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Segment Reporting | 12 Months Ended
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Dec. 31, 2024
Segment Reporting [Abstract] |
Segment Reporting | 13. Segment Reporting Operating segments are defined as components of the entity for which separate financial information is made available and that is regularly evaluated by the chief operating decision maker (CODM) in making decisions regarding resource allocation and assessing performance. The Company's CODM is its chief executive officer and the Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. The Company is focused on the development of T cell receptor (TCR)-engineered T cell (TCR-T) therapies for the treatment of patients with cancer. The CODM assesses the Company's performance by reviewing GAAP net loss and significant expenses by function along with the annual budget. The chief operating decision maker considers budget-to-actual variances on a quarterly basis when making decisions about the allocation of operating and capital resources. The following table provides information about the Company's single operating segment which includes significant expenses by function along with significant non-cash expense items.
| Year Ended December 31, |
| 2024 |  |  | 2023 |
Revenue: |  |  |  |  |
Collaboration and license revenue |  | 2,816 |  |  |  | 21,049 |
Operating expenses: |  |  |  |  |
Research and development: |  |  |  |  |
Personnel expenses |  | 31,742 |  |  |  | 24,165 |
Laboratory supplies, research materials and studies |  | 31,468 |  |  |  | 30,101 |
Clinical studies |  | 19,245 |  |  |  | 10,214 |
Facility-related and other |  | 16,669 |  |  |  | 16,298 |
Stock-based compensation |  | 4,846 |  |  |  | 2,876 |
Depreciation expense |  | 3,380 |  |  |  | 4,499 |
General and administrative: |  |  |  |  |
Personnel expenses |  | 10,900 |  |  |  | 9,065 |
Legal and professional fees |  | 7,380 |  |  |  | 7,119 |
Facility-related and other |  | 6,576 |  |  |  | 6,976 |
Stock-based compensation |  | 4,703 |  |  |  | 2,332 |
Depreciation Expense |  | 728 |  |  |  | 862 |
Loss from operations |  | (134,821 | ) |  |  | (93,458 | )
Other (expense) income: |  |  |  |  |
Interest and other income, net |  | 12,065 |  |  |  | 7,999 |
Interest expense |  | (3,653 | ) |  |  | (3,759 | )
Loss on extinguishment of debt |  | (1,090 | ) |  |  | - |
Net Loss |  | (127,499 | ) |  |  | (89,218 | )

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 55 -Paragraph 48 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482785/280-10-55-48 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards 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