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Collaboration and License Agreements - Additional Information (Details) | 1 Months Ended | 3 Months Ended |
--- | --- | --- | ---
Mar. 31, 2020 USD ($) Target | Mar. 31, 2023 USD ($) | Mar. 31, 2022 USD ($) | Dec. 31, 2022 USD ($)
Collaboration And License Agreements [Line Items] |  |  |  |
Collaboration and license revenue |  | $ 6,803,000 | $ 3,021,000 |
Incurred costs |  | $ 29,546,000 | 19,184,000 |
Deferred revenue, current portion |  |  |  | $ 3,874,000
Maximum | Novartis Agreement |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |
Ownership Interest |  | 10.00% |  |
Minimum | Novartis Agreement |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |
Ownership Interest | 10.00% |  |  |
Novartis |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |
License agreement date | Mar. 31, 2020 |  |  |
Upfront payment received | $ 20,000,000.0 |  |  |
Upfront payment receivable | $ 20,000,000.0 |  |  |
Negotiation period |  | 180 days |  |
Collaboration and license revenue |  | $ 5,800,000 | 3,000,000.0 |
Incurred costs |  | 1,900,000 | $ 1,000,000.0 |
Deferred revenue |  | $ 0 |  |
Novartis | Maximum |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |
Number of targets identified | Target | 3 |  |  |
Novartis | Research Funding |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |
Upfront payment received | $ 10,000,000.0 |  |  |
Upfront payment receivable | $ 10,000,000.0 |  |  |

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