </font><font style="color: rgb(35, 35, 35);">the 12 months preceding the date </font><font style="color: rgb(15, 15, 15);">hereof, </font><font style="color: rgb(35, 35, 35);">received notice from any Trading
          Market on which </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(35, 35, 35);">Common Stock </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(35, 35, 35);">or has been listed or
          quoted </font><font style="color: rgb(56, 56, 56);">to </font><font style="color: rgb(35, 35, 35);">the </font><font style="color: rgb(56, 56, 56);">effect </font><font style="color: rgb(35, 35, 35);">that the Company </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(56, 56, 56);">not in compliance </font><font style="color: rgb(35, 35, 35);">with the listing or maintenance requirements of such Trading Market. The Common Stock </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(35, 35, 35);">currently eligible for electronic transfer </font><font style="color: rgb(56, 56, 56);">through </font><font style="color: rgb(35, 35, 35);">the Depository </font><font style="color: rgb(15, 15, 15);">Trust </font><font style="color: rgb(35, 35, 35);">Company or another established </font><font style="color: rgb(56, 56, 56);">clearing </font><font style="color: rgb(35, 35, 35);">corporation and the Company </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(35, 35, 35);">current in payment of the </font><font style="color: rgb(15, 15, 15);">fees </font><font style="color: rgb(35, 35, 35);">to </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(35, 35, 35);">Depository Trust </font><font style="color: rgb(15, 15, 15);">Company </font><font style="color: rgb(35, 35, 35);">(or such other established clearing corporation) </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(35, 35, 35);">connection with such electronic transfer.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(v)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(35, 35, 35);"><u>No </u></font><font style="color: rgb(15, 15, 15);"><u>Integrated </u></font><font style="color: rgb(35, 35, 35);"><u>Offering</u></font><font style="color: rgb(80, 80, 80);">. </font><font style="color: rgb(35, 35, 35);">Assuming the accuracy of the Purchasers</font><font style="color: rgb(80, 80, 80);">' </font><font style="color: rgb(15, 15, 15);">representations </font><font style="color: rgb(35, 35, 35);">and warranties set </font><font style="color: rgb(15, 15, 15);">forth in </font><font style="color: rgb(35, 35, 35);">Section 3</font><font style="color: rgb(80, 80, 80);">.</font><font style="color: rgb(35, 35, 35);">2, </font><font style="color: rgb(15, 15, 15);">neither </font><font style="color: rgb(35, 35, 35);">the Company</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">nor any of </font><font style="color: rgb(15, 15, 15);">its </font><font style="color: rgb(35, 35, 35);">Affiliates, nor any </font><font style="color: rgb(54, 54, 54);">Person </font><font style="color: rgb(35, 35, 35);">acting





          on its or their behalf has, directly or </font><font style="color: rgb(15, 15, 15);">ind</font><font style="color: rgb(54, 54, 54);">irect</font><font style="color: rgb(15, 15, 15);">ly</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">made any offers or sales of</font><font style="font-weight: bold; color: rgb(35, 35, 35);">&#160;</font><font style="color: rgb(35, 35, 35);">any security </font><font style="color: rgb(15, 15, 15);">or </font><font style="color: rgb(35, 35, 35);">solicited any offers to </font><font style="color: rgb(15, 15, 15);">buy </font><font style="color: rgb(35, 35, 35);">any security, under circumstances </font><font style="color: rgb(15, 15, 15);">that </font><font style="color: rgb(35, 35, 35);">would cause this offering of </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">Securities to be </font><font style="color: rgb(15, 15, 15);">integrated </font><font style="color: rgb(35, 35, 35);">with prior offerings by the Company </font><font style="color: rgb(15, 15, 15);">for </font><font style="color: rgb(35, 35, 35);">purposes of any applicable shareholder approval provisions of any Trading Market
          on which any of the securities of the Company are </font><font style="color: rgb(15, 15, 15);">listed </font><font style="color: rgb(35, 35, 35);">or designated</font><font style="color: rgb(80, 80, 80);">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(w)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(15, 15, 15);"><u>Tax </u></font><font style="color: rgb(35, 35, 35);"><u>Status</u>. Except for matters that would
          not</font><font style="color: rgb(98, 98, 98);">, </font><font style="color: rgb(15, 15, 15);">individually </font><font style="color: rgb(35, 35, 35);">or </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(35, 35, 35);">the aggregate, reasonably be expected </font><font style="color: rgb(54, 54, 54);">to </font><font style="color: rgb(35, 35, 35);">result in a Material Adverse Effect, the Company and </font><font style="color: rgb(54, 54, 54);">its </font><font style="color: rgb(35, 35, 35);">Subsidiaries each (i) has made or filed all United States federal</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">state and </font><font style="color: rgb(15, 15, 15);">local





          income </font><font style="color: rgb(35, 35, 35);">and all foreign </font><font style="color: rgb(15, 15, 15);">income </font><font style="color: rgb(35, 35, 35);">and </font><font style="color: rgb(54, 54, 54);">franchise </font><font style="color: rgb(15, 15, 15);">tax </font><font style="color: rgb(35, 35, 35);">returns, reports and declarations </font><font style="color: rgb(54, 54, 54);">required </font><font style="color: rgb(35, 35, 35);">by any </font><font style="color: rgb(15, 15, 15);">jurisdiction </font><font style="color: rgb(35, 35, 35);">to which it </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(35, 35, 35);">subject, (ii) has paid all </font><font style="color: rgb(15, 15, 15);">taxes </font><font style="color: rgb(35, 35, 35);">and other governmental assessments and charges that are material </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(35, 35, 35);">amount</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">shown or </font><font style="color: rgb(15, 15, 15);">determined </font><font style="color: rgb(35, 35, 35);">to be due on such </font><font style="color: rgb(15, 15, 15);">retu</font><font style="color: rgb(54, 54, 54);">rns</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">reports and declarations</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">except </font><font style="color: rgb(15, 15, 15);">for </font><font style="color: rgb(35, 35, 35);">such taxes, </font><font style="color: rgb(15, 15, 15);">if </font><font style="color: rgb(35, 35, 35);">any</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">as are being </font><font style="color: rgb(54, 54, 54);">contested </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(35, 35, 35);">good





          faith and as to which adequate </font><font style="color: rgb(54, 54, 54);">reserves </font><font style="color: rgb(35, 35, 35);">have been established by </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">Company and </font><font style="color: rgb(54, 54, 54);">(iii) </font><font style="color: rgb(35, 35, 35);">has </font><font style="color: rgb(54, 54, 54);">set </font><font style="color: rgb(35, 35, 35);">aside on </font><font style="color: rgb(15, 15, 15);">its </font><font style="color: rgb(35, 35, 35);">books provision reasonably adequate for </font><font style="color: rgb(15, 15, 15);">the </font><font style="color: rgb(35, 35, 35);">payment of all material
          taxes fo</font><font style="color: rgb(80, 80, 80);">r </font><font style="color: rgb(35, 35, 35);">periods subsequent to the periods to which such returns, reports or declarations apply. There </font><font style="color: rgb(54, 54, 54);">are </font><font style="color: rgb(15, 15, 15);">no </font><font style="color: rgb(35, 35, 35);">unpaid taxes </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(35, 35, 35);">any material amount claimed to be due by the </font><font style="color: rgb(15, 15, 15);">taxing </font><font style="color: rgb(35, 35, 35);">authority </font><font style="color: rgb(15, 15, 15);">of </font><font style="color: rgb(35, 35, 35);">any </font><font style="color: rgb(15, 15, 15);">jurisdiction,





        </font><font style="color: rgb(35, 35, 35);">and the officers </font><font style="color: rgb(15, 15, 15);">of </font><font style="color: rgb(35, 35, 35);">the Company or of any Subsidiary know of no basis for any </font><font style="color: rgb(54, 54, 54);">such </font><font style="color: rgb(35, 35, 35);">claim.</font></div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(x)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(15, 15, 15);"><u>Foreign </u></font><font style="color: rgb(35, 35, 35);"><u>Corrupt Practices</u>. Neither the </font><font style="color: rgb(15, 15, 15);">Company </font><font style="color: rgb(35, 35, 35);">nor </font><font style="color: rgb(54, 54, 54);">any </font><font style="color: rgb(35, 35, 35);">Subsidiary</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">nor </font><font style="color: rgb(15, 15, 15);">to </font><font style="color: rgb(35, 35, 35);">the knowledge of the Company or any Subsidiary</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">any agent or other person acting on behalf of the Company </font><font style="color: rgb(15, 15, 15);">or </font><font style="color: rgb(35, 35, 35);">any Subsidiary, has (i) directly or </font><font style="color: rgb(15, 15, 15);">indirectly</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(15, 15, 15);">used </font><font style="color: rgb(54, 54, 54);">any </font><font style="color: rgb(15, 15, 15);">funds </font><font style="color: rgb(35, 35, 35);">for </font><font style="color: rgb(54, 54, 54);">unlawful </font><font style="color: rgb(35, 35, 35);">contributions, gifts</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">entertainment or other </font><font style="color: rgb(15, 15, 15);">unlawful </font><font style="color: rgb(35, 35, 35);">expenses related to foreign or domestic political activity</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(35, 35, 35);">(ii) made any unlawful </font><font style="color: rgb(15, 15, 15);">payment </font><font style="color: rgb(35, 35, 35);">to foreign or domestic government officials or employees or to any foreign or domestic
          political parties or campaigns </font><font style="color: rgb(15, 15, 15);">from </font><font style="color: rgb(35, 35, 35);">corporate </font><font style="color: rgb(15, 15, 15);">funds, </font><font style="color: rgb(35, 35, 35);">(iii)</font><font style="font-weight: bold; color: rgb(35, 35, 35);">&#160;</font><font style="color: rgb(35, 35, 35);">failed to disclose fully </font><font style="color: rgb(54, 54, 54);">any </font><font style="color: rgb(35, 35, 35);">contribution </font><font style="color: rgb(15, 15, 15);">made by </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">Company or </font><font style="color: rgb(54, 54, 54);">any </font><font style="color: rgb(35, 35, 35);">Subsidiary





          (or made by any person acting on its behalf of which </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">Company </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(35, 35, 35);">aware) which is </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(35, 35, 35);">violation of </font><font style="color: rgb(15, 15, 15);">law, </font><font style="color: rgb(35, 35, 35);">or (iv) violated in
        </font><font style="color: rgb(54, 54, 54);">any </font><font style="color: rgb(35, 35, 35);">material respect any provision of FCPA.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(y)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(35, 35, 35);"><u>FDA</u>. As to each product subject </font><font style="color: rgb(54, 54, 54);">to </font><font style="color: rgb(35, 35, 35);">the </font><font style="color: rgb(12, 12, 12);">jurisdic</font><font style="color: rgb(54, 54, 54);">t</font><font style="color: rgb(12, 12, 12);">ion </font><font style="color: rgb(35, 35, 35);">of </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">U.S. Food and Drug Administration (&#8220;<u>FDA</u>&#8221;) under the Federal Food, Drug and Cosmetic Act, </font><font style="color: rgb(54, 54, 54);">as amended, </font><font style="color: rgb(35, 35, 35);">and </font><font style="color: rgb(54, 54, 54);">the regulat</font><font style="color: rgb(12, 12, 12);">ion</font><font style="color: rgb(54, 54, 54);">s </font><font style="color: rgb(35, 35, 35);">thereunder
          (&#8220;<u>FDCA</u></font><font style="color: rgb(77, 77, 77);">&#8221;</font><font style="color: rgb(35, 35, 35);">) that </font><font style="color: rgb(54, 54, 54);">is </font><font style="color: rgb(35, 35, 35);">manufactured, packaged</font><font style="color: rgb(77, 77, 77);">, </font><font style="color: rgb(35, 35, 35);">labeled</font><font style="color: rgb(98, 98, 98);">, </font><font style="color: rgb(35, 35, 35);">tested, distributed, </font><font style="color: rgb(54, 54, 54);">sold,





          and/or </font><font style="color: rgb(35, 35, 35);">marketed by the Company or </font><font style="color: rgb(54, 54, 54);">any </font><font style="color: rgb(35, 35, 35);">of </font><font style="color: rgb(54, 54, 54);">its </font><font style="color: rgb(35, 35, 35);">Subsidiaries (each such product, a </font><font style="color: rgb(98, 98, 98);">&#8220;</font><font style="color: rgb(35, 35, 35);"><u>Pharmaceutical Product</u></font><font style="color: rgb(98, 98, 98);">&#8221;</font><font style="color: rgb(35, 35, 35);">), </font><font style="color: rgb(54, 54, 54);">such </font><font style="color: rgb(35, 35, 35);">Pharmaceutical Product </font><font style="color: rgb(12, 12, 12);">is </font><font style="color: rgb(35, 35, 35);">being </font><font style="color: rgb(54, 54, 54);">manufac</font><font style="color: rgb(12, 12, 12);">tur</font><font style="color: rgb(54, 54, 54);">ed, </font><font style="color: rgb(35, 35, 35);">packaged,</font>&#160;<font style="color: rgb(12, 12, 12);">labeled, </font><font style="color: rgb(54, 54, 54);">tested, </font><font style="color: rgb(35, 35, 35);">distributed</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">sold and/or
          marketed by the Company </font><font style="color: rgb(54, 54, 54);">in </font><font style="color: rgb(35, 35, 35);">compliance with all applicable requirements </font><font style="color: rgb(54, 54, 54);">unde</font><font style="color: rgb(12, 12, 12);">r FDCA </font><font style="color: rgb(35, 35, 35);">and similar laws, rules and regulations relating to </font><font style="color: rgb(12, 12, 12);">registration</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(12, 12, 12);">investig</font><font style="color: rgb(54, 54, 54);">ationa</font><font style="color: rgb(12, 12, 12);">l </font><font style="color: rgb(35, 35, 35);">use, premarket </font><font style="color: rgb(12, 12, 12);">clearance</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(12, 12, 12);">licensure</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">or application approval, good manufacturing practices</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">good </font><font style="color: rgb(12, 12, 12);">labo</font><font style="color: rgb(54, 54, 54);">ratory </font><font style="color: rgb(35, 35, 35);">practices</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">good clinical practices</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">product </font><font style="color: rgb(12, 12, 12);">listing</font><font style="color: rgb(54, 54, 54);">, </font><font style="color: rgb(35, 35, 35);">quotas</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(12, 12, 12);">labeling, </font><font style="color: rgb(35, 35, 35);">advertising</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">record keeping and </font><font style="color: rgb(54, 54, 54);">fi</font><font style="color: rgb(12, 12, 12);">ling </font><font style="color: rgb(35, 35, 35);">of reports</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">except where the failure to be </font><font style="color: rgb(54, 54, 54);">i</font><font style="color: rgb(12, 12, 12);">n </font><font style="color: rgb(35, 35, 35);">compliance would not have a Material Adverse Effect. There </font><font style="color: rgb(12, 12, 12);">is </font><font style="color: rgb(54, 54, 54);">no pendi</font><font style="color: rgb(12, 12, 12);">ng</font><font style="color: rgb(54, 54, 54);">, </font><font style="color: rgb(35, 35, 35);">completed or, to the Company's </font><font style="color: rgb(54, 54, 54);">k</font><font style="color: rgb(12, 12, 12);">n</font><font style="color: rgb(54, 54, 54);">owledge, </font><font style="color: rgb(35, 35, 35);">threatened </font><font style="color: rgb(12, 12, 12);">i</font><font style="color: rgb(54, 54, 54);">n </font><font style="color: rgb(35, 35, 35);">writing, Proceeding</font><font style="color: rgb(54, 54, 54);">&#160;</font><font style="color: rgb(35, 35, 35);">against the Company or any of </font><font style="color: rgb(12, 12, 12);">its </font><font style="color: rgb(35, 35, 35);">Subsidiaries</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">and none of the Company or any of its Subsidiaries has received any notice, warning </font><font style="color: rgb(12, 12, 12);">le</font><font style="color: rgb(54, 54, 54);">tter </font><font style="color: rgb(35, 35, 35);">or other </font><font style="color: rgb(54, 54, 54);">communicatio</font><font style="color: rgb(12, 12, 12);">n </font><font style="color: rgb(35, 35, 35);">from





        </font><font style="color: rgb(12, 12, 12);">the </font><font style="color: rgb(54, 54, 54);">FDA </font><font style="color: rgb(35, 35, 35);">or any other governmen</font><font style="color: rgb(84, 84, 84);">t</font><font style="color: rgb(35, 35, 35);">al entity</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">which (i) contests the premarket clearance, </font><font style="color: rgb(12, 12, 12);">licensu</font><font style="color: rgb(54, 54, 54);">re, </font><font style="color: rgb(35, 35, 35);">registration, or approval of, the </font><font style="color: rgb(12, 12, 12);">uses </font><font style="color: rgb(35, 35, 35);">of, the distribution of, </font><font style="color: rgb(12, 12, 12);">the </font><font style="color: rgb(35, 35, 35);">manufacturing </font><font style="color: rgb(12, 12, 12);">or </font><font style="color: rgb(35, 35, 35);">packaging of, </font><font style="color: rgb(12, 12, 12);">the </font><font style="color: rgb(54, 54, 54);">testing </font><font style="color: rgb(35, 35, 35);">of, the sale of, or the </font><font style="color: rgb(12, 12, 12);">labeling </font><font style="color: rgb(35, 35, 35);">and promotion of any Pharmaceutical
          Product</font><font style="color: rgb(105, 105, 105);">, </font><font style="color: rgb(35, 35, 35);">(ii) withdraws </font><font style="color: rgb(54, 54, 54);">its </font><font style="color: rgb(35, 35, 35);">approval of, requests the
          recall, suspension</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">or seizure of, or withdraws or orders </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">withdrawal





          of advertising or </font><font style="color: rgb(54, 54, 54);">sales promotional mater</font><font style="color: rgb(12, 12, 12);">i</font><font style="color: rgb(54, 54, 54);">a</font><font style="color: rgb(12, 12, 12);">l</font><font style="color: rgb(54, 54, 54);">s </font><font style="color: rgb(35, 35, 35);">relating to, any Pharmaceutical Product, </font><font style="color: rgb(54, 54, 54);">(i</font><font style="color: rgb(12, 12, 12);">ii) </font><font style="color: rgb(35, 35, 35);">imposes a clinical hold on any clinical </font><font style="color: rgb(12, 12, 12);">investigation </font><font style="color: rgb(35, 35, 35);">by the Company or any of its Subsidiaries</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">(iv) enjoins production at any </font><font style="color: rgb(54, 54, 54);">fac</font><font style="color: rgb(12, 12, 12);">ility </font><font style="color: rgb(35, 35, 35);">of the Company
          or any </font><font style="color: rgb(12, 12, 12);">of </font><font style="color: rgb(35, 35, 35);">its Subsidiaries, </font><font style="color: rgb(12, 12, 12);">(v) </font><font style="color: rgb(35, 35, 35);">enters or proposes to enter </font><font style="color: rgb(12, 12, 12);">into </font><font style="color: rgb(35, 35, 35);">a consent decree of permanent injunction with the Company or any of </font><font style="color: rgb(12, 12, 12);">i</font><font style="color: rgb(54, 54, 54);">ts
        </font><font style="color: rgb(35, 35, 35);">Subsidiaries, or (vi) otherwise alleges any violation of any </font><font style="color: rgb(12, 12, 12);">l</font><font style="color: rgb(54, 54, 54);">aws, </font><font style="color: rgb(35, 35, 35);">rules





        </font><font style="color: rgb(54, 54, 54);">or regu</font><font style="color: rgb(12, 12, 12);">lation</font><font style="color: rgb(54, 54, 54);">s </font><font style="color: rgb(35, 35, 35);">by the Company or </font><font style="color: rgb(54, 54, 54);">any </font><font style="color: rgb(35, 35, 35);">of </font><font style="color: rgb(12, 12, 12);">its </font><font style="color: rgb(35, 35, 35);">Subsidiaries, and which</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">either </font><font style="color: rgb(12, 12, 12);">individ</font><font style="color: rgb(54, 54, 54);">ual</font><font style="color: rgb(12, 12, 12);">ly </font><font style="color: rgb(35, 35, 35);">or </font><font style="color: rgb(12, 12, 12);">i</font><font style="color: rgb(54, 54, 54);">n </font><font style="color: rgb(35, 35, 35);">the aggregate, would </font><font style="color: rgb(12, 12, 12);">have </font><font style="color: rgb(35, 35, 35);">a
          Material Adverse </font><font style="color: rgb(54, 54, 54);">Effect. </font><font style="color: rgb(35, 35, 35);">The properties, business and operations of the Company </font><font style="color: rgb(54, 54, 54);">have </font><font style="color: rgb(35, 35, 35);">been and are being conducted </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(35, 35, 35);">all material </font><font style="color: rgb(12, 12, 12);">respects </font><font style="color: rgb(35, 35, 35);">in accordance with all applicable </font><font style="color: rgb(12, 12, 12);">law</font><font style="color: rgb(54, 54, 54);">s</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">rules and </font><font style="color: rgb(12, 12, 12);">regulations </font><font style="color: rgb(35, 35, 35);">of the FDA. The Company has not been informed by the </font><font style="color: rgb(54, 54, 54);">FDA that </font><font style="color: rgb(35, 35, 35);">the FDA will prohibit the marketing, sale, </font><font style="color: rgb(54, 54, 54);">l</font><font style="color: rgb(12, 12, 12);">icens</font><font style="color: rgb(54, 54, 54);">e </font><font style="color: rgb(35, 35, 35);">or </font><font style="color: rgb(54, 54, 54);">use in </font><font style="color: rgb(35, 35, 35);">the United States of any product proposed to be </font><font style="color: rgb(54, 54, 54);">deve</font><font style="color: rgb(12, 12, 12);">loped</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">produced </font><font style="color: rgb(54, 54, 54);">or </font><font style="color: rgb(35, 35, 35);">marketed by </font><font style="color: rgb(12, 12, 12);">the </font><font style="color: rgb(35, 35, 35);">Company</font><font style="color: rgb(12, 12, 12);">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(z)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(35, 35, 35);"><u>Office of Foreign Assets Control</u>. Neither </font><font style="color: rgb(12, 12, 12);">t</font><font style="color: rgb(84, 84, 84);">h</font><font style="color: rgb(35, 35, 35);">e Company nor any Subsidiary nor</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(54, 54, 54);">to </font><font style="color: rgb(35, 35, 35);">the Company's knowledge, any director, officer, agent, employee or affiliate of </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">Company or any Subsidiary is currently </font><font style="color: rgb(54, 54, 54);">sub</font><font style="color: rgb(12, 12, 12);">ject </font><font style="color: rgb(35, 35, 35);">to any U.S. sanctions administered by </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">Office of </font><font style="color: rgb(12, 12, 12);">Foreign </font><font style="color: rgb(54, 54, 54);">Assets Contro</font><font style="color: rgb(12, 12, 12);">l </font><font style="color: rgb(54, 54, 54);">of </font><font style="color: rgb(35, 35, 35);">the </font><font style="color: rgb(54, 54, 54);">U.S. </font><font style="color: rgb(35, 35, 35);">Treasury Department </font><font style="color: rgb(54, 54, 54);">(&#8220;<u>OFAC</u>&#8221;).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">(aa)</font>&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(35, 35, 35);"><u>Money </u></font><font style="color: rgb(12, 12, 12);"><u>Lau</u></font><font style="color: rgb(54, 54, 54);"><u>ndering</u>. </font><font style="color: rgb(35, 35, 35);">The </font><font style="color: rgb(54, 54, 54);">operat</font><font style="color: rgb(12, 12, 12);">ions </font><font style="color: rgb(35, 35, 35);">of </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">Company and </font><font style="color: rgb(54, 54, 54);">its </font><font style="color: rgb(35, 35, 35);">Subsidiaries are and </font><font style="color: rgb(54, 54, 54);">have </font><font style="color: rgb(35, 35, 35);">been conducted at all times </font><font style="color: rgb(54, 54, 54);">in </font><font style="color: rgb(35, 35, 35);">compliance with </font><font style="color: rgb(54, 54, 54);">app</font><font style="color: rgb(12, 12, 12);">licable </font><font style="color: rgb(35, 35, 35);">financial record</font><font style="color: rgb(130, 130, 130);">-</font><font style="color: rgb(35, 35, 35);">keeping and </font><font style="color: rgb(12, 12, 12);">r</font><font style="color: rgb(54, 54, 54);">e</font><font style="color: rgb(12, 12, 12);">porting </font><font style="color: rgb(35, 35, 35);">requirements </font><font style="color: rgb(12, 12, 12);">of </font><font style="color: rgb(35, 35, 35);">the Currency and Foreign Transactions </font><font style="color: rgb(12, 12, 12);">R</font><font style="color: rgb(54, 54, 54);">eporti</font><font style="color: rgb(12, 12, 12);">ng </font><font style="color: rgb(35, 35, 35);">Act of </font><font style="color: rgb(54, 54, 54);">1970, </font><font style="color: rgb(35, 35, 35);">as amended, applicable money laundering statutes and applicable rules and regulations thereunder (collectively</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(105, 105, 105);">&#8220;</font><font style="color: rgb(35, 35, 35);"><u>Money </u></font><font style="color: rgb(12, 12, 12);"><u>Launderi</u></font><font style="color: rgb(54, 54, 54);"><u>ng </u></font><font style="color: rgb(12, 12, 12);"><u>Laws</u></font><font style="color: rgb(84, 84, 84);">&#8221;</font><font style="color: rgb(54, 54, 54);">)</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(54, 54, 54);">and </font><font style="color: rgb(35, 35, 35);">no Proceeding by or before any court or governmental agency, authority or body or any arbitrator </font><font style="color: rgb(12, 12, 12);">involving </font><font style="color: rgb(35, 35, 35);">the </font><font style="color: rgb(12, 12, 12);">Compa</font><font style="color: rgb(54, 54, 54);">ny </font><font style="color: rgb(35, 35, 35);">or any Subsidiary with respect to </font><font style="color: rgb(54, 54, 54);">the </font><font style="color: rgb(35, 35, 35);">Money </font><font style="color: rgb(12, 12, 12);">Laun</font><font style="color: rgb(54, 54, 54);">der</font><font style="color: rgb(12, 12, 12);">in</font><font style="color: rgb(54, 54, 54);">g </font><font style="color: rgb(35, 35, 35);">Laws </font><font style="color: rgb(12, 12, 12);">is </font><font style="color: rgb(35, 35, 35);">pending or</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(35, 35, 35);">to the knowledge of the Company or any Subsidiary, </font><font style="color: rgb(54, 54, 54);">threatened i</font><font style="color: rgb(12, 12, 12);">n </font><font style="color: rgb(35, 35, 35);">writing.</font></div>
      <div><br>
        <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
          <div class="BRPFPageBreak" style="page-break-after: always;">
            <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
        </div>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">3.2</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(35, 35, 35);"><u>Representations and Warranties of the </u></font><font style="color: rgb(54, 54, 54);"><u>Purchasers</u>.
        </font><font style="color: rgb(35, 35, 35);">Each Purchaser, for itself and </font><font style="color: rgb(54, 54, 54);">for</font><font style="font-weight: bold; color: rgb(54, 54, 54);">&#160;</font><font style="color: rgb(12, 12, 12);">no </font><font style="color: rgb(35, 35, 35);">other Purchaser, hereby </font><font style="color: rgb(54, 54, 54);">represents </font><font style="color: rgb(35, 35, 35);">and warrants as of </font><font style="color: rgb(12, 12, 12);">the </font><font style="color: rgb(35, 35, 35);">date hereof and as of the Closing Date to the Company as follows (unless </font><font style="color: rgb(54, 54, 54);">as </font><font style="color: rgb(35, 35, 35);">of a specific date therein, </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(35, 35, 35);">which case they </font><font style="color: rgb(54, 54, 54);">shall </font><font style="color: rgb(35, 35, 35);">be accurate as of such date):</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(a)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(38, 38, 38);"><u>Organization; </u></font><font style="color: rgb(19, 19, 19);"><u>Authority</u></font><font style="color: rgb(98, 98, 98);">. </font><font style="color: rgb(38, 38, 38);">Such Purchaser </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">either an individual or an entity duly </font><font style="color: rgb(19, 19, 19);">incorporated or </font><font style="color: rgb(38, 38, 38);">formed</font><font style="color: rgb(128, 128, 128);">, </font><font style="color: rgb(38, 38, 38);">validly </font><font style="color: rgb(19, 19, 19);">existing </font><font style="color: rgb(38, 38, 38);">and </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">good standing under the laws </font><font style="color: rgb(19, 19, 19);">of the
          jurisdiction of its incorporation or </font><font style="color: rgb(38, 38, 38);">formation with full </font><font style="color: rgb(19, 19, 19);">right</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(38, 38, 38);">corporate,





          partnership</font><font style="color: rgb(98, 98, 98);">, </font><font style="color: rgb(38, 38, 38);">limited </font><font style="color: rgb(19, 19, 19);">liability </font><font style="color: rgb(38, 38, 38);">company or similar power and
          authority </font><font style="color: rgb(19, 19, 19);">to </font><font style="color: rgb(38, 38, 38);">enter into and to </font><font style="color: rgb(19, 19, 19);">consummate </font><font style="color: rgb(38, 38, 38);">the transactions
          contemplated by the </font><font style="color: rgb(19, 19, 19);">Transaction Documents </font><font style="color: rgb(38, 38, 38);">and otherwise to carry out </font><font style="color: rgb(19, 19, 19);">its </font><font style="color: rgb(38, 38, 38);">obligations hereunder and thereunder. The </font><font style="color: rgb(19, 19, 19);">execution </font><font style="color: rgb(38, 38, 38);">and delivery of </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Transaction </font><font style="color: rgb(19, 19, 19);">Documents </font><font style="color: rgb(38, 38, 38);">and performance by such Purchaser of the transactions contemplated by the Transaction </font><font style="color: rgb(19, 19, 19);">Documents </font><font style="color: rgb(38, 38, 38);">have been </font><font style="color: rgb(19, 19, 19);">duly </font><font style="color: rgb(38, 38, 38);">authorized by all necessary corporate, </font><font style="color: rgb(19, 19, 19);">partnership, limited liability </font><font style="color: rgb(38, 38, 38);">company or similar action, as applicable</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(38, 38, 38);">on
          the part of such </font><font style="color: rgb(19, 19, 19);">Purchaser. </font><font style="color: rgb(38, 38, 38);">Each Transaction Document to which </font><font style="color: rgb(19, 19, 19);">it is </font><font style="color: rgb(38, 38, 38);">a </font><font style="color: rgb(19, 19, 19);">party </font><font style="color: rgb(38, 38, 38);">has been duly executed by such Purchaser</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(38, 38, 38);">and
          when delivered by such Purchaser </font><font style="color: rgb(59, 59, 59);">in </font><font style="color: rgb(38, 38, 38);">accordance with </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">terms
          hereof, will</font><font style="font-weight: bold; color: rgb(38, 38, 38);">&#160;</font><font style="color: rgb(38, 38, 38);">constitute the valid and legally </font><font style="color: rgb(19, 19, 19);">binding </font><font style="color: rgb(38, 38, 38);">obligation </font><font style="color: rgb(19, 19, 19);">of </font><font style="color: rgb(38, 38, 38);">such Purchaser</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(19, 19, 19);">enforceable </font><font style="color: rgb(38, 38, 38);">against it in accordance with its </font><font style="color: rgb(19, 19, 19);">terms</font><font style="color: rgb(98, 98, 98);">, </font><font style="color: rgb(38, 38, 38);">except: (i) as </font><font style="color: rgb(19, 19, 19);">limited by </font><font style="color: rgb(38, 38, 38);">general equitable </font><font style="color: rgb(19, 19, 19);">principles </font><font style="color: rgb(38, 38, 38);">and applicable bankruptcy, </font><font style="color: rgb(19, 19, 19);">insolvency, </font><font style="color: rgb(38, 38, 38);">reorganization, moratorium and other </font><font style="color: rgb(19, 19, 19);">laws </font><font style="color: rgb(38, 38, 38);">of general application
          affecting enforcement of creditors' rights generally</font><font style="color: rgb(80, 80, 80);">,</font><font style="color: rgb(38, 38, 38);">(ii) as </font><font style="color: rgb(19, 19, 19);">limited </font><font style="color: rgb(38, 38, 38);">by </font><font style="color: rgb(19, 19, 19);">laws </font><font style="color: rgb(38, 38, 38);">relating to the availability of </font><font style="color: rgb(59, 59, 59);">specific </font><font style="color: rgb(38, 38, 38);">performance,





          injunctive relief </font><font style="color: rgb(59, 59, 59);">or </font><font style="color: rgb(38, 38, 38);">other </font><font style="color: rgb(19, 19, 19);">equitable remedies </font><font style="color: rgb(38, 38, 38);">and </font><font style="color: rgb(19, 19, 19);">(iii) </font><font style="color: rgb(38, 38, 38);">insofar as </font><font style="color: rgb(19, 19, 19);">indemnification </font><font style="color: rgb(38, 38, 38);">and </font><font style="color: rgb(19, 19, 19);">contribution </font><font style="color: rgb(38, 38, 38);">provisions may be limited by applicable </font><font style="color: rgb(19, 19, 19);">law.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(b)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(38, 38, 38);"><u>Understandings or </u></font><font style="color: rgb(19, 19, 19);"><u>Arrangements</u></font><font style="color: rgb(80, 80, 80);">. </font><font style="color: rgb(38, 38, 38);">Such Purchaser </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">acquiring the </font><font style="color: rgb(19, 19, 19);">Securities </font><font style="color: rgb(38, 38, 38);">as principal for </font><font style="color: rgb(19, 19, 19);">its </font><font style="color: rgb(38, 38, 38);">own account and has no direct or </font><font style="color: rgb(19, 19, 19);">indirect </font><font style="color: rgb(38, 38, 38);">arrangement or understandings with any other </font><font style="color: rgb(19, 19, 19);">persons to </font><font style="color: rgb(38, 38, 38);">distribute or regarding the
          distribution </font><font style="color: rgb(19, 19, 19);">of </font><font style="color: rgb(38, 38, 38);">such </font><font style="color: rgb(19, 19, 19);">Securities (this </font><font style="color: rgb(59, 59, 59);">representation </font><font style="color: rgb(38, 38, 38);">and warranty </font><font style="color: rgb(59, 59, 59);">not </font><font style="color: rgb(38, 38, 38);">limiting such Purchaser's </font><font style="color: rgb(59, 59, 59);">right to sell the </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(38, 38, 38);"> pursuant to the Registration Statement or </font><font style="color: rgb(59, 59, 59);">otherwise </font><font style="color: rgb(38, 38, 38);">in compliance
          with applicable federal and state securities </font><font style="color: rgb(19, 19, 19);">laws)</font><font style="color: rgb(80, 80, 80);">. </font><font style="color: rgb(19, 19, 19);">Such </font><font style="color: rgb(38, 38, 38);">Purchaser





        </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">acqui</font><font style="color: rgb(80, 80, 80);">r</font><font style="color: rgb(38, 38, 38);">ing the </font><font style="color: rgb(19, 19, 19);">Securities





        </font><font style="color: rgb(38, 38, 38);">hereunder in the ordinary course of </font><font style="color: rgb(19, 19, 19);">its </font><font style="color: rgb(38, 38, 38);">business.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(19, 19, 19);">(c)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: rgb(38, 38, 38);"><u>Purchaser Status</u></font><font style="color: rgb(80, 80, 80);">. </font><font style="color: rgb(19, 19, 19);">At the </font><font style="color: rgb(38, 38, 38);">time such Purchaser was </font><font style="color: rgb(19, 19, 19);">offered </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(38, 38, 38);">, </font><font style="color: rgb(19, 19, 19);">it </font><font style="color: rgb(38, 38, 38);">was, and as of the date </font><font style="color: rgb(19, 19, 19);">hereof </font><font style="color: rgb(59, 59, 59);">it </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">either</font><font style="color: rgb(80, 80, 80);">: </font><font style="color: rgb(38, 38, 38);">(i) an </font><font style="color: rgb(98, 98, 98);">&#8220;</font><font style="color: rgb(38, 38, 38);">accredited </font><font style="color: rgb(19, 19, 19);">investor</font><font style="color: rgb(80, 80, 80);">&#8221; </font><font style="color: rgb(38, 38, 38);">as defined </font><font style="color: rgb(19, 19, 19);">in Rule </font><font style="color: rgb(38, 38, 38);">501(a)(1), (a)(2), (a)(3), </font><font style="color: rgb(19, 19, 19);">(a)(7)</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(38, 38, 38);">(a)(8) or (a)(9) </font><font style="color: rgb(19, 19, 19);">under </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">Securities Act </font><font style="color: rgb(38, 38, 38);">or
          (ii) a </font><font style="color: rgb(80, 80, 80);">&#8220;</font><font style="color: rgb(38, 38, 38);">qualified </font><font style="color: rgb(19, 19, 19);">institutional </font><font style="color: rgb(38, 38, 38);">buyer</font><font style="color: rgb(80, 80, 80);">&#8221; </font><font style="color: rgb(38, 38, 38);">as defined </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">Rule 144A(a) under the </font><font style="color: rgb(19, 19, 19);">Securities





        </font><font style="color: rgb(38, 38, 38);">Act.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(d)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <u></u><font style="color: rgb(38, 38, 38);"><u>Experience of Such Purchaser</u>. Such Purchaser, either alone or together with its
          representatives, has such knowledge, sophistication and experience </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">business and financial matters so as to be </font><font style="color: rgb(19, 19, 19);">capable </font><font style="color: rgb(38, 38, 38);">of evaluating </font><font style="color: rgb(19, 19, 19);">the merits </font><font style="color: rgb(38, 38, 38);">and risks of </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">prospective </font><font style="color: rgb(19, 19, 19);">investment </font><font style="color: rgb(38, 38, 38);">in </font><font style="color: rgb(19, 19, 19);">the Securities</font><font style="color: rgb(38, 38, 38);">, and has so evaluated the merits and risks of such </font><font style="color: rgb(19, 19, 19);">investment. </font><font style="color: rgb(38, 38, 38);">Such Purchaser </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">able to bear the economic risk of an </font><font style="color: rgb(19, 19, 19);">investment in the Securities</font><font style="color: rgb(38, 38, 38);"> and</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(38, 38, 38);">a</font><font style="color: rgb(80, 80, 80);">t </font><font style="color: rgb(19, 19, 19);">the present </font><font style="color: rgb(38, 38, 38);">time, is able to afford a complete </font><font style="color: rgb(19, 19, 19);">loss </font><font style="color: rgb(38, 38, 38);">of such </font><font style="color: rgb(19, 19, 19);">investment.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(e)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(38, 38, 38);"><u>Access to </u></font><font style="color: rgb(19, 19, 19);"><u>Information</u>. </font><font style="color: rgb(38, 38, 38);">Such Purchaser acknowledges that </font><font style="color: rgb(59, 59, 59);">it </font><font style="color: rgb(38, 38, 38);">has had the opportunity to review the Transaction </font><font style="color: rgb(19, 19, 19);">Documents (including </font><font style="color: rgb(38, 38, 38);">all exhibits and schedules thereto) and the SEC Reports and has been afforded, (i) the opportunity </font><font style="color: rgb(59, 59, 59);">to </font><font style="color: rgb(38, 38, 38);">ask such questions as </font><font style="color: rgb(19, 19, 19);">it </font><font style="color: rgb(59, 59, 59);">has </font><font style="color: rgb(19, 19, 19);">deemed </font><font style="color: rgb(38, 38, 38);">necessary of, and to receive answers from, representatives of the </font><font style="color: rgb(19, 19, 19);">Company </font><font style="color: rgb(38, 38, 38);">concerning the terms and conditions of the offering </font><font style="color: rgb(19, 19, 19);">of </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">Securities </font><font style="color: rgb(38, 38, 38);">and </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">merits and </font><font style="color: rgb(19, 19, 19);">risks </font><font style="color: rgb(38, 38, 38);">of </font><font style="color: rgb(19, 19, 19);">investing in </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(38, 38, 38);">; (ii) access to </font><font style="color: rgb(19, 19, 19);">information </font><font style="color: rgb(38, 38, 38);">about </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Company and </font><font style="color: rgb(59, 59, 59);">its </font><font style="color: rgb(19, 19, 19);">financial </font><font style="color: rgb(59, 59, 59);">condition,





        </font><font style="color: rgb(38, 38, 38);">results of operations</font><font style="color: rgb(80, 80, 80);">, </font><font style="color: rgb(38, 38, 38);">business, </font><font style="color: rgb(19, 19, 19);">properties, management </font><font style="color: rgb(38, 38, 38);">and </font><font style="color: rgb(19, 19, 19);">prospects </font><font style="color: rgb(38, 38, 38);">sufficient </font><font style="color: rgb(19, 19, 19);">to </font><font style="color: rgb(38, 38, 38);">enable





        </font><font style="color: rgb(19, 19, 19);">it to </font><font style="color: rgb(38, 38, 38);">evaluate </font><font style="color: rgb(19, 19, 19);">its investment: </font><font style="color: rgb(38, 38, 38);">and (iii) the opportunity to
          obtain such additional </font><font style="color: rgb(19, 19, 19);">information that </font><font style="color: rgb(38, 38, 38);">the Company possesses </font><font style="color: rgb(19, 19, 19);">or </font><font style="color: rgb(38, 38, 38);">can acquire without unreasonable </font><font style="color: rgb(19, 19, 19);">effort or expense </font><font style="color: rgb(38, 38, 38);">that is </font><font style="color: rgb(21, 21, 21);">necessary </font><font style="color: rgb(38, 38, 38);">to make an </font><font style="color: rgb(21, 21, 21);">informed investment </font><font style="color: rgb(38, 38, 38);">decision with </font><font style="color: rgb(21, 21, 21);">respect </font><font style="color: rgb(58, 58, 58);">to </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(21, 21, 21);">investment.</font></div>
      <div><br>
      </div>
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      <div style="text-indent: 72pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">(f)</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(38, 38, 38);"><u>Certain Transactions and Confidentiality</u></font><font style="color: rgb(79, 79, 79);">. </font><font style="color: rgb(38, 38, 38);">Other </font><font style="color: rgb(21, 21, 21);">than </font><font style="color: rgb(38, 38, 38);">consummating the transactions contemplated </font><font style="color: rgb(21, 21, 21);">hereunder, </font><font style="color: rgb(38, 38, 38);">such Purchaser has not, </font><font style="color: rgb(21, 21, 21);">nor </font><font style="color: rgb(38, 38, 38);">has any Person acting on behalf of </font><font style="color: rgb(21, 21, 21);">or </font><font style="color: rgb(38, 38, 38);">pursuant to any </font><font style="color: rgb(21, 21, 21);">understanding </font><font style="color: rgb(38, 38, 38);">with </font><font style="color: rgb(21, 21, 21);">such </font><font style="color: rgb(38, 38, 38);">Purchaser, directly or </font><font style="color: rgb(21, 21, 21);">indirectly </font><font style="color: rgb(38, 38, 38);">executed any </font><font style="color: rgb(21, 21, 21);">purchases </font><font style="color: rgb(38, 38, 38);">or </font><font style="color: rgb(21, 21, 21);">sales</font><font style="color: rgb(94, 94, 94);">, </font><font style="color: rgb(21, 21, 21);">including </font><font style="color: rgb(38, 38, 38);">Short Sales, </font><font style="color: rgb(21, 21, 21);">of </font><font style="color: rgb(38, 38, 38);">the securities </font><font style="color: rgb(21, 21, 21);">of the Company </font><font style="color: rgb(58, 58, 58);">during </font><font style="color: rgb(38, 38, 38);">the period commencing as of the </font><font style="color: rgb(21, 21, 21);">time </font><font style="color: rgb(58, 58, 58);">that </font><font style="color: rgb(38, 38, 38);">such Purchaser first received notice </font><font style="color: rgb(21, 21, 21);">of </font><font style="color: rgb(58, 58, 58);">the </font><font style="color: rgb(38, 38, 38);">transaction </font><font style="color: rgb(58, 58, 58);">contemplated hereunder </font><font style="color: rgb(38, 38, 38);">(written or oral) from the </font><font style="color: rgb(21, 21, 21);">Company </font><font style="color: rgb(38, 38, 38);">or any other Person </font><font style="color: rgb(58, 58, 58);">representing </font><font style="color: rgb(38, 38, 38);">the Company </font><font style="color: rgb(58, 58, 58);">and </font><font style="color: rgb(21, 21, 21);">ending </font><font style="color: rgb(58, 58, 58);">immediately </font><font style="color: rgb(38, 38, 38);">prior </font><font style="color: rgb(21, 21, 21);">to </font><font style="color: rgb(38, 38, 38);">the execution hereof. Notwithstanding the </font><font style="color: rgb(21, 21, 21);">foregoing</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(21, 21, 21);">in </font><font style="color: rgb(38, 38, 38);">the case of a Purchaser </font><font style="color: rgb(58, 58, 58);">that </font><font style="color: rgb(38, 38, 38);">is a multi-managed </font><font style="color: rgb(21, 21, 21);">investment vehicle </font><font style="color: rgb(38, 38, 38);">whereby separate portfolio managers manage separate portions </font><font style="color: rgb(21, 21, 21);">of </font><font style="color: rgb(38, 38, 38);">such </font><font style="color: rgb(21, 21, 21);">Purchaser's </font><font style="color: rgb(38, 38, 38);">assets and the portfolio managers have </font><font style="color: rgb(58, 58, 58);">no </font><font style="color: rgb(38, 38, 38);">direct knowledge of the investment decisions made by </font><font style="color: rgb(58, 58, 58);">the </font><font style="color: rgb(38, 38, 38);">portfolio managers </font><font style="color: rgb(58, 58, 58);">managing </font><font style="color: rgb(38, 38, 38);">other portions of such Purchaser</font><font style="color: rgb(94, 94, 94);">'</font><font style="color: rgb(38, 38, 38);">s assets, the representation set forth above shall </font><font style="color: rgb(21, 21, 21);">only </font><font style="color: rgb(38, 38, 38);">apply with respect to </font><font style="color: rgb(21, 21, 21);">the </font><font style="color: rgb(38, 38, 38);">portion </font><font style="color: rgb(21, 21, 21);">of </font><font style="color: rgb(38, 38, 38);">assets managed </font><font style="color: rgb(21, 21, 21);">by </font><font style="color: rgb(38, 38, 38);">the portfolio manager </font><font style="color: rgb(21, 21, 21);">that </font><font style="color: rgb(38, 38, 38);">made </font><font style="color: rgb(21, 21, 21);">the </font><font style="color: rgb(38, 38, 38);">investment decision </font><font style="color: rgb(21, 21, 21);">to </font><font style="color: rgb(38, 38, 38);">purchase the
        </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(38, 38, 38);"> covered by this </font><font style="color: rgb(21, 21, 21);">Agreement. </font><font style="color: rgb(38, 38, 38);">Other than to other Persons
          party </font><font style="color: rgb(21, 21, 21);">to </font><font style="color: rgb(38, 38, 38);">this Agreement </font><font style="color: rgb(58, 58, 58);">or to such </font><font style="color: rgb(38, 38, 38);">Purchaser</font><font style="color: rgb(79, 79, 79);">'s </font><font style="color: rgb(58, 58, 58);">representatives, </font><font style="color: rgb(38, 38, 38);">including, without limi</font><font style="color: rgb(79, 79, 79);">t</font><font style="color: rgb(38, 38, 38);">ation</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(58, 58, 58);">its </font><font style="color: rgb(38, 38, 38);">officers, directors, partners, </font><font style="color: rgb(21, 21, 21);">legal





        </font><font style="color: rgb(38, 38, 38);">and other advisors, </font><font style="color: rgb(58, 58, 58);">employees, </font><font style="color: rgb(38, 38, 38);">agents </font><font style="color: rgb(58, 58, 58);">and </font><font style="color: rgb(21, 21, 21);">Affiliates, </font><font style="color: rgb(38, 38, 38);">such </font><font style="color: rgb(58, 58, 58);">Purchaser </font><font style="color: rgb(38, 38, 38);">has maintained the confidentiality of all </font><font style="color: rgb(21, 21, 21);">disclosures </font><font style="color: rgb(38, 38, 38);">made to </font><font style="color: rgb(21, 21, 21);">it </font><font style="color: rgb(58, 58, 58);">in </font><font style="color: rgb(38, 38, 38);">connection





          with this </font><font style="color: rgb(21, 21, 21);">transaction (including </font><font style="color: rgb(38, 38, 38);">the existence and terms of </font><font style="color: rgb(21, 21, 21);">this </font><font style="color: rgb(38, 38, 38);">transaction).</font></div>
      <div><br>
      </div>
      <div style="text-align: center;"><font style="color: rgb(36, 36, 36);">ARTICLE </font><font style="color: rgb(15, 15, 15);">IV.</font></div>
      <div style="text-align: center; color: rgb(36, 36, 36);">OTHER AGREEMENTS OF THE PARTIES</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">4.1</font>&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Furnishing of </u></font><font style="color: rgb(15, 15, 15);"><u>Information</u></font><font style="color: rgb(63, 63, 63);">. </font><font style="color: rgb(36, 36, 36);">Until the time that no Purchaser owns </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(36, 36, 36);">, the Company covenants to
          timely file (or obtain extensions in respect thereof and file within the applicable grace period) all reports required to be filed by the Company after the date hereof pursuant to the </font><font style="color: rgb(15, 15, 15);">Exchange </font><font style="color: rgb(36, 36, 36);">Act, provided that the Company is then subject to the reporting </font><font style="color: rgb(15, 15, 15);">requirements </font><font style="color: rgb(36, 36, 36);">of the Exchange Act.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">4.2</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(15, 15, 15);"><u>I</u></font><font style="color: rgb(63, 63, 63);"><u>n</u></font><font style="color: rgb(36, 36, 36);"><u>tegr</u></font><font style="color: rgb(63, 63, 63);"><u>a</u></font><font style="color: rgb(36, 36, 36);"><u>tion</u>. The Company shall not sell, offer for sale or solicit offers to buy or otherwise negotiate </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">respect of any security (as defined </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">Section 2 of</font><font style="font-weight: bold; color: rgb(36, 36, 36);">&#160;</font><font style="color: rgb(36, 36, 36);">the Securities Act) that would be </font><font style="color: rgb(15, 15, 15);">integrated </font><font style="color: rgb(36, 36, 36);">with the offer </font><font style="color: rgb(15, 15, 15);">or </font><font style="color: rgb(36, 36, 36);">sale of the </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(36, 36, 36);">&#160;</font><font style="color: rgb(15, 15, 15);">for </font><font style="color: rgb(36, 36, 36);">purposes of the rules and regulations of any Trading Market such that </font><font style="color: rgb(15, 15, 15);">it </font><font style="color: rgb(36, 36, 36);">would </font><font style="color: rgb(15, 15, 15);">requ</font><font style="color: rgb(63, 63, 63);">i</font><font style="color: rgb(36, 36, 36);">re shareholder approval prior to the closing of such other transaction unless shareholder approval is obtained before the closing of such
          subsequent transaction.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">4.3</font>&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Securities Laws Disclosure; Publicity</u>. </font><font style="color: rgb(63, 63, 63);">The </font><font style="color: rgb(36, 36, 36);">Company shall file a Current Report on Form 8-K, </font><font style="color: rgb(15, 15, 15);">including </font><font style="color: rgb(36, 36, 36);">the Transaction Documents as exhibits thereto, with the
          Commission within the time required by the Exchange Act. The Company shall not publicly disclose the name of any Purchaser, or include the name of any Purchaser in any filing with the Commission or any regulatory agency or Trading Market, without
          the prior written consent of such Purchaser, except (a) as required by federal securities law in connection with the filing of final Transaction Documents with the Commission, (b) to the extent such disclosure is required by law or Trading Market
          regulations, in which case the Company shall, to the extent permitted by law, provide the Purchasers with prior notice of such disclosure permitted under this clause (b), and (c) where such name has otherwise been publicly disclosed other than by
          the Company.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">4.4</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Use of Proceeds</u>. The Company intends </font><font style="color: rgb(15, 15, 15);">to </font><font style="color: rgb(36, 36, 36);">use the net proceeds from </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(36, 36, 36);">sale </font><font style="color: rgb(56, 56, 56);">of </font><font style="color: rgb(36, 36, 36);">the </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(36, 36, 36);"> hereunder for </font><font style="color: rgb(15, 15, 15);">research</font><font style="color: rgb(56, 56, 56);">, </font><font style="color: rgb(36, 36, 36);">development</font><font style="color: rgb(79, 79, 79);">, </font><font style="color: rgb(36, 36, 36);">working capital</font><font style="color: rgb(112, 112, 112);">, </font><font style="color: rgb(36, 36, 36);">and





          other general corporate purposes.</font></div>
      <div><br>
      </div>
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      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">4.5</font>&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Indemnification of Purchasers</u>. Subject to the provisions of this Section 4.5, the Company will
          indemnify and hold each Purchaser and its directors, officers, shareholders, members, partners, employees and agents (and any other Persons with a functionally equivalent role of a Person holding such titles notwithstanding a lack of such title
          or any other title), each Person who controls such Purchaser (within the meaning of Section 15 of the Securities Act and Section 20 of the Exchange Act), and the directors, officers, shareholders, agents, members, partners or employees (and any
          other Persons with a functionally equivalent role of a Person holding such titles notwithstanding a lack of such title or any other title) of such controlling persons (each, a &#8220;Purchaser Party&#8221;) harmless from any and all losses, liabilities,
          obligations, claims, contingencies, damages, costs and expenses, including all judgments, amounts paid in settlements, court costs and reasonable attorneys&#8217; fees and costs of investigation that any such Purchaser Party may suffer or incur as a
          result of or relating to (a) any breach of any of the representations, warranties, covenants or agreements made by the Company in this Agreement or in the other Transaction Documents or (b) any action instituted against the Purchaser Parties in
          any capacity, or any of them or their respective Affiliates, by any stockholder of the Company who is not an Affiliate of such Purchaser Party, with respect to any of the transactions contemplated by the Transaction Documents (unless such action
          is solely based upon a material breach of such Purchaser Party&#8217;s representations, warranties or covenants under the Transaction Documents or any agreements or understandings such Purchaser Party may have with any such stockholder or any
          violations by such Purchaser Party of state or federal securities laws or any conduct by such Purchaser Party which is finally judicially determined to constitute fraud, gross negligence or willful misconduct). If any action shall be brought
          against any Purchaser Party in respect of which indemnity may be sought pursuant to this Agreement, such Purchaser Party shall promptly notify the Company in writing, and the Company shall have the right to assume the defense thereof with counsel
          of its own choosing reasonably acceptable to the Purchaser Party. Any Purchaser Party shall have the right to employ separate counsel in any such action and participate in the defense thereof, but the fees and expenses of such counsel shall be at
          the expense of such Purchaser Party except to the extent that (i) the employment thereof has been specifically authorized by the Company in writing, (ii) the Company has failed after a reasonable period of time to assume such defense and to
          employ counsel or (iii) in such action there is, in the reasonable opinion of counsel, a material conflict on any material issue between the position of the Company and the position of such Purchaser Party, in which case the Company shall be
          responsible for the reasonable fees and expenses of no more than one such separate counsel for all the Purchasers. The Company will not be liable to any Purchaser Party under this Agreement (y) for any settlement or consent to the entry of any
          judgment by a Purchaser Party effected without the Company&#8217;s prior written consent, which shall not be unreasonably withheld or delayed; or (z) to the extent, but only to the extent that a loss, claim, damage or liability is attributable to any
          Purchaser Party&#8217;s breach of any of the representations, warranties, covenants or agreements made by such Purchaser Party in this Agreement or in the other Transaction Documents. The indemnity agreements contained herein shall be in addition to
          any cause of action or similar right of any Purchaser Party against the Company or others and any liabilities the Company may be subject to pursuant to law.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(19, 19, 19);">4.6</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(38, 38, 38);"><u>Listing of </u></font><font style="color: rgb(19, 19, 19);"><u>Common </u></font><font style="color: rgb(38, 38, 38);"><u>Stock</u></font><font style="color: rgb(82, 82, 82);">. </font><font style="color: rgb(38, 38, 38);">The Company hereby agrees to use commercially </font><font style="color: rgb(19, 19, 19);">reasonable </font><font style="color: rgb(38, 38, 38);">efforts to </font><font style="color: rgb(19, 19, 19);">maintain </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">listing </font><font style="color: rgb(38, 38, 38);">or quotation of the </font><font style="color: rgb(19, 19, 19);">Common Stock </font><font style="color: rgb(38, 38, 38);">on the Trading Market on which </font><font style="color: rgb(19, 19, 19);">it is currently listed, </font><font style="color: rgb(38, 38, 38);">and concurrently with the </font><font style="color: rgb(19, 19, 19);">Closing, </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">Company shall </font><font style="color: rgb(38, 38, 38);">apply to list or </font><font style="color: rgb(19, 19, 19);">quote </font><font style="color: rgb(38, 38, 38);">all of the Shares and the Pre-Funded</font><font style="color: rgb(0, 0, 0);"> Warrant Shares</font><font style="color: rgb(38, 38, 38);"> on such Trading Market and promptly secure </font><font style="color: rgb(19, 19, 19);">the listing </font><font style="color: rgb(38, 38, 38);">of all of </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Shares and the Pre-Funded</font><font style="color: rgb(0, 0, 0);"> Warrant Shares</font><font style="color: rgb(19, 19, 19);"> on </font><font style="color: rgb(38, 38, 38);">such Trading Market. The Company </font><font style="color: rgb(19, 19, 19);">further </font><font style="color: rgb(38, 38, 38);">agrees, </font><font style="color: rgb(19, 19, 19);">if </font><font style="color: rgb(38, 38, 38);">the Company applies to have the Common Stock traded on
          any other Trading Market, </font><font style="color: rgb(19, 19, 19);">it </font><font style="color: rgb(38, 38, 38);">will then </font><font style="color: rgb(19, 19, 19);">include in </font><font style="color: rgb(38, 38, 38);">such
          application all of the </font><font style="color: rgb(19, 19, 19);">Shares and the </font><font style="color: rgb(38, 38, 38);">Pre-Funded</font><font style="color: rgb(0, 0, 0);"> Warrant Shares</font><font style="color: rgb(19, 19, 19);">, </font><font style="color: rgb(38, 38, 38);">and will take such </font><font style="color: rgb(19, 19, 19);">other </font><font style="color: rgb(38, 38, 38);">action as is reasonably necessary to cause all of the Shares and the Pre-Funded</font><font style="color: rgb(0, 0, 0);"> Warrant Shares</font><font style="color: rgb(19, 19, 19);"> to </font><font style="color: rgb(38, 38, 38);">be </font><font style="color: rgb(19, 19, 19);">listed </font><font style="color: rgb(38, 38, 38);">or
          quoted </font><font style="color: rgb(19, 19, 19);">on </font><font style="color: rgb(38, 38, 38);">such </font><font style="color: rgb(19, 19, 19);">other </font><font style="color: rgb(38, 38, 38);">Trading </font><font style="color: rgb(19, 19, 19);">Market </font><font style="color: rgb(38, 38, 38);">as promptly as possible. The </font><font style="color: rgb(19, 19, 19);">Company </font><font style="color: rgb(38, 38, 38);">will then take all action </font><font style="color: rgb(19, 19, 19);">reasonably </font><font style="color: rgb(38, 38, 38);">necessary </font><font style="color: rgb(19, 19, 19);">to </font><font style="color: rgb(38, 38, 38);">continue the listing and </font><font style="color: rgb(19, 19, 19);">trading of </font><font style="color: rgb(38, 38, 38);">its Common </font><font style="color: rgb(19, 19, 19);">Stock on </font><font style="color: rgb(38, 38, 38);">a Trading Market and will comply </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">all respects with the Company's </font><font style="color: rgb(19, 19, 19);">reporting, filing </font><font style="color: rgb(38, 38, 38);">and other obligations
          of which </font><font style="color: rgb(19, 19, 19);">it </font><font style="color: rgb(38, 38, 38);">has control under the bylaws or rules of the Trading Market. The Company agrees </font><font style="color: rgb(19, 19, 19);">to </font><font style="color: rgb(38, 38, 38);">maintain the </font><font style="color: rgb(19, 19, 19);">eligibility </font><font style="color: rgb(38, 38, 38);">of the Common Stock </font><font style="color: rgb(19, 19, 19);">for </font><font style="color: rgb(38, 38, 38);">electronic transfer through the </font><font style="color: rgb(19, 19, 19);">Depository Trust Company </font><font style="color: rgb(38, 38, 38);">or another established </font><font style="color: rgb(19, 19, 19);">clearing </font><font style="color: rgb(38, 38, 38);">corporation, </font><font style="color: rgb(19, 19, 19);">including, </font><font style="color: rgb(38, 38, 38);">without </font><font style="color: rgb(19, 19, 19);">limitation, by timely payment </font><font style="color: rgb(38, 38, 38);">of </font><font style="color: rgb(19, 19, 19);">fees to </font><font style="color: rgb(38, 38, 38);">the Depository </font><font style="color: rgb(19, 19, 19);">Trust Company </font><font style="color: rgb(38, 38, 38);">or such </font><font style="color: rgb(19, 19, 19);">other </font><font style="color: rgb(38, 38, 38);">established clearing corporation </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">connection





          with such electronic transfer.</font></div>
      <div><br>
      </div>
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      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(24, 24, 24);">4.7</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(24, 24, 24);"><u>Certain </u></font><font style="color: rgb(40, 40, 40);"><u>Transactions and Confidentiality</u>.
          Each Purchaser, severally and not </font><font style="color: rgb(24, 24, 24);">jointly </font><font style="color: rgb(40, 40, 40);">with the other Purchasers, covenants </font><font style="color: rgb(24, 24, 24);">that </font><font style="color: rgb(40, 40, 40);">neither </font><font style="color: rgb(24, 24, 24);">it </font><font style="color: rgb(40, 40, 40);">nor any </font><font style="color: rgb(24, 24, 24);">Affiliate </font><font style="color: rgb(40, 40, 40);">acting





          on </font><font style="color: rgb(24, 24, 24);">its </font><font style="color: rgb(40, 40, 40);">behalf or </font><font style="color: rgb(24, 24, 24);">pursuant </font><font style="color: rgb(40, 40, 40);">to any </font><font style="color: rgb(24, 24, 24);">understanding </font><font style="color: rgb(40, 40, 40);">with </font><font style="color: rgb(24, 24, 24);">it </font><font style="color: rgb(40, 40, 40);">will execute any purchases or sales, </font><font style="color: rgb(24, 24, 24);">including </font><font style="color: rgb(40, 40, 40);">Short </font><font style="color: rgb(24, 24, 24);">Sales </font><font style="color: rgb(40, 40, 40);">of any </font><font style="color: rgb(24, 24, 24);">of </font><font style="color: rgb(40, 40, 40);">the Company's </font><font style="color: rgb(66, 66, 66);">securities </font><font style="color: rgb(24, 24, 24);">during the </font><font style="color: rgb(40, 40, 40);">period </font><font style="color: rgb(24, 24, 24);">commencing </font><font style="color: rgb(40, 40, 40);">with </font><font style="color: rgb(24, 24, 24);">the </font><font style="color: rgb(40, 40, 40);">execution </font><font style="color: rgb(24, 24, 24);">of this
          Agreement </font><font style="color: rgb(40, 40, 40);">and ending </font><font style="color: rgb(24, 24, 24);">at </font><font style="color: rgb(40, 40, 40);">such time that </font><font style="color: rgb(24, 24, 24);">the </font><font style="color: rgb(40, 40, 40);">transactions contemplated by this </font><font style="color: rgb(24, 24, 24);">Agreement are first publicly </font><font style="color: rgb(40, 40, 40);">announced pursuant </font><font style="color: rgb(24, 24, 24);">to </font><font style="color: rgb(40, 40, 40);">the </font><font style="color: rgb(36, 36, 36);">Current Report on Form 8-K</font><font style="color: rgb(40, 40, 40);"> as </font><font style="color: rgb(24, 24, 24);">described in </font><font style="color: rgb(40, 40, 40);">Section 4.3. Each Purchaser, severally and </font><font style="color: rgb(24, 24, 24);">not </font><font style="color: rgb(40, 40, 40);">jointly with </font><font style="color: rgb(24, 24, 24);">the other </font><font style="color: rgb(40, 40, 40);">Purchasers, </font><font style="color: rgb(24, 24, 24);">covenants </font><font style="color: rgb(40, 40, 40);">that </font><font style="color: rgb(24, 24, 24);">u</font><font style="color: rgb(66, 66, 66);">n</font><font style="color: rgb(40, 40, 40);">til such time as the transactions </font><font style="color: rgb(24, 24, 24);">contemplated </font><font style="color: rgb(40, 40, 40);">by this </font><font style="color: rgb(24, 24, 24);">Agreement </font><font style="color: rgb(40, 40, 40);">are publicly disclosed </font><font style="color: rgb(24, 24, 24);">by </font><font style="color: rgb(40, 40, 40);">the </font><font style="color: rgb(24, 24, 24);">Company </font><font style="color: rgb(40, 40, 40);">pursuant </font><font style="color: rgb(24, 24, 24);">to </font><font style="color: rgb(40, 40, 40);">the </font><font style="color: rgb(36, 36, 36);">Current Report on Form 8-K</font><font style="color: rgb(24, 24, 24);">&#160;</font><font style="color: rgb(40, 40, 40);">as </font><font style="color: rgb(24, 24, 24);">described </font><font style="color: rgb(40, 40, 40);">in </font><font style="color: rgb(24, 24, 24);">Section </font><font style="color: rgb(40, 40, 40);">4</font><font style="color: rgb(89, 89, 89);">.</font><font style="color: rgb(40, 40, 40);">3</font><font style="color: rgb(89, 89, 89);">, </font><font style="color: rgb(40, 40, 40);">such Purchaser will </font><font style="color: rgb(24, 24, 24);">maintain
        </font><font style="color: rgb(40, 40, 40);">the </font><font style="color: rgb(24, 24, 24);">confidentiality </font><font style="color: rgb(40, 40, 40);">of </font><font style="color: rgb(24, 24, 24);">the </font><font style="color: rgb(40, 40, 40);">existence and terms of </font><font style="color: rgb(24, 24, 24);">this </font><font style="color: rgb(40, 40, 40);">transaction</font><font style="color: rgb(89, 89, 89);">. </font><font style="color: rgb(24, 24, 24);">Notwithstanding





        </font><font style="color: rgb(40, 40, 40);">the </font><font style="color: rgb(24, 24, 24);">forego</font><font style="color: rgb(66, 66, 66);">i</font><font style="color: rgb(24, 24, 24);">ng</font><font style="color: rgb(66, 66, 66);">, and </font><font style="color: rgb(40, 40, 40);">notwithstanding anything contained </font><font style="color: rgb(24, 24, 24);">in </font><font style="color: rgb(40, 40, 40);">this </font><font style="color: rgb(24, 24, 24);">Agreement </font><font style="color: rgb(40, 40, 40);">to </font><font style="color: rgb(24, 24, 24);">the </font><font style="color: rgb(40, 40, 40);">cont</font><font style="color: rgb(66, 66, 66);">r</font><font style="color: rgb(40, 40, 40);">ary</font><font style="color: rgb(89, 89, 89);">, </font><font style="color: rgb(40, 40, 40);">the </font><font style="color: rgb(24, 24, 24);">Com</font><font style="color: rgb(66, 66, 66);">p</font><font style="color: rgb(40, 40, 40);">any expressly
          acknowledges and agrees that </font><font style="color: rgb(24, 24, 24);">(i) no </font><font style="color: rgb(40, 40, 40);">Purchaser makes any representation, warranty or covenant hereby that </font><font style="color: rgb(24, 24, 24);">it
        </font><font style="color: rgb(40, 40, 40);">will not engage in effecting </font><font style="color: rgb(24, 24, 24);">transactions </font><font style="color: rgb(40, 40, 40);">in any </font><font style="color: rgb(24, 24, 24);">securities </font><font style="color: rgb(40, 40, 40);">of </font><font style="color: rgb(24, 24, 24);">the Company </font><font style="color: rgb(40, 40, 40);">after the time that </font><font style="color: rgb(24, 24, 24);">the </font><font style="color: rgb(40, 40, 40);">transactions contemplated by this </font><font style="color: rgb(24, 24, 24);">Agreement </font><font style="color: rgb(40, 40, 40);">are </font><font style="color: rgb(24, 24, 24);">first </font><font style="color: rgb(40, 40, 40);">publicly announced </font><font style="color: rgb(24, 24, 24);">pursuant to the </font><font style="color: rgb(36, 36, 36);">Current Report on Form 8-K</font><font style="color: rgb(40, 40, 40);">&#160;</font><font style="color: rgb(66, 66, 66);">as </font><font style="color: rgb(40, 40, 40);">described </font><font style="color: rgb(24, 24, 24);">in </font><font style="color: rgb(40, 40, 40);">Section 4.3, (ii) </font><font style="color: rgb(24, 24, 24);">no Purchaser </font><font style="color: rgb(40, 40, 40);">shal</font><font style="color: rgb(24, 24, 24);">l </font><font style="color: rgb(40, 40, 40);">be restricted or prohibited </font><font style="color: rgb(24, 24, 24);">from </font><font style="color: rgb(40, 40, 40);">effecting any transactions </font><font style="color: rgb(24, 24, 24);">in </font><font style="color: rgb(40, 40, 40);">any securities of the Company </font><font style="color: rgb(24, 24, 24);">in </font><font style="color: rgb(40, 40, 40);">accordance with applicable securities </font><font style="color: rgb(24, 24, 24);">laws </font><font style="color: rgb(40, 40, 40);">from and after the </font><font style="color: rgb(66, 66, 66);">t</font><font style="color: rgb(24, 24, 24);">ime </font><font style="color: rgb(40, 40, 40);">that the transactions contemplated by this </font><font style="color: rgb(24, 24, 24);">Agreement </font><font style="color: rgb(40, 40, 40);">are first publicly announced pursuant to
          the </font><font style="color: rgb(36, 36, 36);">Current Report on Form 8-K</font><font style="color: rgb(66, 66, 66);">&#160;</font><font style="color: rgb(40, 40, 40);">as described </font><font style="color: rgb(24, 24, 24);">in </font><font style="color: rgb(40, 40, 40);">Section 4.3 and (iii) no Purchaser shall have any </font><font style="color: rgb(24, 24, 24);">duty </font><font style="color: rgb(40, 40, 40);">of confidentiality or </font><font style="color: rgb(24, 24, 24);">duty





        </font><font style="color: rgb(40, 40, 40);">not </font><font style="color: rgb(24, 24, 24);">to trade in the </font><font style="color: rgb(40, 40, 40);">securities of </font><font style="color: rgb(24, 24, 24);">the Company </font><font style="color: rgb(40, 40, 40);">to the Company or </font><font style="color: rgb(24, 24, 24);">its </font><font style="color: rgb(40, 40, 40);">Subsidiaries after </font><font style="color: rgb(24, 24, 24);">the issuance </font><font style="color: rgb(40, 40, 40);">of the </font><font style="color: rgb(36, 36, 36);">Current Report on Form 8-K</font><font style="color: rgb(40, 40, 40);"> as </font><font style="color: rgb(24, 24, 24);">described in </font><font style="color: rgb(40, 40, 40);">Section 4.3. Notwithstanding the foregoing, in the case of </font><font style="color: rgb(24, 24, 24);">a Pu</font><font style="color: rgb(66, 66, 66);">r</font><font style="color: rgb(40, 40, 40);">chaser that </font><font style="color: rgb(24, 24, 24);">is </font><font style="color: rgb(40, 40, 40);">a </font><font style="color: rgb(24, 24, 24);">multi-</font><font style="color: rgb(40, 40, 40);">manager </font><font style="color: rgb(24, 24, 24);">inve</font><font style="color: rgb(66, 66, 66);">s</font><font style="color: rgb(40, 40, 40);">tment </font><font style="color: rgb(24, 24, 24);">vehicle </font><font style="color: rgb(40, 40, 40);">whereby separate </font><font style="color: rgb(66, 66, 66);">p</font><font style="color: rgb(24, 24, 24);">ortfolio </font><font style="color: rgb(40, 40, 40);">managers manage separate </font><font style="color: rgb(24, 24, 24);">portion</font><font style="color: rgb(66, 66, 66);">s </font><font style="color: rgb(24, 24, 24);">of</font><font style="font-weight: bold; color: rgb(24, 24, 24);">&#160;</font><font style="color: rgb(66, 66, 66);">such </font><font style="color: rgb(40, 40, 40);">Purchaser's </font><font style="color: rgb(66, 66, 66);">assets
          and </font><font style="color: rgb(89, 89, 89);">t</font><font style="color: rgb(40, 40, 40);">h</font><font style="color: rgb(66, 66, 66);">e </font><font style="color: rgb(40, 40, 40);">portfolio </font><font style="color: rgb(66, 66, 66);">managers





        </font><font style="color: rgb(40, 40, 40);">have </font><font style="color: rgb(66, 66, 66);">no </font><font style="color: rgb(40, 40, 40);">direct </font><font style="color: rgb(66, 66, 66);">knowledge </font><font style="color: rgb(40, 40, 40);">of the investment decisions made by the portfo</font><font style="color: rgb(89, 89, 89);">l</font><font style="color: rgb(40, 40, 40);">io managers managing </font><font style="color: rgb(66, 66, 66);">other </font><font style="color: rgb(40, 40, 40);">portions of </font><font style="color: rgb(66, 66, 66);">such </font><font style="color: rgb(40, 40, 40);">Purch</font><font style="color: rgb(66, 66, 66);">ase</font><font style="color: rgb(40, 40, 40);">r</font><font style="color: rgb(123, 123, 123);">'</font><font style="color: rgb(66, 66, 66);">s assets, the </font><font style="color: rgb(40, 40, 40);">covenant set </font><font style="color: rgb(24, 24, 24);">forth </font><font style="color: rgb(40, 40, 40);">above shall only apply with respect to the portion of assets managed by </font><font style="color: rgb(24, 24, 24);">the </font><font style="color: rgb(40, 40, 40);">portfolio </font><font style="color: rgb(24, 24, 24);">manager </font><font style="color: rgb(40, 40, 40);">that </font><font style="color: rgb(24, 24, 24);">made </font><font style="color: rgb(40, 40, 40);">the </font><font style="color: rgb(24, 24, 24);">investment </font><font style="color: rgb(40, 40, 40);">decision





        </font><font style="color: rgb(24, 24, 24);">to </font><font style="color: rgb(40, 40, 40);">purchase the </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(24, 24, 24);">&#160;</font><font style="color: rgb(40, 40, 40);">covered </font><font style="color: rgb(24, 24, 24);">by this Agreement.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(24, 24, 24);">4.8</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(24, 24, 24);"><u>Equal Treatment of Purchasers</u>. No consideration (including any modification of any Transaction
          Document) shall be offered or paid to any Person to amend or consent to a waiver or modification of any provision of the Transaction Documents unless the same consideration is also offered to all of the parties to such Transaction Document. For
          clarification purposes, this provision constitutes a separate right granted to each Purchaser by the Company and negotiated separately by each Purchaser and is intended for the Company to treat the Purchasers as a class and shall not in any way
          be construed as the Purchasers acting in concert or as a group with respect to the purchase, disposition or voting of Shares, </font><font style="color: rgb(38, 38, 38);">Pre-Funded</font><font style="color: rgb(24, 24, 24);"> Warrant Shares or
          otherwise.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(24, 24, 24);">4.9</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(0, 0, 0);"><u>Reservation of Common Stock</u>. As of the date hereof, the Company has reserved and the Company
          shall continue to reserve and keep available at all times, free of preemptive rights, a sufficient number of shares of Common Stock for the purpose of enabling the Company to issue Shares pursuant to this Agreement and </font><font style="color: rgb(38, 38, 38);">Pre-Funded</font><font style="color: rgb(0, 0, 0);"> Warrant Shares pursuant to any exercise of the </font><font style="color: rgb(38, 38, 38);">Pre-Funded</font><font style="color: rgb(0, 0, 0);"> Warrants.</font></div>
      <div><br>
      </div>
      <div style="text-align: center;"><font style="color: rgb(24, 24, 24);">AR</font><font style="color: rgb(66, 66, 66);">T</font><font style="color: rgb(24, 24, 24);">ICLE V</font><font style="color: rgb(66, 66, 66);">.</font></div>
      <div style="text-align: center; color: rgb(24, 24, 24);">MISCELLANEOUS</div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(40, 40, 40);">5.1</font>&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(66, 66, 66);"><u>Termination</u>. </font><font style="color: rgb(40, 40, 40);">This Agreement may </font><font style="color: rgb(24, 24, 24);">be terminated </font><font style="color: rgb(40, 40, 40);">by any Purchaser, as to such Purchaser's obligations hereunder only and without any effect whatsoever on </font><font style="color: rgb(24, 24, 24);">the
        </font><font style="color: rgb(40, 40, 40);">obligations between the Company </font><font style="color: rgb(24, 24, 24);">and </font><font style="color: rgb(40, 40, 40);">the other Purchasers, by written </font><font style="color: rgb(66, 66, 66);">notice </font><font style="color: rgb(40, 40, 40);">to the other </font><font style="color: rgb(24, 24, 24);">parties</font><font style="color: rgb(66, 66, 66);">, </font><font style="color: rgb(40, 40, 40);">if</font><font style="font-weight: bold; color: rgb(40, 40, 40);">&#160;</font><font style="color: rgb(24, 24, 24);">the </font><font style="color: rgb(40, 40, 40);">Closing has </font><font style="color: rgb(24, 24, 24);">not been consummated on or before </font><font style="color: rgb(40, 40, 40);">the fifth (5</font><sup style="color: rgb(66, 66, 66); vertical-align: text-top; line-height: 1; font-size: smaller;">th</sup><font style="color: rgb(40, 40, 40);">) </font><font style="color: rgb(24, 24, 24);">Trading




          Day following the </font><font style="color: rgb(40, 40, 40);">date hereof; </font><font style="color: rgb(38, 38, 38);"><u>provided</u>, </font><font style="color: rgb(19, 19, 19);"><u>however</u>, </font><font style="color: rgb(38, 38, 38);">that no such termination will affect the right of any party to sue for any breach by any </font><font style="color: rgb(19, 19, 19);">other party </font><font style="color: rgb(38, 38, 38);">(or </font><font style="color: rgb(19, 19, 19);">parties).</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">5.2</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(38, 38, 38);"><u>Fees and </u></font><font style="color: rgb(19, 19, 19);"><u>Expenses</u></font><font style="color: rgb(73, 73, 73);">. </font><font style="color: rgb(38, 38, 38);">Except as expressly </font><font style="color: rgb(19, 19, 19);">set forth in the </font><font style="color: rgb(38, 38, 38);">Transaction Documents to </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(38, 38, 38);">contrary, each party shall pay the </font><font style="color: rgb(19, 19, 19);">fees </font><font style="color: rgb(38, 38, 38);">and expenses of </font><font style="color: rgb(19, 19, 19);">its </font><font style="color: rgb(38, 38, 38);">advisers, </font><font style="color: rgb(19, 19, 19);">counsel, accountants </font><font style="color: rgb(38, 38, 38);">and other </font><font style="color: rgb(19, 19, 19);">experts, </font><font style="color: rgb(38, 38, 38);">if any, and all </font><font style="color: rgb(19, 19, 19);">other </font><font style="color: rgb(38, 38, 38);">expenses </font><font style="color: rgb(19, 19, 19);">incurred





        </font><font style="color: rgb(38, 38, 38);">by such party </font><font style="color: rgb(56, 56, 56);">incident </font><font style="color: rgb(38, 38, 38);">to the negotiation, preparation, execution, </font><font style="color: rgb(19, 19, 19);">delivery </font><font style="color: rgb(38, 38, 38);">and performance of </font><font style="color: rgb(19, 19, 19);">this Agreement. The Company </font><font style="color: rgb(38, 38, 38);">shall </font><font style="color: rgb(19, 19, 19);">pay </font><font style="color: rgb(38, 38, 38);">all Transfer Agent </font><font style="color: rgb(19, 19, 19);">fees</font><font style="color: rgb(38, 38, 38);"> (including, without limitation, any fees required for same-day processing
          of any instruction letter delivered by the Company), stamp taxes and other taxes and duties levied in connection with </font><font style="color: rgb(19, 19, 19);">the delivery </font><font style="color: rgb(38, 38, 38);">of any </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(38, 38, 38);"> to </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Purchasers.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">5.3</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(38, 38, 38);"><u>Entire </u></font><font style="color: rgb(19, 19, 19);"><u>Agreement</u>. </font><font style="color: rgb(38, 38, 38);">The Transaction Documents, </font><font style="color: rgb(19, 19, 19);">together </font><font style="color: rgb(38, 38, 38);">with </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">exhibits and schedules </font><font style="color: rgb(19, 19, 19);">thereto</font><font style="color: rgb(73, 73, 73);">, </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">Prospectus





          and the </font><font style="color: rgb(56, 56, 56);">Prospectus </font><font style="color: rgb(38, 38, 38);">Supplement, contain the entire understanding of the parties with respect to </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(38, 38, 38);">subject matter hereof and thereof and supersede all prior agreements and </font><font style="color: rgb(19, 19, 19);">understandings, oral </font><font style="color: rgb(38, 38, 38);">or written, with respect to
          such matters, which </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">parties acknowledge </font><font style="color: rgb(19, 19, 19);">have </font><font style="color: rgb(38, 38, 38);">been merged
          into such </font><font style="color: rgb(19, 19, 19);">documents, </font><font style="color: rgb(38, 38, 38);">exhibits and schedules.</font></div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">5.4</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(38, 38, 38);"><u>Notices</u>. </font><font style="color: rgb(19, 19, 19);">Any </font><font style="color: rgb(38, 38, 38);">and all </font><font style="color: rgb(56, 56, 56);">notices </font><font style="color: rgb(38, 38, 38);">or other communications or deliveries required or permitted to be provided hereunder shall be </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">writing and shall be deemed given and effective </font><font style="color: rgb(19, 19, 19);">on </font><font style="color: rgb(38, 38, 38);">the earliest </font><font style="color: rgb(19, 19, 19);">of: </font><font style="color: rgb(38, 38, 38);">(a) the </font><font style="color: rgb(19, 19, 19);">time </font><font style="color: rgb(38, 38, 38);">of </font><font style="color: rgb(19, 19, 19);">transmission</font><font style="color: rgb(73, 73, 73);">, </font><font style="color: rgb(19, 19, 19);">if </font><font style="color: rgb(38, 38, 38);">such notice </font><font style="color: rgb(19, 19, 19);">or </font><font style="color: rgb(38, 38, 38);">communication





        </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">delivered via email at the email address as set </font><font style="color: rgb(19, 19, 19);">forth </font><font style="color: rgb(38, 38, 38);">on the
          signature pages attached </font><font style="color: rgb(19, 19, 19);">hereto </font><font style="color: rgb(38, 38, 38);">at or </font><font style="color: rgb(19, 19, 19);">prior </font><font style="color: rgb(38, 38, 38);">to 5</font><font style="color: rgb(89, 89, 89);">:</font><font style="color: rgb(38, 38, 38);">30 p.m. (New York City </font><font style="color: rgb(19, 19, 19);">time) </font><font style="color: rgb(38, 38, 38);">on </font><font style="color: rgb(56, 56, 56);">a </font><font style="color: rgb(38, 38, 38);">Trading Day, (b) </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">next Trading </font><font style="color: rgb(19, 19, 19);">Day </font><font style="color: rgb(38, 38, 38);">after the time of transmission, </font><font style="color: rgb(73, 73, 73);">if </font><font style="color: rgb(38, 38, 38);">such notice or communication is delivered via email at the </font><font style="color: rgb(19, 19, 19);">email </font><font style="color: rgb(38, 38, 38);">address as set forth on the </font><font style="color: rgb(19, 19, 19);">signature </font><font style="color: rgb(38, 38, 38);">pages attached hereto on a day that </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">not a Trading Day or </font><font style="color: rgb(19, 19, 19);">later </font><font style="color: rgb(56, 56, 56);">than </font><font style="color: rgb(19, 19, 19);">5</font><font style="color: rgb(73, 73, 73);">:</font><font style="color: rgb(38, 38, 38);">30 p.m. (New York </font><font style="color: rgb(19, 19, 19);">City </font><font style="color: rgb(38, 38, 38);">time) on any Trading Day</font><font style="color: rgb(89, 89, 89);">,</font><font style="color: rgb(38, 38, 38);">(c) </font><font style="color: rgb(19, 19, 19);">the </font><font style="color: rgb(38, 38, 38);">second (2</font><sup style="color: rgb(38, 38, 38); vertical-align: text-top; line-height: 1; font-size: smaller;">nd</sup><font style="color: rgb(38, 38, 38);">) Trading </font><font style="color: rgb(19, 19, 19);">Day following </font><font style="color: rgb(38, 38, 38);">the </font><font style="color: rgb(19, 19, 19);">date </font><font style="color: rgb(38, 38, 38);">of mailing, </font><font style="color: rgb(19, 19, 19);">if </font><font style="color: rgb(38, 38, 38);">sent by U</font><font style="color: rgb(89, 89, 89);">.</font><font style="color: rgb(38, 38, 38);">S</font><font style="color: rgb(73, 73, 73);">. </font><font style="color: rgb(38, 38, 38);">nationally recognized overnight courier service or (d) upon actual receipt by the party to whom such notice </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">required </font><font style="color: rgb(56, 56, 56);">to </font><font style="color: rgb(38, 38, 38);">be given. The address for such </font><font style="color: rgb(19, 19, 19);">notices </font><font style="color: rgb(38, 38, 38);">and communications shall be as set forth </font><font style="color: rgb(19, 19, 19);">on </font><font style="color: rgb(38, 38, 38);">the signature pages attached hereto.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">5.5</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(19, 19, 19);"><u>Amendments; </u></font><font style="color: rgb(38, 38, 38);"><u>Waivers</u>. No provision of this
        </font><font style="color: rgb(19, 19, 19);">Agreement </font><font style="color: rgb(38, 38, 38);">may be waived, modified, supplemented or amended except in a written </font><font style="color: rgb(19, 19, 19);">instrument </font><font style="color: rgb(38, 38, 38);">signed </font><font style="color: rgb(56, 56, 56);">by the </font><font style="color: rgb(19, 19, 19);">Company </font><font style="color: rgb(38, 38, 38);">and </font><font style="color: rgb(19, 19, 19);">Purchasers





        </font><font style="color: rgb(38, 38, 38);">which purchased (or, prior to the Closing, which have agreed to purchase) at least </font><font style="color: rgb(19, 19, 19);">50.1</font><font style="color: rgb(38, 38, 38);">% in interest of the </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(38, 38, 38);">&#160;</font><font style="color: rgb(19, 19, 19);">based </font><font style="color: rgb(38, 38, 38);">on the </font><font style="color: rgb(19, 19, 19);">initial
        </font><font style="color: rgb(38, 38, 38);">Subscription Amounts hereunder; <u>provided</u>, <u>however</u>, that any provision of this Agreement may be waived by a written instrument signed by the party against whom enforcement of any such
          waived provision </font><font style="color: rgb(19, 19, 19);">is </font><font style="color: rgb(38, 38, 38);">sought</font><font style="color: rgb(89, 89, 89);">, </font><font style="color: rgb(38, 38, 38);"><u>provided</u>, <u>further</u>&#160;</font><font style="color: rgb(19, 19, 19);">that </font><font style="color: rgb(38, 38, 38);">if any amendment</font><font style="color: rgb(89, 89, 89);">, </font><font style="color: rgb(38, 38, 38);">modification or waiver disproportionately and
          adversely </font><font style="color: rgb(19, 19, 19);">impacts </font><font style="color: rgb(38, 38, 38);">a Purchaser (or group of Purchasers), </font><font style="color: rgb(56, 56, 56);">the </font><font style="color: rgb(38, 38, 38);">consent





          of such disproportionately </font><font style="color: rgb(19, 19, 19);">impacted </font><font style="color: rgb(38, 38, 38);">Purchaser (or group of Purchasers) shall also </font><font style="color: rgb(19, 19, 19);">be required. </font><font style="color: rgb(38, 38, 38);">No </font><font style="color: rgb(56, 56, 56);">delay </font><font style="color: rgb(19, 19, 19);">or </font><font style="color: rgb(38, 38, 38);">omission of any party to exercise any right hereunder shall </font><font style="color: rgb(56, 56, 56);">in </font><font style="color: rgb(38, 38, 38);">any </font><font style="color: rgb(56, 56, 56);">manner </font><font style="color: rgb(19, 19, 19);">impair </font><font style="color: rgb(38, 38, 38);">the
          exercise of any such right. </font><font style="color: rgb(19, 19, 19);">Any </font><font style="color: rgb(38, 38, 38);">amendment effected </font><font style="color: rgb(19, 19, 19);">in </font><font style="color: rgb(38, 38, 38);">accordance





          with this Section 5.5 shall be binding upon each Purchaser and holder of </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(38, 38, 38);"> and the Company.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">5.6</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Headings</u>. The headings herein </font><font style="color: rgb(52, 52, 52);">are </font><font style="color: rgb(36, 36, 36);">for convenience only, do not constitute a part of this Agreement and shall not be </font><font style="color: rgb(15, 15, 15);">deemed </font><font style="color: rgb(36, 36, 36);">to </font><font style="color: rgb(15, 15, 15);">limit </font><font style="color: rgb(36, 36, 36);">or affect any of the provisions hereof.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">5.7</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Successors and </u></font><font style="color: rgb(15, 15, 15);"><u>Assigns</u></font><font style="color: rgb(68, 68, 68);">. </font><font style="color: rgb(36, 36, 36);">This </font><font style="color: rgb(15, 15, 15);">Agreement </font><font style="color: rgb(36, 36, 36);">shall be binding upon and </font><font style="color: rgb(15, 15, 15);">inure </font><font style="color: rgb(36, 36, 36);">to the benefit </font><font style="color: rgb(15, 15, 15);">of </font><font style="color: rgb(36, 36, 36);">the parties and their successors and permitted assigns. The
          Company may not assign </font><font style="color: rgb(52, 52, 52);">this </font><font style="color: rgb(36, 36, 36);">Agreement or any rights or obligations hereunder without the prior written </font><font style="color: rgb(15, 15, 15);">consent





        </font><font style="color: rgb(36, 36, 36);">of each </font><font style="color: rgb(15, 15, 15);">Purchaser </font><font style="color: rgb(36, 36, 36);">(other </font><font style="color: rgb(15, 15, 15);">than </font><font style="color: rgb(36, 36, 36);">by merger). Any </font><font style="color: rgb(15, 15, 15);">Purchaser </font><font style="color: rgb(36, 36, 36);">may assign any or all of its rights under this Agreement </font><font style="color: rgb(15, 15, 15);">to </font><font style="color: rgb(36, 36, 36);">any </font><font style="color: rgb(15, 15, 15);">Person </font><font style="color: rgb(36, 36, 36);">to whom such Purchaser assigns or transfers </font><font style="color: rgb(52, 52, 52);">any </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(36, 36, 36);">, provided that such transferee agrees in writing to be bound, with respect to the </font><font style="color: rgb(68, 68, 68);">transferred </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(36, 36, 36);">, by the provisions of </font><font style="color: rgb(15, 15, 15);">the </font><font style="color: rgb(36, 36, 36);">Transaction Documents that apply to the
        </font><font style="color: rgb(68, 68, 68);">&#8220;P</font><font style="color: rgb(15, 15, 15);">urchaser</font><font style="color: rgb(52, 52, 52);">s.&#8221;</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">5.8</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>No </u></font><font style="color: rgb(15, 15, 15);"><u>Third-Party Beneficiaries</u>. </font><font style="color: rgb(36, 36, 36);">This </font><font style="color: rgb(15, 15, 15);">Agreement is intended </font><font style="color: rgb(36, 36, 36);">for </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(36, 36, 36);">benefit of the parties </font><font style="color: rgb(15, 15, 15);">hereto </font><font style="color: rgb(36, 36, 36);">and their </font><font style="color: rgb(52, 52, 52);">respective </font><font style="color: rgb(36, 36, 36);">successors





          and permitted assigns and </font><font style="color: rgb(52, 52, 52);">is </font><font style="color: rgb(36, 36, 36);">not for </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(36, 36, 36);">benefit of, nor may
          any provision hereof be enforced </font><font style="color: rgb(15, 15, 15);">by</font><font style="color: rgb(68, 68, 68);">, </font><font style="color: rgb(52, 52, 52);">any </font><font style="color: rgb(36, 36, 36);">other </font><font style="color: rgb(15, 15, 15);">Person</font><font style="color: rgb(68, 68, 68);">, </font><font style="color: rgb(36, 36, 36);">except as otherwise set forth in this Section 5.8.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">5.9</font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Governing </u></font><font style="color: rgb(15, 15, 15);"><u>Law</u>. All</font><font style="font-weight: bold; color: rgb(15, 15, 15);">&#160;</font><font style="color: rgb(36, 36, 36);">questions concerning the construction, validity, enforcement and interpretation </font><font style="color: rgb(15, 15, 15);">of </font><font style="color: rgb(36, 36, 36);">the Transaction </font><font style="color: rgb(15, 15, 15);">Docume</font><font style="color: rgb(68, 68, 68);">n</font><font style="color: rgb(36, 36, 36);">ts shall be governed by </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(36, 36, 36);">construed and enforced </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">accordance with the internal </font><font style="color: rgb(15, 15, 15);">laws </font><font style="color: rgb(36, 36, 36);">of the State of Delaware</font><font style="color: rgb(98, 98, 98);">, </font><font style="color: rgb(36, 36, 36);">without regard to the principles of conflicts of law </font><font style="color: rgb(52, 52, 52);">thereof</font><font style="color: rgb(121, 121, 121);">. </font><font style="color: rgb(36, 36, 36);">Each party agrees that all </font><font style="color: rgb(15, 15, 15);">legal </font><font style="color: rgb(36, 36, 36);">Proceedings concerning the </font><font style="color: rgb(15, 15, 15);">interpretations, </font><font style="color: rgb(36, 36, 36);">enforcement and defense of the transactions contemplated by </font><font style="color: rgb(52, 52, 52);">this </font><font style="color: rgb(15, 15, 15);">Ag</font><font style="color: rgb(68, 68, 68);">r</font><font style="color: rgb(36, 36, 36);">eement </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(36, 36, 36);">any other </font><font style="color: rgb(15, 15, 15);">Transac</font><font style="color: rgb(68, 68, 68);">t</font><font style="color: rgb(15, 15, 15);">ion </font><font style="color: rgb(36, 36, 36);">Documents (whether
          brought against a party hereto or </font><font style="color: rgb(15, 15, 15);">its </font><font style="color: rgb(36, 36, 36);">respective affiliates, directors, officers, shareholders, partners, members, employees or agents) shall be commenced
          exclusively </font>in the Court of Chancery of the State of Delaware, provided that if subject matter jurisdiction over the matter that is the subject of the legal proceeding is vested exclusively in the U.S. federal courts, such legal
        proceeding shall be heard in the U.S. District Court for the District of Delaware <font style="color: rgb(36, 36, 36);">for the adjudication of any dispute </font><font style="color: rgb(52, 52, 52);">hereunder </font><font style="color: rgb(36, 36, 36);">or </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">connection </font><font style="color: rgb(52, 52, 52);">herewith </font><font style="color: rgb(36, 36, 36);">or with any </font><font style="color: rgb(15, 15, 15);">transaction contemplated </font><font style="color: rgb(36, 36, 36);">hereby </font><font style="color: rgb(15, 15, 15);">or </font><font style="color: rgb(36, 36, 36);">discussed herein (including with </font><font style="color: rgb(15, 15, 15);">respect </font><font style="color: rgb(36, 36, 36);">to the enforcement </font><font style="color: rgb(15, 15, 15);">of </font><font style="color: rgb(36, 36, 36);">any of the Transaction Documents), and hereby
          irrevocably waives, and agrees not </font><font style="color: rgb(15, 15, 15);">to </font><font style="color: rgb(36, 36, 36);">assert </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">any
          Proceeding, any claim that </font><font style="color: rgb(15, 15, 15);">it is </font><font style="color: rgb(36, 36, 36);">not personally subject to </font><font style="color: rgb(52, 52, 52);">the jurisdiction </font><font style="color: rgb(36, 36, 36);">of any such </font><font style="color: rgb(52, 52, 52);">court, </font><font style="color: rgb(36, 36, 36);">that such </font><font style="color: rgb(52, 52, 52);">Proceeding </font><font style="color: rgb(15, 15, 15);">is
          improper </font><font style="color: rgb(36, 36, 36);">or is an </font><font style="color: rgb(15, 15, 15);">inconvenient </font><font style="color: rgb(36, 36, 36);">venue for such Proceeding. Each party </font><font style="color: rgb(52, 52, 52);">hereby </font><font style="color: rgb(15, 15, 15);">irrevocably </font><font style="color: rgb(36, 36, 36);">waives personal service of process </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(36, 36, 36);">consents to process being served in any such Proceeding by mailing a copy thereof via </font><font style="color: rgb(52, 52, 52);">registered </font><font style="color: rgb(36, 36, 36);">or certified mail </font><font style="color: rgb(15, 15, 15);">or </font><font style="color: rgb(36, 36, 36);">overnight delivery (with evidence of </font><font style="color: rgb(15, 15, 15);">delivery) </font><font style="color: rgb(36, 36, 36);">to such party at the address in effect
          for notices </font><font style="color: rgb(52, 52, 52);">to </font><font style="color: rgb(15, 15, 15);">it </font><font style="color: rgb(36, 36, 36);">under this </font><font style="color: rgb(15, 15, 15);">Agreement </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(36, 36, 36);">agrees that such service shall constitute good and </font><font style="color: rgb(52, 52, 52);">sufficient </font><font style="color: rgb(36, 36, 36);">service of
          process and </font><font style="color: rgb(15, 15, 15);">notice </font><font style="color: rgb(36, 36, 36);">thereof. Nothing contained herein shall be deemed to </font><font style="color: rgb(15, 15, 15);">limit</font><font style="font-weight: bold; color: rgb(15, 15, 15);">&#160;</font><font style="color: rgb(36, 36, 36);">in any way any right to serve process </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">any other manner
          permitted </font><font style="color: rgb(52, 52, 52);">by </font><font style="color: rgb(15, 15, 15);">law.</font></div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">5.10</font>&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Survival</u>. The </font><font style="color: rgb(15, 15, 15);">representations </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(36, 36, 36);">warranties contained herein </font><font style="color: rgb(52, 52, 52);">shall </font><font style="color: rgb(36, 36, 36);">survive the Closing and the delivery
          of the </font><font style="color: rgb(19, 19, 19);">Securities</font><font style="color: rgb(36, 36, 36);"> for one year </font><font style="color: rgb(52, 52, 52);">following </font><font style="color: rgb(36, 36, 36);">the Closing Date.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">5.11</font>&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(35, 35, 35);"><u>Execution</u></font><font style="color: rgb(149, 149, 149);">. </font><font style="color: rgb(35, 35, 35);">This Agreement may be executed in two </font><font style="color: rgb(52, 52, 52);">or </font><font style="color: rgb(35, 35, 35);">more </font><font style="color: rgb(52, 52, 52);">counterparts, </font><font style="color: rgb(35, 35, 35);">all of which when taken together shall be considered one and the </font><font style="color: rgb(52, 52, 52);">same </font><font style="color: rgb(35, 35, 35);">agreement and shall become effective when counterparts have been signed by
          each party and delivered to each </font><font style="color: rgb(12, 12, 12);">other </font><font style="color: rgb(35, 35, 35);">pa</font><font style="color: rgb(68, 68, 68);">r</font><font style="color: rgb(35, 35, 35);">ty</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(12, 12, 12);">it </font><font style="color: rgb(35, 35, 35);">being understood </font><font style="color: rgb(12, 12, 12);">that </font><font style="color: rgb(35, 35, 35);">the
          parties need not sign the same counterpart. </font><font style="color: rgb(12, 12, 12);">In </font><font style="color: rgb(35, 35, 35);">the event that any signature is delivered by facsimile transmission or by e-mail </font><font style="color: rgb(52, 52, 52);">delivery of a </font><font style="color: rgb(68, 68, 68);">&#8220;.pdf' </font><font style="color: rgb(35, 35, 35);">format data </font><font style="color: rgb(52, 52, 52);">file </font><font style="color: rgb(35, 35, 35);">or any electronic signature complying with the U.S. federal ESIGN </font><font style="color: rgb(12, 12, 12);">Act </font><font style="color: rgb(35, 35, 35);">of 2000, </font><font style="color: rgb(52, 52, 52);">the </font><font style="color: rgb(12, 12, 12);">Uniform </font><font style="color: rgb(35, 35, 35);">Electronic </font><font style="color: rgb(12, 12, 12);">Transactions </font><font style="color: rgb(35, 35, 35);">Act or other applicable law (e.g.,
          www.docusign.com)</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(35, 35, 35);">such signature </font><font style="color: rgb(52, 52, 52);">shall </font><font style="color: rgb(35, 35, 35);">create a valid and
          binding obl</font><font style="color: rgb(12, 12, 12);">igation </font><font style="color: rgb(35, 35, 35);">of the party executing (or on whose behalf such signature </font><font style="color: rgb(12, 12, 12);">is </font><font style="color: rgb(35, 35, 35);">executed) with the same </font><font style="color: rgb(12, 12, 12);">force </font><font style="color: rgb(35, 35, 35);">and effect as </font><font style="color: rgb(68, 68, 68);">i</font><font style="color: rgb(12, 12, 12);">f
        </font><font style="color: rgb(35, 35, 35);">such </font><font style="color: rgb(12, 12, 12);">facsimile</font><font style="color: rgb(68, 68, 68);">, </font><font style="color: rgb(52, 52, 52);">&#8220;.pdf' or </font><font style="color: rgb(86, 86, 86);">&#8220;electronic&#8221; </font><font style="color: rgb(35, 35, 35);">signature page were an original thereof.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">5.12</font>&#160;&#160;&#160;&#160;&#160;&#160; <font style="color: rgb(35, 35, 35);"><u>Severability</u>. </font><font style="color: rgb(12, 12, 12);">If </font><font style="color: rgb(35, 35, 35);">any </font><font style="color: rgb(12, 12, 12);">term</font><font style="color: rgb(68, 68, 68);">, </font><font style="color: rgb(52, 52, 52);">provision, </font><font style="color: rgb(35, 35, 35);">covenant or restriction
          of this Agreement is </font><font style="color: rgb(12, 12, 12);">held </font><font style="color: rgb(35, 35, 35);">by a court of competent </font><font style="color: rgb(52, 52, 52);">jurisdiction </font><font style="color: rgb(35, 35, 35);">to





          be invalid</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(35, 35, 35);">illegal. void or unenforceable</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(35, 35, 35);">the remainder of the
        </font><font style="color: rgb(68, 68, 68);">terms, </font><font style="color: rgb(35, 35, 35);">provisions, covenants </font><font style="color: rgb(52, 52, 52);">and restrictions set </font><font style="color: rgb(12, 12, 12);">forth </font><font style="color: rgb(35, 35, 35);">herein shall remain </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(35, 35, 35);">full force and </font><font style="color: rgb(52, 52, 52);">effect </font><font style="color: rgb(35, 35, 35);">and shall </font><font style="color: rgb(12, 12, 12);">in </font><font style="color: rgb(35, 35, 35);">no way be affected, </font><font style="color: rgb(12, 12, 12);">impaired </font><font style="color: rgb(35, 35, 35);">or
        </font><font style="color: rgb(12, 12, 12);">inv</font><font style="color: rgb(52, 52, 52);">alidated</font><font style="color: rgb(105, 105, 105);">, </font><font style="color: rgb(35, 35, 35);">and </font><font style="color: rgb(52, 52, 52);">the





        </font><font style="color: rgb(35, 35, 35);">parties hereto shall use their commercially </font><font style="color: rgb(52, 52, 52);">reasonable </font><font style="color: rgb(35, 35, 35);">efforts to find and employ an alternative means to
          achieve the same or substantially the same result as </font><font style="color: rgb(12, 12, 12);">that </font><font style="color: rgb(35, 35, 35);">contemplated by such term</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(35, 35, 35);">provision</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(35, 35, 35);">covenant or restriction</font><font style="color: rgb(86, 86, 86);">. </font><font style="color: rgb(35, 35, 35);">It is </font><font style="color: rgb(52, 52, 52);">hereby </font><font style="color: rgb(35, 35, 35);">stipulated and declared to be the </font><font style="color: rgb(52, 52, 52);">intention </font><font style="color: rgb(35, 35, 35);">of





          the parties that they would have </font><font style="color: rgb(52, 52, 52);">executed the </font><font style="color: rgb(35, 35, 35);">remaining terms, provisions, covenants and restrictions without </font><font style="color: rgb(52, 52, 52);">including </font><font style="color: rgb(35, 35, 35);">any of such that may be hereafter declared </font><font style="color: rgb(12, 12, 12);">invalid</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(35, 35, 35);">illegal</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(35, 35, 35);">void or unenforceable.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(35, 35, 35);">5.13</font>&#160;&#160;&#160;&#160; <font style="color: rgb(35, 35, 35);"><u>Remedies</u>. </font><font style="color: rgb(12, 12, 12);">In </font><font style="color: rgb(35, 35, 35);">addition to being entitled to exercise all rights </font><font style="color: rgb(12, 12, 12);">provided </font><font style="color: rgb(35, 35, 35);">herein or granted </font><font style="color: rgb(52, 52, 52);">by </font><font style="color: rgb(12, 12, 12);">law</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(12, 12, 12);">including </font><font style="color: rgb(35, 35, 35);">recovery of damages</font><font style="color: rgb(86, 86, 86);">, </font><font style="color: rgb(52, 52, 52);">each </font><font style="color: rgb(35, 35, 35);">of the Purchasers </font><font style="color: rgb(52, 52, 52);">and </font><font style="color: rgb(35, 35, 35);">the Company will be
          entitled to specific performance unde</font><font style="color: rgb(86, 86, 86);">r </font><font style="color: rgb(35, 35, 35);">the Transaction </font><font style="color: rgb(12, 12, 12);">Documen</font><font style="color: rgb(52, 52, 52);">ts</font><font style="color: rgb(86, 86, 86);">. </font><font style="color: rgb(35, 35, 35);">The parties agree </font><font style="color: rgb(52, 52, 52);">that </font><font style="color: rgb(35, 35, 35);">monetary damages </font><font style="color: rgb(52, 52, 52);">may </font><font style="color: rgb(35, 35, 35);">not be adequate compensation for any loss </font><font style="color: rgb(12, 12, 12);">incurred </font><font style="color: rgb(52, 52, 52);">by </font><font style="color: rgb(35, 35, 35);">reason of any breach of obligations contained </font><font style="color: rgb(12, 12, 12);">i</font><font style="color: rgb(68, 68, 68);">n </font><font style="color: rgb(35, 35, 35);">the Transaction Documents and </font><font style="color: rgb(52, 52, 52);">hereby </font><font style="color: rgb(35, 35, 35);">agree </font><font style="color: rgb(86, 86, 86);">t</font><font style="color: rgb(35, 35, 35);">o waive and not </font><font style="color: rgb(52, 52, 52);">to





          assert in any </font><font style="color: rgb(12, 12, 12);">Proceeding </font><font style="color: rgb(35, 35, 35);">for </font><font style="color: rgb(52, 52, 52);">specific </font><font style="color: rgb(35, 35, 35);">performance of any such
          obligation the defense </font><font style="color: rgb(52, 52, 52);">that </font><font style="color: rgb(35, 35, 35);">a remedy at </font><font style="color: rgb(12, 12, 12);">law </font><font style="color: rgb(35, 35, 35);">would be adequate.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">5.14</font>&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Independent Nature of Purchasers&#8217; </u></font><font style="color: rgb(15, 15, 15);"><u>Obligations </u></font><font style="color: rgb(36, 36, 36);"><u>and Rights</u></font><font style="color: rgb(100, 100, 100);">. </font><font style="color: rgb(36, 36, 36);">The obligations of each Purchaser under any Transaction Document are several and not </font><font style="color: rgb(15, 15, 15);">joint </font><font style="color: rgb(36, 36, 36);">with the obligations of any other Purchaser</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(36, 36, 36);">and no Purchaser shall be
          responsible in any way for the performance or non-performance of the obligations of any other Purchaser under any Transac</font><font style="color: rgb(84, 84, 84);">t</font><font style="color: rgb(36, 36, 36);">ion Document. Nothing contained </font><font style="color: rgb(61, 61, 61);">here</font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">or </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">any other
          Transaction Document, and no action taken by any Purchaser pursuant hereto or thereto</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(36, 36, 36);">shall be deemed to constitute the Purchasers as a partnership</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(36, 36, 36);">an association, a joint venture or any other </font><font style="color: rgb(15, 15, 15);">kind </font><font style="color: rgb(36, 36, 36);">of entity, or create a
          presumption that the Purchasers are in any way acting in concert </font><font style="color: rgb(15, 15, 15);">or </font><font style="color: rgb(36, 36, 36);">as a group with </font><font style="color: rgb(15, 15, 15);">respect </font><font style="color: rgb(36, 36, 36);">to such obligations or the transactions contemplated by the Transaction Documents</font><font style="color: rgb(84, 84, 84);">. </font><font style="color: rgb(36, 36, 36);">Each Purchaser shall be entitled to
          independently protect and enforce its rights including, without </font><font style="color: rgb(61, 61, 61);">lim</font><font style="color: rgb(15, 15, 15);">itation, </font><font style="color: rgb(36, 36, 36);">the rights arising out of this </font><font style="color: rgb(15, 15, 15);">Agreement </font><font style="color: rgb(36, 36, 36);">or out of the other Transaction Documents</font><font style="color: rgb(100, 100, 100);">, </font><font style="color: rgb(36, 36, 36);">and </font><font style="color: rgb(15, 15, 15);">it </font><font style="color: rgb(36, 36, 36);">shall not be necessary for any other Purchaser to be </font><font style="color: rgb(15, 15, 15);">joined </font><font style="color: rgb(36, 36, 36);">as an
          additional party </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">any </font><font style="color: rgb(15, 15, 15);">Proceeding </font><font style="color: rgb(36, 36, 36);">for such purpose. Each </font><font style="color: rgb(15, 15, 15);">Purchaser </font><font style="color: rgb(36, 36, 36);">has been represented by </font><font style="color: rgb(15, 15, 15);">its </font><font style="color: rgb(36, 36, 36);">own separate legal counsel </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">its review and negotiation of </font><font style="color: rgb(61, 61, 61);">the </font><font style="color: rgb(36, 36, 36);">Transaction Documents. </font><font style="color: rgb(15, 15, 15);">The </font><font style="color: rgb(36, 36, 36);">Company </font><font style="color: rgb(15, 15, 15);">has </font><font style="color: rgb(36, 36, 36);">elected to provide all</font><font style="color: rgb(15, 15, 15);">&#160;</font><font style="color: rgb(36, 36, 36);">Purchasers with the same terms and Transaction Documents </font><font style="color: rgb(15, 15, 15);">for </font><font style="color: rgb(36, 36, 36);">the convenience of the Company and not
          because </font><font style="color: rgb(15, 15, 15);">it </font><font style="color: rgb(36, 36, 36);">was required or requested to do so by any of the Purchasers</font><font style="color: rgb(84, 84, 84);">. </font><font style="color: rgb(15, 15, 15);">It </font><font style="color: rgb(36, 36, 36);">is expressly understood and agreed that each provision contained </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">this </font><font style="color: rgb(15, 15, 15);">Agreement </font><font style="color: rgb(36, 36, 36);">and </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">each other </font><font style="color: rgb(15, 15, 15);">Transaction





        </font><font style="color: rgb(36, 36, 36);">Document </font><font style="color: rgb(15, 15, 15);">is </font><font style="color: rgb(36, 36, 36);">between the Company and a Purchaser, solely</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(36, 36, 36);">and not between the Company and the Purchasers collectively and not between </font><font style="color: rgb(61, 61, 61);">and </font><font style="color: rgb(36, 36, 36);">among the Purchasers.</font></div>
      <div><br>
      </div>
      <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div class="BRPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">5.15</font>&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Saturdays, Sundays</u></font><font style="color: rgb(84, 84, 84);"><u>, </u></font><font style="color: rgb(36, 36, 36);"><u>Holidays, etc</u>. </font><font style="color: rgb(15, 15, 15);">If </font><font style="color: rgb(36, 36, 36);">the </font><font style="color: rgb(15, 15, 15);">last </font><font style="color: rgb(36, 36, 36);">or appointed day for the taking of any action or the expiration of any right required or granted herein shall not be a Business </font><font style="color: rgb(15, 15, 15);">D</font><font style="color: rgb(61, 61, 61);">ay, </font><font style="color: rgb(36, 36, 36);">then such action </font><font style="color: rgb(15, 15, 15);">may </font><font style="color: rgb(36, 36, 36);">be taken or such right may be exercised on the next succeeding Business Day</font><font style="color: rgb(84, 84, 84);">.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(36, 36, 36);">5.16</font>&#160;&#160;&#160;&#160; <font style="color: rgb(36, 36, 36);"><u>Construction</u>. The parties agree that each of them and/or their respective counsel have reviewed
          and had an opportunity to revise the </font><font style="color: rgb(15, 15, 15);">Transaction </font><font style="color: rgb(36, 36, 36);">Documents and</font><font style="color: rgb(84, 84, 84);">, </font><font style="color: rgb(36, 36, 36);">therefore,





        </font><font style="color: rgb(61, 61, 61);">the </font><font style="color: rgb(36, 36, 36);">normal rule of construction to the effect that any ambiguities are to be resolved against the drafting party shal</font><font style="color: rgb(15, 15, 15);">l </font><font style="color: rgb(36, 36, 36);">not be </font><font style="color: rgb(61, 61, 61);">em</font><font style="color: rgb(36, 36, 36);">ployed </font><font style="color: rgb(15, 15, 15);">in </font><font style="color: rgb(36, 36, 36);">the interpretation of the Transaction Documents or any amendments thereto. In addition, each and every </font><font style="color: rgb(61, 61, 61);">reference </font><font style="color: rgb(36, 36, 36);">to share prices and shares of
          Common Stock in any </font><font style="color: rgb(15, 15, 15);">Transaction </font><font style="color: rgb(36, 36, 36);">Document shal</font><font style="color: rgb(15, 15, 15);">l </font><font style="color: rgb(36, 36, 36);">be subject to
          adjustment for reverse and forward stock splits, stock dividends, stock combinations and other similar transactions of the Common Stock that </font><font style="color: rgb(15, 15, 15);">occur </font><font style="color: rgb(36, 36, 36);">after </font><font style="color: rgb(61, 61, 61);">the </font><font style="color: rgb(36, 36, 36);">date of this Agreement.</font></div>
      <div><br>
      </div>
      <div style="text-indent: 36pt; text-align: justify;"><font style="color: rgb(38, 38, 38);">5.17</font>&#160;&#160;&#160;&#160; <font style="color: rgb(24, 24, 24);"><u>WAIVER </u></font><font style="color: rgb(38, 38, 38);"><u>OF JURY </u></font><font style="color: rgb(24, 24, 24);"><u>TRIAL</u>. IN ANY ACTION, </font><font style="color: rgb(38, 38, 38);">SUIT, OR PROCEEDING </font><font style="color: rgb(24, 24, 24);">IN ANY JURISDICTION BROUGHT BY ANY </font><font style="color: rgb(38, 38, 38);">PARTY
        </font><font style="color: rgb(24, 24, 24);">AGAINST ANY OTHER PARTY, </font><font style="color: rgb(3, 3, 3);">THE </font><font style="color: rgb(38, 38, 38);">PARTIES EACH </font><font style="color: rgb(24, 24, 24);">KNOWINGLY AND </font><font style="color: rgb(38, 38, 38);">INTENTIONALLY, </font><font style="color: rgb(3, 3, 3);">TO THE </font><font style="color: rgb(24, 24, 24);">GREATEST </font><font style="color: rgb(38, 38, 38);">EXTENT </font><font style="color: rgb(24, 24, 24);">PERMITTED </font><font style="color: rgb(38, 38, 38);">BY APPLICABLE LAW, HEREBY </font><font style="color: rgb(24, 24, 24);">ABSOLUTELY, </font><font style="color: rgb(38, 38, 38);">UNCONDITIONALLY, </font><font style="color: rgb(24, 24, 24);">IRREVOCABLY AND </font><font style="color: rgb(38, 38, 38);">EXPRESSLY </font><font style="color: rgb(24, 24, 24);">WAIVES </font><font style="color: rgb(38, 38, 38);">FOREVER </font><font style="color: rgb(24, 24, 24);">TRIAL BY </font><font style="color: rgb(38, 38, 38);">JURY.</font></div>
      <div><br>
      </div>
      <div style="text-align: center; color: rgb(38, 38, 38);">(Signature Pages Follow)</div>
      <div style="text-align: center; color: #262626;"> <br>
      </div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
      </div>
      <div>
        <div style="text-align: justify; text-indent: 36pt;"><font style="color: rgb(15, 15, 15);">IN </font><font style="color: rgb(35, 35, 35);">WITNESS WHEREOF, the parties hereto have caused this Securities Purchase Agreement to be duly executed by
            their respective authorized signatories as of the date first </font><font style="color: rgb(15, 15, 15);">indicated </font><font style="color: rgb(35, 35, 35);">above.</font></div>
        <div><br>
        </div>
        <div style="color: #232323; font-weight: bold;">OPUS GENETICS, INC.</div>
        <div><br>
        </div>
        <div>
          <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; color: #000000; width: 100%;" id="za0327c3f2a5042a8926f627a0389c0b8">

              <tr>
                <td style="width: 3%; padding-bottom: 2px;"><font style="color: #232323;">By</font><font style="color: #545454;">:</font></td>
                <td style="width: 30%; border-bottom: 2px solid rgb(0, 0, 0);">
                  <div>/s/ George Magrath, MD <br>
                  </div>
                </td>
                <td style="width: 67%; padding-bottom: 2px;">
                  <div>&#160;</div>
                </td>
              </tr>
              <tr>
                <td rowspan="1" style="width: 3%;"><font style="color: #232323;">Name</font><font style="color: #545454;">:</font></td>
                <td rowspan="1" style="width: 30%;">George Magrath, MD </td>
                <td rowspan="1" style="width: 67%;">&#160;</td>
              </tr>
              <tr>
                <td rowspan="1" style="width: 3%;">Title:</td>
                <td rowspan="1" style="width: 30%;">Chief Executive Officer </td>
                <td rowspan="1" style="width: 67%;">&#160;</td>
              </tr>

          </table>
        </div>
      </div>
      <div>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;<font style="color: #545454;"> <br>
        </font></div>
      <div style="color: #232323;">Address for Notice:</div>
      <div><br>
      </div>
      <div style="color: #232323;">8 Davis Drive, Suite 220</div>
      <div style="color: #232323;">Durham, NC 27709</div>
      <div style="color: #232323;">Attention: Chief Executive Officer</div>
      <div style="color: #232323;">E-mail: [***]</div>
      <div><br>
      </div>
      <div><font style="color: #232323;">With a copy to </font><font style="color: #383838;">(which shall </font><font style="color: #232323;">not constitute notice):</font></div>
      <div><br>
      </div>
      <div style="text-indent: 27pt; margin-left: 9pt;"><font style="color: rgb(35, 35, 35);">Sidley Austin</font><font style="color: rgb(15, 15, 15);">&#160;</font><font style="color: rgb(35, 35, 35);">LLP</font></div>
      <div style="color: rgb(35, 35, 35); text-indent: 27pt; margin-left: 9pt;">2850 Quarry Lake Drive, Suite 301</div>
      <div style="color: rgb(35, 35, 35); text-indent: 27pt; margin-left: 9pt;">Baltimore, Maryland 21209</div>
      <div style="color: rgb(35, 35, 35); text-indent: 27pt; margin-left: 9pt;">Attention: Asher M. Rubin</div>
      <div style="color: rgb(35, 35, 35); text-indent: 27pt; margin-left: 9pt;">E-mail: arubin@sidley.com</div>
      <div><br>
      </div>
      <div>
        <div style="text-align: center;"><font style="color: #232323;">[REMAINDER OF </font><font style="color: #0F0F0F;">PAGE INTENTIONALLY LEFT </font><font style="color: #232323;">BLANK]</font></div>
        <div style="text-align: center;"><font style="color: #232323;"> <br>
          </font></div>
      </div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
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      </div>
      <div style="text-align: justify;"><font style="color: #282828;">IN </font><font style="color: #131313;">WITNESS </font><font style="color: #282828;">WHEREOF</font><font style="color: #545454;">, </font><font style="color: #131313;">the </font><font style="color: #282828;">undersigned have </font><font style="color: #131313;">caused this </font><font style="color: #282828;">Securities </font><font style="color: #131313;">Purchase </font><font style="color: #282828;">Agreement to be duly
          executed by their respective authorized signatories as of the date </font><font style="color: #131313;">first indicated </font><font style="color: #282828;">above.</font></div>
      <div><br>
      </div>
      <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z1d06aade5c6f40e6a0d21b0c856a3f7e">

          <tr>
            <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
              <div><font style="color: #282828;">Name of </font><font style="color: #131313;">Purchaser:&#160;&#160;&#160;&#160; <br>
                </font></div>
            </td>
            <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 90%;">Atlas Diversified Master Fund, Ltd. <br>
            </td>
            <td style="width: 10.22%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
          </tr>

      </table>
      <div><font style="color: #131313;"> </font><br>
      </div>
      <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zfe5ddcb31efc4fc8b91bfe18afaa9410">

          <tr>
            <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
              <div style="color: #282828;">Signature of Authorized Signatory of Purchaser:&#160;&#160;&#160; <br>
              </div>
            </td>
            <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 85%;">&#160;/s/ Mark Romis <br>
            </td>
            <td style="width: 10.22%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
          </tr>

      </table>
      <div><br>
      </div>
      <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z030aa3611dc842f892790de89c7d724d">

          <tr>
            <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
              <div style="color: #282828;">Name of Authorized Signatory:&#160;&#160;&#160; <br>
              </div>
            </td>
            <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 90%;">Mark Romis <br>
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            <td style="width: 10.22%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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            <td style="width: 33.33%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">[***] <br>
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            <td style="width: 34%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
            <td style="width: 33.34%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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          <tr>
            <td style="width: 33.33%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">&#160;</td>
            <td style="width: 34%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
            <td style="width: 33.34%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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          <tr>
            <td style="width: 33.33%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">&#160;</td>
            <td style="width: 34%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
            <td style="width: 33.34%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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          <tr>
            <td style="width: 33.33%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">&#160;</td>
            <td style="width: 34%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
            <td style="width: 33.34%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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      <div><font style="color: #282828;">Address </font><font style="color: #131313;">for Delivery of Securities</font><font style="color: #282828;"> to Purchaser </font><font style="font-weight: bold; color: #282828;">(</font><font style="color: #282828;">if</font><font style="font-weight: bold; color: #282828;">&#160;</font><font style="color: #282828;">not same as address for</font><font style="font-weight: bold; color: #282828;">&#160;</font><font style="color: #282828;">notice): [***]<br>
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          <tr>
            <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
              <div><font style="color: #282828;">Subscription </font><font style="color: #131313;">Amount:&#160;&#160;&#160; <br>
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            <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">$9,999,758.69 <br>
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            <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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          <tr>
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            <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">2,392,344 <br>
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            <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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          <tr>
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              <div style="color: #282828;">Pre-Funded Warrants:&#160;&#160;&#160; <br>
              </div>
            </td>
            <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">2,392,344 <br>
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            <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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          <tr>
            <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
              <div style="text-align: justify; color: #282828;">EIN Number:&#160;&#160;&#160; <br>
              </div>
            </td>
            <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">[***] <br>
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            <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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      <div>IN WITNESS WHEREOF, the undersigned have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first indicated above.<br>
        <br>
        <font style="font-weight: bold;">Nantahala Capital Partners Limited Partnership</font><br>
        <br>
        By: Nantahala Capital Management, LLC<br>
        Its General Partner<br>
        <br>
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            <tr>
              <td style="width: 3%; padding-bottom: 2px;">
                <div>By: <br>
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              <td style="width: 30%; border-bottom: 2px solid rgb(0, 0, 0);">
                <div>/s/ Wilmot Harkey <br>
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              <td style="width: 67%; padding-bottom: 2px;">
                <div>&#160;</div>
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            </tr>
            <tr>
              <td style="width: 3%;">
                <div>Name: <br>
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              </td>
              <td style="width: 30%;">
                <div>Wilmot Harkey <br>
                </div>
              </td>
              <td style="width: 67%;">
                <div>&#160;</div>
              </td>
            </tr>
            <tr>
              <td style="width: 3%;">
                <div>Title: <br>
                </div>
              </td>
              <td style="width: 30%;">
                <div>Manager <br>
                </div>
              </td>
              <td style="width: 67%;">
                <div>&#160;</div>
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        </table>
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      <div><font style="font-weight: bold;">Legal Entity Name and Address:</font><br>
        Nantahala Capital Partners Limited Partnership<br>
        130 Main St., 2nd Floor<br>
        New Canaan, CT 06840<br>
        <br>
        <font style="font-weight: bold;">Notifications:</font><br>
        Contact: Operations Team<br>
        Email (preferred): [***]<br>
        <br>
        Address for Delivery of Securities to Purchaser (if not same as address for notice):<br>
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        </div>
        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
                <div><font style="color: #282828;">Subscription </font><font style="color: #131313;">Amount:&#160;&#160;&#160; <br>
                  </font></div>
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              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">$1,953,529.27<br>
              </td>
              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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        </table>
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            <tr>
              <td style="vertical-align: top; padding-bottom: 2px;">
                <div style="color: #282828;">Shares:&#160;&#160;&#160; <br>
                </div>
              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">934,703<br>
              </td>
              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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        </table>
        <div><br>
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        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
                <div style="color: #282828;">Pre-Funded Warrants:&#160;&#160;&#160; <br>
                </div>
              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">0<br>
              </td>
              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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        </table>
        <div><br>
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        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
                <div style="text-align: justify; color: #282828;">EIN Number:&#160;&#160;&#160; <br>
                </div>
              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">[***] <br>
              </td>
              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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        IN WITNESS WHEREOF, the undersigned have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first indicated above.<br>
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        <font style="font-weight: bold;">BLACKWELL PARTNERS LLC - SERIES A, solely with respect to the portion of<br>
          its assets for which Nantahala Capital Management, LLC acts as its Investment<br>
          Manager<br>
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        By: Nantahala Capital Management, LLC<br>
        Its Investment Manager<br>
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          <div><br>
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                  <td style="width: 3%; padding-bottom: 2px;">
                    <div>By: <br>
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                  </td>
                  <td style="width: 30%; border-bottom: 2px solid rgb(0, 0, 0);">
                    <div>/s/ Wilmot Harkey <br>
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                  <td style="width: 67%; padding-bottom: 2px;">
                    <div>&#160;</div>
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                </tr>
                <tr>
                  <td style="width: 3%;">
                    <div>Name: <br>
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                  </td>
                  <td style="width: 30%;">
                    <div>Wilmot Harkey <br>
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                  </td>
                  <td style="width: 67%;">
                    <div>&#160;</div>
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                </tr>
                <tr>
                  <td style="width: 3%;">
                    <div>Title: <br>
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                  <td style="width: 30%;">
                    <div>Manager <br>
                    </div>
                  </td>
                  <td style="width: 67%;">
                    <div>&#160;</div>
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            </table>
          </div>
        </div>
      </div>
      <div> <br>
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      <div><font style="font-weight: bold;">Legal Entity Name and Address:</font><br>
        <font style="font-weight: bold;">BLACKWELL PARTNERS LLC - SERIES A</font><br>
        280 South Mangum Street, Suite 210<br>
        Durham, NC 27701<br>
        <br>
        <font style="font-weight: normal;">Notifications:</font><br>
        Contact: Operations Team, Janine Lall<br>
        Email (preferred): [***]<br>
        <br>
        Address for Delivery of Securities to Purchaser (if not same as address for notice):<br>
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        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
                <div><font style="color: #282828;">Subscription </font><font style="color: #131313;">Amount:&#160;&#160;&#160; <br>
                  </font></div>
              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">$1,046,471.36<br>
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              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
            </tr>

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        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td style="vertical-align: top; padding-bottom: 2px;">
                <div style="color: #282828;">Shares:&#160;&#160;&#160; <br>
                </div>
              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">500,704<br>
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              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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        </table>
        <div><br>
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        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
                <div style="color: #282828;">Pre-Funded Warrants:&#160;&#160;&#160; <br>
                </div>
              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">0<br>
              </td>
              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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        </table>
        <div><br>
        </div>
        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
                <div style="text-align: justify; color: #282828;">EIN Number:&#160;&#160;&#160; <br>
                </div>
              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">[***] <br>
              </td>
              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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        IN WITNESS WHEREOF, the undersigned have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first indicated above.<br>
        <br>
        Name of Purchaser: Perceptive Life Sciences Master Fund, Ltd.<br>
        <br>
        Signature of Authorized Signatory of Purchaser: /s/ James H. Mannix<br>
        <br>
        Name of Authorized Signatory: James H. Mannix<br>
        <br>
        Title of Authorized Signatory: COO<br>
        <br>
        Email Address of Authorized Signatory: [***]<br>
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        Address for Notice to Purchaser:<br>
        <br>
        Perceptive Advisors LLC<br>
        51 Astor Place, Floor 10<br>
        New York, NY 10003<br>
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        Address for Delivery of Securities to Purchaser (if not same as address for notice):<br>
        <br>
        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
                <div><font style="color: #282828;">Subscription </font><font style="color: #131313;">Amount:&#160;&#160;&#160; <br>
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              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">$9,999,521.54<br>
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              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
            </tr>

        </table>
        <div><br>
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                <div style="color: #282828;">Shares:&#160;&#160;&#160; <br>
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              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">0<br>
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              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;">

            <tr>
              <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
                <div style="color: #282828;">Pre-Funded Warrants:&#160;&#160;&#160; <br>
                </div>
              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">4,784,689&#160;&#160;&#160; <br>
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              <td style="width: 60%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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            <tr>
              <td nowrap="nowrap" style="vertical-align: top; padding-bottom: 2px;">
                <div style="text-align: justify; color: #282828;">EIN Number:&#160;&#160;&#160; <br>
                </div>
              </td>
              <td style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); width: 35%;">[***] <br>
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      <div style="text-align: center; font-variant: small-caps; font-weight: bold;">Exhibit A</div>
      <div><br>
      </div>
      <div style="text-align: center; font-weight: bold;">Form of Pre-Funded Warrant</div>
      <div style="text-align: center; font-weight: bold;"> <br>
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<DOCUMENT>
<TYPE>EX-101.LAB
<SEQUENCE>6
<FILENAME>ird-20251105_lab.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE
<TEXT>
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_WrittenCommunications" xlink:label="WrittenCommunications" xlink:title="WrittenCommunications" />
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SolicitingMaterial" xlink:label="SolicitingMaterial" xlink:title="SolicitingMaterial" />
    <link:label xlink:type="resource" xlink:label="dei_SolicitingMaterial" xlink:role="http://www.xbrl.org/2003/role/label" xlink:title="dei_SolicitingMaterial" xml:lang="en-US" id="dei_SolicitingMaterial">Soliciting Material</link:label>
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementTenderOffer" xlink:label="PreCommencementTenderOffer" xlink:title="PreCommencementTenderOffer" />
    <link:label xlink:type="resource" xlink:label="dei_PreCommencementTenderOffer" xlink:role="http://www.xbrl.org/2003/role/label" xlink:title="dei_PreCommencementTenderOffer" xml:lang="en-US" id="dei_PreCommencementTenderOffer">Pre-commencement Tender Offer</link:label>
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementIssuerTenderOffer" xlink:label="PreCommencementIssuerTenderOffer" xlink:title="PreCommencementIssuerTenderOffer" />
    <link:label xlink:type="resource" xlink:label="dei_PreCommencementIssuerTenderOffer" xlink:role="http://www.xbrl.org/2003/role/label" xlink:title="dei_PreCommencementIssuerTenderOffer" xml:lang="en-US" id="dei_PreCommencementIssuerTenderOffer">Pre-commencement Issuer Tender Offer</link:label>
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_AmendmentFlag" xlink:label="AmendmentFlag" xlink:title="AmendmentFlag" />
    <link:label xlink:type="resource" xlink:label="dei_AmendmentFlag" xlink:role="http://www.xbrl.org/2003/role/label" xlink:title="dei_AmendmentFlag" xml:lang="en-US" id="dei_AmendmentFlag">Amendment Flag</link:label>
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    <link:label xlink:type="resource" xlink:label="dei_DocumentFiscalYearFocus" xlink:role="http://www.xbrl.org/2003/role/label" xlink:title="dei_DocumentFiscalYearFocus" xml:lang="en-US" id="dei_DocumentFiscalYearFocus">Document Fiscal Year Focus</link:label>
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityRegistrantName" xlink:label="EntityRegistrantName" xlink:title="EntityRegistrantName" />
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityCentralIndexKey" xlink:label="EntityCentralIndexKey" xlink:title="EntityCentralIndexKey" />
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityFileNumber" xlink:label="EntityFileNumber" xlink:title="EntityFileNumber" />
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityIncorporationStateCountryCode" xlink:label="EntityIncorporationStateCountryCode" xlink:title="EntityIncorporationStateCountryCode" />
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityEmergingGrowthCompany" xlink:label="EntityEmergingGrowthCompany" xlink:title="EntityEmergingGrowthCompany" />
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressAddressLine2" xlink:label="EntityAddressAddressLine2" xlink:title="EntityAddressAddressLine2" />
    <link:label xlink:type="resource" xlink:label="dei_EntityAddressAddressLine2" xlink:role="http://www.xbrl.org/2003/role/label" xlink:title="dei_EntityAddressAddressLine2" xml:lang="en-US" id="dei_EntityAddressAddressLine2">Entity Address, Address Line Two</link:label>
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressAddressLine3" xlink:label="EntityAddressAddressLine3" xlink:title="EntityAddressAddressLine3" />
    <link:label xlink:type="resource" xlink:label="dei_EntityAddressAddressLine3" xlink:role="http://www.xbrl.org/2003/role/label" xlink:title="dei_EntityAddressAddressLine3" xml:lang="en-US" id="dei_EntityAddressAddressLine3">Entity Address, Address Line Three</link:label>
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressCityOrTown" xlink:label="EntityAddressCityOrTown" xlink:title="EntityAddressCityOrTown" />
    <link:label xlink:type="resource" xlink:label="dei_EntityAddressCityOrTown" xlink:role="http://www.xbrl.org/2003/role/label" xlink:title="dei_EntityAddressCityOrTown" xml:lang="en-US" id="dei_EntityAddressCityOrTown">Entity Address, City or Town</link:label>
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressStateOrProvince" xlink:label="EntityAddressStateOrProvince" xlink:title="EntityAddressStateOrProvince" />
    <link:label xlink:type="resource" xlink:label="dei_EntityAddressStateOrProvince" xlink:role="http://www.xbrl.org/2003/role/label" xlink:title="dei_EntityAddressStateOrProvince" xml:lang="en-US" id="dei_EntityAddressStateOrProvince">Entity Address, State or Province</link:label>
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    <link:loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressCountry" xlink:label="EntityAddressCountry" xlink:title="EntityAddressCountry" />
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<DOCUMENT>
<TYPE>EX-101.PRE
<SEQUENCE>7
<FILENAME>ird-20251105_pre.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE
<TEXT>
<XBRL>
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end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>10
<FILENAME>R1.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="include/report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
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</head>
<body>
<span style="display: none;">v3.25.3</span><table class="report" border="0" cellspacing="2" id="id2">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Document and Entity Information<br></strong></div></th>
<th class="th"><div>Nov. 05, 2025</div></th>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_CoverAbstract', window );"><strong>Cover [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentType', window );">Document Type</a></td>
<td class="text">8-K<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_AmendmentFlag', window );">Amendment Flag</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_DocumentPeriodEndDate', window );">Document Period End Date</a></td>
<td class="text">Nov.  05,  2025<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityFileNumber', window );">Entity File Number</a></td>
<td class="text">001-34079<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityRegistrantName', window );">Entity Registrant Name</a></td>
<td class="text">Opus Genetics, Inc.<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityCentralIndexKey', window );">Entity Central Index Key</a></td>
<td class="text">0001228627<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityIncorporationStateCountryCode', window );">Entity Incorporation, State or Country Code</a></td>
<td class="text">DE<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityTaxIdentificationNumber', window );">Entity Tax Identification Number</a></td>
<td class="text">11-3516358<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressAddressLine1', window );">Entity Address, Address Line One</a></td>
<td class="text">8 DAVIS DRIVE<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressAddressLine2', window );">Entity Address, Address Line Two</a></td>
<td class="text">SUITE 220<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressCityOrTown', window );">Entity Address, City or Town</a></td>
<td class="text">DURHAM<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressStateOrProvince', window );">Entity Address, State or Province</a></td>
<td class="text">NC<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityAddressPostalZipCode', window );">Entity Address, Postal Zip Code</a></td>
<td class="text">27713<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_CityAreaCode', window );">City Area Code</a></td>
<td class="text">248<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_LocalPhoneNumber', window );">Local Phone Number</a></td>
<td class="text">681-9815<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_Security12bTitle', window );">Title of 12(b) Security</a></td>
<td class="text">Common Stock, $0.0001 par value per share<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_TradingSymbol', window );">Trading Symbol</a></td>
<td class="text">IRD<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_SecurityExchangeName', window );">Security Exchange Name</a></td>
<td class="text">NASDAQ<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_EntityEmergingGrowthCompany', window );">Entity Emerging Growth Company</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_WrittenCommunications', window );">Written Communications</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_SolicitingMaterial', window );">Soliciting Material</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_PreCommencementTenderOffer', window );">Pre-commencement Tender Offer</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl" style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="Show.showAR( this, 'defref_dei_PreCommencementIssuerTenderOffer', window );">Pre-commencement Issuer Tender Offer</a></td>
<td class="text">false<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_AmendmentFlag">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_AmendmentFlag</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CityAreaCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Area code of city</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CityAreaCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CoverAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Cover page.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CoverAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentPeriodEndDate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>For the EDGAR submission types of Form 8-K: the date of the report, the date of the earliest event reported; for the EDGAR submission types of Form N-1A: the filing date; for all other submission types: the end of the reporting or transition period. The format of the date is YYYY-MM-DD.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentPeriodEndDate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:dateItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentType">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentType</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:submissionTypeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Address Line 1 such as Attn, Building Name, Street Name</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine2">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Address Line 2 such as Street or Suite number</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine2</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressCityOrTown">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Name of the City or Town</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressCityOrTown</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressPostalZipCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Code for the postal or zip code</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressPostalZipCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressStateOrProvince">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Name of the state or province.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressStateOrProvince</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:stateOrProvinceItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCentralIndexKey">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCentralIndexKey</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:centralIndexKeyItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityEmergingGrowthCompany">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Indicate if registrant meets the emerging growth company criteria.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityEmergingGrowthCompany</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityFileNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityFileNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:fileNumberItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityIncorporationStateCountryCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Two-character EDGAR code representing the state or country of incorporation.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityIncorporationStateCountryCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarStateCountryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityRegistrantName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityRegistrantName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityTaxIdentificationNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityTaxIdentificationNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:employerIdItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_LocalPhoneNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Local phone number for entity.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_LocalPhoneNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_PreCommencementIssuerTenderOffer">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 13e<br> -Subsection 4c<br></p></div>
<a href="javascript:void(0);" onclick="Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_PreCommencementIssuerTenderOffer</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
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