    <SEC-DOCUMENT>0001144204-16-103969-index.html : 20160520
    <SEC-HEADER>0001144204-16-103969.hdr.sgml : 20160520
    <ACCEPTANCE-DATETIME>20160520171118
    ACCESSION NUMBER:		0001144204-16-103969
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		6
    CONFORMED PERIOD OF REPORT:	20160620
    FILED AS OF DATE:		20160520
    DATE AS OF CHANGE:		20160520
    EFFECTIVENESS DATE:		20160520

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			AmpliPhi Biosciences Corp
    		CENTRAL INDEX KEY:			0000921114
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		IRS NUMBER:				911549568
    		STATE OF INCORPORATION:			WA
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37544
    		FILM NUMBER:		161667122

    	BUSINESS ADDRESS:
    		STREET 1:		3579 VALLEY CENTRE DRIVE
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92130
    		BUSINESS PHONE:		804-827-2524

    	MAIL ADDRESS:
    		STREET 1:		3579 VALLEY CENTRE DRIVE
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92130

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	TARGETED GENETICS CORP /WA/
    		DATE OF NAME CHANGE:	19940331
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>v439550_def14a.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: v439550_def14a.htm

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    <SEQUENCE>2
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    <DESCRIPTION>GRAPHIC
    <TEXT>
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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>sig_jcook.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: sig_jcook.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>spacer.gif
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: spacer.gif

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
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    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: v439550_proxycard-1.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
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    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: v439550_proxycard-2.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>