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Segment Reporting | 6 Months Ended
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Jun. 30, 2026
Segment Reporting [Abstract] |
Segment Reporting | 9. Segment Reporting Operating segments are defined as components of the entity for which separate financial information is made available and that is regularly evaluated by the chief operating decision maker (CODM) in making decisions regarding resource allocation and assessing performance. The Company's CODM is its Chief Executive Officer and the Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. The Company is focused on the development of TCR-T therapy product candidates for the treatment of patients with cancer. The CODM assesses the Company's performance by reviewing GAAP net loss and significant expenses by function along with the annual budget. The CODM considers budget-to-actual variances on a quarterly basis when making decisions about the allocation of operating and capital resources. The following table provides information about the Company's single operating segment which includes significant expenses by function along with significant non-cash expense items.
| Three Months Ended June 30, |  |  | Six Months Ended June 30, |
| 2026 |  |  | 2025 |  |  | 2026 |  |  | 2025 |
Revenue: |  |  |  |  |  |  |  |  |  |  |
Collaboration and license revenue | $ | 1,051 |  |  | $ | 3,076 |  |  | $ | 2,033 |  |  | $ | 5,247 |
Operating expenses: |  |  |  |  |  |  |  |  |  |  |
Research and development: |  |  |  |  |  |  |  |  |  |  |
Personnel expenses |  | 6,909 |  |  |  | 8,966 |  |  |  | 15,240 |  |  |  | 17,782 |
Facility-related and other |  | 5,367 |  |  |  | 5,657 |  |  |  | 9,932 |  |  |  | 11,205 |
Laboratory supplies, research materials and studies |  | 5,297 |  |  |  | 12,101 |  |  |  | 9,575 |  |  |  | 21,590 |
Clinical studies |  | 4,017 |  |  |  | 3,721 |  |  |  | 6,907 |  |  |  | 7,416 |
Stock-based compensation |  | 1,197 |  |  |  | 1,668 |  |  |  | 2,428 |  |  |  | 3,406 |
Depreciation expense |  | 615 |  |  |  | 521 |  |  |  | 1,224 |  |  |  | 1,023 |
General and administrative: |  |  |  |  |  |  |  |  |  |  |
Personnel expenses |  | 2,604 |  |  |  | 3,337 |  |  |  | 6,121 |  |  |  | 6,356 |
Legal and professional fees |  | 2,520 |  |  |  | 2,041 |  |  |  | 4,212 |  |  |  | 3,995 |
Facility-related and other |  | 1,774 |  |  |  | 1,935 |  |  |  | 3,464 |  |  |  | 3,743 |
Stock-based compensation |  | 1,160 |  |  |  | 1,606 |  |  |  | 2,394 |  |  |  | 3,281 |
Depreciation expense |  | 84 |  |  |  | 176 |  |  |  | 168 |  |  |  | 353 |
Other (expense) income: |  |  |  |  |  |  |  |  |  |  |
Interest and other income, net |  | 833 |  |  |  | 2,390 |  |  |  | 1,995 |  |  |  | 5,192 |
Interest expense |  | (699 | ) |  |  | (689 | ) |  |  | (1,388 | ) |  |  | (1,368 | )
Net loss | $ | (30,359 | ) |  | $ | (36,952 | ) |  | $ | (59,025 | ) |  | $ | (71,079 | )

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