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Commitments and Contingencies - Additional Information (Details) $ in Thousands |  |  |  |  |  | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | --- | --- | --- | --- | ---
Dec. 23, 2022 USD ($) | Jun. 15, 2022 USD ($) | Nov. 09, 2021 USD ($) | Apr. 10, 2019 USD ($) | Jun. 06, 2018 USD ($) | Jun. 30, 2026 USD ($) obligation | Jun. 30, 2025 USD ($) | Jun. 30, 2026 USD ($) obligation | Jun. 30, 2025 USD ($) | Nov. 05, 2020 obligation
Type of Arrangement [Abstract] |  |  |  |  |  |  |  |  |  |
Payments for CVR |  |  |  |  |  | $ 0 |  | $ 0 |  |
Number of milestones accrued | obligation |  |  |  |  |  | 0 |  | 0 |  |
Number of potential milestones | obligation |  |  |  |  |  | 0 |  | 0 |  |
Rent expense |  |  |  |  |  | $ 100 | $ 100 | $ 200 | $ 200 |
Rexahn |  |  |  |  |  |  |  |  |  |
Type of Arrangement [Abstract] |  |  |  |  |  |  |  |  |  |
Number of contingent value right received per common stock | obligation |  |  |  |  |  |  |  |  |  | 1
LCA5/RDH12 Agreement | Development, Regulatory and Commercial Milestone | Maximum |  |  |  |  |  |  |  |  |  |
Type of Arrangement [Abstract] |  |  |  |  |  |  |  |  |  |
Milestone payments |  | $ 2,600 |  |  |  |  |  |  |  |
Iveric Agreement | Commercial Milestones | Maximum | BEST1 Program |  |  |  |  |  |  |  |  |  |
Type of Arrangement [Abstract] |  |  |  |  |  |  |  |  |  |
Milestone payments | $ 111,700 |  |  |  |  |  |  |  |  |
BEST1 License Agreement | Commercial Milestones | Maximum | First Licensed Product |  |  |  |  |  |  |  |  |  |
Type of Arrangement [Abstract] |  |  |  |  |  |  |  |  |  |
Milestone payments |  |  |  | $ 76,400 |  |  |  |  |  |
Penn and UF RHO License Agreement | Development, Regulatory and Commercial Milestone | Maximum |  |  |  |  |  |  |  |  |  |
Type of Arrangement [Abstract] |  |  |  |  |  |  |  |  |  |
Milestone payments |  |  |  |  | $ 93,500 |  |  |  |  |
Massachusetts Eye and Ear Infirmary License Agreement | Development, Regulatory and Commercial Milestone | Maximum |  |  |  |  |  |  |  |  |  |
Type of Arrangement [Abstract] |  |  |  |  |  |  |  |  |  |
Milestone payments |  |  | $ 400 |  |  |  |  |  |  |

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