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Stock Based Compensation Plan (Tables)
12 Months Ended
Dec. 31, 2022
Share-Based Payment Arrangement [Abstract]  
Summary of stock option activity
A summary of option activity is set forth below (shares in thousands):
 
    
Options Outstanding
 
    
Number of
Options
    
Weighted
Average
Exercise
Price
    
Average
Remaining
Contractual Life
(In years)
    
Aggregate
Intrinsic
Value
(In thousands)
 
Outstanding – December 31, 2021
     1,794      $ 6.31        8.43           
Granted
     2,198        3.26                    
Forfeited
     (79      6.13                    
Expired
     (17      6.77                    
    
 
 
                            
Outstanding – December 31, 2022
     3,896        2.43        8.44      $ —    
    
 
 
                            
Exercisable – December 31, 2022
     1,430        1.94        7.48        —    
    
 
 
                            
Summary of RSA Activity
The following table summarizes the Company’s RSA activity (shares in thousands):
 
    
Number of
Shares
    
Weighted
Average
Grant Date
Fair Value
 
RSAs, unvested at December 31, 2021
     161      $ 9.39  
Vested
     (56      8.72  
    
 
 
          
RSAs, unvested at December 31, 2022
     105        9.74  
    
 
 
          
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions
The fair value of options is estimated at the grant date using the Black-Scholes option pricing model with the following weighted-average assumptions:
 
    
Year Ended
December 31,
 
    
2022
   
2021
 
Expected term (in years)
     6.00       6.01  
Expected volatility
     81.07     71.23
Risk-free rate
     2.03     0.89
Dividend yield
     —         —    
Schedule of Stock-Based Compensation Expense
Total stock-based compensation recorded in the consolidated statements of operations and comprehensive loss related to options and RSAs was as follows (in thousands):
 
    
Year Ended
December 31,
 
    
2022
    
2021
 
Research and development
   $ 1,612      $ 736  
General and administrative
     2,905        1,580  
    
 
 
    
 
 
 
Total stock-based compensation expense
   $ 4,517      $ 2,316