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Income Taxes (Components of Deferred Tax Assets) (Details) - USD ($) | Dec. 31, 2016 | Dec. 31, 2015
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Income Taxes [Abstract] |  |
Net operating loss carry-forwards | $ 67,479,000 | $ 65,425,000
Research and orphan drug credit carry-forwards | 3,109,000 | 5,181,000
Depreciation and amortization | 4,000 | (3,000)
Stock options and other | 1,010,000 | 479,000
Intangible Assets | (2,367,000) | (3,079,000)
Deferred Tax Assets, Gross, Total | 69,235,000 | 68,003,000
Valuation allowance for deferred tax assets | (71,684,000) | (71,008,000)
Deferred Tax Assets, Net, Total | $ (2,449,000) | $ (3,005,000)

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