<SEC-DOCUMENT>0001144204-18-053841-index.html : 20181015
<SEC-HEADER>0001144204-18-053841.hdr.sgml : 20181015
<ACCEPTANCE-DATETIME>20181015164417
ACCESSION NUMBER:		0001144204-18-053841
CONFORMED SUBMISSION TYPE:	424B4
PUBLIC DOCUMENT COUNT:		7
FILED AS OF DATE:		20181015
DATE AS OF CHANGE:		20181015

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AmpliPhi Biosciences Corp
		CENTRAL INDEX KEY:			0000921114
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				911549568
		STATE OF INCORPORATION:			WA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B4
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-226959
		FILM NUMBER:		181122643

	BUSINESS ADDRESS:	
		STREET 1:		3579 VALLEY CENTRE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		804-827-2524

	MAIL ADDRESS:	
		STREET 1:		3579 VALLEY CENTRE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TARGETED GENETICS CORP /WA/
		DATE OF NAME CHANGE:	19940331
</SEC-HEADER>
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<TYPE>424B4
<SEQUENCE>1
<FILENAME>tv504787-424b4.htm
<DESCRIPTION>PROSPECTUS
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Document 1 - file: tv504787-424b4.htm

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<FILENAME>lg_ampliphi.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: lg_ampliphi.jpg

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<SEQUENCE>3
<FILENAME>tv501500_slide1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: tv501500_slide1.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>tv501500_slide2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: tv501500_slide2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>tv501500_slide3.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: tv501500_slide3.jpg

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<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>tv501500_slide4.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: tv501500_slide4.jpg

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<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>tv501500_slide5.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: tv501500_slide5.jpg

</DOCUMENT>
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