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Collaborative and Other Agreements (Narrative) (Details) - USD ($) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2016 | Sep. 30, 2016 | Jun. 30, 2016 | Mar. 31, 2016 | Dec. 31, 2015 | Sep. 30, 2015 | Jun. 30, 2015 | Mar. 31, 2015 | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2013
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Licensing payments received | $ 22,000 | $ 29,000 | $ 103,000 | $ 106,000 | $ 128,000 | $ 143,000 | $ 102,000 | $ 102,000 | $ 260,000 | $ 475,000 |
Intrexon Corporation [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Value of common stock paid for technology access fee |  |  |  |  |  |  |  |  |  |  | $ 3,000,000
Fees payable upon commencement of the first Phase 2 trial | 2,500,000 |  |  |  |  |  |  |  | 2,500,000 |  |
Fees payable upon first regulatory approval | $ 5,000,000 |  |  |  |  |  |  |  | 5,000,000 |  |
Milestone payments paid per collaboration agreement |  |  |  |  |  |  |  |  | 0 |  |
Expenses incurred under Channel Collaboration Agreement |  |  |  |  |  |  |  |  | 61,000 | 178,000 |
Cash paid for channel collaboration agreement |  |  |  |  |  |  |  |  | 117,000 | 125,000 |
University Of Leicester [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Expenses incurred under Channel Collaboration Agreement |  |  |  |  |  |  |  |  | 166,000 | 265,000 |
Cash paid for channel collaboration agreement |  |  |  |  |  |  |  |  | 202,000 | 290,000 |
University Of Glasgow [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Expenses incurred under Channel Collaboration Agreement |  |  |  |  |  |  |  |  | 0 | 61,000 |
Cash paid for channel collaboration agreement |  |  |  |  |  |  |  |  | 0 | 61,000 |
Walter Reed Army Institute Of Research [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Payments for services under collaborative agreement |  |  |  |  |  |  |  |  | $ 0 | 0 |
Takara Bio Inc [Member] | Nonsoftware License Arrangement [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Licensing payments received |  |  |  |  |  | $ 40,000 |  |  |  |  |
Percent of license product sales receivable |  |  |  |  |  |  |  |  | 12.00% |  |
Percent of license product service revenues receivable |  |  |  |  |  |  |  |  | 6.00% |  |
Minimum annual royalty payments receivable |  |  |  |  |  |  |  |  | $ 15,000 |  |
Patent license agreement revenue |  |  |  |  |  |  |  |  | 15,000 | $ 0 |
Takara Bio Inc [Member] | Nonsoftware License Arrangement [Member] | Criteria One [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent licensing receivable |  |  |  |  |  |  |  |  | 30,000 |  |
Licensed product revenues milestone benchmark |  |  |  |  |  |  |  |  | 1,000,000 |  |
Takara Bio Inc [Member] | Nonsoftware License Arrangement [Member] | Criteria Two [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent licensing receivable |  |  |  |  |  |  |  |  | 40,000 |  |
Licensed product net sales milestone benchmark |  |  |  |  |  |  |  |  | $ 2,000,000 |  |
Common Stock [Member] | Intrexon Corporation [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Value of common stock paid for technology access fee |  |  |  |  |  |  |  |  |  |  | $ 3,000,000

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