XML 23 R1.htm IDEA: XBRL DOCUMENT v3.25.4
Cover - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2025
Feb. 19, 2026
Jun. 30, 2025
Cover [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2025    
Current Fiscal Year End Date --12-31    
Document Transition Report false    
Entity File Number 001-39434    
Entity Registrant Name NAUTILUS BIOTECHNOLOGY, INC.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 98-1541723    
Entity Address, Address Line One 2701 Eastlake Avenue East    
Entity Address, City or Town Seattle    
Entity Address, State or Province WA    
Entity Address, Postal Zip Code 98102    
City Area Code 206    
Local Phone Number 333-2001    
Title of 12(b) Security Common Stock, par value $0.0001 per share    
Trading Symbol NAUT    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag false    
Document Financial Statement Error Correction [Flag] false    
Entity Shell Company false    
Entity Public Float     $ 35.8
Entity Common Stock, Shares Outstanding   126,564,473  
Documents Incorporated by Reference
Portions of the registrant’s definitive Proxy Statement to be filed with the Securities and Exchange Commission in connection with the registrant’s 2026 Annual Meeting of Stockholders, which will be filed subsequent to the date hereof, are incorporated by reference into Part III of this Form 10-K. Such Proxy Statement will be filed with the Securities and Exchange Commission not later than 120 days following the end of the registrant’s fiscal year ended December 31, 2025. Except with respect to information specifically incorporated by reference, the Proxy Statement is not deemed to be filed as part of this Annual Report on Form 10-K.
    
Entity Central Index Key 0001808805    
Amendment Flag false    
Document Fiscal Year Focus 2025    
Document Fiscal Period Focus FY