<SEC-DOCUMENT>0001808805-26-000023-index.html : 20260428
<SEC-HEADER>0001808805-26-000023.hdr.sgml : 20260428
<ACCEPTANCE-DATETIME>20260428160924
ACCESSION NUMBER:		0001808805-26-000023
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		7
CONFORMED PERIOD OF REPORT:	20260617
FILED AS OF DATE:		20260428
DATE AS OF CHANGE:		20260428

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Nautilus Biotechnology, Inc.
		CENTRAL INDEX KEY:			0001808805
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				981541723
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39434
		FILM NUMBER:		26907779

	BUSINESS ADDRESS:	
		STREET 1:		2701 EASTLAKE AVE EAST
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98102
		BUSINESS PHONE:		206-333-2001

	MAIL ADDRESS:	
		STREET 1:		2701 EASTLAKE AVE EAST
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98102

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ARYA Sciences Acquisition Corp III
		DATE OF NAME CHANGE:	20200408
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>nautilusdef14a20260617a.htm
<DESCRIPTION>DEF 14A
<TEXT>
Document 1 - file: nautilusdef14a20260617a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>capvsnetincome-4926a.jpg
<TEXT>
Document 2 - file: capvsnetincome-4926a.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>capvstsr-withoutnasdaqtsr4a.jpg
<TEXT>
Document 3 - file: capvstsr-withoutnasdaqtsr4a.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>nautilus2025proxycard001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: nautilus2025proxycard001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>nautilus2025proxycard002.jpg
<TEXT>
Document 5 - file: nautilus2025proxycard002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>nautilus_primarylogoxbluea.jpg
<TEXT>
Document 6 - file: nautilus_primarylogoxbluea.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>sujalsignaturea.jpg
<TEXT>
Document 7 - file: sujalsignaturea.jpg

</DOCUMENT>
</SEC-DOCUMENT>