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Income Taxes - Summary of Significant Components of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
--- | --- | --- | --- | ---
Deferred tax assets: |  |  |  |
Net operating loss carryforwards | $ 258,002 | $ 229,264 |  |
Research and development credit carryforwards | 15,234 | 1,660 |  |
Deferred revenue | 298 | 2,687 |  |
Deferred compensation | 7,571 | 5,687 |  |
Leasing obligation | 2,138 | 3,087 |  |
Capitalized research expense | 45,670 | 43,476 |  |
Other | 3,736 | 2,415 |  |
Total deferred tax assets | 332,648 | 288,276 |  |
Total valuation allowance | 313,147 | 263,001 | $ 214,776 | $ 164,391
Total net deferred tax assets | 19,501 | 25,275 |  |
Deferred tax liabilities: |  |  |  |
Joint venture investment basis difference | (841) | (1,054) |  |
Intangibles | (15,800) | (20,879) |  |
Right-of-use assets | (1,878) | (2,738) |  |
Other | (2,006) | (1,902) |  |
Total deferred tax assets (liabilities) | (20,525) | (26,573) |  |
Net deferred tax liabilities | $ (1,024) | $ (1,298) |  |

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