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Consolidated Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($) | Common Stock [Member] | Additional Paid-in Capital [Member] | Accumulated Deficit [Member] | Series B redeemable convertible preferred stock [Member] | Total
--- | --- | --- | --- | --- | ---
Balances at Dec. 31, 2014 | $ 40,000 | $ 365,403,000 | $ (362,006,000) | $ 1,990,000 | $ 3,437,000
Balances (in shares) at Dec. 31, 2014 | 3,983,182 |  |  | 8,671,040 |
Net loss |  |  | (516,000) |  | (516,000)
Accretion of dividends on Series B redeemable convertible preferred stock |  | (1,307,000) |  | $ 1,307,000 | (1,307,000)
Accretion to redemption value of Series B redeemable convertible preferred stock |  | (8,971,000) |  | 8,971,000 | (8,971,000)
Conversion of Series B redeemable convertible preferred stock to common stock, value | $ 2,000 | 1,504,000 |  | $ (378,000) | 1,506,000
Conversion of Series B redeemable convertible preferred stock to common stock, shares | 228,637 |  |  | (1,143,187) |
Common stock issued in financing, net of offering costs | $ 16,000 | 8,250,000 |  |  | 8,266,000
Common stock issued in financing, net of offering costs (in shares) | 1,575,758 |  |  |  |
Warrants exercised | $ 1,000 | 1,072,000 |  |  | 1,073,000
Warrants exercised (in shares) | 56,645 |  |  |  |
Warrants reclassified from liabilities to equity due to amendment of warrants |  | 5,462,000 |  |  | 5,462,000
Warrants reclassified from liabilities to equity due to increase in authorized shares |  | 3,281,000 |  |  | $ 3,281,000
Exercise of common stock options (shares) | 39,281 |  |  |  | 214,815
Stock-based compensation |  | 479,000 |  |  | $ 479,000
Stock-based compensation - severance |  | 4,000 |  |  | 4,000
Balances at Dec. 31, 2015 | $ 59,000 | 375,177,000 | (362,522,000) | $ 11,890,000 | 12,714,000
Balances (in shares) at Dec. 31, 2015 | 5,883,503 |  |  | 7,527,853 |
Net loss |  |  | (18,838,000) |  | (18,838,000)
Accretion of dividends on Series B redeemable convertible preferred stock |  | (365,000) |  | $ 365,000 | (365,000)
Accretion to redemption value of Series B redeemable convertible preferred stock |  | (1,493,000) |  | 1,493,000 | (1,493,000)
Conversion of Series B redeemable convertible preferred stock to common stock, value | $ 24,000 | 10,605,000 |  | $ (13,748,000) | 10,629,000
Conversion of Series B redeemable convertible preferred stock to common stock, shares | 2,359,025 |  |  | (7,527,853) |
Warrants issued for Novolytics assets (value) |  | 204,000 |  |  | 204,000
Common stock issued in June 2016 financing, net of offering costs and warrants (value) | $ 21,000 | 2,613,000 |  |  | 2,634,000
Common stock issued in June 2016 financing, net of offering costs and warrants (shares) | 2,127,660 |  |  |  |
Common stock issued in November 2016 financing, net of offering costs and warrants (value) | $ 53,000 | 632,000 |  |  | 685,000
Common stock issued in November 2016 financing, net of offering costs and warrants (shares) | 5,335,000 |  |  |  |
Common stock issued pursuant to anti-dilution rights (value) | $ 7,000 | 1,538,000 |  |  | 1,545,000
Common stock issued pursuant to anti-dilution rights (shares) | 750,206 |  |  |  |
Common stock issued under the employee stock purchase plan (value) | $ 1,000 | 12,000 |  |  | 13,000
Common stock issued under the employee stock purchase plan (shares) | 32,726 |  |  |  |
Stock-based compensation |  | 1,995,000 |  |  | 1,995,000
Balances at Dec. 31, 2016 | $ 165,000 | $ 390,918,000 | $ (381,360,000) |  | $ 9,723,000
Balances (in shares) at Dec. 31, 2016 | 16,488,120 |  |  |  |

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