<SEC-DOCUMENT>0001140361-16-091123.txt : 20161229
<SEC-HEADER>0001140361-16-091123.hdr.sgml : 20161229
<ACCEPTANCE-DATETIME>20161229213627
ACCESSION NUMBER:		0001140361-16-091123
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20161227
FILED AS OF DATE:		20161229
DATE AS OF CHANGE:		20161229

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AmpliPhi Biosciences Corp
		CENTRAL INDEX KEY:			0000921114
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				911549568
		STATE OF INCORPORATION:			WA
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3579 VALLEY CENTRE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		804-827-2524

	MAIL ADDRESS:	
		STREET 1:		3579 VALLEY CENTRE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TARGETED GENETICS CORP /WA/
		DATE OF NAME CHANGE:	19940331

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			INTREXON CORP
		CENTRAL INDEX KEY:			0001356090
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		STATE OF INCORPORATION:			VA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37544
		FILM NUMBER:		162076220

	BUSINESS ADDRESS:	
		STREET 1:		1750 KRAFT DRIVE
		STREET 2:		SUITE 1400
		CITY:			BLACKSBURG
		STATE:			VA
		ZIP:			24060
		BUSINESS PHONE:		301-556-9809

	MAIL ADDRESS:	
		STREET 1:		1750 KRAFT DRIVE
		STREET 2:		SUITE 1400
		CITY:			BLACKSBURG
		STATE:			VA
		ZIP:			24060

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			KIRK RANDAL J
		CENTRAL INDEX KEY:			0001091823

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37544
		FILM NUMBER:		162076221

	MAIL ADDRESS:	
		STREET 1:		1881 GROVE AVENUE
		CITY:			RADFORD
		STATE:			VA
		ZIP:			24141
</SEC-HEADER>
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<SEQUENCE>1
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    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001356090</rptOwnerCik>
            <rptOwnerName>INTREXON CORP</rptOwnerName>
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        <reportingOwnerAddress>
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            <rptOwnerStreet2>20374 SENECA MEADOWS PARKWAY</rptOwnerStreet2>
            <rptOwnerCity>GERMANTOWN</rptOwnerCity>
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            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
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                    <footnoteId id="F1"/>
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                    <value>.51</value>
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                <transactionAcquiredDisposedCode>
                    <value>D</value>
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                <sharesOwnedFollowingTransaction>
                    <value>734696</value>
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                <directOrIndirectOwnership>
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        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
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    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Pursuant to a joint selling program, NRM VII Holdings I, LLC (&quot;NRM VII Holdings&quot;) and Intrexon Corporation (&quot;Intrexon&quot;) sold shares on a pro rata basis.</footnote>
        <footnote id="F2">Randal J. Kirk controls NRM VII Holdings. Shares held by this entity may be deemed to be indirectly beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.</footnote>
        <footnote id="F3">Randal J. Kirk, directly and through certain affiliates, has voting and dispositive power over a majority of the outstanding capital stock of Intrexon. Mr. Kirk may therefore be deemed to have voting and dispositive power over the shares of the issuer owned by Intrexon. Shares held by Intrexon may be deemed to be indirectly beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/  Randal J. Kirk</signatureName>
        <signatureDate>2016-12-29</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/  Randal J. Kirk, CEO of Intrexon Corporation</signatureName>
        <signatureDate>2016-12-29</signatureDate>
    </ownerSignature>
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</DOCUMENT>
</SEC-DOCUMENT>
