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Collaborative and Other Agreements (Narrative) (Details) - USD ($) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2015 | Sep. 30, 2015 | Jun. 30, 2015 | Mar. 31, 2015 | Dec. 31, 2014 | Sep. 30, 2014 | Jun. 30, 2014 | Mar. 31, 2014 | Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Licensing Payments Received | $ 128,000 | $ 143,000 | $ 102,000 | $ 102,000 | $ 101,000 | $ 103,000 | $ 101,000 | $ 104,000 | $ 475,000 | $ 409,000 |
Intrexon Corporation [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Value of common stock paid for technology access fee |  |  |  |  |  |  |  |  |  |  | $ 3,000,000
Fees Payable Upon Commencement Of The First Phase 2 Trial | 2,500,000 |  |  |  |  |  |  |  | 2,500,000 |  |
Fees Payable Upon First Regulatory Approval | $ 5,000,000 |  |  |  |  |  |  |  | 5,000,000 |  |
Expenses Incurred Under Channel Collaborative Agreement |  |  |  |  |  |  |  |  | 178,000 | 862,000 |
Cash Paid For Channel Collaboration Agreement |  |  |  |  |  |  |  |  | 125,000 | 941,000 |
University Of Leicester [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Expenses Under Collaborative Agreement |  |  |  |  |  |  |  |  | 265,000 | 232,000 |
Cash Paid For Collaboration Agreement |  |  |  |  |  |  |  |  | $ 290,000 | 182,000 |
Collaborative Agreement Expiration Date |  |  |  |  |  |  |  |  | Nov. 12, 2018 |  |
University Of Glasgow [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Expenses Under Collaborative Agreement |  |  |  |  |  |  |  |  | $ 61,000 | 184,000 |
Walter Reed Army Institute Of Research [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Payments For Services Under Collaborative Agreement |  |  |  |  |  |  |  |  | 0 | $ 207,000 |
Takara Bio Inc [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Licensing Payments Received |  |  |  |  |  |  |  |  | $ 40,000 |  |
Takara Bio Inc [Member] | Nonsoftware License Arrangement [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percent of License Product Sales Receivable |  |  |  |  |  |  |  |  | 12.00% |  |
Percent of License Product Service Revenues Receivable |  |  |  |  |  |  |  |  | 6.00% |  |
Minimum Annual Royalty Payments Receivable |  |  |  |  |  |  |  |  | $ 15,000 |  |
Takara Bio Inc [Member] | Nonsoftware License Arrangement [Member] | Criteria One [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent Licensing Receivable |  |  |  |  |  |  |  |  | 30,000 |  |
Licensed Product Revenues Milestone Benchmark |  |  |  |  |  |  |  |  | 1,000,000 |  |
Takara Bio Inc [Member] | Nonsoftware License Arrangement [Member] | Criteria Two [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent Licensing Receivable |  |  |  |  |  |  |  |  | 40,000 |  |
Licensed Product Net Sales Milestone Benchmark |  |  |  |  |  |  |  |  | $ 2,000,000 |  |

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