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Equity Incentive Plans (Tables) | 12 Months Ended
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Dec. 31, 2023
Equity Incentive Plans |
Schedule of Assumptions Used in the Black-Scholes Model | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | Year Ended December 31,
​ |  |  | 2023 | ​ | 2022
Risk-free interest rate | ​ | ​ | 3.54% - 5.54% | ​ | 2.65% - 4.20%
Expected volatility | ​ | ​ | 75.40% - 116.96% | ​ | 81.81% - 85.86%
Expected term (in years) | ​ | ​ | 0.12 - 7.00 | ​ | 5.50 - 7.00
Expected dividend yield | ​ | ​ | 0% | ​ | 0%
Schedule of Stock-Based Compensation Expenses | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended December 31,
​ |  | 2023 |  | 2022
Research and development | ​ | $ | 1,013 | ​ | $ | 1,794
General and administrative | ​ |  | (75) | ​ |  | 1,311
Total stock-based compensation | ​ | $ | 938 | ​ | $ | 3,105
​
Schedule of Stock Option Activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Options Outstanding
​ | ​ | ​ | ​ | ​ | ​ | ​ | Weighted | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Average | ​ | ​ | ​
​ | ​ | ​ | ​ | Weighted | ​ | Remaining | ​ | ​ | ​
​ | ​ | ​ | ​ | Average | ​ | Contractual | ​ | Aggregate
​ | ​ | ​ | ​ | Exercise | ​ | Term | ​ | Intrinsic
​ |  | Shares |  | Price |  | (Years) |  | Value (in thousands)
Outstanding at December 31, 2022 |  | 3,352,803 | ​ | $ | 5.32 |  | 7.8 | ​ | $ | —
Granted |  | 330,266 | ​ | $ | 2.39 |  | ​ |  | $ | —
Exercised | ​ | (1,500) | ​ | $ | 3.15 | ​ | ​ | ​ | $ | 1
Forfeited/Cancelled/Expired |  | (516,353) | ​ | $ | 4.94 |  | ​ |  | $ | 1
Outstanding at December 31, 2023 |  | 3,165,216 | ​ | $ | 5.04 |  | 5.9 | ​ | $ | 429
Vested and expected to vest at December 31, 2023 |  | 3,165,216 | ​ | $ | 5.04 |  | 5.9 | ​ | $ | 429
Exercisable at December 31, 2023 |  | 2,176,275 | ​ | $ | 4.01 |  | 4.0 | ​ | $ | 115
Schedule of restricted stock awards | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | Weighted Avg
​ | ​ | ​ | ​ | Grant Date
​ |  | Shares |  | Fair Value
Outstanding at December 31, 2022 | ​ | 129,666 | ​ | $ | 27.11
Granted | ​ | 200,000 | ​ | $ | 2.39
Forfeited/Cancelled | ​ | (27,341) | ​ | $ | 39.53
Vested and Issued as Common Stock | ​ | (102,325) | ​ | $ | 23.79
Outstanding at December 31, 2023 | ​ | 200,000 | ​ | $ | 2.39

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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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