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Stock-Based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2015
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] |
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] | Stock-based compensation expense recognized was as follows:
|  | Three Months Ended March 31, |
|  | 2015 |  | 2014 |
|  | (Unaudited) |  | (Unaudited) |
Research and development expense |  | $ | 29,000 |  | $ | 38,000 |
General and administrative expense |  |  | 23,000 |  |  | 196,000 |
Total stock-based compensation expense |  | $ | 52,000 |  | $ | 234,000 |
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] | The following table summarizes stock option activity for the three months ended March 31, 2015:
|  |  |  |  | Options Outstanding |
|  | Shares |  |  |  | Weighted Average |  | Average Remaining |  |  |
|  | Available for |  |  |  | Exercise |  | Contractual Term |  | Intrinsic |
|  | Grant |  | Shares |  | Price |  | (Years) |  | Value |
Balance, December 31, 2014 |  |  | 39,250,000 |  |  | 22,034,747 |  | $ | 0.19 |  |  | 8.18 |  | $ | 640,837 |
Granted |  |  | — |  |  | — |  |  | — |  |  | — |  |  | — |
Exercised |  |  | — |  |  | — |  |  | — |  |  | — |  |  | — |
Forfeited |  |  | — |  |  | — |  |  | — |  |  | — |  |  | — |
Expired |  |  | — |  |  | — |  |  | — |  |  | — |  |  | — |
Balance, March 31, 2015 |  |  | 39,250,000 |  |  | 22,034,747 |  | $ | 0.19 |  |  | 7.93 |  | $ | 2,561,000 |
Vested or expected to vest at March 31, 2015 |  |  |  |  |  | 21,890,939 |  | $ | 0.19 |  |  | 7.92 |  | $ | 2,547,000 |
Exercisable at March 31, 2015 |  |  |  |  |  | 19,995,058 |  | $ | 0.18 |  |  | 7.92 |  | $ | 2,396,000 |
Schedule of Common Stock, Capital Shares Reserved for Future Issuance [Table Text Block] | As of March 31, 2015, the Company had reserved shares of its common stock for future issuance as follows:
|  | Shares Reserved |
Stock options outstanding |  |  | 22,034,747 |
Available for future grants under the Stock Incentive Plan |  |  | 39,250,000 |
Warrants |  |  | 63,314,696 |
Total Shares reserved |  |  | 124,599,443 |

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- Definition Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 14.F) -URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 14 -Section F Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the number and weighted-average exercise prices (or conversion ratios) for share options (or share units) that were outstanding at the beginning and end of the year, vested and expected to vest, exercisable or convertible at the end of the year, and the number of share options or share units that were granted, exercised or converted, forfeited, and expired during the year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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