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Consolidated Statement of Stockholders' Equity - USD ($) | Common Stock [Member] | Additional Paid-In Capital [Member] | Accumulated Deficit [Member] | Total
--- | --- | --- | --- | ---
BALANCE at Dec. 31, 2014 | $ 4,934 | $ 106,442,897 | $ (93,299,794) | $ 13,148,037
BALANCE, shares at Dec. 31, 2014 | 4,934,601 |  |  |
Stock-based compensation expense (employees and directors) |  | 878,112 |  | 878,112
Issuance of common stock, net of costs | $ 4,857 | 7,625,900 |  | 7,630,757
Issuance of common stock, net of costs, Shares | 4,857,143 |  |  |
Exercise of stock options | $ 1 | 3,456 |  | 3,457
Exercise of stock options, shares | 313 |  |  |
Vesting of restricted stock | $ 87 | (87) |  |
Vesting of restricted stock, shares | 86,849 |  |  |
Net loss |  |  | (5,333,951) | (5,333,951)
BALANCE at Dec. 31, 2015 | $ 9,879 | 114,950,278 | (98,633,745) | 16,326,412
BALANCE, shares at Dec. 31, 2015 | 9,878,906 |  |  |
Stock-based compensation expense (employees and directors) |  | 935,899 |  | 935,899
Issuance of common stock, net of costs | $ 1,200 | 1,776,750 |  | 1,776,750
Issuance of common stock, net of costs, Shares | 1,200,000 |  |  |
Purchase and retirement of common stock | $ (979) | (1,095,629) |  | (1,096,608)
Purchase and retirement of common stock, shares | (979,114) |  |  |
Exercise of stock options | $ 345 | 389,534 |  | 389,879
Exercise of stock options, shares | 345,127 |  |  |
Exercise of warrants | $ 153 | 336,447 |  | 389,879
Exercise of warrants, shares | 153,000 |  |  |
Vesting of restricted stock | $ 121 | (121) |  |
Vesting of restricted stock, shares | 120,634 |  |  |
Net loss |  |  | (5,734,681) | (5,734,681)
BALANCE at Dec. 31, 2016 | $ 10,719 | $ 117,293,158 | $ (104,368,426) | $ 12,935,451
BALANCE, shares at Dec. 31, 2016 | 10,718,553 |  |  |

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