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Commitments and Contingencies (Details Narrative) - USD ($) |  |  |  | 12 Months Ended
--- | --- | --- | --- | ---
May 19, 2016 | Oct. 02, 2014 | Sep. 30, 2014 | Dec. 31, 2016 | Dec. 31, 2015
Commitments And contingencies [Line Items] |  |  |  |  |
Rent expense |  |  |  | $ 406,308 | $ 409,460
Percentage of maximum compensation |  |  |  | 35.00% |
Percentage of contribute a matching contribution |  |  |  | 50.00% |
Percentage of eligible employee's deferral election |  |  |  | 6.00% |
Matching contributions |  |  |  | $ 27,163 | $ 32,398
Accrued Expenses |  |  |  | $ 91,000 |
Lease Agreement [Member] |  |  |  |  |
Commitments And contingencies [Line Items] |  |  |  |  |
Leases expiration date description |  |  |  | March 2018 |
Royalty and License Agreements [Member] |  |  |  |  |
Commitments And contingencies [Line Items] |  |  |  |  |
Payment of fees |  |  |  | $ 1,800 |
Percentage of royalties payment |  |  |  | 0.005% |
Royalty and License Agreements [Member] | Minimum [Member] |  |  |  |  |
Commitments And contingencies [Line Items] |  |  |  |  |
Gross sales |  |  |  | $ 2,000,000 |
Royalty and License Agreements [Member] | Minimum [Member] | Mr. Messina [Member] | Patents and Copyrights [Member] |  |  |  |  |
Commitments And contingencies [Line Items] |  |  |  |  |
Percentage of royalties payment |  |  |  | 0.0025% |
Gross sales |  |  |  | $ 52,000,000 |
Royalty and License Agreements [Member] | Maximum [Member] |  |  |  |  |
Commitments And contingencies [Line Items] |  |  |  |  |
Gross sales |  |  |  | $ 52,000,000 |
Severance Agreement [Member] | Bill White [Member] |  |  |  |  |
Commitments And contingencies [Line Items] |  |  |  |  |
Stock option vesting period |  |  | 12 months |  |
Agreement term |  |  | 3 years |  |
Executive Employment Agreement [Member] | Dr. William Roof [Member] |  |  |  |  |
Commitments And contingencies [Line Items] |  |  |  |  |
Annual base salary |  | $ 250,000 |  |  |
Salary term description |  | Under the agreement, if Dr. Roof is terminated for any reason other than cause, it would pay Dr. Roof the greater as follows: (a) 12 months if the Separation Date occurs less than 24 months after commencement of Dr. Roof’s employment as Chief Executive Officer, and (b) 24 months if the Separation Date occurs 24 months or more after the commencement of Dr. Roof’s employment as Chief Executive Officer. |  |  |
Executive Employment Agreement [Member] | Mr. Robert Williamsen [Member] |  |  |  |  |
Commitments And contingencies [Line Items] |  |  |  |  |
Annual base salary | $ 225,000 |  |  |  |
Stock-based compensation | $ 149,000 |  |  |  |

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