XML 17 R1.htm IDEA: XBRL DOCUMENT v3.26.1
Document and Entity Information - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Mar. 23, 2026
Jun. 30, 2025
Document and Entity Information        
Document Type 10-K      
Document Annual Report true      
Document Period End Date Dec. 31, 2025      
Current Fiscal Year End Date --12-31      
Document Fiscal Year Focus 2025      
Document Transition Report false      
Entity File Number 001-38365      
Entity Registrant Name HYPERION DEFI, INC.      
Entity Incorporation, State or Country Code DE      
Entity Tax Identification Number 47-1178401      
Entity Address, Address Line One 23461 South Point Drive, Suite 390      
Entity Address, City or Town Laguna Hills      
Entity Address, State or Province CA      
Entity Address, Postal Zip Code 92653      
City Area Code 833      
Local Phone Number 393-6684      
Title of 12(b) Security Common Stock, $0.0001 Par Value      
Trading Symbol HYPD      
Security Exchange Name NASDAQ      
Entity Well-known Seasoned Issuer No      
Entity Voluntary Filers No      
Entity Current Reporting Status Yes      
Entity Interactive Data Current Yes      
Entity Filer Category Non-accelerated Filer      
Entity Small Business true      
Entity Emerging Growth Company false      
ICFR Auditor Attestation Flag false      
Document Financial Statement Error Correction [Flag] false      
Entity Shell Company false      
Auditor Firm ID 199 688    
Auditor Name CBIZ CPAs P.C. Marcum LLP    
Auditor Location Philadelphia, PA New York, New York    
Entity Public Float       $ 50.1
Entity Common Stock, Shares Outstanding     11,391,645  
Documents Incorporated by Reference [Text Block]

None.

      
Entity Central Index Key 0001682639      
Document Fiscal Period Focus FY      
Amendment Flag false