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Segment Information - Schedule of Significant Segment Expenses (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Segment Reporting Information [Line Items]    
Total operating expenses $ 66,837 $ 81,476
Interest income 7,868 10,780
Other expense 32 84
Net loss (59,001) (70,780)
Reportable Segment    
Segment Reporting Information [Line Items]    
Payroll-related expenses 30,981 33,502
Professional services and laboratory expenses 11,910 17,716
Stock-based compensation expense 6,844 12,701
Facilities expenses 11,534 10,902
Other segment items 5,568 6,655
Total operating expenses 66,837 81,476
Interest income (7,868) (10,780)
Other expense 32 84
Net loss $ 59,001 $ 70,780