<SEC-DOCUMENT>0001062993-21-011100-index.html : 20211117
<SEC-HEADER>0001062993-21-011100.hdr.sgml : 20211117
<ACCEPTANCE-DATETIME>20211117201915
ACCESSION NUMBER:		0001062993-21-011100
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20211115
FILED AS OF DATE:		20211117
DATE AS OF CHANGE:		20211117

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			McIlwain Matthew S
		CENTRAL INDEX KEY:			0001381752

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39434
		FILM NUMBER:		211422272

	MAIL ADDRESS:	
		STREET 1:		1000 SECOND AVENUE
		STREET 2:		SUITE 3700
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98104

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Nautilus Biotechnology, Inc.
		CENTRAL INDEX KEY:			0001808805
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2701 EASTLAKE AVE EAST
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98102
		BUSINESS PHONE:		206-333-2001

	MAIL ADDRESS:	
		STREET 1:		2701 EASTLAKE AVE EAST
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98102

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ARYA Sciences Acquisition Corp III
		DATE OF NAME CHANGE:	20200408
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4.xml
<DESCRIPTION>STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
<TEXT>
Document 1 - file: form4.html

Document 1 - RAW XML: form4.xml

</DOCUMENT>
</SEC-DOCUMENT>