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Commitments and Contingencies - Narrative (Details) $ in Thousands | 1 Months Ended | 12 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Dec. 31, 2025 USD ($) institution | Dec. 31, 2025 USD ($) institution | Dec. 31, 2024 USD ($) | Nov. 30, 2022 USD ($) | Dec. 31, 2021 USD ($) | Aug. 31, 2021 USD ($) | Jul. 31, 2021 | Dec. 31, 2020 USD ($)
Lessee, Lease, Description [Line Items] |  |  |  |  |  |  |  |
Open purchase commitment |  | $ 1,500 |  |  |  |  |  |
Open purchase commitment to be received through next 12 months | $ 1,400 | 1,400 |  |  |  |  |  |
Term of contract (in years) |  |  |  |  |  |  | 7 years |
Total minimum lease payments | 38,233 | 38,233 |  |  |  | $ 4,500 |  |
Operating lease liabilities | 4,200 | (4,688) | $ (4,150) |  |  |  |  |
Amortization of operating lease right-of-use assets | $ 4,200 | 4,712 | 4,378 |  |  |  |  |
Cash paid for lease liabilities included in operating activities |  | $ 7,200 | $ 7,000 |  |  |  |  |
Weighted average remaining lease term | 5 years 7 months 6 days | 5 years 7 months 6 days |  |  |  |  |  |
Weighted average discount rate (in percent) | 9.00% | 9.00% |  |  |  |  |  |
Cash-collateralized letters of credit | $ 1,000 | $ 1,000 |  |  |  |  |  |
Number of financial institution | institution | 1 | 1 |  |  |  |  |  |
San Carlos |  |  |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |  |  |
Interest rate on financing for tenant improvements (in percent) |  |  |  |  | 7.00% |  |  |
San Carlos | Maximum |  |  |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |  |  |
Tenant improvement financing |  |  |  |  | $ 2,000 |  |  |
San Diego |  |  |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |  |  |
Term of contract (in years) |  |  |  | 39 months |  |  |  |
Total minimum lease payments |  |  |  | $ 2,100 |  |  |  |
October 2021 to October 2031 |  |  |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |  |  |
Term of contract (in years) |  |  |  |  |  |  |  | 10 years
Total minimum lease payments |  |  |  |  |  |  |  | $ 40,700
March 2023 To March 2032 |  |  |  |  |  |  |  |
Lessee, Lease, Description [Line Items] |  |  |  |  |  |  |  |
Term of contract (in years) |  |  |  |  | 9 years |  |  |
Total minimum lease payments |  |  |  |  | $ 7,200 |  |  |
Lease term with option to terminate (in years) |  |  |  |  | 5 years |  |  |

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