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Collaboration and License Agreements - Additional Information (Details) - USD ($) $ in Thousands |  |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
May 08, 2023 | Mar. 31, 2020 | Mar. 31, 2020 | Dec. 31, 2024 | Dec. 31, 2023
Collaboration And License Agreements [Line Items] |  |  |  |  |
Collaboration and license revenue |  |  |  | $ 2,816 | $ 21,049
Incurred costs |  |  |  | 137,637 | 114,507
Deferred revenue, current portion |  |  |  | 11,698 | 10,137
Long-term deferred revenue |  |  |  | $ 1,246 | $ 5,622
Maximum | Novartis Agreement |  |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |  |
Ownership Interest |  |  |  | 10.00% | 10.00%
Minimum | Novartis Agreement |  |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |  |
Ownership Interest |  | 10.00% | 10.00% |  |
Amgen Inc. | Amgen Agreement |  |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |  |
License agreement date | May 08, 2023 |  |  |  |
Upfront payment receivable | $ 30,000 |  |  |  |
Potential milestone payment | $ 500,000 |  |  |  |
Expects research term | 3 years |  |  |  |
Collaboration and license revenue |  |  |  | $ 2,800 | $ 14,200
Deferred revenue |  |  |  | 12,900 |
Long-term deferred revenue |  |  |  | $ 1,200 |
Novartis |  |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |  |
License agreement date |  |  | Mar. 31, 2020 |  |
Upfront payment receivable |  | $ 20,000 | $ 20,000 |  |
Collaboration and license revenue |  |  |  |  | 5,800
Reimbursement cost |  |  |  |  | $ 1,900
Novartis | Research Funding |  |  |  |  |
Collaboration And License Agreements [Line Items] |  |  |  |  |
Upfront payment received |  |  | $ 10,000 |  |

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