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Cover
Mar. 30, 2022
Cover [Abstract]  
Document Type 8-K
Document Period End Date Mar. 30, 2022
Entity Registrant Name NAUTILUS BIOTECHNOLOGY, INC.
Entity Incorporation, State or Country Code DE
Entity File Number 001-39434
Entity Tax Identification Number 98-1541723
Entity Address, Address Line One 2701 Eastlake Avenue East
Entity Address, City or Town Seattle
Entity Address, State or Province WA
Entity Address, Postal Zip Code 98102
City Area Code 206
Local Phone Number 333-2001
Written Communications false
Soliciting Material false
Pre-commencement Tender Offer false
Pre-commencement Issuer Tender Offer false
Title of 12(b) Security Common Stock, par value $0.0001 per share
Trading Symbol NAUT
Security Exchange Name NASDAQ
Entity Emerging Growth Company true
Entity Ex Transition Period false
Entity Central Index Key 0001808805
Amendment Flag false
Entity Addresses [Line Items]  
Entity Address, Address Line One 2701 Eastlake Avenue East
Entity Address, City or Town Seattle
Entity Address, State or Province WA
Entity Address, Postal Zip Code 98102
FALSE Mar. 30, 2022