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Condensed Consolidated Statements of Stockholders Equity - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive (Loss)/Income
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2019   67,329,000      
Beginning balance at Dec. 31, 2019 $ 174,957 $ 7 $ 560,704 $ (725) $ (385,029)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Stock-based compensation expense 3,409   3,409    
Issuance of common stock, net of issuance costs (in shares)   10,925,000      
Issuance of common stock, net of issuance costs 140,873 $ 1 140,872    
Common stock issued upon exercise of stock options (in shares)   1,310,000      
Common stock issued upon exercise of stock options 9,650   9,650    
Common stock issued upon net exercise of warrants (in shares)   7,000      
Common stock issued upon release of restricted stock units (in shares)   462,000      
Restricted stock surrendered for taxes (in shares)   (155,000)      
Restricted stock surrendered for taxes (1,922)   (1,922)    
Foreign currency translation adjustments (54)     (54)  
Unrealized gain (loss) on marketable securities, net (54)     (54)  
Net loss (22,906)       (22,906)
Ending balance (in shares) at Mar. 31, 2020   79,878,000      
Ending balance at Mar. 31, 2020 303,953 $ 8 712,713 (833) (407,935)
Beginning balance (in shares) at Dec. 31, 2019   67,329,000      
Beginning balance at Dec. 31, 2019 174,957 $ 7 560,704 (725) (385,029)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Foreign currency translation adjustments 0        
Unrealized gain (loss) on marketable securities, net 120        
Net loss (79,875)        
Ending balance (in shares) at Sep. 30, 2020   97,467,000      
Ending balance at Sep. 30, 2020 464,712 $ 10 930,211 (605) (464,904)
Beginning balance (in shares) at Mar. 31, 2020   79,878,000      
Beginning balance at Mar. 31, 2020 303,953 $ 8 712,713 (833) (407,935)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Stock-based compensation expense 4,785   4,785    
Common stock issued upon exercise of stock options (in shares)   643,000      
Common stock issued upon exercise of stock options 2,487   2,487    
Common stock issued upon release of restricted stock units (in shares)   66,000      
Issuance of common stock, additional issuance costs (51)   (51)    
Common stock issued under employee stock purchase plan (in shares)   57,000      
Common stock issued under employee stock purchase plan 475   475    
Restricted stock surrendered for taxes (in shares)   (5,000)      
Restricted stock surrendered for taxes (121)   (121)    
Taxes paid for RSUs 0   0    
Foreign currency translation adjustments 41     41  
Unrealized gain (loss) on marketable securities, net 194     194  
Net loss (29,200)       (29,200)
Ending balance (in shares) at Jun. 30, 2020   80,639,000      
Ending balance at Jun. 30, 2020 282,563 $ 8 720,288 (598) (437,135)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Stock-based compensation expense 6,020   6,020    
Issuance of common stock, net of issuance costs (in shares)   16,675,000      
Issuance of common stock, net of issuance costs 203,383 $ 2 203,381    
Common stock issued upon exercise of stock options (in shares)   83,000      
Common stock issued upon exercise of stock options 516   516    
Common stock issued upon net exercise of warrants (in shares)   29,000      
Common stock issued upon release of restricted stock units (in shares)   43,000      
Common stock issued under employee stock purchase plan (in shares)   1,000      
Common stock issued under employee stock purchase plan 6   6    
Restricted stock surrendered for taxes (in shares)   (3,000)      
Foreign currency translation adjustments 13     13  
Unrealized gain (loss) on marketable securities, net (20)     (20)  
Net loss (27,769)       (27,769)
Ending balance (in shares) at Sep. 30, 2020   97,467,000      
Ending balance at Sep. 30, 2020 464,712 $ 10 930,211 (605) (464,904)
Beginning balance (in shares) at Dec. 31, 2020   97,549,000      
Beginning balance at Dec. 31, 2020 434,347 $ 10 937,134 (261) (502,536)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Stock-based compensation expense 7,224   7,224    
Issuance of common stock, net of issuance costs (in shares)   121,000      
Issuance of common stock, net of issuance costs 1,689   1,689    
Common stock issued upon exercise of stock options (in shares)   9,000      
Common stock issued upon exercise of stock options 51   51    
Common stock issued upon release of restricted stock units (in shares)   248,000      
Restricted stock surrendered for taxes (in shares)   0      
Restricted stock surrendered for taxes 0        
Foreign currency translation adjustments (33)     (33)  
Unrealized gain (loss) on marketable securities, net (22)     (22)  
Net loss (28,436)       (28,436)
Ending balance (in shares) at Mar. 31, 2021   97,927,000      
Ending balance at Mar. 31, 2021 414,820 $ 10 946,098 (316) (530,972)
Beginning balance (in shares) at Dec. 31, 2020   97,549,000      
Beginning balance at Dec. 31, 2020 $ 434,347 $ 10 937,134 (261) (502,536)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Common stock issued upon exercise of stock options (in shares) 9,000        
Foreign currency translation adjustments $ (123)        
Unrealized gain (loss) on marketable securities, net (139)        
Net loss (111,131)        
Ending balance (in shares) at Sep. 30, 2021   98,143,000      
Ending balance at Sep. 30, 2021 346,000 $ 10 960,180 (523) (613,667)
Beginning balance (in shares) at Mar. 31, 2021   97,927,000      
Beginning balance at Mar. 31, 2021 414,820 $ 10 946,098 (316) (530,972)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Stock-based compensation expense 8,234   8,234    
Common stock issued upon release of restricted stock units (in shares)   17,000      
Issuance of common stock, additional issuance costs (4)   (4)    
Common stock issued under employee stock purchase plan (in shares)   176,000      
Common stock issued under employee stock purchase plan 526   526    
Foreign currency translation adjustments (39)     (39)  
Unrealized gain (loss) on marketable securities, net (62)     (62)  
Net loss (44,333)       (44,333)
Ending balance (in shares) at Jun. 30, 2021   98,120,000      
Ending balance at Jun. 30, 2021 379,142 $ 10 954,854 (417) (575,305)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Stock-based compensation expense 5,326   5,326    
Common stock issued upon release of restricted stock units (in shares)   23,000      
Foreign currency translation adjustments (51)     (51)  
Unrealized gain (loss) on marketable securities, net (55)     (55)  
Net loss (38,362)       (38,362)
Ending balance (in shares) at Sep. 30, 2021   98,143,000      
Ending balance at Sep. 30, 2021 $ 346,000 $ 10 $ 960,180 $ (523) $ (613,667)